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EventLFM:event camera integrated Fourier light field microscopy for ultrafast 3D imaging

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Light(science & Applications) 2024年第7期13卷 1401-1415页

作者： Ruipeng Guo Qianwan Yang Andrew s.chang Guorong Hu Joseph Greene Christopher V.Gabel sixian You Lei Tian Department of Electrical and Computer Engineering Boston UniversityBostonMA 02215USA Department of Physiology and Biophysics Boston UniversityBostonMA 02215USA. Neurophotonics Center Boston UniversityBostonMA 02215USA. Research Laboratory of Electronics(RLE)in the Department of Electrical science and Engineering Massachusetts Institute of TechnologyCambridgeMA 02139USA. Department of Biomedical Engineering Boston UniversityBostonMA 02215USA

Ultrafast 3D imaging is indispensable for visualizing complex and dynamic biological *** scanning-based techniques necessitate an inherent trade-off between acquisition speed and space-bandwidth product(sBP).Emerging single-shot 3D wide-field techniques offer a promising alternative but are bottlenecked by the synchronous readout constraints of conventional CMOs systems,thus restricting data throughput to maintain high sBP at limited frame *** address this,we introduce EventLFM,a straightforward and cost-effective system that overcomes these challenges by integrating an event camera with Fourier light field microscopy(LFM),a state-of-theart single-shot 3D wide-field imaging *** event camera operates on a novel asynchronous readout architecture,thereby bypassing the frame rate limitations inherent to conventional CMOs *** further develop a simple and robust event-driven LFM reconstruction algorithm that can reliably reconstruct 3D dynamics from the unique spatiotemporal measurements captured by *** results demonstrate that EventLFM can robustly reconstruct fast-moving and rapidly blinking 3D fluorescent samples at kHz frame ***,we highlight EventLFM’s capability for imaging of blinking neuronal signals in scattering mouse brain tissues and 3D tracking of GFP-labeled neurons in freely moving *** believe that the combined ultrafast speed and large 3D sBP offered by EventLFM may open up new possibilities across many biomedical applications.

关键词： field linking overcome

Modeling for critical state line of granular soil with evolution of grain size distribution due to particle breakage

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Geoscience Frontiers 2020年第2期11卷 473-486页

作者： Ching s.chang Yibing Deng Department of Civil and Environmental Engineering University of Massachusetts

Determination of the critical state line(CsL)is important to characterize engineering properties of granular *** size distribution(GsD)has a significant influence on the location of *** influence of particle breakage on the CsL is mainly attributed to the change in GsD due to particle ***,GsD has not been properly considered in modeling the CsL with influence of particle *** study aims to propose a quantitative model to determine the CsL considering the effect of *** hypothesize that the change of critical state void ratio with respect to GsD is caused by the same mechanism that influences of the change of minimum void ratio with respect to ***,the particle packing model for minimum void ratio proposed by chang et al.(2017)is extended to predict critical state void *** developed model is validated by experimental results of CsLs for several types of granular *** the evolution of GsD due to particle breakage is incorporated into the *** model is further evaluated using the experimental results on rockfill material,which illustrates the applicability of the model in predicting CsL for granular material with particle breakage.

关键词： Critical state void ratio Particle breakage Grain size distribution Particle packing model Granular material

Numerical study on Dry Deposition Processes in Canopy Layer

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Advances in Atmospheric sciences 1992年第4期9卷 491-500页

作者：雷孝恩 Julius s.chang Institute of Atmospheric Physics Academia Sinica Beijing AsRC State University of New York Albany N.Y. 12205 U.S.A. coupling model between the canopy layer(CL) and atmospheric boundary layer (ABL) for the study of dry deposition velocity is developed. The model consists of six parts: chemical species conservation equation including absorptive factor the species uptake action including detailed vertical variation of absorptive element in CL momentum exchange in CL which is represented by a first-order closure momentum equation with an additional larger-scale diffusive term momentum exchange in ABL which is described by a complete set of the ABL turbulent statistic parameters absorptivity (or solubility or reflection) at the surface including effects of the physical and chemical characters of the species land type seasonal and diurnal variations of the meteorological variables and deposition velocity derived by distributions of the species with height in CL. Variational rules of the concentration and deposition velocity with both height and time are simulated with the model for both corn and forest canopies. Results predicted with the bulk deposition velocity derived in the paper consist well with experimental data.

A coupling model between the canopy layer(CL) and atmospheric boundary layer (ABL) for the study of dry deposition velocity is developed. The model consists of six parts: chemical species conservation equation including absorptive factor; the species uptake action including detailed vertical variation of absorptive element in CL; momentum exchange in CL which is represented by a first-order closure momentum equation with an additional larger-scale diffusive term; momentum exchange in ABL which is described by a complete set of the ABL turbulent statistic parameters; absorptivity (or solubility or reflection) at the surface including effects of the physical and chemical characters of the species, land type, seasonal and diurnal variations of the meteorological variables; and deposition velocity derived by distributions of the species with height in CL. Variational rules of the concentration and deposition velocity with both height and time are simulated with the model for both corn and forest canopies. Results predicted with the bulk deposition velocity derived in the paper consist well with experimental data.

关键词： Numerical study on Dry Deposition Processes in Canopy Layer

Nanoscale plasma-activated aerosol generation for in situ surface pathogen disinfection

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Microsystems & Nanoengineering 2022年第2期8卷 161-173页

作者： Nicholas s.L.Chew Kiing s.Wong Wei s.chang Chien W.Ooi Leslie Y.Yeo Ming K.Tan Mechanical Engineering Discipline School of EngineeringMonash University MalaysiaBandar SunwaySelangorMalaysia Chemical Engineering Discipline School of EngineeringMonash University MalaysiaBandar SunwaySelangorMalaysia Micro/Nanophysics Research Laboratory RMIT UniversityMelbourneVICAustralia

Plasma treatment constitutes an efficient method for chemical-free disinfection.A spray-based system for dispensing plasma-activated aerosols onto surfaces would facilitate disinfection of complex and/or hidden surfaces inaccessible to direct line-of-sight(for example,UV)*** complexity and size of current plasma generators(for example,plasma jet and cometary plasma systems)-which prohibit portable operation,together with the short plasma lifetimes,necessitate a miniaturized in situ technique in which a source can be simultaneously activated and administered on-demand onto ***,we demonstrate this possibility by combining two nanoscale technologies for plasma and aerosol generation into an integrated device that is sufficiently small and *** is generated on a carpet of zinc oxide nanorods comprising a nanoneedle ensemble,which when raised to a high electric potential,constitutes a massive point charge array with near-singular electric fields to effect atmospheric *** plasma is then used to activate water transported through an underlying capillary wick,that is subsequently aerosolized under MHz-order surface acoustic *** show that the system,besides being amenable to miniaturization and hence integration into a chipscale device,leads to a considerable improvement in plasma-activation over its macroscale cometary discharge predecessor,with up to 20%and 127%higher hydrogen peroxide and nitrite ion concentrations that are respectively generated in the plasma-activated ***,in turn,leads to a 67%reduction in the disinfection time to achieve 95%bacterial load reduction,therefore demonstrating the potential of the technology as an efficient portable platform for on-demand field-use surface disinfection.

关键词： surface portable aerosol

Hydrogen yields of three typical acidogenesis fermentation communities in anaerobic activated sludge process

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Hydrogen yields of three typical acidogenesis fermentation c...

利用Thermo scientific全新高分辨台式、四极杆静电场轨道阱Q-Exactive分析19种β-受体激动剂

第九届全国氢能学术会议

作者： J.Z.Li,G.C.Zheng,J.G.He,s.chang,Z.Qin Harbin Institute of Technology,China

＜正＞More and more interest has concentrated on biohydrogen production by anaerobic activated sludge fermentation *** anaerobic activated sludge is mixed microbial community containing diverse *** types of fermentati...

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中国食品 2011年第18期 62-65页

作者：叶芳挺王勇为 James s.chang 赛默飞世尔科技(中国)有限公司

β-受体激动剂．又称为β-兴奋剂，大家近期所熟知的瘦肉精一克伦特罗．莱克多巴胺等就是这一类兴奋剂。其是一类含氮激素中的苯乙胺类药物，苯乙胺类药物具有苯乙醇胺结构母核．苯环上连接有碱性的β-羟胺侧链。由于发现在饲料中添加β-

关键词：受体激动剂高分辨静电场四极杆 β-兴奋剂利用台式轨道

Metabolic pathways of hydrogen evolution in fermentative acidogenic microflora

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Metabolic pathways of hydrogen evolution in fermentative aci...

基于双源CT单能量成像技术在心肌病病人心肌延迟强化评估中的应用

第九届全国氢能学术会议

作者： J.G.He,L.G.Zhang,J.Z.Li,s.chang,Z.Qin Harbin Institute of Technology,China

＜正＞Hydrogen production by anaerobic activated sludge fermentation process has attracted more and more attention all around world and been extensively *** a continuous stirred-tank reactor（CsTR） system in pilot-scale has been established and the hydrogen yield of a specifically acclimated fermentative acidogenic microbial community has been

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国际医学放射学杂志 2018年第4期 469-470页

作者： s.chang K.Han J.C.Youn D.J.Im J.Y.Kim Y.J.suh 王诗渝 Department of Radiology Research Institute of Radiological ScienceSeverance HospitalYonsei University College of Medicine

目的探讨基于双源CT单能量成像技术在心肌病病人心肌延迟强化评估中的应用价值。材料与方法这项前瞻性研究经所在机构伦理委员会批准,所有入组病人均签署了知情同意书。40例心肌病病人[男27例,女13例,年龄22;1岁,平均（56±15）岁]接受... 详细信息

目的探讨基于双源CT单能量成像技术在心肌病病人心肌延迟强化评估中的应用价值。材料与方法这项前瞻性研究经所在机构伦理委员会批准,所有入组病人均签署了知情同意书。40例心肌病病人[男27例,女13例,年龄22;1岁,平均（56±15）岁]接受了心脏MRI和双源CT检查。对双源CT数据采用常规（120 k V）和单能量（60 ke V、70 ke V和80 ke V）重建,得到4组影像。采用Friedman配对检验比较多组影像间的主观质量评分、对比噪声比（CNR）和硬化束伪影。以心脏MR成像结果为参考标准,利用logistic回归分析评估双源CT延迟强化的诊断效能和对心肌病分类的预测能力。使用Bland-Altman方法评估心脏MRI和CT延迟强化之间的一致性。结果与传统CT相比,70 ke V单能量CT影像的主观质量（平均分,3.38±0.54和3.15±0.43;P=0.006 7）和CNR（平均值4.26±1.38和3.93±1.33;P=0.004 7）更高,硬化束伪影更低（平均值3.47±1.56和4.15±1.67;P=0.000 1）。与常规CT相比,70 ke V单能量CT影像延迟强化的诊断效能更高[敏感度,94.6%∶90.4%（P=0.003 2）;特异度,96.0%∶94.0%（P=0.0031）;准确度,95.6%∶92.7%（P=0.000 1）],同时对心肌病分类的预测能力也更高[心内膜下型,91.5%∶84.3%（P=0.011 1）;心外膜型,94.3%∶73.5%（P=0.000 1）;透壁型,93.0%∶77.7%（P=0.001 8）;心肌间质型,85.4%∶69.2%（P=0.004 7）;斑片状型,84.4%∶78.4%（P=0.151 4）]。对于延迟强化的定量评估,70 ke V单能量CT影像显示的偏差更小（0.153 4%,95%的一致性限度:-4.701 3～5.008 0）。结论与传统CT影像相比,基于双源CT的70 ke V单能量影像的延迟强化技术能够通过提高影像质量和CNR,以及减少光束硬化伪影来改善对心肌病的评估。

关键词：心肌病单能量成像 CT

Validation of COsMIC ionospheric peak parameters by the measurements of an ionosonde chain in China

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Validation of COSMIC ionospheric peak parameters by the meas...