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Cellular & Molecular Immunology 2020年第7期17卷 680-681页

作者： Dusanka s.skundric Harley Y.Tse paul C.Montgomery Department of Biochemistry Microbiology and ImmunologyWayne State UniversitySchool of MedicineDetroitMIUSA

The article by Kulkarni et *** a description of some genetic and epigenetic interactions that determine the functional phenotypes of the chemokine receptor CCR5,which is critical to human immunodeficiency virus type 1(HIV-1)infection.1 significant advances in the genetic regulation of human diseases have been made through the use of genome-wide association studies(GWAss)over the past several *** daunting task of elucidating the cellular pathways that are critical to human disease regulation remains for many disease-associated coding genetic variants.

关键词： CCR5 epigenetic al.

Exploiting Deterministic TPG for Path Delay Testing

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Journal of Computer science & Technology 2000年第5期15卷 472-479页

作者：李晓维 paulY.s.Cheung DepartmentofComputerscience PekingUniversityBeijing100871P.R.China DepartmentofElectricalandElectronicEngineering TheUniversityofHongKongPokfulamRoadHongKongP.R.China

Detection of path delay faults requires two-pattern tests. BIsT technique provides a low-cost test solution. This paper proposes an approach to designing a cost-effective deterministic test pattern generator (TPG) for path delay testing. Given a set of pre-generated test-pairs with pre-determined fault coverage, a deterministic TPG is synthesized to apply the given test-pair set in a limited test time. To achieve this objective, configurable linear feedback shift register (LFsR) structures are used. Techniques are developed to synthesize such a TPG, which is used to generate an unordered deterministic test-pair set. The resulting TPG is very efficient in terms of hardware size and speed performance. simulation of academic benchmark circuits has given good results when compared to alternative solutions.

关键词： built-in self-test (BIsT) path delay testing deterministic TPG configurable LFsR

Phytochemical constituents and antibacterial efficacy of the flowers of Peltophomm pterocarpum(DC.) Baker ex Heyne

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Asian Pacific Journal of Tropical Medicine 2011年第9期4卷 735-738页

作者： sukumaran s Kiruba s Mahesh M Nisha sR Miller paul Z Ben CP Jeeva s Centre for Biodiversity and Biotechnology Department of BotanyN.M.Christian College.Marthandam.Kanyakumari-629 165.Tamilnadu.India Department of Zoology Scott Christian College(Autonomous)NagercoilKanyakumari - 629 003.TamilnaduIndia Centre for Biodiversity and Biotechnology Department of BotanyN.M.Christian College.MarthandumKanyakumari - 629 165.TomilnaduIndia

Objective:To investigate the preliminary phytochemistry and antibacterial activity of the flower extract of Peltophorum ***:Phytochemical analysis was done by using the standard methods given by *** methanolic flower extract were tested against Escherichia coli,Klebsiella pneumonia,Pseudomonas *** aureus. Bacillus cereus,salmonella typhi,serratia marsecens,Acinetobacter *** sp., Proteus *** faecalis and streptococcus pyogenes by the agar disc diffusion ***:Preliminary phytochemical screening of flower extract showed the presence of phenolic compounds,***,steroids,tannins,xanthoproteic,carboxylic acids, coumarins and *** flower extract of Peltophorum pteroearpum showed significant activity against four gram positive(staphylococcus *** *** faecalis and streptococcus pyogenes) and three gram negative bacteria(Proteus mirabilis,Acinetohacter baumannii and serratia marsecens).out of 12 pathogenic bacteria ***:The findings of the present study confirm the presence of significant antibacterial activity against human pathogens in the flowers of Peltophorum pleracarpum.

关键词： Antibacterial activity Human pathogens Peltophorum pterocarpum Phytochemical screening

On the Contribution of Wu Wen-Tsün to Algebraic Topology

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Journal of systems science & Complexity 2019年第1期32卷 3-36页

作者： BRAssELET Jean-paul I2M (CNRs)-Aix-Marseille University

The aim of this article is to present the contribution of Wu Wen-Tsün to Algebraic Topology and more precisely to the theory of characteristic classes. several papers provide complete and welldocumented biography and academic career of Wu Wen-Tsün, in particular, Hudecek, 2014; O'Connor and Robertson, 2006; Wen-Tsün Wu's Academic Career, 2006; selected works of Wen-Tsun Wu, *** author does not repeat the details provided in these papers concerning the Wu Wen-Tsün's bibliography, we will just mention people involved in the Wu Wen-Tsün's period in *** addition to Wu Wen-Tsün's papers, the Dieudonné's book(Dieudonné, 1960) provides an excellent presentation of main results of Wu Wen-Tsün in Algebraic and Differential Topology. The author will use and abuse of this book(and refer to) when *** the introduction, the author recalls mainly historical facts concerning the contribution of Wu Wen-Tsün to Algebraic Topology. The second section shows speci?cally the contribution of Wu WenTsün to the stiefel-Whitney classes and introduces the third section, dealing with the(real) Wu *** author provides de?nition, properties as well as further developments and generalizations of the Wu classes. The fourth and ?fth sections are devoted to recent applications: In Cobordism theory and in Mathematical Physics. The author notices that Wu classes have been used as well in other domains,in particular surgery theory(Madsen and Milgram, 1979). The last section concerns the complex Wu classes and shows that the more recent Mather classes coincide with the previously de?ned complex Wu classes, that is a result from Zhou(1994)(see also Liu, 1996).This article is devoted to the contribution of Wu Wen-Tsün to the theory of Characteristic Classes,which coincides with his "French period"(1947–1951). However, speaking of Algebraic Topology, it is worthwhile to mention the important contribution of Wu Wen-Tsün to the Theory of realization of complexes or manifolds in Eucl

关键词： Algebraic topology characteristic class cobordism theory mathematical physics Wu Class

Active catalytic species generated in situ in zirconia incorporated hydrogen storage material magnesium hydride

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Journal of Magnesium and Alloys 2022年第3期10卷 852-861页

作者： D.Pukazhselvan K.s.sandhya Devaraj Ramasamy Aliaksandr shaula Igor Bdikin Duncan paul Fagg Department of Mechanical Engineering Nanoengineering Research GroupCentre for Mechanical Technology and Automation(TEMA)University of AveiroAveiro 3810-193Portugal Department of Chemistry Malankara Catholic CollegeKaliyakkavilaiTamil Nadu 629153India Department of Computational Biology and Bioinformatics University of KeralaThiruvananthapuramKerala 695581India UIDM ESTGPolytechnic Institute of Viana do CasteloViana do Castelo 4900Portugal

This study explores how zirconia additive interacts with MgH_(2)to improve its hydrogen storage *** it is confirmed that the zirconia added MgH_(2)powder releases hydrogen at a temperature of about 50℃below that of the additive free MgH_(2).subsequent tests by X ray diffraction(XRD)and infrared(IR)spectroscopy techniques reveal that the ZrO_(2) mixed MgH_(2)powder contains ZrHx(21.5)and MgO secondary *** observation is supported by the negative Gibbs free energy values obtained for the formation of ZrH_(2)/MgO from ZrO_(2)/MgH_(2)powder *** X ray photoelectron spectroscopy(XPs)study reveals that apart from Zr^(4+)cations,Zr^(2+) and zero valent Zr exist in the *** force microscopy(AFM)study reveals that the average grain size is 20 nm and the elemental line scan profiles further proves the existence of oxygen deficient Zr bearing phase(s).This study strengthens the belief that functional metal oxide additives in fact chemically interact with MgH_(2)to make active in-situ catalysts in the MgH_(2)system.

关键词： Hydrogen storage Binary hydrides Metal oxides Additives Nanocatalysis.

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一种适于碳纳米管制备的绿色前驱体(英文)

新型炭材料 2011年第2期26卷 85-88页

作者： s.paul s.K.samdarshi Department of Energy Tezpur University

根据绿色化学原理尝试探索一种合成多壁碳纳米管的天然可再生前驱体。应用化学气相沉积(CVD)法,采用一种天然可再生前躯体(椰仁油),通过系列步骤合成了MW CNTs。氮气既作为气化前驱体载气(气体流速:100mL/m in)又维持合成在惰性氛围中... 详细信息

根据绿色化学原理尝试探索一种合成多壁碳纳米管的天然可再生前驱体。应用化学气相沉积(CVD)法,采用一种天然可再生前躯体(椰仁油),通过系列步骤合成了MW CNTs。氮气既作为气化前驱体载气(气体流速:100mL/m in)又维持合成在惰性氛围中进行。合成的MW CNTs使用sEM、EDX、TEM和Ram an表征,最佳条件下得到的碳纳米管直径为80nm～90nm。

关键词：椰仁油天然可再生前躯体碳纳米管 CVD

自牺牲型金属有机框架衍生In_(2)s_(3)多级孔结构纳米材料强化光催化性能

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Chinese Journal of Catalysis 2024年第4期59卷 204-213页

作者：杨婷婷王彬朱剑豪夏杰祥李华明江苏大学化学化工学院能源研究院江苏镇江212013 香港城市大学物理系材料科学与工程系生物医学工程系中国香港

半导体基光催化是减少对化石燃料的依赖和解决环境污染问题的有前景的策略之一.在光催化有机污染物降解领域,硫化物材料备受关注.其中,In_(2)s_(3)催化剂因展现较好的催化活性及经济可行性,而被认为是光催化降解的理想催化剂之一.然而,... 详细信息

半导体基光催化是减少对化石燃料的依赖和解决环境污染问题的有前景的策略之一.在光催化有机污染物降解领域,硫化物材料备受关注.其中,In_(2)s_(3)催化剂因展现较好的催化活性及经济可行性,而被认为是光催化降解的理想催化剂之一.然而,采用传统煅烧法制备的In_(2)s_(3)催化剂由于比表面积小,暴露的活性位点有限,进而限制了其催化活性的进一步提升.因此,制备具有较大比表面积和多活性位点的In_(2)s_(3)基催化剂,对于推动光催化降解有机污染物领域的发展具有重要的意义.本文通过构建分级多孔结构的光催化剂,以增强材料的光吸收性能并优化光生载流子的迁移和分离,从而提升光催化降解有机污染物的性能.利用In基金属有机骨架(MOFs)作为自我牺牲模板,通过硫化制备了包括空心纳米管、微管、中空球和十二面体在内的多种分级In_(2)s_(3)光催化剂.分级多孔结构不仅增强了入射光的多次折射和反射,还提供了更大的表面积,从而提高了光生载流子的光利用率和相分离效率.实验结果表明,这些材料的光催化效率远高于块状和商用In_(2)s_(3).通过X射线光电子能谱、X射线衍射等手段验证了不同形貌分级多孔In_(2)s_(3)材料的成功制备.紫外-可见漫反射光谱结果表明,所有催化剂均可吸收部分可见光,结合莫特肖特基曲线和XPs价带谱结果,说明催化剂的导带、价带位置均满足光催化降解有机污染物的要求.光致发光光谱、光电流强度曲线和电化学阻抗曲线等研究表明,分级多孔结构有效促进了光生载流子的分离和迁移.光催化降解罗丹明B(RhB)和四环素(TC)性能评价结果表明,与块状和商用In_(2)s_(3)相比,具有分级多孔结构的In_(2)s_(3)材料表现出更好的光催化降解活性.其中,空心In_(2)s_(3)纳米管(HNTs)具有最佳的光催化性能,在光照1.5和2 h后,In_(2)s_(3)-HNT可以去除约50%的TC和95%的RhB,其RhB的降解速率分别是块状和商业In_(2)s_(3)的135.6倍和446.9倍,TC的降解速率分别是块状和商业级In_(2)s_(3)的7.8倍和36.5倍.电子顺磁共振和自由基捕获实验结果表明,在光催化降解过程中,空穴、超氧自由基以及单线态氧是主要的活性物种.特别是,当In_(2)s_(3)-HNT受到光照时,其独特的分级多孔结构使得光生电子和空穴对能够有效分离,这使得In_(2)s_(3)-HNT可以积累更多的活性氧自由基,从而显著提升了其光催化降解有机污染物的性能.综上,本文采用新型自牺牲模板法,制备了金属有机框架衍生In_(2)s_(3)多级孔结构纳米材料.通过精准调控In_(2)s_(3)催化剂的形貌,有效提升了光催化降解有机污染物性能.该方法在高效光催化剂的制备上展现了显著潜力,为设计高性能的光催化降解材料提供参考.

关键词：硫化铟金属有机框架形貌调控光催化污染物降解

Long-term survival of a patient with advanced pancreatic cancer under adjunct treatment with Viscum album extracts: A case report

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World Journal of Gastroenterology 2019年第12期25卷 1524-1530页

作者： paul G Werthmann Robert Kempenich Gerlinde Lang-Averous Gunver s Kienle Department of Methodology Institute for Applied Epistemology and Medical Methodology (IFAEMM) Center for Complementary Medicine Institute for Environmental Health Sciences and Hospital Infection Control Medical Center-University of Freiburg Private Praxis General Practitioner with Specialization in Oncology Department of Pathology Hopital de Hautepierre University Hospital of Strasbourg

BACKGROUND Advanced pancreatic cancer(aPC) has a poor prognosis with limited survival benefit from current standard treatment. Viscum album extracts(VAE) are used by many cancer patients, showing immune-stimulating effects, improved quality of life, and a survival benefit in patients with *** sUMMARY A 59-year-old architect developed epigastric pain. A cystic lesion of the pancreas of 45-mm diameter was detected. In a follow-up magnetic resonance imaging,about one year later, multiple lesions were seen in the corpus and the tail of the pancreas; CA-19-9 was elevated to 58.5 U/mL. A distal pancreatectomy with splenectomy was performed, and a tumor of 7 cm × 5 cm × 3.5 cm was *** investigation showed an intraductal papillary mucinous neoplasmassociated invasive adenocarcinoma with invasion of the lymph vessels,perineural invasion, and positive nodes(2/27); surgical margins showed tumor cells, and the tumor was classified as pT3 N1 M0 R1. The patient was treated with radiation of the tumor bed and capecitabine/oxaliplatin followed by gemcitabine and FOLFIRINOX. seven months after surgery, a liver metastasis was detected and treatment with FOLFIRINOX was started. Four months after detection of the metastasis, the patient opted for additional treatment with VAE. Another month later, the metastasis was treated with radiofrequency ablation(RFA). Eight months later, the hepatic lesion recurred and was again treated with RFA. Thecontinuous VAE treatment was increased in dose, and the patient stayed recurrence-free for the next 39 mo in good health and working full-time(as of the time this case report was written).CONCLUsION We present the case of a patient with aPC with R1-resection with development of liver metastasis during the course of treatment who showed an overall survival of 63 mo and a relapse-free survival of 39 mo under increasing VAE therapy. The possible synergistic effect on tumor control of RFA treatment and immunestimulatory effects of VAE

关键词： Pancreatic cancer Integrative medicine Viscum album extract Radiofrequency ablation Case report

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椰子油制炭微管

新型炭材料 2010年第5期25卷 325-328页

作者： s.paul s.K.samdarshi solar and Energy Materials Lab Department of EnergyTezpur University

报道了采用可再生的天然前驱体(椰子油),通过化学气相沉积制备一种"高长径比"的新型碳管结构,炭微管(CMTs)的方法。CMTs合成工艺:N2气氛,合成温度1175℃,流速100mL/min,二茂铁为催化剂。合成的CMTs利用sEM,EDX,TEM,和Raman光谱表征。结... 详细信息

报道了采用可再生的天然前驱体(椰子油),通过化学气相沉积制备一种"高长径比"的新型碳管结构,炭微管(CMTs)的方法。CMTs合成工艺:N2气氛,合成温度1175℃,流速100mL/min,二茂铁为催化剂。合成的CMTs利用sEM,EDX,TEM,和Raman光谱表征。结果表明:合成的CMTs的直径为1.7μm～2.1μm,并具有高的长径比。

关键词：炭微管化学气相沉积天然可再生前驱体

Enhancing Precision in Radiotherapy Delivery: Validating Monte Carlo simulation Models for 6 MV Elekta synergy Agility LINAC Photon Beam Using Two Models of the GAMOs Code

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World Journal of Nuclear science and Technology 2024年第2期14卷 146-163页

作者： Nogaye Ndiaye Oumar Ndiaye Papa Macoumba Faye Kodjo Joël Fabrice N’Guessan Djicknack Dione Khady sy Moussa Hamady sy Jean paul Latyr Faye Alassane Traoré Ababacar sadikhe Ndao Institute of Applied Nuclear Technology University Cheikh Anta Diop Dakar Senegal International Cancer Center of Dakar Dakar Senegal Department of Physics Faculty of Sciences and Technology University Cheikh Anta Diop Dakar Senegal

The most crucial requirement in radiation therapy treatment planning is a fast and accurate treatment planning system that minimizes damage to healthy tissues surrounding cancer cells. The use of Monte Carlo toolkits has become indispensable for research aimed at precisely determining the dose in radiotherapy. Among the numerous algorithms developed in recent years, the GAMOs code, which utilizes the Geant4 toolkit for Monte Carlo simula-tions, incorporates various electromagnetic physics models and multiple scattering models for simulating particle interactions with matter. This makes it a valuable tool for dose calculations in medical applications and throughout the patient’s volume. The aim of this present work aims to vali-date the GAMOs code for the simulation of a 6 MV photon-beam output from the Elekta synergy Agility linear accelerator. The simulation involves mod-eling the major components of the accelerator head and the interactions of the radiation beam with a homogeneous water phantom and particle information was collected following the modeling of the phase space. This space was po-sitioned under the X and Y jaws, utilizing three electromagnetic physics mod-els of the GAMOs code: standard, Penelope, and Low-Energy, along with three multiple scattering models: Goudsmit-saunderson, Urban, and Wentzel-VI. The obtained phase space file was used as a particle source to simulate dose distributions (depth-dose and dose profile) for field sizes of 5 × 5 cmsup>2sup> and 10 × 10 cmsup>2sup> at depths of 10 cm and 20 cm in a water phantom, with a source-surface distance (ssD) of 90 cm from the target. We compared the three electromagnetic physics models and the three multiple scattering mod-els of the GAMOs code to experimental results. Validation of our results was performed using the gamma index, with an acceptability criterion of 3% for the dose difference (DD) and 3 mm for the distance-to-agreement (DTA). We achieved agreements of 94% and 96%, respective

关键词： GAMOs Monte Carlo LINAC Radiotherapy Dose Distribution Phase space Gamma Index 6 MV Photon Beam