检索结果-南通市图书馆

China Foundry 2024年第4期21卷 379-386页

作者： Yang Liao Ye-yuan Hu Kosuke Ikeda ryoji Okabe Rui-fen Wu Ryota Ozaki Qing-yan Xu Key Laboratory for Advanced Materials Processing Technology School of Materials Science and EngineeringTsinghua UniversityBeijing 100084China Composite Laboratory Research&Innovation Center Mitsubishi Heavy Industries Ltd.Nagasaki 8510392Japan

Polypropylene is commonly used as a binder for ceramic injection molding,and rapid cooling is often encountered during ***,the crystallization behavior of polypropylene shows a strong dependence on cooling rate due to its semi-crystalline ***,the influence of cooling rate on the quality of final product cannot be *** this study,the fast differential scanning calorimetry(FSC)test was performed to study the influence of cooling rate on the non-isothermal crystallization behavior and non-isothermal crystallization kinetics of a copolymer polypropylene(PP BC03B).The results show that the crystallization temperatures and crystallinity decrease as the cooling rate *** addition,two exothermic peaks occur when cooling rate ranges from 30 to 300 K·s^(-1),indicating the formation of another crystal ***,Ozawa and Mo equations were used to explore the non-isothermal crystallization kinetics,and it can be concluded that the Mo method is suitable for this study.

关键词： cooling rate crystallization temperature crystallinity non-isothermal crystallization kinetics FSC copolymer polypropylene

Expression levels of K_(ATP)channel subunits and morphological changes in the mouse liver after exposure to radiation

在线全文

学校读者我要写书评

暂无评论

World Journal of Experimental Medicine 2024年第2期14卷 103-113页

作者： Ming Zhou Tao-Sheng Li Hiroshi Abe Hideo Akashi ryoji Suzuki Yoshio Bando Department of Anatomy Akita University Graduate School of MedicineAkita 010-8543Japan Department of Stem Cell Biology Atomic Bomb Disease InstituteNagasaki UniversityNagasaki 852-8523Japan Sendai Old Age Refresh Station A Long-term Care Health FacilitySendai 981-1105Japan

BACKGROUND ATP sensitive K+(K_(ATP))channels are ubiquitously distributed in various of cells and tissues,including the *** play a role in the pathogenesis of myocardial and liver *** To evaluate the radiation-induced changes in the expression of K_(ATP)channel subunits in the mouse liver to understand the potential role of K_(ATP)channels in radiation *** Adult C57BL/6 mice were randomly exposed toγ-rays at 0 Gy(control,n=2),0.2 Gy(n=6),1 Gy(n=6),or 5 Gy(n=6).The livers were removed 3 and 24 h after radiation *** and eosin staining was used for morphological observation;immunohistochemical staining was applied to determine the expression of K_(ATP)channel subunits in the liver *** Compared with the control group,the livers exposed to 0.2 Gyγ-ray showed an initial increase in the expression of Kir6.1 at 3 h,followed by recovery at 24 h after *** to a high dose of 5.0 Gy resulted in decreased expression of Kir6.1 and increased expression of SUR2B at 24 ***,the expression of Kir6.2,SUR1,or SUR2A had no remarkable changes at 3 and 24 h after exposure to any of these *** The expression levels of Kir6.1 and SUR2B in mouse liver changed differently in response to different radiation doses,suggesting a potential role for them in radiation-induced liver injury.

关键词： Radiation exposure ATP-sensitive K^(+)channel Mouse Liver

Progress in reducing AC magnetization losses of Bi2223/Ag tapes by introducing interfilamentary oxide barriers

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Progress in Natural Science:Materials International 2010年第1期20卷 104-110页

作者： ryoji INADA Akio OOTA Toyohashi University of Technology 1-1 HibarigaokaTempaku-choToyohashiAichi 441-8580Japan

This paper presents our recent progress for the development of low-loss Bi2223/Ag tapes with interfilamentary oxide *** the compatibility with Bi2223 superconductors,SrZrO3was selected as barrier ***,small amount of Bi2212 was mixed with SrZrO3to improve its ductility for cold *** controlling the thickness of barrier layers among the filaments,reducing the tape width（<3 mm）and twisting the filaments tightly（<5 mm in twist pitch lengths）,coupling frequency fcexceeded 250 Hz even in an AC perpendicular field at *** Jcof the barrier tapes with tightly twisted filaments was in the range of 12-15 kA/cm2at 77 K and *** 50 mT and 50 Hz,the twisted barrier tapes showed 60%-70%lower perpendicular field losses than the conventional 4 mm-width tape with fully coupled filaments.

关键词： Bi2223 tapes interfilamentary oxide barriers filament twisting magnetization losses coupling frequency

Enhancement of Antitumor Effect of Tegafur/Uracil(UFT) plus Leucovorin by Combined Treatment with Protein-Bound Polysaccharide,PSK,in Mouse Models

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Cellular & Molecular Immunology 2007年第4期4卷 295-299页

作者： ryoji Katoh Mitsuru Ooshiro Department of Surgery Toho University Sakura Medical CenterSakura-shiChibaJapan

We evaluated the antitumor effect of combined therapy with tegafur/uracil （UFT） plus leucovorin （LV）（UFT/LV） and protein-bound polysaccharide, PSK, in three mouse models of transplantable tumors. UFT/LV showed antitumor effect against Meth A sarcoma, and the antitumor effect was enhanced when PSK given concomitantly. UFT/LV showed antitumor effect to Lewis lung carcinoma and PSK alone also showed antitumor effect at high dose, but a combination of UFT/LV and PSK resulted in no enhanced antitumor effect. Colon 26 carcinoma was weakly responsive to UFT/LV, and no enhancement of antitumor effect was found even PSK was used in combination. In conclusion, while the effect of PSK varies depending on tumor, combined use of UFT/LV and PSK may be expected to augment the antitumor effect.

关键词： UFF leucovorin PSK Meth A Lewis lung carcinoma colon 26 antitumor effect

Stem cell therapy for central nerve system injuries: glial cells hold the key

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2014年第13期9卷 1253-1260页

作者： Li Xiao Chikako Saiki ryoji Ide Pharmacology Department The Nippon Dental University School of Life Dentistry at Tokyo Tokyo Japan Physiology Department The Nippon Dental University School of Life Dentistry at Tokyo Tokyo Japan

Mammalian adult central nerve system （CNS） injuries are devastating because of the intrinsic difficulties for effective neuronal regeneration. The greatest problem to be overcome for CNS recovery is the poor regeneration of neurons and myelin-forming cells, oligodendrocytes. Endogenous neural progenitors and transplanted exogenous neuronal stem cells can be the source for neuronal regeneration. However, because of the harsh local microenvironment, they usually have very low efficacy for functional neural regeneration which cannot compensate for the loss of neurons and oligodendrocytes. Glial cells （including astrocytes, microglia, oligodendrocytes and NG2 glia） are the majority of cells in CNS that provide support and protection for neurons. Inside the local microenvironment, glial cells largely influence local and transplanted neural stem cells survival and fates. This review critically analyzes current finding of the roles of glial cells in CNS regeneration, and highlights strategies for regulating glial cells＇ behavior to create a permissive microenvironment for neuronal stem cells.

关键词： Neuron regeneration stem cell therapy glial cells microenvironment oligodendrocyteregeneration CNS injury

Current advances in humanized mouse models

在线全文

学校读者我要写书评

暂无评论

Cellular & Molecular Immunology 2012年第3期9卷 208-214页

作者： ryoji Ito Takeshi Takahashi Ikumi Katano Mamoru Ito Central Institute for Experimental Animals Kawasaki Japan

Humanized mouse models that have received human cells or tissue transplants are extremely useful in basic and applied human disease research. Highly immunodeficient mice, which do not reject xenografts and support cell and tissue differentiation and growth, are indispensable for generating additional appropriate models. Since the early 2000s, a series of immunodeficient mice appropriate for generating humanized mice has been successively developed by introducing the IL-2Rynull gene （e.g., NOD/SCID/7c＂uu and Rag2nu＂ycnun mice）. These strains show not only a high rate of human cell engraftment, but also generate well-differentiated multilineage human hematopoietic cells after human hematopoietic stem cell （HSC） transplantation. These humanized mice facilitate the analysis of human hematology and immunology in vivo. However, human hematopoietic cells developed from HSCs are not always phenotypically and functionally identical to those in humans. More recently, a new series of immunodeficient mice compensates for these disadvantages. These mice were generated by genetically introducing human cytokine genes into NODISCIDI？cn＂u and Rag2nulITcnUll mice. In this review, we describe the current knowledge of human hematopoietic cells developed in these mice. Various human disease mouse models using these humanized mice are summarized.

关键词： animal model immunodeficient mice immunology hematology humanized mice

Properties of garnet-type Li6La3ZrTaO12 solid electrolyte films fabricated by aerosol deposition method

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Progress in Natural Science:Materials International 2017年第3期27卷 350-355页

作者： ryoji Inada Takayuki Okada Akihiro Bando Tomohiro Tojo Yoji Sakurai Department of Electrical and Electronic Information Engineering Toyohashi University of Technology

The garnet-type Li6La3ZrTaO12（LLZT） solid electrolyte films were fabricated by aerosol deposition（AD）***-milled LLZT powder with a cubic garnet structure and a particle size of 1-2 urn was used as raw material and deposited directly on a SUS316L or a glass substrate via impact ***-deposited LLZT film has a cubic garnet structure but contains Li2CO3and *** observation revealed that the film consists of LLZT particles fractured into submicron *** impurity phase formation during AD process was caused by the local heating by the collision between LLZT particles and deposition surface and reaction with *** Li+ion conductivity of LLZT film was estimated to be 0.24 × 10-5S cm-1at room *** conductivity of LLZT film was confirmed to be around 10-12S cm-1,indicating the dominant Li+ion conduction of LLZT film.

关键词： Lithium-ion Garnet Solid electrolyte Thick film Aerosol deposition Ionic conductivity

Self-interstitials generated on silicon bulk surface

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Progress in Natural Science:Materials International 2011年第1期21卷 17-20页

作者： Yukihiro KATO ryoji FUKUDA Yuta TAKENO Toshitada SHIMOZAKI Takahisa OKINO Department of Design Engineering Semiconductor Business DivisionMitsumi Electric Co.LtdAtugi 243-0004Japan Department of Architecture and Mechatronics Faculty of EngineeringOita UniversityOita 870-1192Japan Department of Materials and Technology Kyushu Institute of TechnologyKitakyushu 804Japan

The self-interstitial atoms in silicon generated by the bulk surface oxidation diffuse into the bulk inside and affect the phenomena such as the diffusions and the stacking *** generation rate of self-interstitials(Rgen) depends on theωpower of the oxidation film growth rate dX0/*** physical quantityωis important to understand the material science relevant to self-interstitials in the silicon ***,the conclusiveωvalue is not reported,although variousωvalues to control the generation rate have been *** the present study,the chemical reaction equation is analytically solved,and using the result,the oxidation stacking fault radius(r) is analytically expressed against the oxidation time(t).Comparing the obtained relation of r=r(t) with the experimental results of the stacking faults,the analytical expression of co is determined and the physical meaning ofωis ***,the temperature dependence ofωis also numerically determined.

关键词： silicon self-interstitial vacancy oxide impurity diffusion stacking fault

Overspeeding characteristics of turbomachinery for gas generator cycle air turbo ramjet engine

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Propulsion and Power Research 2022年第4期11卷 444-456页

作者： ryojiro Minato Daisuke Nakata Masaharu Uchiumi ryoji Imai Kazuyuki Higashino Department of Engineering Muroran Institute of Technology MuroranHokkaido050-8585Japan Aerospace Plane Research Center Muroran Institute of Technology MuroranHokkaido050-8585Japan

The main interest in the current study focuses on the possibility of overspeeding for the gas-generator cycle air turbo ramjet(GG-ATR)*** authors developed the air turbo ramjet engine and investigated its compressor *** on those data,the authors developed the analytical code for the air turbo ramjet engine,which calculates the performances of turbomachinery,gas-generator,and ram *** previous study described that the rotor overspeeding would not occur in the air turbo rocket ***,the current results show that degraded ram combustion can decrease the compressor pressure ratio and the compressor *** reduced compressor power can cause overspeeding for the air turbo ramjet *** experimental results of compressor power and turbine inlet pressure support those analytical results.

关键词： Air turbo ramjet engine Compressor map Overspeeding Combustion efficiency

Enzyme-digested Colla Corii Asini(E’jiao) prevents hydrogen peroxide-induced cell death and accelerates amyloid beta clearance in neuronal-like PC12 cells

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2020年第12期15卷 2270-2277页

作者： Li Xiao Feng Liao ryoji Ide Tetsuro Horie Yumei Fan Chikako Saiki Nobuhiko Miwa Department of Pharmacology The Nippon Dental UniversitySchool of Life Dentistry at TokyoTokyoJapan National Engineering Research Center for Gelatin-based Traditional Chinese Medicine Dong-E-E-Jiao Co.Ltd.LiaochengShandong ProvinceChina Department of Physiology The Nippon Dental UniversitySchool of Life Dentistry at TokyoTokyoJapan Research Center The Nippon Dental UniversitySchool of Life Dentistry at TokyoTokyoJapan Department of Life Sciences Prefectural University of HiroshimaHiroshimaJapan

As an aging-associated degenerative disease,Alzheimer’s disease is characterized by the deposition of amyloid beta(Aβ),oxidative stress,inflammation,dysfunction and loss of cholinergic *** Corii Asini(CCA)is a traditional Chinese medicine which has been used for feebleness-related diseases and *** might delay aging-induced degenerative changes in *** the present study,we evaluated antioxidant activity,cytoprotective effects,and Aβremovability of enzyme-digested Colla Corii Asini(CCAD).Oxygen radical absorbance capacity(ORAC)activity assay showed that,as compared to gelatins from the skin of porcine,bovine and cold water fish,CCA exhibited the highest ORAC *** ORAC activity of CCA and CCAD was increased gradually by the length of time in *** analysis by scanning electron microscopy showed that among CCA manufactured in 2008,2013,2017 and gelatin from cold water fish skin,CCA manufactured in 2008 presented the smoothest surface *** further tested the protective effects of CCAD(manufactured in 2008)and enzyme-digested gelatin from cold water fish skin(FGD)on hydrogen peroxide(H2O2)-induced cell death in nerve growth factor-differentiated neuronal-like PC12 *** blue assay showed that both FGD and CCAD at 0.5 mg/m L increased cell viability in H2O2-treated neuronal-like PC12 *** protection of CCAD was significantly superior to that of ***(Ach E)assay showed that both FGD and CCAD inhibited Ach E activity in nerve growth factor-differentiated neuronal-like PC12 cells to 89.1%and 74.5%of that in non-treated cells,*** data suggest that CCAD might be able to increase the neurotransmitter *** CCAD inhibited Ach E activity in neuronal-like PC12 cells,CCAD prevented H2O2-induced abnormal deterioration of Ach *** and neprilysin activity assay results indicated that CCAD reduced amyloid beta accumulation and increased neprilysin activity in Aβ1–

关键词： acetylcholinesterase activity Alzheimer’s disease amyloid beta clearance antioxidant Colla Corii Asini collagen neuroprotection PC12 cells