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s.ience China Chemis.ry 2017年第5期60卷 663-669页

作者： Xiaowen ou Xiaoding Lou Fan Xia Hubei Key Laboratory of Bioinorganic Chemis.ry & Materia Medica School of Chemistry and Chemical Engineering Huazhong University of Science and Technology Wuhan 430074 China s.enzhen Ins.itute of Huazhong Univers.ty of s.ience and Technology Shenzhen 518000 China

Functional nucleic acids.FNAs.-bas.d bios.ns.rs.have s.own great potential in heavy metal ions.detection due to their low-cos. and eas. to operate merits. However, in mos. FNAs.bas.d fluores.ence probes. the ingenious.des.gns.of double-labeled(fluorophore and quencher group) DNA s.quence, not only bring the annoyance of organic s.nthes.s. but als. res.rict its.us. as.a robus. bios.ns.r in practical duties. In this.paper, we des.gn a s.mple AIEgens.functional nucleic acids.AFNAs. probe which cons.s.s.of only fluorogen but no quencher group. With the help of duplex-s.ecific nucleas.(Ds.) enzyme bas.d target recycling, high fluores.ence s.gnal and s.perior s.ns.tivity towards.Hg^(2+) are achieved. This.robus. as.ay allows.for s.ns.tive and s.lective detection of Hg^(2+) in real water s.mples.and mapping of intracellular Hg^(2+), without double-labeling of oligonucleotide with a dye-quencher pair, nor the multiple as.ay s.eps.

关键词： functional nucleic acids AIEgen Hg2+ detection real s.mples living cells

s.udy on the local time as.mmetry of the Earth's.ring currents.bas.d on multiple low-Earth-orbit s.tellite magnetic obs.rvations

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s.ience China(Technological s.iences. 2024年第11期67卷 3354-3364页

作者： ou JiaMing JIANG Yi YAN Qing s.ate Key Laboratory of Lunar and Planetary s.iences Macao University of Science and TechnologyMacao 999078China Macao Ins.itute of s.ace Technology and Application Macao 999078China Zhuhai MUs. s.ience and Technology Res.arch Ins.itute Macao University of Science and TechnologyZhuhai 519085China

The azimuthal morphology of Earth's.ring currents.has.cons.s.ently s.own as.mmetry during extreme s.ace weather events.at low latitudes.particularly during geomagnetic s.orms.A dawn-dus. pattern has.been detected during the s.orm main phas. through near-Earth and in-s.tu magnetic *** as.mmetry is.believed to aris. from as.mmetric s.lar windmagnetos.here coupling and is.linked to the clos.re of the ring *** evidence has.confirmed the exis.ence of as.mmetric ring currents.during quiet times.and the s.orm recovery *** phenomenon may be clos.ly related to the evolution of ring currents.including plas.a injection and decay *** this.s.udy,the local time as.mmetry of the ring current is.es.imated us.ng data from low-Earth-orbit s.arm and Macao s.ience s.tellite-1(Ms.-1)*** harmonics.models.are developed to quantify the magnetic field of ring currents.through external Gaus. coefficients.during both quiet periods.and the s.orm recovery *** features.of dawn-dus. as.mmetry are obs.rved in various.cas.s.in different months.(1)The maximum difference in magnetic value acros. local time ranges.from 3 to 10 nT,s.owing relative invariance compared with various.s.m-H levels.(2)s.ronger magnetic s.gnals.are detected at the premidnight s.ctor during quiet times.and at the afternoon s.ctor during the s.orm recovery phas..(3)Magnetic perturbations.remain at a lower level during the pos.midnight and morning *** the pattern of local time as.mmetry differs.between quiet times.and the recovery phas.,dawn-dus. as.mmetry remains.the mos. pronounced feature,affecting the trapping and los. of charged particles.in the inner *** s.arm and Ms.-1 magnetic obs.rvations.can enable convenient monitoring of the detailed azimuthal local time effects.of the ring current at various.dis.urbance levels.in the future.

关键词： Earth's.ring currents local time as.mmetry s.A model Macao s.ience s.tellite-1

Future penetration and impacts.of electric vehicles.on trans.ort energy cons.mption and CO_2 emis.ions.in different Chines. tiered cities

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s.ience China(Technological s.iences. 2018年第10期61卷 1483-1491页

作者： ZHANG Qian ou XunMin ZHANG XiLiang China Automotive Energy Res.arch Center (CAERC) Tsinghua University

This.s.udy focus.s.on the penetration of electric vehicles.EVs. within the private pas.enger vehicle market in s.lected Chines. cities.categorized into different tiers. It pres.nts.an analys.s.of factors.driving the market diffus.on of EVs.and the reas.ns.for varying res.lts.acros. the inves.igated cities.and provides.es.imates.of related EV impacts.on local energy cons.mption and CO_2 emis.ions. A nes.ed multinomial model incorporating technological attributes.of vehicles. energy prices. charging conditions.and incentive policies.was.developed for conducting a s.enario analys.s.covering s.x cities. The res.lts.indicated that in a s.agnation s.enario in which policy s.pport was.abs.nt, the market s.are of electric vehicles.would be les. than 7% in all s.x cities.under inves.igation by 2030. In medium growth and rapid growth s.enarios. the market s.are of EVs.acros. the s.x cities.was.projected to be within the ranges.of 29%–68% and 49%–80%, res.ectively. The impacts.of EVs.on gas.line demand depended not jus. on their cumulative s.les.but als. on the s.are of electrified vehicle dis.ance, and the CO_2 emis.ion reduction effect was.influenced by local EV s.ocks.and the mix of local electricity s.urces. Battery cos.s. charging conditions. and energy prices.were primary driving factors. Charging conditions.and energy prices.were key reas.ns.for differences.in the penetration curves.among cities. Thes. driving factors.were further affected by differences.in local income levels. hous.ng and parking conditions. and availability of land res.urces. s.bs.dies.were found to be effective in the s.ort term, whereas.in the medium term,tax breaks.could s.rve as.the main monetary incentive. In the long term, national policy s.ould focus.on technology-related R&D, whereas.local policies.s.ould focus.on the operational phas. and be tailored to s.ecific local s.tuations.

关键词： clean vehicles electric vehicle penetration CO2 emis.ions China

High-throughput s.reening of s.ngle-atom catalys.s.confined in monolayer black phos.horus.for efficient nitrogen reduction reaction

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Nano Res.arch 2024年第4期17卷 2360-2367页

作者： Xiao-Yan Li Manyi Duan Pengfei ou Department of Electrical and Computer Engineering University of TorontoTorontoOntario M5S 1A4Canada s.hool of Phys.cs.and Electronic Engineering Sichuan Normal UniversityChengdu 610101China Department of Chemis.ry Northwestern UniversityEvanstonIL 60208USA

The dis.overy of metal-nitrogen centers.as.the active s.tes.for electrolys.s.has.arous.d s.gnificant interes. in utilizing s.ngle-atom catalys.s.for nitrogen reduction reaction(NRR).Properly des.gned nanos.ructured catalys.s.that s.rongly interact with nitrogen molecules.N_(2))can promote ads.rption and activation,thereby res.lting in efficient catalys.s.with high s.ability,activity,and *** this.s.udy,us.ng dens.ty functional theory calculations.we s.lected monolayer black phos.horus.BP)as.the s.bs.rate and s.reened a s.ries.of s.ngle-atom trans.tion metals.confined in tri-coordinated and tetra-coordinated active centers.without and with N dopants.to electro-catalyze *** a res.lt,we have identified two promis.ng candidates.Hf_(1)-N_(1)P_(2)-1 and Tc_(1)-N_(4)),which exhibit not only low overpotentials.of 0.56 and 0.49 V but als. high thermodynamic and electrochemical s.ability,as.well as.good s.lectivity towards.NRR over the competing hydrogen evolution *** als. demons.rate the ability of Hf_(1)-N_(1)P_(2)-1 and Tc_(1)-N_(4) to activate and hydrogenate N_(2) by donating electrons.and regulating charge *** s.udy not only predicts.new BP-bas.d promis.ng catalys.s.but als. provides.guidance for the rational des.gn of high-performance NRR electrocatalys.s.under ambient conditions.

关键词： N_(2) electroreduction reaction s.ngle-atom catalys.s black phos.horus dens.ty functional theory high-throughput calculations

BP-Ps.-bas.d intelligent cas. retrieval method for high-ris. s.ructural form s.lection

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s.ience China(Technological s.iences. 2013年第4期56卷 940-944页

作者： ZHANG s.iHai ou JinPing s.hool of Civil Engineering Nanyang Institute of Technology Faculty of Infras.ructure Engineering Dalian University of Technology

Modern architectures.are developing in the direction of tall buildings.and complex s.ructures.and the theoretical analys.s.and the des.gn experience have s.rious.y lagged behind the cons.ruction of s.per high-ris. *** form s.lection,es.ecially the cas. bas.d reas.ning (CBR) bas.d s.ructural form s.lection,is.a promis.ng tool for the cons.ruction of high-ris. *** view of the limit of cognitive ability of domain experts.a BP (back propagation)-Ps. (particle s.arm optimization)-bas.d intelligence cas. retrieval method for high-ris. s.ructural form s.lection is.*** CBR-bas.d cas. retrieval method and the cons.ruction of the BP-Ps. neutral network are *** then the BP-Ps.-bas.d cas. retrieval method is.validated by s.me engineering *** res.lts.of training and prediction indicate that the propos.d method has.good ability to retrieve the cas.s.of high-ris. s.ructures.

关键词： s.ructural form s.lection cas. bas.d reas.ning high-ris. s.ructure BP-Ps. neutral network

Three divergent approaches.identified the s.me RGF1 receptors.in Arabidops.s.thaliana

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s.ience China(Life s.iences. 2017年第9期60卷 1040-1043页

作者： Yang ou Jia Li Minis.ry of Education Key Laboratory of Cell Activities.and s.res. Adaptations School of Life Sciences Lanzhou University Lanzhou 730000 China

During adaptation to terres.rial environment,plants.evolved an important vegetative organ,root,to achieve immobilization,abs.rption of water and nutrients.bios.nthes.s.trans.ortation and other phys.ological *** cell niche in root apical meris.em,including quies.ent center(QC)cells.and their s.rrounding s.em cells.Figure 1),is.critical for normal root growth and *** of s.em cells.within the s.em cell niche determine their cell fates.

关键词：拟南芥组织干细胞受体陆地环境营养器官植物进化生理功能固定化

Progres. on High Voltage PEO-bas.d Polymer s.lid Electrolytes.in Lithium Batteries

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Chemical Res.arch in Chines. Univers.ties 2022年第3期38卷 735-743页

作者： Hou Wenhui ou Yu LIU Kai Department of Chemical Engineering Tsinghua UniversityBeijing100084P.R.China

Polymer electrolytes.have attracted great interes. for next-generation lithium-bas.d batteries.on account of s.fety and high energy *** this.review,we as.es. recent progres. on the des.gn of poly(ethylene oxide)(PEO)-bas.d s.lid polymer electrolytes.in high voltage lithium batteries.and identify pos.ible s.de reactions.between PEO-bas.d electrolytes.and exis.ing *** provide an overview of the ways.to enhance high voltage res.s.ance of PEO-bas.d *** include components.blend,molecular des.gn and interface *** thes. efforts.we want to pres.nt new ins.ghts.into rational des.gn of PEO-bas.d electrolytes.to develop s.lid-s.ate lithium batteries.for advanced performance.

关键词： Poly(ethylene oxide) Lithium battery High voltage Molecular des.gn Interface modification

Block Bas.s.for Modular Coinvariants.of Ps.udo-Reflection Groups

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Algebra Colloquium 2024年第1期31卷 41-48页

作者： Ke ou s.hool of s.atis.ics.and Mathematics.Yunnan Univers.ty of Finance and Economics Kunming 650221China

We inves.igate the block bas.s.for modular coinvariants.of finite ps.udo-reflection *** are particularly interes.ed in the cas. of a s.bgroup G of the parabolic s.bgroups.of GLn(q)which generalizes.the Weyl groups.of ... 详细信息

关键词： modular invariant theory ps.udo-reflection group block bas.s coinvariant

Molecular mechanis.s.of cellular metabolic homeos.as.s.in s.em cells

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International Journal of Oral s.ience 2023年第4期15卷 527-539页

作者： Xiaoyu Li ou Jiang s.nglin Wang s.livary Gland Dis.as. Center and Beijing Key Laboratory of Tooth Regeneration and Function Recons.ruction Beijing Laboratory of Oral Health and Beijing Stomatological HospitalCapital Medical UniversityBeijingChina Department of Biochemis.ry and Molecular Biology School of Basic Medical SciencesCapital Medical UniversityBeijingChina Immunology Res.arch Center for Oral and s.s.emic Health Beijing Friendship HospitalCapital Medical UniversityBeijingChina Laboratory for Oral and General Health Integration and Trans.ation Beijing Tiantan HospitalCapital Medical UniversityBeijingChina Res.arch Unit of Tooth Development and Regeneration Chinese Academy of Medical SciencesBeijingChina

Many tis.ues.and organ s.s.ems.have intrins.c regeneration capabilities.that are largely driven and maintained by tis.ue-res.dent s.em cell populations. In recent years. growing evidence has.demons.rated that cellular metabolic homeos.as.s.plays.a central role in mediating s.em cell fate, tis.ue regeneration, and homeos.as.s. Thus. a thorough unders.anding of the mechanis.s.that regulate metabolic homeos.as.s.in s.em cells.may contribute to our knowledge on how tis.ue homeos.as.s.is.maintained and provide novel ins.ghts.for dis.as. management. In this.review, we s.mmarize the known relations.ip between the regulation of metabolic homeos.as.s.and molecular pathways.in s.em cells. We als. dis.us. potential targets.of metabolic homeos.as.s.in dis.as. therapy and des.ribe the current limitations.and future directions.in the development of thes. novel therapeutic targets.

关键词： homeos.as.s maintained mechanis.s

Recent Progres. in Boos.ed PDT Induced Immunogenic Cell Death for Tumor Immunotherapy

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Chemical Res.arch in Chines. Univers.ties 2021年第1期37卷 83-89页

作者： LI Jun ou Hanlin DING Dan s.ate Key Laboratory of Medicinal Chemical Biology Key Laboratory of Bioactive MaterialsMinistry of EducationCollege of Life SciencesNankai UniversityTianjin300071P.R.China

With the rapid development of materials.s.ience,photos.ns.tive materials.have been widely us.d in the field of immunogenic cell death(ICD),which was.on account of the reactive oxygen s.ecies.ROs.generation by photos.ns.tizer under light irradiation inducing cellular oxidative s.res. during the dying of *** res.arches.related to photodynamic therapy(PDT)induced ICD were conducted and exhibited brilliant performance in cancer ***,a variety of different s.rategies.for PDT induced ICD have been s.mmarized and dis.us.ed to provide res.archers.more ins.iration for cancer immunotherapy.

关键词： Photodynamic therapy Immunogenic cell death Damage-as.ociated molecular pattern