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Brain-derived neurotrophic factor s.g.aling.in the neurom.s.ular junction during.developm.ntal axonal com.etition and s.naps. elim.nation

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Neural Reg.neration Res.arch 2025年第2期20卷 394-401页

作者： Jos.p Tom.s.Víctor Cilleros.m.ñé Laia Jus.-Borràs.m.rta Balanyà-s.g.ra Alek.0}ndra Polis.chuk.Laura Nadal m.rta Tom.s.Carolina s.lvera-s.m.n m.nel m.s.ntafé m.ria A.Lanuza Unitat d’His.olog.a i Neurobiolog.a(UHNeurob) Facultat de Medicina i Ciències de la SalutUniversitat Rovira i VirgiliReusSpain

During.the developm.nt of the nervous.s.s.em.there is.an overproduction of neurons.and *** com.etition between neig.boring.nerve ending.1}and s.naps.s.perform.ng.different activity levels.leads.to their elim.nation or *** have extens.vely s.udied the involvem.nt of the brain-derived neurotrophic factor-Tropom.os.n-related k.nas. B receptor neurotrophic retrog.ade pathway,at the neurom.s.ular junction,in the axonal developm.nt and s.naps. elim.nation proces. vers.s.the s.naps. *** purpos. of this.review is.to des.ribe the neurotrophic influence on developm.ntal s.naps. elim.nation,in relation to other m.lecular pathways.that we and others.have found to reg.late this.*** particular,we s.m.arize our publis.ed res.lts.bas.d on trans.itter releas. analys.s.and axonal counts.to s.ow the different involvem.nt of the pres.naptic acetylcholine m.s.arinic autoreceptors.coupled to downs.ream.s.rine-threonine protein k.nas.s.A and C(Pk. and Pk.)and voltag.-g.ted calcium.channels.at different nerve ending.1}in developm.ntal *** dynam.c chang.s.that occur s.m.ltaneous.y in s.veral nerve term.nals.and s.naps.s.converg. acros. a pos.s.naptic s.te,influence each other,and require careful s.udies.to individualize the m.chanis.s.of s.ecific *** des.ribe an activity-dependent balance(related to the extent of trans.itter releas.)between the pres.naptic m.s.arinic s.btypes.and the neurotrophin-m.diated Trk./p75NTR pathways.that can influence the tim.ng.and fate of the com.etitive interactions.between the different axon *** downs.ream.dis.lacem.nt of the Pk./Pk. activity ratio to lower values.both in com.eting.nerve term.nals.and at pos.s.naptic s.tes.plays.a relevant role in controlling.the elim.nation of s.pernum.rary ***,calcium.entry throug. L-and P/Q-s.btypes.of voltag.-g.ted calcium.channels.both channels.are pres.nt,tog.ther with the N-type channel in developing.nerve term.nals.contributes.to red

关键词： acetylcholine releas. adenos.ne receptors axonal com.etition brain-derived neurotrophic factor calcium.channels m.tor end-plate m.s.arinic acetylcholine receptors pos.natal s.naps. elim.nation s.rine k.nas.s tropom.os.n-related k.nas. receptorB

Predicting.m.xim.m.Lifes.an Lim.ts.at m.an m.nopaus.l Ag.

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Journal of m.them.tical Res.arch with Applications 2025年第1期 133-142页

作者： m.s.m.THI s.ANTONY CARLA Departm.nt of m.them.tics N.M.S.S.Vellaichamy Nadar College Res.arch s.holar (Part-tim.) Madurai Kamaraj University

The ag. at which a wom.n enters.natural m.nopaus. has.als. been as.ociated to death from.any caus.. m.nopaus. is.a natural com.onent of ag.ng.that happens.between the ag.s.of 45 and 55, with the averag. m.nopaus.l ag. being.51. Previous.res.arch has.revealed the ag. at which wom.n reach m.nopaus., but there is.no evidence to s.pport the link.between m.nopaus. and long.vity. We m.de a s.udy in as.es.ing.the lim.ts.of m.xim.m.lifes.an at m.nopaus.l ag. in our previous.article. In this.paper, we aim.to predict the m.xim.m.lifes.an of wom.n at m.an m.nopaus.l ag..

关键词：

g.aphite-lik. and Diam.nd-lik. Carbon Coating.3}with Exceptional Tribolog.cal Properties

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材料热处理学报 2004年第05B期25卷 796-802页

作者： m. Jarratt s. k. Field D.g. Teer Teer Coating.0}Ltd. West Stone House West Stone Berry Hill Industrial Estate Droitwich WR9 9AS UKTeer Coatings Ltd. West Stone House West Stone Berry Hill Industrial Estate Droitwich WR9 9AS UKTeer Coatings Ltd. West Stone House West Stone Berry Hill Industrial Estate Droitwich WR9 9AS UK

Two hard, carbon-bas.d s.lid lubricant coating.0} g.aphit-iC? and Dym.n-iC?, have been developed that offer cons.derable benefits.for indus.ry. Both of thes. new coating.0}have a hig. tribolog.cal load-bearing.capacity, exceptional wear res.s.ance and very low friction, even in dry or lubricant-s.arved contact. This.is.in contras. to m.ny com.ercial diam.nd-lik. carbon, DLC coating.0} which tend to be hig.ly s.res.ed and therefore brittle, m.k.ng.them.uns.itable for hig. load bearing.indus.rial applications. The developm.nt of the new s.lid lubricant coating.0}is.des.ribed, and details.of their tribolog.cal perform.nce in dry, water and oil-lubricated environm.nts.are g.ven. The s.ructure of the coating.0}has.been inves.ig.ted and related to the tribolog.cal properties. and the m.chanis. for the low friction and wear rates.is.dis.us.ed. The coating.0}have been us.d to s.cces.fully im.rove the lifetim. and efficiency of m.ny hig.ly loaded m.chanical parts. including.autom.tive fuel injection com.onents. g.ars. bearing.0} tappets.(cam.followers., g.dg.on (wris.) pins. etc. They als. offer benefits.for tooling.and are widely us.d in form.ng.or m.chining.of non-ferrous.alloys. and extens.vely on dies.and m.ulds. Other indus.rial application areas.include electrical devices.that require either hig. conductivity or ins.lation, optical devices.requiring.abras.on res.s.ance and s.rg.cal tools.and im.lants.

关键词： DLC 摩擦力碳覆层固体润滑剂

s.lution‑Proces.ed Thin Film.Trans.arent Photovoltaics.Pres.nt Challeng.s.and Future Developm.nt

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Nano-m.cro Letters 2025年第2期17卷 566-600页

作者： Tianle Liu m.nerah m.s.Alm.tairi Jie m. Ais.ing.s.ewart Zhaohui Xing.m.ng.ia Liu Bo Hou Yuljae Cho Um.s.TU Joint Ins.itute Shanghai Jiao Tong UniversityShanghai 200240People’s Republic of China s.hool of Phys.cs.and As.ronom. Cardiff UniversityCardiff CF243AAWalesUK Departm.nt of Electrical and Com.uter Eng.neering Yale UniversityNew HavenCT 06511USA Energ. s.iences.Ins.itute Yale UniversityWest HavenCT 06516USA Future Photovoltaics.Res.arch Center Global Institute of Future TechnologyShanghai Jiao Tong UniversityShanghai 200240People’s Republic of China

Electrical energ. is.es.ential for m.dern s.ciety to s.s.ain econom.c *** s.aring.dem.nd for the electrical energ.,tog.ther with an awarenes. of the environm.ntal im.act of fos.il fuels.has.been driving.a s.ift towards.the utilization of s.lar ***,traditional s.lar energ. s.lutions.often require extens.ve s.aces.for a panel ins.allation,lim.ting.their practicality in a dens. urban *** overcom. the s.atial cons.raint,res.archers.have developed trans.arent photovoltaics.TPV),enabling.windows.and facades.in vehicles.and building.0}to g.nerate electric *** TPV advancem.nts.are focus.d on im.roving.both trans.arency and power output to rival com.ercially available s.licon s.lar *** this.review,we firs. briefly introduce waveleng.h-and non-waveleng.hs.lective s.rateg.es.to achieve *** of m.rit and theoretical lim.ts.of TPVs.are dis.us.ed to com.rehens.vely unders.and the s.atus.of current TPV *** we hig.lig.t recent prog.es. in different types.of TPVs.with a particular focus.on s.lution-proces.ed thin-film.photovoltaics.PVs.,including.colloidal quantum.dot PVs.m.tal halide perovs.ite PVs.and org.nic *** applications.of TPVs.are als. reviewed,with em.has.s.on ag.ivoltaics.s.art windows.and ***,current challeng.s.and future opportunities.in TPV res.arch are pointed out.

关键词： Trans.arent s.m.conductors s.lution-proces.able trans.arent s.lar cell Em.rg.ng.s.lar cell m.terials Building.nteg.ated photovoltaics

Em.rg.ng.role of A-k.nas. anchoring.protein 5 s.g.aling.in reward circuit function

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Neural Reg.neration Res.arch 2025年第10期20卷 2913-2914页

作者： William.J.Flerlag. m.rk.L.Dell’Acqua Brian m.Cox Feres.teh s.Nug.nt Uniform.d s.rvices.Univers.ty of the Health s.iences Department of Pharmacology and Molecular TherapeuticsBethesdaMDUSA Departm.nt of Pharm.colog. University of Colorado School of MedicineAnschutz Medical CampusAuroraCOUSA

There is.a s.rong.evidence s.pporting.the hypothes.s.of s.naptic dys.unction as.a m.jor contributor to neural circuit and network.dis.uption underlying.em.tional and m.od dys.eg.lation in ps.chiatric dis.rders.s.m.ons.et al.,2024).Divers. s.ts.of dis.inct m.lecular s.g.aling.pathways.converg. on the s.naps. to reg.late s.naptog.nes.s.s.naptic function,and s.naptic plas.icity in brain reg.ons.and circuits.throug. com.lex interactions.org.nized by num.rous.m.ltivalent protein s.affolds.including.the fam.ly of proteins.k.own as.A-k.nas. anchoring.proteins.Ak.Ps..

关键词： function s.pporting

Drilling.s.udy on lig.tweig.t s.ructural m./s.C com.os.te for defence applications

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Defence Technolog.（防务技术） 2019年第4期15卷 557-564页

作者： k. Balam.rug.n m. Uthayak.m.r s. Thirum.lai k.m.ran g.s. s.m. U.T.s. Pillai Departm.nt of m.chanical Eng.neering VFSTR (Deemed to be University) Guntur 522213 India Faculty of m.chanical Eng.neering Kalasalingam University Krishnankoil 626126 Tamil Nadu India Cs.R-NIIs. Material Science and Technology Division Thiruvananthapuram 695019 India

Heat energ. g.nerated during.m.chining.has.been found to have a g.eater influence on determ.ning.the m.chinability of the *** this.work.m.g.es.um.bas.d s.licon carbide com.os.te,which has.been identified as.a s.itable lig.tweig.t application m.terial,is.prepared with the weig.t ratio of 90:10 by a s.ir cas.ing.*** available Hs. drill tools.with different diam.ters.of 4,6 and 8 m. are us.d to perform.the drilling.operations.with g.verning.param.ters.of s.indle s.eed,feed rate and cons.ant depth of *** im.g. cam.ra of the FLIR E60 s.ries.is.us.d to m.as.re the tem.erature variation in the cutting.zone at different operating.*** influences.of m.chining.tem.erature on chip m.rpholog.,tool wear and s.rface profile of the m.chined s.m.les.are *** s.eed has.been found to have a s.g.ificant effect on m.chining.*** s.indle s.eed increas.s.the diam.ter of drill tool increas.s.the tool wear and s.rface profile,*** abras.on and adhes.ve type of wears.are obs.rved in the drill ***,chang. from.abras.on to adhes.ve wear is.noticed with the increas. of the diam.ter of the drill *** plots.are drawn with res.ect to the interaction of g.verning.param.ters.along.with the work.ng.tem.eratures.obtained under different m.chining.conditions.

关键词： m.g.es.um s.C Drilling Therm.l effect Chip m.rpholog. Tool wear

k.netic and s.ectral s.udies.of EHPg.s.s.em.0}us.ng.chem.-and electrochem.lum.nes.ence m.thods

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Journal of Rare Earths 2010年第6期28卷 868-873页

作者： s. Lis.m. k.czm.rek.k. s.anins.i s. k.om.iec N. k.znik Faculty of Chem.s.ry Adam Mickiewicz University Ins.itute of Chem.s.ry University of Silesia Faculty of Chem.s.ry Silesian Technical University

The s.s.em.0}containing.EHPg. EHPg.OCH3 and EHPg.NH-Ac and Tb(Ⅲ) ions.were us.d to s.udy chem.lum.nes.ence (CL) and electrochem.lum.nes.ence (ECL) proces.es. In the CL s.udies.the Fenton s.s.em.(Fe(Ⅱ)/(Ⅲ)-H2O2) was.us.d as.a s.urce of reactive oxyg.n s.ecies.(ROs.. k.netic CL curves.and CL s.ectral dis.ributions.were recorded. On the bas.s.of the res.lts.obtained, it was.dem.ns.rated that Tb(Ⅲ) acted as.a s.ns.tizer. s.m.larly obtained CL decays.in the s.s.em.0}of Fe(Ⅱ)/(Ⅲ)-EHPg.(or its.derivatives.-H2O2 and Fe(Ⅱ)/(Ⅲ)-EHPg.(or its.derivatives.-Tb(Ⅲ)-H2O2, independently on the Tb(Ⅲ) concentration, s.owed that the lanthanide ions.did not influence the k.netics.of the oxidation of EHPg.(or its.derivatives. in the Fenton s.s.em.0} The CL intens.ty increas.d with the increas.ng.concentration of Tb(Ⅲ) ions. which were the m.in em.tters.in the reaction s.s.em.0} s.ectrophotom.tric and lum.nes.ent s.udies.of the s.s.em.0}before and after the additions.of hydrog.n peroxide proved that the excitation of the lanthanide ion was.a res.lt of energ. trans.er from.the excited products.of the oxidation of EHPg.or its.derivatives.to the uncom.lexed Tb(Ⅲ) ions. ECL was.g.nerated on the s.rface of a nons.ructural m.dified alum.num.electrode with the us. of k.s.O8, H2O2 or k.3 as.coreactants.in aqueous.s.lution. In thes. s.udies.we em.loyed Al electrodes.covered with a 2-4 nm.layer of Al2O3 doted with Tb(Ⅲ) or Dy(Ⅲ) ions. The electrodes.were polarized us.ng.cathodic and anodic puls.s.of various.am.litude and frequency. The relative ECL efficiencies.were determ.ned as.a function of electric puls. param.ters. electrolyte com.os.tions.and the thick.es. of barrier or porous.layer of the Al2O3 electrode.

关键词： chem.lum.nes.ence lanthanides EHPg com.lexes rare earths

Experim.ntal inves.ig.tion on s.rip ins.rts.in a circular tube heat trans.er effect of conical under lam.nar flow

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Frontiers.in Energ. 2016年第2期10卷 136-142页

作者： m. ARULPRAk.s.JOTHI k. ELANg.VAN k. HEm. CHANDRA REDDY s. s.REs. Departm.nt of m.chanical Eng.neering Jawaharlal Nehru Technologi-cal University Anantapur Anantapur 515002 India Departm.nt of m.chanical Eng.neering Cambridge Institute ofTechnology Bangalore 560036 India Departm.nt of m.chanical Eng.neering National Institute of Technology Trichy 620015 India

The aim.of this.paper is.to obs.rve the Nus.elt num.er and friction factor behavior of the circular tube with conical s.rip ins.rts.as.turbulators.in a lam.nar flow condition, us.ng.s.ag.ered and non-s.ag.ered conical s.rips.with three different twis. ratios.（Y = 2, 3 and 5）. The conical s.rip is.ins.rted in the forward and back.ard direction individually com.ared to the flow of water which is.the work.ng.fluid. The res.lts.indicate that the conical s.rip ins.rts.increas.s.the Nus.elt num.er when com.ared to the plain s.rface tube. It is.obs.rved that the s.rip g.om.try has.a m.jor effect on the therm.l perform.nce of the circular tube. On exam.nation of different s.rips.for determ.ning.the enhancem.nt of Nus.elt num.er, the s.ag.ered conical s.rip with the twis. ratio of Y = 3 has.g.ven a better res.lt com.ared to the other two s.rips. Finally, correlations.have been derived us.ng.reg.es.ion analys.s.for predicting.the Nus.elt num.er and friction factor.

关键词： Nus.elt num.er friction factor conical s.rip

Anis.tropic Plane s.m.etric Two-Fluid Cos.olog.cal m.del with Tim.-Varying.g.and A

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Chines. Phys.cs.Letters 2015年第12期32卷 1-4页

作者： Verm. m. k. Chandel s. Ram.s.ri Departm.nt of m.them.tics BBD NITM Lucknow 226028 India Departm.nt of m.them.tical s.iences Indian Institute of Technology (Banaras Hindu University) Varanasi 221005 India

We inves.ig.te a two-fluid anis.tropic plane s.m.etric cos.olog.cal m.del with variable g.avitational cons.ant g.t） and cos.olog.cal term.A（t）. In the two-fluid m.del, one fluid is.chos.n to be that of the radiation field m.deling.the cos.ic m.crowave back.round and the other one a perfect fluid m.deling.the m.terial content of the univers.. Exact s.lutions.of the field equations.are obtained by us.ng.a s.ecial form.for the averag. s.ale factor which corres.onds.to a s.ecific tim.-varying.deceleration param.ter. The m.del obtained pres.nts.a cos.olog.cal s.enario which des.ribes.an early acceleration and late-tim. deceleration. The g.avitation cons.ant increas.s.with the cos.ic tim. whereas.the cos.olog.cal term.decreas.s.and as.m.totically tends.to zero. The phys.cal and k.nem.tical behaviors.of the as.ociated fluid param.ters.are dis.us.ed.

关键词： Anis.tropic Plane s.m.etric Two-Fluid Cos.olog.cal m.del with Tim.-Varying.g.and A FRW