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Dissecting genetic diversity and genomic background of Petunia cultivars with contrasting growth habits

Horticulture Research 2020年第1期7卷 634-648页

作者： Yufang Guo ryan M.Warner Department of Horticulture Michigan State UniversityEast LansingMI 48824USA

The cultivated petunia(Petunia×hybrida)is derived from the progenitor species *** and *** hybridization dates back only to the 1830s,though intensive breeding efforts have yielded cultivars exhibiting incredible diversity for many traits,including growth habit,flower color,and flower *** now,little is known about the genetic diversity and genomic background of modern *** we selected a panel of 13 cultivars with contrasting growth habits and three wild species(the progenitors and ***)to estimate the genomic contribution from the ancestral species and to study whether the variation of the genetic origin could be associated with different breeding programs or morphological *** sequencing identified 1,164,566 SNPs representing 98.4%(32,451)of the transcripts that cover 99.2%(of 52,697,361 bp)of the *** *** with an upright growth habit had more homozygous alleles and more ***-derived alleles than trailing cultivars,while mounded cultivars had intermediate *** previous studies,we found the proportions of alleles derived from each progenitor species varied across cultivars but overall were not biased toward one progenitor species,suggesting diverse selection during cultivar *** trailing cultivars,alleles potentially introgressed from other wild species(“out”alleles)were ***“out”alleles were clustered in particular regions of chromosomes,suggesting that these regions may be hotspots of *** in these regions were enriched with gene ontology terms associated with growth *** study provides novel insight into the contributions of progenitor species to the genomic background of modern petunia cultivars and identifies genome regions that may harbor genes conferring the trailing growth habit for further exploration.

关键词： cultivar breeding trail

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Measurement of bullet impact conditions using automated in-flight photography system

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Defence Technology（防务技术） 2017年第4期13卷 288-294页

作者： ryan Decker Marco Duca Shawn Spickert-Fulton Armament Research Design and Engineering Center 94 Ramsey Avenue Picatinny Arsenal NJ 07806 USA

Knowledge of impact conditions is critical to evaluating the terminal impact performance of a *** a small caliber bullet,in-flight velocity has been precisely measured for decades using detection screens,but accurately quantifying the orientation of the bullet on a target has been more *** report introduces the Automated Small-Arms Photogrammetry(ASAP)analysis method used to measure,model,and predict the orientation of a small caliber bullet before reaching an impact *** uses advanced hardware developed by Sydor Technologies to record a series of infrared digital *** images(four orthogonal pairs)are processed using computer vision algorithms to quantify the orientation of the projectile and re-project its precise position and orientation into a three-dimensional muzzle-fixed coordinate *** epicyclic motion model is fit to the measured data,and the epicyclic motion is extrapolated to the target *** results are fairly immediate and may be reviewed during ***-out demonstrations have shown that the impact-angle prediction capability is less than six hundredths of a degree for the 5.56 mm ball round ***:Yaw,Terminal ballistics,Exterior ballistics,Test&evaluation,Computer vision,Image processing,Angle of

关键词： Terminal ballistics Exterior ballistics Test & evaluation Computer vision Image processing Angle of attack

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Towards full predictions of temperature dynamics in McNary Dam forebay using OpenFOAM

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Water Science and Engineering 2013年第3期6卷 317-330页

作者： Yu-Shi WANG Marcela POLITANO ryan LAUGHERY IIHR-Hydroscience and Engineering The University of Iowa Iowa City U.S. Army Corps of Engineers Walla Walla District Walla Walla

Hydroelectric facilities impact water temperature; low velocities in a reservoir increase residence time and enhance heat exchange in surface layers. In this study, an unsteady three-dimensional model was developed to predict the temperatm＇e dynamics in the McNary Dam forebay. The model is based on the open-source code OpenFOAM. RANS equations with the Boussinesq approximation were used to solve the flow field. A： realizable k-ε model that accounts for the production of wind turbulence was developed. Solar radiation and convective heat transfer at the free surface were included. The result of the model was compared with the field data collected on August 18, 2004. Changes in diurnal stratification were adequately predicted by the model. Observed vertical and lateral temperature distributions were accurately captured. Results indicate that the model can be used as a numerical tool to assess structural and operational alternatives to reduce the forebay temperature.

关键词： three-dimensional numerical simulation," water temperature," reservoir," thermal dynamics OpenFOAM McNary Dam forebay

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CONVERGENCE AND OPTIMALITY OF ADAPTIVE MIXED METHODS FOR POISSON’S EQUATION IN THE FEEC FRAMEWORK

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Journal of Computational Mathematics 2020年第5期38卷 748-767页

作者： Michael Holst Yuwen Li Adam Mihalik ryan Szypowski Department of Mathematics University of CaliforniaSan DiegoCA 92123USA Department of Mathematics and Statistics Cal Poly PomonaUSA

Finite Element Exterior Calculus (FEEC) was developed by Arnold, Falk, Winther andothers over the last decade to exploit the observation that mixed variational problems canbe posed on a Hilbert complex, and Galerkin-type mixed methods can then be obtained bysolving finite-dimensional subcomplex problems. Chen, Holst, and Xu (Math. Comp. 78(2009) 35–53) established convergence and optimality of an adaptive mixed finite elementmethod using Raviart–Thomas or Brezzi–Douglas–Marini elements for Poisson’s equationon contractible domains in R^2, which can be viewed as a boundary problem on the deRham complex. Recently Demlow and Hirani (Found. Math. Comput. 14 (2014) 1337–1371) developed fundamental tools for a posteriori analysis on the de Rham *** this paper, we use tools in FEEC to construct convergence and complexity resultson domains with general topology and spatial dimension. In particular, we construct areliable and efficient error estimator and a sharper quasi-orthogonality result using a noveltechnique. Without marking for data oscillation, our adaptive method is a contractionwith respect to a total error incorporating the error estimator and data oscillation.

关键词： Finite Element Exterior Calculus Adaptive finite element methods A posteriori error estimates,Convergence Quasi-optimality

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Modern treatment strategies for penile prosthetics in Peyronie’s disease:a contemporary clinical review

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Asian Journal of Andrology 2020年第1期22卷 51-59页

作者： Matthew J Ziegelmann M ryan Farrell Laurence A Levine Division of Urology Rush University Medical CenterChicagoIL 60612USA

Peyronie's disease is a common condition resulting in penile deformity,psychological bother,and sexual *** dysfunction is one common comorbid condition seen in men with Peyronie’s disease,and its presence significantly impacts treatment *** a man with Peyronie's disease and significant erectile dysfunction who desires the most reliable treatment,penile prosthesis placement should be strongly *** some instances,such as those patients with relatively mild curvature,prosthesis placement alone may result in adequate ***,many patients will require additional straightening maneuvers such as manual modeling,penile plication,and tunica albuginea incision with or without *** patients with severe penile shortening,penile length restoration techniques may also be ***,we provide a comprehensive clinical review of penile prosthesis placement in men with Peyronie's ***,we discuss preoperative indications,intraoperative considerations,adjunctive straightening maneuvers,and postoperative outcomes.

关键词： collagenase grafting penile length penile prosthesis Peyronie's

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Alzheimer’s disease:a tale of two diseases?

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Neural Regeneration Research 2021年第10期16卷 1958-1964页

作者： Eleonora Nardini ryan Hogan Anthony Flamier Gilbert Bernier Whitehead Institute for Biomedical Research CambridgeMAUSA Stem Cell and Developmental Biology Laboratory Hôpital Maisonneuve-RosemontMontrealQCCanada Department of Neurosciences University of MontrealMontrealQCCanada

Sporadic late-onset Alzheimer’s disease(SLOAD)and familial early-onset Alzheimer’s disease(FEOAD)associated with dominant mutations in APP,PSEN1 and PSEN2,are thought to represent a spectrum of the same disorder based on near identical behavioral and histopathological ***,FEOAD transgenic mouse models have been used in past decades as a surrogate to study SLOAD pathogenic mechanisms and as the gold standard to validate drugs used in clinical ***,such research has yielded little output in terms of therapeutics targeting the disease’s development and *** this short review,we interrogate the widely accepted view of one,dimorphic disease through the prism of the Bmi1+/–mouse model and the distinct chromatin signatures observed between SLOAD and FEOAD brains.

关键词： aging Alzheimer’s disease BMI1 epigenetics familial late-onset sporadic

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Numerical Diffusion Control of a Space-Time Discontinuous Galerkin Method

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Communications in Computational Physics 2009年第2期5卷 469-483页

作者： Michel Borrel Juliette ryan ONERA BP72-29 Avenue de la Division Leclerc92322Chatillon CedexFrance

Variations on space-time Discontinuous Galerkin(STDG)discretization associated to Runge-Kutta schemes are *** new schemes while keeping the original scheme order can improve accuracy and *** analysis is made on academ... 详细信息

关键词： Gas dynamics aeroacoustics discontinuous Galerkin discretization Runge-Kutta schemes numerical diffusion control

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Measuring absolute adsorption in porous rocks using oscillatory motions of a spring-mass system

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Chinese Journal of Chemical Engineering 2022年第4期35卷 131-139页

作者： Younki Cho ryan Lo Keerthana Krishnan Xiaolong Yin Hossein Kazemi Petroleum Engineering Colorado School of MinesGoldenCO 80401USA

We present an oscillation-based method to measure absolute adsorption,or total gas,contained in porous rocks without and with excess *** conducted with a macroporous Berea sandstone sample in nitrogen where excess adsorption is negligible show that absolute adsorption can be obtained after the added mass of co-accelerated gas outside the sample is *** experiments conducted in propane with a crushed Niobrara shale sample with micro-and mesopores,absolute adsorption included significant excess *** subtracting both the added mass outside the sample and the gas that would be in the sample assuming no excess adsorption existed,estimated excess adsorption of propane is in good agreement with that projected based on capillary condensation of propane in the volume of mesopores.

关键词： Adsorption Porous media Shale Capillary condensation Oscillation

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A bayesian optimisation methodology for the inverse derivation of viscoplasticity model constants in high strain-rate simulations

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Defence Technology（防务技术） 2022年第9期18卷 1563-1577页

作者： Shannon ryan Julian Berk Santu Rana Brodie McDonald Svetha Venkatesh Applied Artificial Intelligence Institute(A^(2)I^(2)) Deakin University75 Pigdons RdWaurn PondsVIC3216Australia Defence Science and Technology Group 506 Lorimer StreetFishermans BendVIC3207Australia

We present an inverse methodology for deriving viscoplasticity constitutive model parameters for use in explicit finite element simulations of dynamic processes using functional experiments, i.e., those which provide value beyond that of constitutive model development. The developed methodology utilises Bayesian optimisation to minimise the error between experimental measurements and numerical simulations performed in LS-DYNA. We demonstrate the optimisation methodology using high hardness armour steels across three types of experiments that induce a wide range of loading conditions: ballistic penetration, rod-on-anvil, and near-field blast deformation. By utilising such a broad range of conditions for the optimisation, the resulting constitutive model parameters are generalised, i.e., applicable across the range of loading conditions encompassed the by those experiments(e.g., stress states, plastic strain magnitudes, strain rates, etc.). Model constants identified using this methodology are demonstrated to provide a generalisable model with superior predictive accuracy than those derived from conventional mechanical characterisation experiments or optimised from a single experimental condition.

关键词： Constitutive modelling Finite element Bayesian optimisation Finite element model updating

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A Multi-Flow Information Flow Tracking Approach for Proving Quantitative Hardware Security Properties

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Tsinghua Science and Technology 2021年第1期26卷 62-71页

作者： Yu Tai Wei Hu Lu Zhang Dejun Mu ryan Kastner the School of Cybersecurity Northwestern Polytechnical UniversityXi'an 710072China the School of Automation Northwestern Polytechnical UniversityXi'an 710072China the Department of Computer Science and Engineering University of CaliforniaSan DiegoCA 92093USA

Information Flow Tracking(IFT)is an established formal method for proving security properties related to confidentiality,integrity,and *** has seen promise in identifying security vulnerabilities resulting from design flaws,timing channels,and hardware Trojans for secure hardware ***,existing IFT methods tend to take a qualitative approach and only enforce binary security properties,requiring strict non-interference for the properties to hold while real systems usually allow a small amount of information flows to enable desirable ***,existing methods are inadequate for reasoning about quantitative security properties or measuring the security of a design in order to assess the severity of a security *** this work,we propose two multi-flow solutions—multiple verifications for replicating existing IFT model and multi-flow IFT *** proposed multi-flow IFT method provides more insight into simultaneous information flow behaviors and allows for proof of quantitative information flow security properties,such as diffusion,randomization,and boundaries on the amount of simultaneous information *** results show that our method can be used to prove a new type of information flow security property with verification performance benefits.

关键词： hardware security Information Flow Tracking(IFT) multi-flow IFT security property

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