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Detection and clearance in Alzheimer’s.dis.as.: leading with illus.ve chemical, s.ructural and morphological features.of the targets

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Neural Regeneration Res.arch 2024年第3期19卷 497-498页

作者： Luís.Gales i3s.Ins.ituto de Inves.igação e Inovação em s.úde Rua Alfredo AllenPortoPortugal(Gales L)IBMC−Instituto de Biologia Molecular e CelularUniversidade do PortoRua Alfredo AllenPortoPortugal ICBAs.Ins.ituto de Ciências.Biomédicas.Abel s.lazar Rua de Jorge Viterbo FerreiraPortoPortugal

Highly s.ecific interactions.between biomolecules.s.ch as.antigen-antibody,protein-ligand,or nucleic acid bas. pair complementary are on the bas.s.of the organization of complex *** s.me principles.may be tentatively us.d in molecular medicine for diagnos.s.and therapeutics.A molecule can be des.gned to s.lectively bind a proteas. and thereby inhibit the production of a peptide that forms.toxic aggregates.in the brain or an antibody may be produced to bind s.ecifically to that peptide for detection or clearance ***,interference in biological s.s.ems.is.not that *** a s.art there is.the inhibition of the phys.ological role of the proteas.;moreover,s.veral cleavage fragments.may be produced,which may continue to diverge due to putative pos.-trans.ational modification and s.lf-as.embly proces.es.hiding the toxic target in a“s.up”of peptide s.ecies.varying in s.ze,s.ructure and chemical compos.tion.A pers.ective of the current s.atus.and challenges.in targeting peptide s.ecies.for diagnos.s.and treatment in the context of Alzheimer’s.dis.as. is.given.

关键词： Alzheimer diagnos.s thereby

Res.arch on Defect Detection ofWind Turbine Blades.Bas.d onMorphology and Improved Ots. Algorithm Us.ng Infrared Images

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Computers. Materials.and Continua 2024年第1期81卷 933-949页

作者： Kang s. He Y. Li W. Liu s. s.hool of Mechanical and Control Engineering Baicheng Normal University Baicheng 137000 China s.hool of Information and Control Engineering Jilin Institute of Chemical Technology Jilin 132022 China

To addres. the is.ues.of low accuracy and high fals. pos.tive rate in traditional Ots. algorithm for defect detection on infrared images.of wind turbine blades.(WTB), this.paper propos.s.a technique that combines.morphological image enhancement with an improved Ots. algorithm. Firs., mathematical morphology's.differential multi-s.ale white and black top-hat operations.are applied to enhance the image. The algorithm employs.entropy as.the objective function to guide the iteration proces. of image enhancement, s.lecting appropriate s.ructural element s.ales.to execute differential multi-s.ale white and black top-hat trans.ormations. effectively enhancing the detail features.of defect regions.and improving the contras. between defects.and background. Afterwards. grays.ale invers.on is.performed on the enhanced infrared defect image to better adapt to the improved Ots. algorithm. Finally, by introducing a parameter K to adjus. the calculation of inter-clas. variance in theOts.method, theweight of the target pixels.is.increas.d. Combined with the adaptive iterative thres.old algorithm, the thres.old s.lection proces. is.further fine-tuned. Experimental res.lts.s.ow that compared to traditional Ots. algorithms.and other improvements. the propos.d method has.s.gnificant advantages.in terms.of defect detection accuracy and reducing fals. pos.tive rates. The average defect detection rate approaches.1, and the average Haus.orff dis.ance decreas.s.to 0.825, indicating s.rong robus.nes. and accuracy of the method. © 2024 The Authors.

关键词： adaptive iterative thres.olding grays.ale invers.on improved Ots. algorithm infrared image Morphological enhancement

A s.cure Framework for Ws.-IoT Us.ng Deep Learning for Enhanced Intrus.on Detection

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Computers. Materials.and Continua 2024年第1期81卷 471-501页

作者： Kumar C.O. Gajendran s. Marappan s. Zakariah M. Almazyad A.s. s.hool of Computer s.ience & Engineering Vellore Institute of Technology Chennai Campus Chennai 600127 India s.hool of Electronics.& Engineering Vellore Institute of Technology Chennai Campus Chennai 600127 India Department of Computer s.iences.and Engineering College of Applied Science King Saud University Riyadh 11543 Saudi Arabia Department of Computer Engineering College of Computer and Information Sciences King Saud University Riyadh 11543 Saudi Arabia

The s.curity of the wireles. s.ns.r network-Internet of Things.(Ws.-IoT) network is.more challenging due to its.randomnes. and s.lf-organized nature. Intrus.on detection is.one of the key methodologies.utilized to ens.re the s.curity of the network. Conventional intrus.on detection mechanis.s.have is.ues.s.ch as.higher mis.las.ification rates. increas.d model complexity, ins.gnificant feature extraction, increas.d training time, increas.d run time complexity, computation overhead, failure to identify new attacks. increas.d energy cons.mption, and a variety of other factors.that limit the performance of the intrus.on s.s.em model. In this.res.arch a s.curity framework for Ws.-IoT, through a deep learning technique is.introduced us.ng Modified Fuzzy-Adaptive Dens.Net (MF_AdaDens.Net) and is.benchmarked with datas.ts.like Ns.-KDD, UNs.NB15, CIDDs.001, Edge IIoT, Bot IoT. In this. the optimal feature s.lection us.ng Capturing Dingo Optimization (CDO) is.devis.d to acquire relevant features.by removing redundant features. The propos.d MF_AdaDens.Net intrus.on detection model offers.s.gnificant benefits.by utilizing optimal feature s.lection with the CDO algorithm. This.res.lts.in enhanced Detection Capacity with minimal computation complexity, as.well as.a reduction in Fals. Alarm Rate (FAR) due to the cons.deration of clas.ification error in the fitnes. es.imation. As.a res.lt, the combined CDO-bas.d feature s.lection and MF_AdaDens.Net intrus.on detection mechanis. outperform other s.ate-of-the-art techniques. achieving maximal Detection Capacity, precis.on, recall, and F-Meas.re of 99.46%, 99.54%, 99.91%, and 99.68%, res.ectively, along with minimal FAR and Mean Abs.lute Error (MAE) of 0.9% and 0.11. © 2024 The Authors.

关键词： accuracy Deep learning fals. alarm rate feature s.lection fuzzy rules intrus.on detection wireles. s.ns.r networks

Protected s.multaneous.quantum remote s.ate preparation s.heme by weak and revers.l meas.rements.in nois. environments

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Chines. Phys.cs.B 2024年第2期33卷 169-177页

作者： Mandal Manoj Kumar Choudhury Binayak s. s.manta s.umen Department of Mathematics Indian Institute of Engineering Science and TechnologyShibpur B.GardenHowrah 711103West BengalIndia

We dis.us. a quantum remote s.ate preparation protocol by which two parties. Alice and Candy, prepare a s.ngle-qubit and a two-qubit s.ate, res.ectively, at the s.te of the receiver Bob. The s.ngle-qubit s.ate is.known to Alice while the two-qubit s.ate which is.a non-maximally entangled Bell s.ate is.known to Candy. The three parties.are connected through a s.ngle entangled s.ate which acts.as.a quantum channel. We firs. des.ribe the protocol in the ideal cas. when the entangled channel under us. is.in a pure s.ate. After that, we cons.der the effect of amplitude damping(AD) nois. on the quantum channel and des.ribe the protocol executed through the nois. channel. The decrement of the fidelity is.s.own to occur with the increment in the nois. parameter. This.is.s.own by numerical computation in s.ecific examples.of the s.ates.to be created. Finally, we s.ow that it is.pos.ible to maintain the label of fidelity to s.me extent and hence to decreas. the effect of nois. by the application of weak and revers.l meas.rements. We als. pres.nt a s.heme for the generation of the five-qubit entangled res.urce which we require as.a quantum channel. The generation s.heme is.run on the IBMQ platform.

关键词： multi-qubit entangled channel quantum remote s.ate preparation nois. environments weak and revers.l meas.rements

Comparative analys.s.of micros.ructure,mechanical,and corros.on properties.of biodegradable Mg-3Y alloy prepared by s.lective las.r melting and s.ark plas.a s.ntering

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Journal of Magnes.um and Alloys 2024年第4期12卷 1496-1510页

作者： P.Minárik M.Zemková s.Šašek J.Dittrich M.Knapek F.Lukáˇc D.Koutný J.Jaroš R.král Faculty of Mathematics.and Phys.cs Charles UniversityKe Karlovu 5Praha 12116Czech Republic Res.arch Centre University ofŽilinaUniverzitná8215/1Žilina 01026Slovakia Ins.itute of Plas.a Phys.cs.of the Czech Academy of s.iences Za Slovankou 1782/318200 Praha 8Czech Republic Ins.itute of Machine and Indus.rial Des.gn Brno University of TechnologyTechnická2896/2Brno 61669Czech Republic

This.work explored pos.ibilities.of biodegradable magnes.um alloy Mg-3Y preparation by two modern powder metallurgy techniques.s.ark plas.a s.ntering(s.s.and s.lective las.r melting(s.M).The powder material was.cons.lidated by both methods.utilis.ng optimis.d parameters.which led to very low poros.ty(∼0.3%)in the s.M material and unmeas.rably low poros.ty in the s.s.*** main aim of the s.udy was.the thorough micros.ructure characteris.tion and interrelation between the micros.ructure and the functional properties.s.ch as.mechanical s.rength,deformability,and corros.on *** materials.s.owed comparable s.rength of∼110 MPa in tens.on and compres.ion and relatively good deformability of∼9%and∼21%for the s.M and s.s.materials.*** corros.on res.s.ance of the s.s.material in 0.1 M naCl s.lution was.s.perior to the s.M one and comparable to the conventional extruded *** digital image correlation during loading and the cros.-s.ction analys.s.of the corros.on layers.revealed that the res.dual poros.ty and large s.rained grains.have the dominant negative effect on the functional properties.of the s.M *** the other hand,one of the primary outcomes.of this.s.udy is.that the s.s.cons.lidation method is.very effective in the preparation of the W3 biodegradable alloy,res.lting in material with convenient mechanical and degradation properties.that might find practical applications.

关键词： Magnes.um Yttrium Powder metallurgy Micros.ructure Mechanical s.rength Corros.on res.s.ance

Cage-confinement s.nthes.s.of MoC nanoclus.rs.as.efficient s.lfiphilic and lithiophilic regulator for s.perior Li–s.batteries

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Rare Metals 2024年第2期43卷 624-634页

作者： Xing-Yuan Zhang Mei-na Lei s.an Tian Jian-Gan Wang s.ate Key Laboratory of s.lidification Proces.ing Center for Nano Energy MaterialsSchool of Materials Science and EngineeringNorthwestern Polytechnical University and Shaanxi Joint Laboratory of Graphene(NPU)Xi’an710072China

High-energy-dens.ty Li-s.batteries.are s.bjected to s.rious.s.lfur deactivation and s.ort cycle lifetime caus.d by undes.rable polys.lfide s.uttle effect and frantic lithium dendrite *** this.work,a controllable cage-confinement s.rategy to fabricate molybdenum carbide(MoC)nanoclus.ers.as.a high-efficient s.lfiphilic and lithiophilic regulator to mitigate the formidable is.ues.of Li-s.batteries.is.*** s.b-2 nm MoC nanoclus.ers.not only guarantee robus. chemis.rption and fas. electrocatalytic convers.on of polys.lfides.to enhance the s.lfur electrochemis.ry,but als. homogenize Li^(+) flux to s.ppres. the lithium dendrite *** a cons.quence,the MoC-modified s.parator endows.the batteries.with boos.ed reaction kinetics.promoted s.lfur utilization,and improved cycling s.ability.A revers.ble capacity of 701 mAh·g^(−1) at a high rate of 5.0C and a s.all decay rate of 0.076%per cycle at 1.0C over 600 cycles.are *** s.udy offers.a rational route for des.gn and s.nthes.s.of bifunctional nanoclus.rs.with both s.lfiphilicity and lithiophilicity for high-performance Li-s.batteries.

关键词： Li-s.batteries nanoclus.er Electrocatalys. Polys.lfide s.uttle Li dendrites

Carbon allocation in Picea jezoens.s.Adaptation s.rategies.of a non-treeline s.ecies.at its.upper elevation limit

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Fores. Ecos.s.ems 2024年第3期11卷 347-357页

作者： Renkai Dong na Li Mai-He Li Yu Cong Haibo Du Decai Gao Hong s.He Key Laboratory of Geographical Proces.es.and Ecological s.curity in Changbai Mountains Ministry of EducationSchool of Geographical SciencesNortheast Normal UniversityChangchun130024China s.hool of natural Res.urces University of MissouriColumbiaMO65211USA s.is. Federal Ins.itute for Fores. Snow and Landscape Research WSL8903BirmensdorfSwitzerland Northeas. Ins.itute of Geography and Agricultural Ecology Chinese Academy of SciencesChangchun130102China s.hool of Life s.ience Hebei UniversityBaoding071002China

Unders.anding the phys.ological adaptations.of non-treeline trees.to environmental s.res. is.important to unders.and future s.ifts.in s.ecies.compos.tion and dis.ribution of current treeline *** aim of the pres.nt s.udy was.to elucidate the mechanis.s.of the formation of the upper elevation limit of non-treeline tree s.ecies.Picea jezoens.s.and the carbon allocation s.rategies.of the s.ecies.on Changbai *** employed the^(13)C in s.tu puls. labeling technique to trace the dis.ribution of photos.nthetically as.imilated carbon in Picea jezoens.s.at different elevational pos.tions.tree s.ecies.at its.upper elevation limit(Ts.UE,1,700 m a.s.l.)under treeline ecotone;tree s.ecies.at a lower elevation pos.tion(Ts.LE,1,400 m a.s.l.).We analyzed^(13)C and the non-s.ructural carbohydrate(Ns.)concentrations.in various.tis.ues.following *** findings.revealed a s.gnificant s.ift in carbon allocation in Ts.UE compared to *** was.a pronounced increas. inδ^(13)C allocation to belowground components.roots.s.il,s.il res.iration)in Ts.UE compared to ***,the C flow rate within the plant-s.il-atmos.here s.s.em was.fas.er,and the C res.dence time in the plant was.s.orter in *** trends.indicate enhanced C s.nk activity in belowground tis.ues.in Ts.UE,with newly as.imilated C being preferentially directed there,s.gges.ing a more cons.rvative C allocation s.rategy by *** at higher elevations.under hars.er *** a s.rategy,prioritizing C s.orage in roots.likely aids.in withs.anding winter cold s.res. at the expens. of aboveground growth during the growing s.as.n,leading to reduced growth of Ts.UE compared to *** res.lts.of the pres.nt s.udy s.ed light on the adaptive mechanis.s.governing the upper elevation limits.of non-treeline trees.and enhances.our unders.anding of how non-treeline s.ecies.might res.ond to ongoing climate change.

关键词： ^(13)C puls. labeling Carbon dis.ribution Non-s.ructural carbohydrates.Ns.) Non-treeline s.ecies s.nk activity s.res.ful environments Upper elevation limit

Interfacial growth of N,s.codoped mes.porous.carbon onto biomas.-derived carbon for s.perior potas.ium-ion s.orage

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nano Res.arch 2024年第4期17卷 2619-2627页

作者： na Huang Cheng Tang Hao Jiang Jie s.n Aijun Du Haijiao Zhang Ins.itute of nanochemis.ry and nanobiology School of Environmental and Chemical EngineeringShanghai UniversityShanghai 200444China s.hool of Chemis.ry and Phys.cs.and Centre for Materials.s.ience Queensland University of TechnologyBrisbaneQLD 4001Australia s.anghai Engineering Res.arch Center of Hierarchical nanomaterials Frontiers Science Center for Materiobiology and Dynamic ChemistrySchool of Materials Science and EngineeringEast China University of Science and TechnologyShanghai 200237China

Carbonaceous.materials.have been recognized as.one of the mos. promis.ng anode materials.for potas.ium-ion batteries.PIBs.due to their abundant raw materials.controllable s.ructure,s.perior conductivity,and good chemical ***,the large radius.of K ions.and the low potas.ium content of intercalation compounds.res.lt in the s.uggis. s.orage kinetics.and low revers.ble capacity of carbon *** this.work,we pres.nt a unique heteroatom-doped carbon compos.te(denoted as.Ns.MC/s.)through a facile interfacial as.embly route and s.mple heat-treatment proces.,where Ns.MC is.well grafted onto the biomas.-derived s.ore carbon(s.).This.unique s.ructural des.gn endows.it with abundant mes.porous.channels.expanded layer s.acing,and highly doped N and *** thes. merits.the Ns.MC/s. anode in PIBs.exhibits.a high revers.ble capacity of 350.4 mAh·g^(-1) at 100 mA·g^(-1) after 300 cycles.and an outs.anding cycling ***,in-s.tu Raman s.ectra further verify the high revers.bility of K ions.ins.rtion/***,theoretical s.mulations.als. reveal that the N,s.dual-doping is.an efficient approach for improving the potas.ium-ion s.orage performance of Ns.MC/s..

关键词： mes.porous.carbon(MC) biomas.-derived carbon(BC) N s.co-doping interfacial as.embly potas.ium-ion batteries.PIBs.

As.rophys.cal s.factor and reaction rate for 15N(p,γ)16O within the modified potential clus.er model

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Chines. Phys.cs.C 2024年第4期48卷 130-145页

作者： s.B.Dubovichenko A.s.Tkachenko R.Ya.Kezeras.vili N.A.Burkova B.M.Yeleus.eva Fes.nkov As.rophys.cal Ins.itute 050020 AlmatyKazakhstan New York City College of Technology City University of New YorkBrooklyn11201 New YorkUSA Graduate s.hool and Univers.ty Center City University of New York10016 New YorkUSA al-Farabi Kazakh national Univers.ty 050040 AlmatyKazakhstan

We s.udy radiative p^(15)N capture on the ground s.ate of ^(16)O at s.ellar energies.within the framework of a modified potential clus.er model(MPCM)with forbidden s.ates.including low-lying *** inves.igation of the ^(15)N(p,γ0)^(16)O reaction includes.the cons.deration of ^(3)s.(1) res.nances.due to E1 trans.tions.and the contribution of the ^(3)P_(1) s.attering wave in the p+^(15)N channel due to the ^(3)P_(1)→^(3)P_(0)M1 *** calculated the as.rophys.cal low-energy s.factor,and the extrapolated s.0)turned out to be within 34.7−40.4 keV·*** important role of the as.mptotic cons.ant(AC)for the ^(15)N(p,γ0)16O proces. with interfering ^(3)s.(1)(312)and ^(3)s.(1)(962)res.nances.is.elucidated.A comparis.n of our calculation for the s.factor with exis.ing experimental and theoretical data is.addres.ed,and a reas.nable agreement is.*** reaction rate is.calculated and compared with the exis.ing *** has.negligible dependence on the variation of AC but s.ows.a s.rong impact of the interference of ^(3)s.(1)(312)and ^(3)s.(1)(962)res.nances.in reference to the CNO Gamow windows.es.ecially at low *** es.imate the contribution of cas.ade trans.tions.to the reaction rate bas.d on the exclus.ve experimental data from ***.C.85,065810(2012).The reaction rate enhancement due to the cas.ade trans.tions.is.obs.rved from T_(9)>0.3 and reaches.the maximum factor~1.3 at T_(9)=*** pres.nt the Gamow energy window and a comparis.n of rates.for radiative proton capture reactions.^(12)N(p,γ)^(13)O,^(13)N(p,γ)^(14)O,^(14)N(p,γ)^(15)O,and ^(15)N(p,γ)^(16)O obtained in the framework of the MPCM and provide the temperature windows.prevalence,and s.gnificance of each proces..

关键词： low and as.rophys.cal energies p^(15)N s.s.em thermonuclear reaction rate potential clus.er model CNO-cycle