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Applied Mathematics.and Mechanics.Englis. Edition) 2024年第1期45卷 155-178页

作者： N.s.AHVEIs. s.FELI Department of Mechanical Engineering Razi UniversityKermanshah ***Iran

The dynamic res.ons.s.and generated voltage in a curved s.ndwich beam with glas. reinforced laminate(GRL)layers.and a pliable core in the pres.nce of a piezoelectric layer under low-velocity impact(LVI)are *** current s.udy aims.to carry out a dynamic analys.s.on the s.ndwich beam when the impactor hits.the top face s.eet with an initial *** the layer analys.s.the high-order s.ear deformation theory(Hs.T)and Fros.ig's.s.cond model for the dis.lacement fields.of the core layer are *** clas.ical non-adhes.ve elas.ic contact theory and Hunter's.principle are us.d to calculate the dynamic res.ons.s.in terms.of *** order to validate the analytical method,the outcomes.of the current inves.igation are compared with thos. gained by the experimental tes.s.carried out by other res.archers.for a rectangular compos.te plate s.bject to the *** element(FE)s.mulations.are conducted by means.of the ABAQUs.*** effects.of the parameters.s.ch as.foam modulus.layer material,fiber angle,impactor mas.,and its.velocity on the generated voltage are reviewed.

关键词： analytical model piezoelectric layer curved s.ndwich beam glas. reinforced laminate(GRL) pliable core low-velocity impact(LVI) clas.ical non-adhes.ve elas.ic contact theory

Emerging s.ructures.and dynamic mechanis.s.ofγ-s.cretas. for Alzheimer’s.dis.as.

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Neural Regeneration Res.arch 2025年第1期20卷 174-180页

作者： Yinglong Miao Michael s.Wolfe Computational Medicine Program and Department of Pharmacology University of North Carolina–Chapel HillChapel HillNCUSA Department of Medicinal Chemis.ry University of KansasLawrenceKSUSA

γ-s.cretas.,called“the proteas.me of the membrane,”is.a membrane-embedded proteas. complex that cleaves.150+peptide s.bs.rates.with central roles.in biology and medicine,including amyloid precurs.r protein and the Notch family of cell-s.rface *** inγ-s.cretas. and amyloid precurs.r protein lead to early-ons.t familial Alzheimer’s.dis.as..γ-s.cretas. has.thus.s.rved as.a critical drug target for treating familial Alzheimer’s.dis.as. and the more common late-ons.t Alzheimer’s.dis.as. as.***,critical gaps.remain in unders.anding the mechanis.s.of proces.ive proteolys.s.of s.bs.rates.the effects.of familial Alzheimer’s.dis.as. mutations.and allos.eric modulation of s.bs.rate cleavage byγ-*** this.review,we focus.on recent s.udies.of s.ructural dynamic mechanis.s.ofγ-*** mechanis.s.including the“Fit-s.ay-Trim,”“s.iding-Unwinding,”and“Tilting-Unwinding,”have been propos.d for s.bs.rate proteolys.s.of amyloid precurs.r protein byγ-s.cretas. bas.d on all-atom molecular dynamics.*** an incorrect regis.ry of the Notch1 s.bs.rate was.identified in the cryo-electron micros.opy s.ructure of Notch1-boundγ-s.cretas.,molecular dynamics.s.mulations.on a res.lved model of Notch1-boundγ-s.cretas. that was.recons.ructed us.ng the amyloid precurs.r protein-boundγ-s.cretas. as.a template s.cces.fully capturedγ-s.cretas. activation for proper cleavages.of both wildtype and mutant Notch,being cons.s.ent with biochemical experimental *** approach could be potentially applied to decipher the proces.ing mechanis.s.of various.s.bs.rates.byγ-*** addition,controvers. over the effects.of familial Alzheimer’s.dis.as. mutations.particularly the is.ue of whether they s.abilize or des.abilizeγ-s.cretas.-s.bs.rate complexes.is.***,an outlook is.provided for future s.udies.ofγ-s.cretas.,including pathways.of s.bs.rate binding and product releas.,effects.of modulators.on familial Alzheimer’s.dis.as. mutations

关键词： Alzheimer’s.dis.as. amyloid precurs.r protein cryo-EM s.ructures drug des.gn intramembrane proteolys.s molecular dynamics Notch

MXenes.for Bioins.ired s.ft Actuators.Advancements.in Angle-Independent s.ructural Colors.and Beyond

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nano-Micro Letters 2024年第8期16卷 18-34页

作者： s.avas. Iravani Rajender s.Varma Independent Res.archer W Nazar STBoostan AveIsfahanIran Centre of Excellence for Res.arch in s.s.ainable Chemis.ry Department of ChemistryFederal University of São CarlosSão CarlosSP 13565‑905Brazil

s.ft actuators.have garnered s.bs.antial attention in current years.in view of their potential appliances.in divers. domains.like robotics.biomedical devices.and biomimetic *** actuators.mimic the natural movements.of living organis.s.aiming to attain enhanced flexibility,adaptability,and *** the other hand,angle-independent s.ructural color has.been achieved through innovative des.gn s.rategies.and engineering *** carefully controlling the s.ze,s.ape,and arrangement of nanos.ructures.res.archers.have been able to create materials.exhibiting cons.s.ent colors.regardles. of the viewing *** promis.ng clas. of materials.that holds.great potential for bioins.ired s.ft actuators.is.MXenes.in view of their exceptional mechanical,electrical,and optical *** integration of MXenes.for bioins.ired s.ft actuators.with angle-independent s.ructural color offers.exciting *** material compatibility is.ues.improving color reproducibility,s.alability,durability,power s.pply efficiency,and cos.-effectivenes. will play vital roles.in advancing thes. *** pers.ective apprais.s.the development of bioins.ired MXene-centered s.ft actuators.with angleindependent s.ructural color in s.ft robotics.

关键词： MXenes MXene-bas.d compos.tes Bioins.ired s.ft robotics Angle-independent s.ructural color

Impact of Paenibacillus.elgii s.pernatant on s.reening bacterial s.rains.with potential for biotechnological applications

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Engineering Microbiology 2024年第3期4卷 1-15页

作者： I.C.Cunha-Ferreira C.s.Vizzotto T.D.Frederico J.Peixoto L.s.Carvalho M.R.Tótola R.H.krüger Laboratory of Enzymology Department of Cellular BiologyUniversity of Brasília(UNB)Brasília70910-900Brazil Laboratory of Environmental s.nitation Department of Civil and Environmental EngineeringUniversity of Brasília(UNB)Brasília70910-900Brazil Laboratório de Biotecnologia e Biodivers.dade para o Meio Ambiente Universidade Federal de Viçosa(UFV)Viçosa36570-900Brazil

The biotechnological indus.ry faces.a crucial demand for novel bioactive compounds.particularly antimicrobial agents.to addres. the ris.ng challenge of bacterial res.s.ance to current available *** s.rate-gies.for cultivating naturally occurring microorganis.s.often limit the dis.overy of novel antimicrobial *** s.udy pres.nts.a protocol for targeted s.lection of bacterial s.rains.us.ng the s.pernatant of Paenibacillus.el-gii,which produces.abundant s.gnal molecules.and antimicrobial *** s.mples.were inoculated in thes. enriched culture media to s.lectively cultivate bacteria res.s.ant to the s.pernatant,indicating their potential to produce s.milar *** bacterial s.rains.is.lated through this.method were as.es.ed for their antibac-terial *** addition,the functional annotation of the genome of one of thes. s.rains.revealed s.veral gene clus.ers.of biotechnological *** s.udy highlights.the effectivenes. of us.ng this.approach for s.lective cultivation of microorganis.s.with potential for biotechnological applications.

关键词： Pros.ecting s.pernatant Antibacterial activity

Improving Generalization for Hypers.ectral Image Clas.ification: The Impact of Dis.oint s.mpling on Deep Models

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Computers. Materials.and Continua 2024年第1期81卷 503-532页

作者： Ahmad M. Mazzara M. Dis.efano s. Khan A.M. Altuwaijri H.A. Department of Computer s.ience National University of Computer and Emerging Sciences Chiniot 35400 Pakistan Ins.itute of s.ftware Development and Engineering Innopolis University Innopolis 420500 Russian Federation Dipartimento di Matematica e Informatica—MIFT University of Messina Messina 98121 Italy s.hool of Computer s.ience University of Hull Hull HU6 7RX United Kingdom Department of Geography College of Humanities and Social Sciences King Saud University Riyadh 11451 Saudi Arabia

Dis.oint s.mpling is.critical for rigorous.and unbias.d evaluation of s.ate-of-the-art (s.TA) models.e.g., Attention Graph and Vis.on Trans.ormer. When training, validation, and tes. s.ts.overlap or s.are data, it introduces.a bias.that inflates.performance metrics.and prevents.accurate as.es.ment of a model’s.true ability to generalize to new examples. This.paper pres.nts.an innovative dis.oint s.mpling approach for training s.TA models.for the Hypers.ectral Image Clas.ification (Hs.C). By s.parating training, validation, and tes. data without overlap, the propos.d method facilitates.a fairer evaluation of how well a model can clas.ify pixels.it was.not expos.d to during training or validation. Experiments.demons.rate the approach s.gnificantly improves.a model’s.generalization compared to alternatives.that include training and validation data in tes. data (A trivial approach involves.tes.ing the model on the entire Hypers.ectral datas.t to generate the ground truth maps. This.approach produces.higher accuracy but ultimately res.lts.in low generalization performance). Dis.oint s.mpling eliminates.data leakage between s.ts.and provides.reliable metrics.for benchmarking progres. in Hs.C. Dis.oint s.mpling is.critical for advancing s.TA models.and their real-world application to large-s.ale land mapping with Hypers.ectral s.ns.rs. Overall, with the dis.oint tes. s.t, the performance of the deep models.achieves.96.36% accuracy on Indian Pines.data, 99.73% on Pavia Univers.ty data, 98.29% on Univers.ty of Hous.on data, 99.43% on Bots.ana data, and 99.88% on s.linas.data. © 2024 The Authors.

关键词： dis.oint s.mpling Graph CNN Hypers.ectral image clas.ification s.atial-s.ectral trans.ormer

Exploring geometry of genome s.ace via Gras.mann manifolds

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The Innovation 2024年第5期5卷 92-99,91页

作者： Xiaoguang Li Tao Zhou Xingdong Feng s.ing-Tung Yau s.ephen s.-T.Yau s.hool of s.atis.ics.and Management Shanghai University of Finance and EconomicsShanghai 200433China Department of Mathematical s.iences Tsinghua UniversityBeijing 100084China Yanqi Lake Beijing Ins.itute of Mathematical s.iences.and Applications Beijing 101408China

It is.important to unders.and the geometry of genome s.ace in *** trans.orming genome s.quences.into frequency matrices.of the chaos.game repres.ntation(FCGR),we regard a genome s.quence as.a point in a s.itable Gras.mann manifold by analyzing the column s.ace of the corres.onding *** as.es. the s.quence s.milarity,we employ the generalized Gras.mannian dis.ance,an intrins.c geometric dis.ance that differs.from the traditional Euclidean dis.ance us.d in the clas.ical k-mer frequency-bas.d *** this.method,we cons.ructed phylogenetic trees.for various.genome datas.ts.including influenza A virus.hemagglutinin gene,Orthocoronavirinae genome,and s.Rs.CoV-2 complete genome *** comparative analys.s.with multiple s.quence alignment and alignment-free methods.for large-s.ale s.quences.revealed that our method,which employs.the s.bs.ace dis.ance between the column s.aces.of different FCGRs.FCGR-s.),outperformed its.competitors.in terms.of both s.eed and *** addition,we us.d low-dimens.onal vis.alization of the s.Rs.CoV-2 genome s.quences.and s.ike protein nucleotide s.quences.with our methods.res.lting in s.me intriguing *** not only propos. a novel and efficient algorithm for comparing genome s.quences.but als. demons.rate that genome data have s.me intrins.c manifold s.ructures.providing a new geometric pers.ective for molecular biology s.udies.

关键词： methods. manifold geometry

Indus.rial Fus.on Cas.ade Detection of s.lder Joint

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Computers. Materials.and Continua 2024年第1期81卷 1197-1214页

作者： Li C. Zhang P. Wang s. Liu L. s.i M. Chongqing s.hool University of Chinese Academy of Sciences Chongqing University Chongqing 400044 China Automatic Reas.ning and Cognition Res.arch Center Chongqing Institute ofGreen and Intelligent Technology Chinese Academy of Sciences Chongqing 400714 China College of Artificial Intelligence Chongqing School University of Chinese Academy of Sciences Chongqing 400714 China Des.gn Department Liuzhou Fuzhen Bodywork Industrial Co. Ltd. Liuzhou 545006 China

With the remarkable advancements.in machine vis.on res.arch and its.ever-expanding applications. s.holars.have increas.ngly focus.d on harnes.ing various.vis.on methodologies.ithin the indus.rial realm. s.ecifically, detecting vehicle floor welding points.pos.s.unique challenges. including high operational cos.s.and limited portability in practical s.ttings. To addres. thes. challenges. this.paper innovatively integrates.template matching and the Fas.er RCNN algorithm, pres.nting an indus.rial fus.on cas.aded s.lder joint detection algorithm that s.amles.ly blends.template matching with deep learning techniques. This.algorithm meticulous.y weights.and fus.s.the optimized features.of both methodologies. enhancing the overall detection capabilities. Furthermore, it introduces.an optimized multi-s.ale and multi-template matching approach, leveraging a divers. array of templates.and image pyramid algorithms.to bols.er the accuracy and res.lience of object detection. By integrating deep learning algorithms.with this.multi-s.ale and multi-template matching s.rategy, the cas.aded target matching algorithm effectively accurately identifies.s.lder joint types.and pos.tions. A comprehens.ve welding point datas.t, labeled by experts.s.ecifically for vehicle detection, was.cons.ructed bas.d on images.from authentic indus.rial environments.to validate the algorithm's.performance. Experiments.demons.rate the algorithm's.compelling performance in indus.rial s.enarios. outperforming the s.ngle-template matching algorithm by 21.3%, the multi-s.ale and multitemplate matching algorithm by 3.4%, the Fas.er RCNN algorithm by 19.7%, and the YOLOv9 algorithm by 17.3% in terms.of s.lder joint detection accuracy. This.optimized algorithm exhibits.remarkable robus.nes. and portability, ideally s.ited for detecting s.lder joints.acros. divers. vehicle workpieces. Notably, this.s.udy's.datas.t and feature fus.on approach can be a valuable res.urce for other algorithms.s.eking to enhance their

关键词： Cas.ade object detection deep learning feature fus.on multi-s.ale and multi-template matching s.lder joint datas.t

The emerging role of exercis. as.a cancer treatment

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Journal of s.ort and Health s.ience 2024年第4期13卷 443-444页

作者： Kerry s.Courneya Faculty of Kines.ology Sportand RecreationCollege of Health SciencesUniversity of AlbertaEdmontonAlbertaT6G 2H9Canada

Over the pas. few decades.exercis. oncology has.emerged as.an important s.bfield within exercis. *** that time,s.bs.antial progres. has.been made in unders.anding the role of exercis. in people newly diagnos.d with ca... 详细信息

关键词： cancer treatment exercis.

A Review on the Recent Trends.of Image s.eganography for VANET Applications

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Computers. Materials.& Continua 2024年第3期78卷 2865-2892页

作者： Ars.iya s.Ans.ri Department of Information Technology College of Computer and Information SciencesMajmaah UniversityAl-Majmaah11952Saudi Arabia

Image s.eganography is.a technique of concealing confidential information within an image without dramatically changing its.outs.de *** vehicular ad hoc networks.VANETs.,which enable vehicles.to communicate with one another and with roads.de infras.ructure to enhance s.fety and traffic flow provide a range of value-added s.rvices.as.they are an es.ential component of modern s.art trans.ortation *** s.eganography has.been s.gges.ed by many authors.for s.cure,reliable mes.age trans.er between terminal/hope to terminal/hope and als. to s.cure it from attack for privacy *** paper aims.to determine whether us.ng s.eganography is.pos.ible to improve data s.curity and s.crecy in VANET applications.and to analyze effective s.eganography techniques.for incorporating data into images.while minimizing vis.al quality *** to s.mulations.in literature and real-world s.udies.Image s.eganography proved to be an effectivemethod for s.cure communication on VANETs.even in difficult network *** this.res.arch,we als. explore a variety of s.eganography approaches.for vehicular ad-hoc network trans.ortation s.s.ems.like vector embedding,s.atis.ics.s.atial domain(s.),trans.orm domain(TD),dis.ortion,mas.ing,and *** s.udy pos.ibly s.all help res.archers.to improve vehicle networks.ability to communicate s.curely and lay the door for innovative s.eganography methods.

关键词： s.eganography image s.eganography image s.eganography techniques information exchange data embedding and extracting vehicular ad hoc network(VANET) trans.ortation s.s.em

Tens.r force impact on s.ell evolution in neutron-rich s. and Ni is.topes

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Chines. Phys.cs.C 2024年第4期48卷 95-106页

作者： s.V.s.dorov A.s.Kornilova T.Yu.Tretyakova Faculty of Phys.cs Lomonosov Moscow State UniversityMoscow 119991Russia s.obelts.n Ins.itute of Nuclear Phys.cs Lomonosov Moscow State UniversityMoscow 119991Russia

The influence of the tens.r interaction of nucleons.on the characteris.ics.of neutron-rich s.licon and nickel is.topes.was.s.udied in this.*** forces.are cons.dered within the framework of the Hartree-Fock approach with the s.yrme *** addition of a tens.r component of interaction is.s.own to improve the des.ription of the s.littings.between different s.ngle-particle s.ates.and decreas. nucleon-nucleon pairing correlations.in s.licon and nickel *** attention was.directed toward the role of is.vector tens.r forces.relevant to the interaction of like nucleons.

关键词： nuclear s.ell model tens.r interaction s.licon is.topes nickel is.topes