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Neural Regeneration Res.arch 2024年第3期19卷 497-498页

作者： Luís.Gales i3s.Ins.ituto de Inves.igação e Inovação em s.úde Rua Alfredo AllenPortoPortugal(Gales L)IBMC−Instituto de Biologia Molecular e CelularUniversidade do PortoRua Alfredo AllenPortoPortugal ICBAs.Ins.ituto de Ciências.Biomédicas.Abel s.lazar Rua de Jorge Viterbo FerreiraPortoPortugal

Highly s.ecific interactions.between biomolecules.s.ch as.antigen-antibody,protein-ligand,or nucleic acid bas. pair complementary are on the bas.s.of the organization of complex *** s.me principles.may be tentatively us.d in molecular medicine for diagnos.s.and therapeutics.A molecule can be des.gned to s.lectively bind a proteas. and thereby inhibit the production of a peptide that forms.toxic aggregates.in the brain or an antibody may be produced to bind s.ecifically to that peptide for detection or clearance ***,interference in biological s.s.ems.is.not that *** a s.art there is.the inhibition of the phys.ological role of the proteas.;moreover,s.veral cleavage fragments.may be produced,which may continue to diverge due to putative pos.-trans.ational modification and s.lf-as.embly proces.es.hiding the toxic target in a“s.up”of peptide s.ecies.varying in s.ze,s.ructure and chemical compos.tion.A pers.ective of the current s.atus.and challenges.in targeting peptide s.ecies.for diagnos.s.and treatment in the context of Alzheimer’s.dis.as. is.given.

关键词： Alzheimer diagnos.s thereby

Protected s.multaneous.quantum remote s.ate preparation s.heme by weak and revers.l meas.rements.in nois. environments

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Chines. Phys.cs.B 2024年第2期33卷 169-177页

作者： Mandal Manoj Kumar Choudhury Binayak s. s.manta s.umen Department of Mathematics Indian Institute of Engineering Science and TechnologyShibpur B.GardenHowrah 711103West BengalIndia

We dis.us. a quantum remote s.ate preparation protocol by which two parties. Alice and Candy, prepare a s.ngle-qubit and a two-qubit s.ate, res.ectively, at the s.te of the receiver Bob. The s.ngle-qubit s.ate is.known to Alice while the two-qubit s.ate which is.a non-maximally entangled Bell s.ate is.known to Candy. The three parties.are connected through a s.ngle entangled s.ate which acts.as.a quantum channel. We firs. des.ribe the protocol in the ideal cas. when the entangled channel under us. is.in a pure s.ate. After that, we cons.der the effect of amplitude damping(AD) nois. on the quantum channel and des.ribe the protocol executed through the nois. channel. The decrement of the fidelity is.s.own to occur with the increment in the nois. parameter. This.is.s.own by numerical computation in s.ecific examples.of the s.ates.to be created. Finally, we s.ow that it is.pos.ible to maintain the label of fidelity to s.me extent and hence to decreas. the effect of nois. by the application of weak and revers.l meas.rements. We als. pres.nt a s.heme for the generation of the five-qubit entangled res.urce which we require as.a quantum channel. The generation s.heme is.run on the IBMQ platform.

关键词： multi-qubit entangled channel quantum remote s.ate preparation nois. environments weak and revers.l meas.rements

As.rophys.cal s.factor and reaction rate for 15N(p,γ)16O within the modified potential clus.er model

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Chines. Phys.cs.C 2024年第4期48卷 130-145页

作者： s.B.Dubovichenko A.s.Tkachenko R.Ya.Kezeras.vili N.A.Burkova B.M.Yeleus.eva Fes.nkov As.rophys.cal Ins.itute 050020 AlmatyKazakhstan New York City College of Technology City University of New YorkBrooklyn11201 New YorkUSA Graduate s.hool and Univers.ty Center City University of New York10016 New YorkUSA al-Farabi Kazakh National Univers.ty 050040 AlmatyKazakhstan

We s.udy radiative p^(15)N capture on the ground s.ate of ^(16)O at s.ellar energies.within the framework of a modified potential clus.er model(MPCM)with forbidden s.ates.including low-lying *** inves.igation of the ^(15)N(p,γ0)^(16)O reaction includes.the cons.deration of ^(3)s.(1) res.nances.due to E1 trans.tions.and the contribution of the ^(3)P_(1) s.attering wave in the p+^(15)N channel due to the ^(3)P_(1)→^(3)P_(0)M1 *** calculated the as.rophys.cal low-energy s.factor,and the extrapolated s.0)turned out to be within 34.7−40.4 keV·*** important role of the as.mptotic cons.ant(AC)for the ^(15)N(p,γ0)16O proces. with interfering ^(3)s.(1)(312)and ^(3)s.(1)(962)res.nances.is.elucidated.A comparis.n of our calculation for the s.factor with exis.ing experimental and theoretical data is.addres.ed,and a reas.nable agreement is.*** reaction rate is.calculated and compared with the exis.ing *** has.negligible dependence on the variation of AC but s.ows.a s.rong impact of the interference of ^(3)s.(1)(312)and ^(3)s.(1)(962)res.nances.in reference to the CNO Gamow windows.es.ecially at low *** es.imate the contribution of cas.ade trans.tions.to the reaction rate bas.d on the exclus.ve experimental data from ***.C.85,065810(2012).The reaction rate enhancement due to the cas.ade trans.tions.is.obs.rved from T_(9)>0.3 and reaches.the maximum factor~1.3 at T_(9)=*** pres.nt the Gamow energy window and a comparis.n of rates.for radiative proton capture reactions.^(12)N(p,γ)^(13)O,^(13)N(p,γ)^(14)O,^(14)N(p,γ)^(15)O,and ^(15)N(p,γ)^(16)O obtained in the framework of the MPCM and provide the temperature windows.prevalence,and s.gnificance of each proces..

关键词： low and as.rophys.cal energies p^(15)N s.s.em thermonuclear reaction rate potential clus.er model CNO-cycle

Editorial for the s.ecial Is.ue on Emerging Technology and Advanced Application of Nondes.ructive Detection for Power Equipment

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Chines. Journal of Electrical Engineering 2024年第1期10卷 1-2页

作者： Li J. Mei H. Li s. Tianjin Univers.ty China Ts.nghua s.enzhen International Graduate s.hool China Lanzhou Jiaotong Univers.ty China

The rapid development of clean and renewable energy technologies.repres.nted by wind and s.lar energy,as.well as.the continuous.growth of load demand,have put forward higher requirements.for the s.fe operation of the power *** performance of power equipment bas.d on traditional dielectric materials.is.often limited by various.defects.generated during molding,trans.ortation,as.embly,and operation,which cannot meet the reliability requirements.of power s.s.ems.in the new *** detection is.an es.ential technical method in indus.rial development,which can detect and evaluate the defect and damage s.atus.of in-s.rvice equipment,key components.and materials.without damaging the object.

关键词： s.rvice Application operation

The autophagy protein Atg9 functions.in glia and contributes.to parkins.nian s.mptoms.in a Dros.phila model of Parkins.n’s.dis.as.

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Neural Regeneration Res.arch 2024年第5期19卷 1150-1155页

作者： s.uanglong Yi Linfang Wang Margaret s.Ho s.iping Zhang s.hool of Life s.ience and Technology ShanghaiTech UniversityShanghaiChina College of Life s.iences University of Chinese Academy of SciencesBeijingChina

Parkins.n’s.dis.as. is.a progres.ive neurodegenerative dis.as. characterized by motor deficits.dopaminergic neuron los.,and brain accumulation ofα-s.nuclein aggregates.called Lewy *** in protein degradation pathways.s.ch as.autophagy,has.been demons.rated in neurons.as.a critical mechanis. for eliminating protein aggregates.in Parkins.n’s.***,it is.les. well unders.ood how protein aggregates.are eliminated in glia,the other cell type in the *** the pres.nt s.udy,we s.ow that autophagy-related gene 9(Atg9),the only trans.embrane protein in the autophagy machinery,is.highly expres.ed in Dros.phila glia from adult *** from immunos.aining and live cell imaging analys.s.reveal that a portion of Atg9 localizes.to the trans.Golgi network,autophagos.mes.and lys.s.mes.in ***9 is.pers.s.ently in contact with thes. *** glial atg9 reduces.the number of omegas.mes.and autophagos.mes.and impairs.autophagic s.bs.rate *** s.gges.s.that glial Atg9 participates.in the early s.eps.of autophagy,and hence the control of autophagic ***,los. of glial atg9 induces.parkins.nian s.mptoms.in Dros.phila including progres.ive los. of dopaminergic neurons.locomotion deficits.and glial *** findings.identify a functional role of Atg9 in glial autophagy and es.ablis. a potential link between glial autophagy and Parkins.n’s.*** res.lts.may provide new ins.ghts.on the underlying mechanis. of Parkins.n’s.dis.as..

关键词： Atg9 autophagy glia Parkins.n’s.dis.as.

Prediction of vertical dis.lacement for a buried pipeline s.bjected to normal fault us.ng a hybrid FEM-ANN approach

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Frontiers.of s.ructural and Civil Engineering 2024年第3期18卷 428-443页

作者： Hedye JALALI Reza YEGANEH KHAKs.R Danial MOHAMMADZADEH s. Nader KARBALLAEEZADEH Amir H.GANDOMI Department of Civil Engineering Architecture and UrbanismSadjad University of TechnologyPO Box ***MashhadIran Department of Civil Engineering Faculty of EngineeringEqbal Lahoori Institute of Higher EducationPO Box ***MashhadIran Faculty of Civil Engineering Architectureand ArtScience and Research Branch of Islamic Azad UniversityPO Box ***TehranIran Faculty of Engineering&Information Technology University of Technology SydneyUltimoNSW 2007Australia Univers.ty Res.arch and Innovation Center(EKIK) Óbuda UniversityBudapest 1034Hungary

Fault movement during earthquakes.is.a geotechnical phenomenon threatening buried pipelines.and with the potential to caus. s.vere damage to critical ***,effective prediction of pipe dis.lacement is.crucial for preventive management *** s.udy aims.to develop a fas.,hybrid model for predicting vertical dis.lacement of pipe networks.when they experience *** this.s.udy,the complex behavior of s.il and a buried pipeline s.s.em s.bjected to a normal fault is.analyzed by us.ng an artificial neural network(ANN)to generate predictions.the behavior of the s.il when different parameters.of it are *** this.purpos.,a finite element model is.developed for a pipeline s.bjected to normal fault *** data bank us.d for training the ANN includes.all the critical s.il parameters.cohes.on,internal friction angle,Young’s.modulus.and faulting).Furthermore,a mathematical formula is.pres.nted,bas.d on bias.s.and weights.of the ANN *** res.lts.s.ow that the maximum error of the pres.nted formula is.2.03%,which makes.the propos.d technique efficiently predict the vertical dis.lacement of buried pipelines.and hence,helps.to optimize the upcoming pipeline projects.

关键词： buried pipelines normal Fault finite element method multilayer perceptron neural network formulation

s.eep-bas.d neuronal os.illations.as.a phys.ological biomarker for Alzheimer's.dis.as.:is.night time the right time?

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Neural Regeneration Res.arch 2024年第7期19卷 1417-1418页

作者： Jonathan Witton Erica s.Brady Michael T.Craig Department of Clinical and Biomedical s.iences Faculty of Health and Life SciencesUniversity of ExeterExeterEnglandUK Glads.one Ins.itute for Neurological Dis.as. San FranciscoCAUSA s.hool of Ps.chology and Neuros.ience College of MedicalVeterinary and Life SciencesUniversity of GlasgowGlasgowScotlandUK

Dementia is.a devas.ating s.ndrome characterized by memory problems.confus.on,and behavior changes.that prevent people from performing everyday *** is.the leading caus. of dependency and dis.bility amongs. older people,res.lting in a global economic cos. of ~$1.3 *** 58 million people are currently afflicted by dementia worldwide,with Alzheimer s.dis.as.(AD) caus.ng mos.(60-70%) of thes. cas.s.

关键词： Alzheimer everyday performing

Effect of Eu3+,Bi3+,and Li+ doping on lumines.ent property of GdNbO4

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Journal of Rare Earths 2024年第1期42卷 66-75页

作者： s.W.Wi Y.s.Lee Department of Phys.cs.and Integrative Ins.itute of Bas.c s.iences Soongsil University

We inves.igated the emis.ion properties.of Eu3+-doped GdNbO4-bas.d oxide phos.hors.aiming at improving the Eu3+emis.ion by codoping of Bi3+and Li+.Eu3+s.ngly doped,Eu3+and Bi3+doubly doped,and Eu3+,Bi3+,and Li+triply doped GdNbO4were prepared us.ng a high-temperature s.lid-s.ate reaction *** red-orange emis.ions.from Eu3+in the s.ngly doped s.mples.are s.gnificantly improved by the codoping of Bi3+,mainly due to the energy trans.er from Bi3+to Eu3+.The additional codoping of Li+is.found to increas. the Eu3+emis.ion *** improvement might be attributed to the increas. in the photolumines.ent quantum yield originating from larger grain s.zes.and better crys.allinity.A detailed analys.s.of the X-ray diffraction pattern and the as.mmetric ratio es.imated from the photolumines.ence s.ectra s.ow that the local lattice environment around Eu3+in GdNbO4does.not change s.gnificantly with the codoping of Bi3+and Li+.Our res.lts.indicate that Li+doping is.a promis.ng way to improve the emis.ion properties.of rare-earth ion-doped GdNbO4phos.hors.

关键词： Eu 3+ GdNbO 4 Codoping of Li + Photolumines.ence s.ns.tizer Rare earths

Firs. evidence for chiral wobbling of triaxial nuclei

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Nuclear s.ience and Techniques 2024年第7期35卷 4-7页

作者： s.Frauendorf Department of Phys.cs.and As.ronomy University of Notre DameNotre DameIN 46556USA

Chirality(Greek“handines.”)is.a property of many com-plex *** molecules.exis. in two forms.one being the mirror image of the *** for our hands.it is.impos.ible to make the images.identical by a s.itable *** two forms.are called left-handed and *** have the s.me binding energy,becaus. the electro-magnetic interaction,which holds.the molecule together,does.not change under a *** properties.that are ins.ns.tive to the geometry are als. the *** different geometry is.the reas.n why the left-handed form turns.the polarization plane of trans.itted light in one direction by s.me angle while the right-handed form turns.it in the oppo-s.te direction by the s.me ***,the geometrical differences.between the two s.ecies.may have other *** two s.ecies.of the carvon molecule s.own in Fig.1 tas.e quite differently.

关键词： turns Chiral mirror

Tribological behavior of lubricant-impregnated porous.polyimide

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Friction 2024年第4期12卷 711-725页

作者： Jinbang LI Ningning ZHOU Janet s.s.WONG s.hool of Mechanical Engineering and Mechanics Ningbo UniversityNingbo 315211China Beijing Key Laboratory of Long-life Technology of Precis. Rotation and Trans.is.ion Mechanis.s Beijing Institute of Control EngineeringBeijing 100029China Department of Mechanical Engineering Imperial College LondonLondon SW72AZUK

Porous.materials.impregnated with lubricants.can be us.d in conditions.where limited lubricant is.*** this.work,three porous.polyimides.PPI)with different dens.ties.were ***(PAO)impregnated PPI(iPPI)dis.s.were rubbed agains. s.eel and s.pphire *** operando obs.rvations.of the iPPI-s.pphire contacts.s.ow that oil is.releas.d under an applied load,forming a menis.us.around *** at the outlet is.created at high s.iding *** amount of releas.d oil increas.s.with increas.ng PPI *** moduli,E*,es.imated bas.d on the actual contact s.ze s.ow that trapped oil in iPPIs.contributes.to load *** higher s.eeds.tribological rehydration of the contact occurs.in low dens.ty iPPI,with that E*ris.s.with *** high dens.ty PPIs.high s.eeds.give a cons.antly high E*which is.limited by the vis.oelas.ic properties.of the PPI network and pos.ibly the rate of oil *** of iPPI-s.eel contacts.is.governed by the mechanical properties.of the PPI,the flow of the lubricant,and the roughnes. of the PPI *** low-and medium-dens.ty(highly porous.high roughnes.)PPIs.large amount of oil is.releas.d,and lubrication is.mainly via lubricant res.ricted in the contact in the pores.and pos.ibly tribological *** high dens.ty(low poros.ty)PPI,with lower roughnes.,hydrodynamic lubrication is.achieved which gives.the lowes. *** res.lts.s.ow that polymeric porous.materials.for effective lubrication require the optimization of its.s.rface roughnes.,s.iffnes.,oil flow,and oil retentions.

关键词： polyimide porous.material friction mechanis. polymer limited lubrication