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The 2023 M_(w)6.8 Adassil Earthquake(Chichaoua,Morocco)on a steep reverse fault in the deep crust and its geodynamic implications

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Earth and Planetary Physics 2024年第3期8卷 522-534页

作者： Billel Touati WangWang gu siDao Ni Risheng Chu Minhan sheng QingJie Xue Fouzi Bellalem said Maouche habibi Yahyaoui s.h.ol of Earth and space sciences University of Science and Technology of ChinaHefei 230026China state Key Laboratory of Geodesy and Earth’s Dynamics Innovation Academy for Precision Measurement Science and TechnologyChinese Academy of SciencesWuhan 430077China College of Earth and Planetary sciences University of Chinese Academy of SciencesBeijing 100049China Centre de Recherche en Astronomie Astrophysique et Géophysique(CRAAG)BP 63BouzaréahAlgiers 16340Algeria Geography and Territory Planning Natural Hazards and Territory Planning LaboratoryBatna 2 UniversityFesdisBatna 05000Algeria

The Mw 6.8 Adassil earthquake that occurred in the high Atlas on september 8,2023,was a catastrophic event that provided a rare opportunity to study the mechanics of deep crustal *** research aimed to decipher the rupture characteristics of the Adassil earthquake by analyzing teleseismic waveform data in conjunction with interferometric synthetic aperture radar(InsAR)observations from both ascending and descending *** analysis revealed a reverse fault mechanism with a centroid depth of approximately 28 km,exceeding the typical range for crustal *** result suggests the presence of cooler temperatures in the lower crust,which facilitates the accumulation of tectonic *** earthquake exhibited a steep reverse mechanism,dipping at 70°,accompanied by minor strike-slip *** the geotectonic framework of the high Atlas,known for its volcanic legacy and resulting thermal irregularities,we investigated the potential contributions of these factors to the initiation of the Adassil *** seismicity within the lower crust,away from plate boundaries,calls for extensive research to elucidate its implications for regional seismic hazard *** findings.h.ghlight the critical importance of studying and preparing for significant seismic events in similar geological settings,which would provide valuable insights into regional seismic hazard assessments and geodynamic paradigms.

关键词： Adassil earthquake seismogenic fault source depth interferometric synthetic aperture radar(InsAR) seismic waveform joint inversion

Neferine inhibits the progression of diabetic nephropathy by modulating the miR-17-5p/nuclear factor E2-related factor 2 axis

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Journal of Traditional Chinese Medicine 2024年第1期44卷 44-53页

作者： hUANG hongmei YANG Maojun LI Ting WANG Dandan LI Ying TANG Xiaochi YUAN Lu gu shi XU Yong Department of Endocrinology Chengdu Shuangliu District First People's Hospital(West China Airport of Sichuan University)Chengdu 610200China Department of Endocrinology Affiliated Hospital of Southwest Medical UniversityLuzhou 646000China

OBJECTIVE:To investigate the effect of Neferine(Nef)on diabetic nephropathy(DN)and to explore the mechanism of Nef in DN based on miRNA regulation ***:A DN mouse model was constructed and treated with *** creatinine(Crea),blood urea(UREA)and urinary albumin were measured in mice by kits,and renal histopathological changes and fibrosis were observed by hematoxylin-eosin staining and Masson *** tissue superoxide dismutase(sOD),malondialdehyde(MDA)and glutathione peroxidase(Gsh-Px)activities were measured by enzyme-linked immunosorbent assay(ELIsA).Western blotting was used to detect the expression of nuclear factor E2-related factor 2(Nrf2)/heme oxygenase 1(hO-1)signaling pathway-related proteins in kidney *** reverse transcription-polymerase chain reaction(q RT-PCR)was used to detect the expression of miR-17-5p in kidney ***,a DN in vitro model was constructed by high glucose culture of human mesangial cells.h.Cs),cells were transfected with miR-17-5p mimic and/or treated with Nef,and we used q RTPCR to detect cellular miR-17 expression,flow cytometry to detect apoptosis,ELIsAs to detect cellular sOD,MDA,and Gsh-Px activities,Western blots to detect Nrf2/hO-1 signaling pathway-related protein expression,and dual luciferase reporter gene assays to verify the targeting relationship between Nrf2 and ***:Administration of Nef significantly reduced the levels of blood glucose,Crea,and UREA and the expression of miR-17-5p,improved renal histopathology and fibrosis,significantly reduced MDA levels,elevated sOD and Gsh-Px activities,and activated Nrf2 expression in kidney tissues from mice with ***2 is a post-transcriptional target of *** hMCs transfected with miR-17-5p mimics,the m RNA and protein levels of Nrf2 were significantly ***,miR-17-5p overexpression and Nef intervention resulted in a significant increase in high glucose-induced apoptosis and MDA levels in hMC

关键词： diabetic nephropathies neferine miR-17-5p NF-E2-related factor 2 oxidative stress

hybrid robust fault detection and isolation of satellite reaction wheel actuators

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Journal of Control and Decision 2024年第1期11卷 117-131页

作者： h.Abbasi Nozari s.J.sadati Rostami Paolo Castaldi silvio simani Faculty of Electrical and Computer Engineering Babol Noshirvani University of TechnologyBabolIran Department of Electrical Electronic and Information EngineeringUniversity of BolognaCesenaItaly Department of Engineering University of FerraraFerraraItaly

In this paper,a combined robust fault detection and isolation s.h.me is studied for satellite system subject to actuator faults,external disturbances,and parametric *** proposed methodology incorporates a residual generation module,including a bank of filters,into an intelligent residual evaluation ***,residual filters are designed based on an improved nonlinear differential algebraic approach so that they are not affected by external *** residual evaluation module is developed based on the suggested series and parallel ***,a new ensemble classification s.h.me defined as blended learning integrates.h.terogeneous classifiers to enhance the performance.A wide range of simulations is carried out in a high-fidelity satellite simulator subject to the constant and time-varying actuator faults in the presence of disturbances,manoeuvres,uncertainties,and *** obtained results demonstrate the effectiveness of the proposed robust fault detection and isolation method compared to the traditional nonlinear differential algebraic approach.

关键词： Robust fault detection and isolation reaction wheels blended learning series and parallel fault detection and isolation forms satellite attitude control system

Ribosome-inspired electrocatalysts inducing preferential nucleation and growth of three-dimensional lithium sulfide for high-performance lithium-sulfur batteries

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Journal of Energy Chemistry 2024年第7期94卷 517-526页

作者： Zhen Wu Wenfeng he Jiahui Yang Yunuo gu Ruiqi Yang Yiran sun Jiajia Yuan Xin Wang Junwu Zhu Yongsheng Fu Key Laboratory for soft Chemistry and Functional Materials of Ministry of Education Nanjing University of Science and TechnologyNanjing 210094JiangsuChina s.h.ol of Energy and Power Engineering Jiangsu UniversityZhenjiang 212013JiangsuChina FEB Res Inst Far East BatteryWuxi 214200JiangsuChina

Nucleation of lithium sulfide(Li_(2)s)induced by electrocatalysts plays a crucial role in mitigating the shut-tle ***,short-chain polysulfides on electrocatalysts surfaces tend to re-dissolve into elec-trolytes,delaying Li_(2)s supersaturation and its *** this study,we draw inspiration from the ribosome-driven protein synthesis process in cells to prepare ultrasmall nitrogen-doped Mos_(2) nanocrys-tals anchored on porous nitrogen-doped carbon networks(N-Mos_(2)-NC)***,the ex-situ sEM demonstrates that ribosome-inspired N-Mos_(2)-NC electrocatalysts induce early nucleation and rapid growth of three-dimensional Li_(2)s during *** calculations reveal that the Li-s bond length in N-Mos_(2)-Li_(2)s(100)is shorter,and the corresponding interfacial formation energy is lower than in Mos_(2)-Li_(2)s(100).This accelerated conversion of lithium polysulfides to Li_(2)s can enhance the utilization of active substances and inhibit the shuttle *** study highlights the potential of ribosome-inspired N-Mos_(2)-NC in improving the electrochemical stability of Li-s batteries,providing valuable insights for future electrocatalyst design.

关键词： Lithium-sulfur batteries Electrocatalysts Nanocrystals Ribosome-inspired Nucleation and growth

Reducing the global cancer burden with gastrointestinal screening: China's 30 years practice

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Cancer Biology & Medicine 2024年第3期21卷 204-212页

作者： Lei Yang Li Feng Yong Zhu Ning Wang Xinpu Lu Fanghui gu Xiaotian Zhang Jiafu Ji Peking University Cancer hospital(Inner Mongolia Campus)/Affiliated Cancer hospital of Inner Mongolia Medical University Inner Mongolia Cancer CenterHohhot 010020China Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Bejing) Bejing Office for Cancer Prevention and ControlPeking University Cancer Hospital&InstituteBejing 100142China Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education) Peking University Cancer Hospital&InstituteBeijing 100142China Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Bejing) Department of Gastrointestinal OncologyPeking University Cancer Hospital&InstituteBeijing 100142China state Key Laboratory of holistic Integrative Management of Gastrointestinal Cancers Bejing Key Laboratory of Carcinogenesis and Translational ResearchGastrointestinal Cancer CenterPeking University Cancer Hospital&InstituteBeijing 100142China

Gastrointestinal(GI) cancers include esophageal [EC(International Classification of Disease 10^(th) revision: C15)], gastric [GC(C16)], and colorectal [CRC(C18-C21)] cancers. China is a high-incidence country of GI ca... 详细信息

关键词： esophageal colorectal gastrointestinal

肠镜下支架置入联合腹腔镜手术治疗结直肠癌并肠梗阻的临床效果

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中华医学杂志 2024年第28期104卷 2637-2641页

作者：谷军保杨惠鲍学斌马钊古朝阳河南省人民医院胃肠外科郑州河南省人民医院消化内科郑州

探讨肠镜下支架置入联合腹腔镜手术治疗结直肠癌并肠梗阻患者临床效果。回顾性分析2019年11月至2020年10月在河南省人民医院胃肠外科行开腹手术+术中肠腔冲洗治疗(46例, 传统组)、肠镜下支架置入+开腹手术(42例, 支架开腹组)、肠镜下支... 详细信息

探讨肠镜下支架置入联合腹腔镜手术治疗结直肠癌并肠梗阻患者临床效果。回顾性分析2019年11月至2020年10月在河南省人民医院胃肠外科行开腹手术+术中肠腔冲洗治疗(46例, 传统组)、肠镜下支架置入+开腹手术(42例, 支架开腹组)、肠镜下支架置入+腹腔镜手术(41例, 支架腹腔镜组)治疗结直肠癌并肠梗阻患者病例资料, 比较3组患者围手术期情况、生化指标、外周血癌胚抗原(CEA)、糖类抗原199(CA199)水平和预后。结果显示, 3组患者中, 支架腹腔镜组手术时间[(203.6±30.5)min]较长, 术后排气时间[(1.2±0.3)d]、住院时间[(10.5±2.1)d]较短, 术中出血量[(102.5±22.3)ml]较少(均Ps)均降低, 血小板计数(PLT)、C反应蛋白(CRP)均升高;3组患者中, 支架腹腔镜组术后EOs较支架开腹组升高, PLT、CRP均降低[EOs:(4.2±0.2)%比(3.6±0.3)%比(3.9±0.2)%;PLT:(259.6±11.4)×109/L比(294.4±11.5)×109/L比(271.7±10.7)×109/L;CRP:(8.8±2.0)比(16.4±2.2)比(14.9±2.3)ng/L;均P<0.05]。术后3个月时, 与术前相比, 3组血清CEA、CA199水平降低;3组患者中, 血清CEA、CA199水平比较差异均无统计学意义。随访3年内, 3组术后复发率、术后转移发生率比较差异均无统计学意义。本研究表明, 肠镜下支架置入联合腹腔镜手术在降低术中出血量、加快患者术后排气功能恢复、缓解患者手术应激和降低术后并发症发生率方面更具优势, 能降低患者术后血清CEA、CA199水平。

关键词：结直肠肿瘤肠梗阻支架置入腹腔镜手术癌胚抗原糖类抗原199

specifications and control of spatial frequency errors of components in two-beam laser static holographic exposure for pulse compression grating fabrication

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high Power Laser science and Engineering 2024年第1期12卷 1-12页

作者： Chen hu songlin Wan guochang Jiang haojin gu Yibin Zhang Yunxia Jin shijie Liu Chengqiang Zhao hongchao Cao Chaoyang Wei Jianda shao Precision Optical Manufacturing and Testing Center Shanghai Institute of Optics and Fine MechanicsChinese Academy of Sciences(CAS)ShanghaiChina Key Laboratory for high Power Laser Material of Chinese Academy of sciences Shanghai Institute of Optics and Fine MechanicsCASShanghaiChina Center of Materials science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijingChina hangzhou Institute for Advanced study University of Chinese Academy of SciencesHangzhouChina China-Russian Belt and Road Joint Laboratory on Laser science ShanghaiChina

The large-aperture pulse compression grating(PCG) is a critical component in generating an ultra-high-intensity, ultra-short-pulse laser;however, the size of the PCG manufactured by transmission holographic exposure is limited to large-scale high-quality materials. The reflective method is a potential way for solving the size limitation, but there is still no successful precedent due to the lack of scientific specifications and advanced processing technology of exposure mirrors. In this paper, an analytical model is developed to clarify the specifications of components, and advanced processing technology is adopted to control the spatial frequency errors. hereafter, we have successfully fabricated a multilayer dielectric grating of 200 mm × 150 mm by using an off-axis reflective exposure system with Φ300 mm. This demonstration proves that PCGs can be manufactured by using the reflection holographic exposure method and shows the potential for manufacturing the meter-level gratings used in 100 petawatt class.h.gh-power lasers.

关键词： high-power laser off-axis reflective exposure system pulse compression grating spatial frequency errors specifications

Development of a high-repetition-rate lumped-inductance kicker magnet prototype for the beam switchyard of shINE

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Nuclear science and Techniques 2024年第2期35卷 20-31页

作者： Yong-Fang Liu Rui-Ping Wang Jin Tong Bo Zhang si Chen Qi-Bing Yuan hai-Xiao Deng Ming gu Bo Liu shanghai Advanced Research Institute Chinese Academy of SciencesShanghai 201412People’s Republic of China

The shanghai high-repetition-rate X-ray free-electron laser and extreme light facility(shINE)operates at a maximum repetition rate of 1 *** magnets are key components that distribute electron bunches into three different undulator lines in a bunch-by-bunch *** kicker field width must be less than the time interval between bunches.A lumpedinductance kicker prototype was developed using a vacuum chamber with a single-turn *** full magnetic field strength was 0.005 *** paper presents the requirements,design considerations,design parameters,magnetic field calculations,and measurements of the kicker *** relevant experimental results are also *** pulse width of the magnetic field was approximately 600 ns,and the maximum operation repetition rate was 1 *** developed kicker satisfies the requirements for the shINE ***,numerous recommendations for the future optimization of kicker magnets are provided.

关键词： X-ray free-electron laser Kicker magnet Beam switchyard high repetition rate Ni-Zn ferrites

Regulate electric double layer for one-step synthesize and modulate the morphology of(oxy)hydroxides

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Nano Research 2024年第5期17卷 3675-3683页

作者： Jiaxin Liu Yue shi Yanli gu Zheng Lv Liang Zhao Yu Yang Tianrong Zhan Jianping Lai Lei Wang state Key Laboratory Base of Eco-Chemical Engineering International Science and Technology Cooperation Base of Eco-chemical Engineering and Green ManufacturingCollege of Chemistry and Molecular EngineeringQingdao University of Science and TechnologyQingdao 266042China shandong Engineering Research Center for Marine Environment Corrosion and safety Protection College of Environment and Safety EngineeringQingdao University of Science and TechnologyQingdao 266042China

FeOOh have received considerable attention due to their natural abundance and *** the significant progress achieved,the one-step synthesis of integrated FeOOh is still a major ***,the current research on FeOOh catalyst still suffers from the unclear mechanism of controlling ***,density functional theory(DFT)calculations and X-ray photoelectron spectroscopy(XPs)demonstrated the strong electron-capturing and hydrogen absorption ability of Co in FeOOh,which further promotes the formation and stabilization of *** used a one-step electrodeposition method to synthesize Co introduced FeOOh integrated electrocatalyst and propose to introduce ions with different valence states to regulate the morphology of FeOOh by precise modulation of electric double layer(EDL)composition and *** prepared Co-FeOOh-K^(+)has a larger electrochemically active surface area(ECsA)(325 cm^(2))and turnover frequency(TOF)value(0.75 s^(-1)).In the electrochemical experiments of an alkaline anion exchange membrane electrolyzer,Co-FeOOh-K^(+)shows better oxygen evolution performance than commercial RuO_(2) under industrial production conditions and has good industrial application prospects.

关键词： integrated(oxy)hydroxides electrodeposition electric double layer(EDL) oxygen evolution reaction(OER) morphology regulation