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国际医学放射学杂志 2019年第1期 103-104页

作者： H.Takagi H.Ota R.Umezawa T.Kimura N.Kadoya s.higuchi 王佳佳 Department of Diagnostic Radiology Tohoku University Graduate School of Medicine

摘要目的用MRI评估食管癌化放疗后病人左心室功能和组织成分的改变。材料与方法本项前瞻性研究纳入2013年1月—2015年4月期间24例计划行化放疗的病人

关键词：化放疗 MRI T1 mapping 食管癌左心室

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退化结构最优化修复的成本效益分析

钢结构(中英文) 2008年第12期 83-83页

作者： s.higuchi M.Macke

提出了一个针对老化结构修复的成本效益分析,考虑了建筑生命周期内的所有成本,如施工、失效、检测和基于状态的修复成本,也考虑了其基于状态或者时间的收益率。任何时候都可以对结构进行修复,并通过最大化其预期当前收益率来达到优化目... 详细信息

提出了一个针对老化结构修复的成本效益分析,考虑了建筑生命周期内的所有成本,如施工、失效、检测和基于状态的修复成本,也考虑了其基于状态或者时间的收益率。任何时候都可以对结构进行修复,并通过最大化其预期当前收益率来达到优化目的。这个方法不仅可以决定修复的最优次序和修复等级,而且可以决定最优使用寿命和可接受的失效率。数值算例证明:对修复合适的规划可以延长结构的使用寿命,直到预算超出预期的结构收益为止。如果不这样,结构将会退化失效,届时需评估其他的替代方法。

关键词：成本效益分析老化修复结构安全最优化

Biomass Control via UV Lamp Application and Nutrient supply Restriction in the Biofiltration of Gaseous VOCs

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Journal of Environmental science and Engineering(B) 2024年第3期13卷 97-104页

作者： Takashi higuchi Kokoro Hashizume school of science and Engineering Ritsumeikan University1-1-1 Noji-higashiKusatsuShiga 525-8577Japan Graduate school of science and Engineering Ritsumeikan University1-1-1 Noji-higashiKusatsuShiga 525-8577Japan

Biofiltration may have clogging problems owing to excess biomass growth during the treatment of gaseous *** this study,we employed an UV(Ultraviolet)lamp and controlled the nutrient supply to conduct a biofiltration process for treating 2-butanone(MEK:Methyl Ethyl Ketone)and toluene in a gas *** methods of UV lamp usage(direct and indirect irradiation)and several nutrient supply methods were ***,no clear effect was observed with either UV *** the optimal conditions,97%of the MEK and 69%of the toluene gases were removed after 29 s of EBRT(Empty Bed Retention Time).The inlet loads were 18 and 19 mg/(m^(3)·h)for MEK and toluene,*** these conditions,23 g-N/(m^(3)·day)of nitrate-nitrogen was *** biomass growth occurred during simultaneous excess nutrient supply and a persistent irrigation *** this study,we demonstrated the effective use of a dense nitrate solution to deliver an appropriate amount of nutrients and moisture,and the optimal irrigation frequency was four times per week.

关键词： Biofiltration gaseous VOCs(Volatile Organic Compounds) nutrient supply UV lamp ozone

Detection and clearance in Alzheimer’s disease: leading with illusive chemical, structural and morphological features of the targets

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Neural Regeneration Research 2024年第3期19卷 497-498页

作者： Luís Gales i3s−Instituto de Investigação e Inovação em saúde Rua Alfredo AllenPortoPortugal(Gales L)IBMC−Instituto de Biologia Molecular e CelularUniversidade do PortoRua Alfredo AllenPortoPortugal ICBAs−Instituto de Ciências Biomédicas Abel salazar Rua de Jorge Viterbo FerreiraPortoPortugal

Highly specific interactions between biomolecules,such as antigen-antibody,protein-ligand,or nucleic acid base pair complementary are on the basis of the organization of complex *** same principles may be tentatively used in molecular medicine for diagnosis and therapeutics.A molecule can be designed to selectively bind a protease and thereby inhibit the production of a peptide that forms toxic aggregates in the brain or an antibody may be produced to bind specifically to that peptide for detection or clearance ***,interference in biological systems is not that *** a start there is the inhibition of the physiological role of the protease;moreover,several cleavage fragments may be produced,which may continue to diverge due to putative post-translational modification and self-assembly processes,hiding the toxic target in a“soup”of peptide species varying in size,structure and chemical composition.A perspective of the current status and challenges in targeting peptide species for diagnosis and treatment in the context of Alzheimer’s disease is given.

关键词： Alzheimer diagnosis thereby

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No-touch isolation technique in emergency pancreaticoduodenectomy for neoplastic hemorrhage: Two case reports and review of literature

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World Journal of Gastrointestinal surgery 2024年第6期16卷 1910-1917页

作者： Akihiro Cho satoshi Katagiri Masao Ota shunsuke Onizawa Ryota higuchi Toshiya sugishita Yukiko Niwa Takeshi Ishita Toshihiko Mouri Akita Kato Moe Iwata Division of Gastroenterological surgery Tokyo Women’s Medical UniversityYachiyo Medical CenterChiba 276-8524Japan

BACKGROUND Emergency pancreaticoduodenectomy(EPD)is a rare event for complex periam-pullary *** intraoperative blood loss is correlated with poor post-operative *** sUMMARY Two patients underwent EPD using a no-touch isolation technique,in which all arteries supplying the pancreatic head region were ligated and divided before manipulation of the pancreatic head and *** operative times were 220 and 239 min,and the blood loss was 70 and 270 g,*** patients were discharged on the 14^(th) and 10^(th) postoperative day,***-two patients underwent EPD for the treatment of neoplastic *** mean operative time was 361.6 min,and the mean blood loss was 747.3 *** comp-lication rate was 37.5%.The in-hospital mortality rate was 9.38%.CONCLUsION The no-touch isolation technique is feasible,safe,and effective for reducing intraoperative blood loss in EPD.

关键词： No-touch isolation technique Pancreaticoduodenectomy Emergency pancre-aticoduodenectomy Neoplastic bleeding superior mesenteric artery first approach Case report

Model dependent analysis of D^(+)_(s)→η^(′)l+v_(l) decays in beyond standard model

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Chinese Physics C 2024年第9期48卷 82-95页

作者： s.Mahata M.Mandal H.Mahapatra s.Biswas s.sahoo Department of Physics National Institute of Technology Durgapur Durgapur 713209West BengalIndia

Motivated by the recent experimental results of branching fractions for D^(+)_(s)→η^(′)l+v_(l) decays,which deviate from their sM predictions,we hve investigated these decays in W' model and scalar leptoquark model to determine potential signatures of new physics(NP) in semileptonic charm decays induced by c→(s,d)l+v_(l) *** recent experimental results of branching fractions for semileptonic D meson decays,new coupling parameters are predicted for the aforementioned NP *** fraction,forward-backward asymmetry,and lepton polarization asymmetry are examined by considering the predicted NP coupling *** results of branching fractions in scalar leptoquark model are found very close to the experimental results and exist around the range of 1σ *** presented a comparative study of the NP models to check their sensitivity on these *** anticipate that further research on these decays will significantly support our findings.

关键词： charm decay new physics W′boson scalar leptoquark flavour changing charged current

Astrophysical s-factor and reaction rate for 15N(p,γ)16O within the modified potential cluster model

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Chinese Physics C 2024年第4期48卷 130-145页

作者： s.B.Dubovichenko A.s.Tkachenko R.Ya.Kezerashvili N.A.Burkova B.M.Yeleusheva Fesenkov Astrophysical Institute 050020 AlmatyKazakhstan New York City College of Technology City University of New YorkBrooklyn11201 New YorkUSA Graduate school and University Center City University of New York10016 New YorkUSA al-Farabi Kazakh National University 050040 AlmatyKazakhstan

We study radiative p^(15)N capture on the ground state of ^(16)O at stellar energies within the framework of a modified potential cluster model(MPCM)with forbidden states,including low-lying *** investigation of the ^(15)N(p,γ0)^(16)O reaction includes the consideration of ^(3)s_(1) resonances due to E1 transitions and the contribution of the ^(3)P_(1) scattering wave in the p+^(15)N channel due to the ^(3)P_(1)→^(3)P_(0)M1 *** calculated the astrophysical low-energy s-factor,and the extrapolated s(0)turned out to be within 34.7−40.4 keV·*** important role of the asymptotic constant(AC)for the ^(15)N(p,γ0)16O process with interfering ^(3)s_(1)(312)and ^(3)s_(1)(962)resonances is elucidated.A comparison of our calculation for the s-factor with existing experimental and theoretical data is addressed,and a reasonable agreement is *** reaction rate is calculated and compared with the existing *** has negligible dependence on the variation of AC but shows a strong impact of the interference of ^(3)s_(1)(312)and ^(3)s_(1)(962)resonances in reference to the CNO Gamow windows,especially at low *** estimate the contribution of cascade transitions to the reaction rate based on the exclusive experimental data from ***.C.85,065810(2012).The reaction rate enhancement due to the cascade transitions is observed from T_(9)>0.3 and reaches the maximum factor~1.3 at T_(9)=*** present the Gamow energy window and a comparison of rates for radiative proton capture reactions ^(12)N(p,γ)^(13)O,^(13)N(p,γ)^(14)O,^(14)N(p,γ)^(15)O,and ^(15)N(p,γ)^(16)O obtained in the framework of the MPCM and provide the temperature windows,prevalence,and significance of each process.

关键词： low and astrophysical energies p^(15)N system thermonuclear reaction rate potential cluster model CNO-cycle

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Electroencephalogram signal Correlations between Default Mode Network and Attentional Functioning

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Journal of Behavioral and Brain science 2024年第4期14卷 119-134页

作者： Moemi Matsuo Takashi higuchi Toranosuke Abe Takuya Ishibashi Ayano Egashira Rio Kamashita Faculty of Rehabilitation sciences Nishi Kyushu University Kanzaki Japan Department of Physical Therapy Osaka University of Human Sciences Settsu Japan Research Center for Child Mental Development Chiba University Chiba Japan

Attentional issues may affect acquiring new information, task performance, and learning. Cortical network activities change during different functional brain states, including the default mode network (DMN) and attention network. We investigated the neural mechanisms underlying attentional functions and correlations between DMN connectivity and attentional function using the Trail-Making Test (TMT)-A and -B. Electroencephalography recordings were performed by placing 19 scalp electrodes per the 10 - 20 system. The mean power level was calculated for each rest and task condition. Non-parametric spearman’s rank correlation was used to examine the correlation in power levels between the rest and TMT conditions. The most significant correlations during TMT-A were observed in the high gamma wave, followed by theta and beta waves, indicating that most correlations were in the parietal lobe, followed by the frontal, central, and temporal lobes. The most significant correlations during TMT-B were observed in the beta wave, followed by the high and low gamma waves, indicating that most correlations were in the temporal lobe, followed by the parietal, frontal, and central lobes. Frontoparietal beta and gamma waves in the DMN may represent attentional functions.

关键词： Cortical Network Activities Electroencephalography Attention Default Mode Network

Enhancement of Visual Attention by Color Revealed Using Electroencephalography

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Open Journal of Therapy and Rehabilitation 2024年第1期12卷 1-9页

作者： Moemi Matsuo Takashi higuchi Takuya Ishibashi Ayano Egashira Toranosuke Abe Hiroya Miyabara Faculty of Rehabilitation sciences Nishikyushu University Kanzaki Japan Department of Physical Therapy Osaka University of Human Sciences Settsu Japan

Attention constitutes a fundamental psychological feature guiding our mental effort toward specific objects, concurrent with processes such as memory, reasoning, and imagination. Visual attention, crucial for selecting surrounding information, often decreases in older adults and patients with cerebrovascular disorders. Effective methods to enhance attention are scarce. Here, we investigated whether color information influences visual attention and brain activity during task performance, utilizing EEG. We examined 13 healthy young adults (seven women and six men;mean age: 21.2 ± 0.58 years) using 19-electrode electroencephalograms to assess the impact of color information on visual attention. The Clinical Assessment for Attention cancellation test was conducted under the black, red, and blue color conditions. Wilcoxon’s signed-rank test was used to assess differences in task performance (task time and error) between conditions. spearman’s rank correlation was utilized to examine the correlation in power levels between task performance and color conditions. significant variations in total task errors were observed among color conditions. The black condition exhibited the highest error frequency (0.7 ± 0.9 times), followed by the red condition (0.5 ± 0.8 times), with the lowest error frequency occurring in the blue (0.2 ± 0.4 times) condition (black vs. red: P = 0.03;black vs. blue: P = 0.00;red vs. blue: P = 0.032). No time difference was observed. The black condition showed negative delta and high-gamma correlations in the central electrodes. The red condition revealed positive alpha and low-gamma correlations in the frontal and occipital areas. Although no correlations were observed in the blue condition, it enhanced attentional performance. Positive alpha and low-gamma waves might be crucial for spotting attentional errors in key areas. Our findings provide insights into the effects of color information on visual attention and potential neural correlates associated

关键词： Attention Higher Brain Function Electroencephalography Neuroimaging Rehabilitation