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Neuroprotective potential for mitigating ischemia-reperfusion-induced damage

Neural Regeneration Research 2025年第8期20卷 2199-2217页

作者： Zi Ye runqing liu Hangxing Wang Aizhen Zuo Cen Jin Nan Wang Huiqi Sun Luqian Feng Hua Yang The Clinical Medical College Guizhou Medical UniversityGuiyangGuizhou ProvinceChina Division of Infectious Diseases Department of Internal MedicinePeking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina School of Medical Imaging Guizhou Medical UniversityGuiyangGuizhou ProvinceChina Division of Gastroenterology First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenan ProvinceChina The Second Clinical Medical College Lanzhou UniversityLanzhouGansu ProvinceChina Department of Neurosurgery Affiliated Hospital of Guizhou Medical UniversityGuiyangGuizhou ProvinceChina

Reperfusion following cerebral ischemia causes both structural and functional damage to brain tissue and could aggravate a patient's condition;this phenomenon is known as cerebral ischemia-reperfusion *** studies have elucidated the neuroprotective role of the sirtuin protein family(Sirtuins)in modulating cerebral ischemia-reperfusion ***,the potential of utilizing it as a novel intervention target to influence the prognosis of cerebral ischemia-reperfusion injury requires additional *** this review,the origin and research progress of Sirtuins are summarized,suggesting the involvement of Sirtuins in diverse mechanisms that affect cerebral ischemia-reperfusion injury,including inflammation,oxidative stress,blood-brain barrier damage,apoptosis,pyroptosis,and *** therapeutic avenues related to Sirtuins that may improve the prognosis of cerebral ischemia-reperfusion injury were also investigated by modulating Sirtuins expression and affecting representative pathways,such as nuclear factor-kappa B signaling,oxidative stress mediated by adenosine monophosphate-activated protein kinase,and the forkhead box *** review also summarizes the potential of endogenous substances,such as RNA and hormones,drugs,dietary supplements,and emerging therapies that regulate Sirtuins *** review also reveals that regulating Sirtuins mitigates cerebral ischemia-reperfusion injury when combined with other risk *** Sirtuins show promise as a potential target for the treatment of cerebral ischemiareperfusion injury,most recent studies are based on rodent models with circadian rhythms that are distinct from those of humans,potentially influencing the efficacy of Sirtuinstargeting drug ***,this review provides new insights into the role of Sirtuins in the pathology and treatment of cerebral ischemia-reperfusion injury.

关键词： apoptosis autophagy blood-brain barrier dietary supplements drug hormones inflammation neuroprotection oxidative stress prognosis pyroptosis reperfusion injury risk factors RNA therapeutics

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Prediction of Antifrccze Critical Strength of Infant Age Concrete

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Journal of Wuhan University of Technology(Materials Science) 2008年第2期23卷 272-275页

作者： liu Jun liu runqing School of Civil ＆ Hydraulic Engineering Dalian University of Technology Dalian 116024 Liaoning School of Materials Science and Engineering Shenyang Jianzhu University Shenyang 110168 Liaoning

The rule of infant age concrete strength development under low temperature and complex affecting factors is researched. An efficient and reliable mathematical forecast model is set up to predict the infant age concrete antifreeze critical strength under low temperature at construction site. On the basis of the revision of concrete equivalent coefficient under complex influencing factors, least-squares curve-fitting method is applied to approximate the concrete strength under standard curing and the forecast formula of concrete compressive strength could be obtained under natural temperature condition by various effects. When the amounts of double-doped are 10% fly ashes and 4% silica fumes as coment replacement, the antifreeze critical strength changes form 3.5-4.1MPa under different low temperature curing. The equivalent coefficient correction formula of concrete under low temperature affected by various factors could be obtained. The obtained equivalent coefficient is suitable for calculating the strength which is between 10% to 40% of standard strength and the curing temperature from 5-20 ℃. The forecast value of concrete antifreeze critical strength under low temperature could be achieved by combining the concrete antifreeze critical strength value with the compressive strength forecast of infant age concrete under low temperature. Then the theory for construction quality control under low temperature is provided.

关键词： low temperature concrete infant age equivalent coefficient least-squares curve-fitting strength prediction

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A Summary of the Forum on Language Learning Theory——Editing Board of Chinese Teaching in the World Editing Board of Applied Linguistics Editing Board of Language Teaching and Linguistic Studies

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世界汉语教学 1992年第4期6卷 246-260页

作者： Zhang Wangxi, liu runqing

1. Participants Initiated by Lü Bisong from Beijing Language Institute and sponsored by the Editing Boardsof Chinese Teaching in the World, Applied Linguistics, and Language Teaching and LinguisticStudies, a forum on language learning theory was held from May 14 to 18, 1992 in Beijing, in or-der to push forward China’s research in language teaching theories and language teaching method-ology. The suggested areas for discussion at the Forum included: 1. the scope of research in lan-guage learning theory; 2. significance of these theories for language teaching; 3. relation and dif-ference between "learning" and "acquisition" ; 4. similarities and differences between L1 and L2learning; 5. relation between spoken language and written language; 6. research methods in lan-guage learning theory; 7. the state of the art of this research in other countries; 8. the state ofthe art in China; 9. direction and focus in China’s research in the field;10. the future of this re-

关键词：汉语教学世界内功习得责任编辑学得学习获得掌握

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Study on the flotation technology and adsorption mechanism of galena–jamesonite separation

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International Journal of Mining Science and Technology 2015年第1期25卷 53-57页

作者： Sun Wei Han Haisheng Tao Hongbiao liu runqing School of Minerals Processing & Bioengineering Central South University

In order to further separate the concentrate containing galena and jamesonite before undergoing hydrometallurgical process, flotation experiment was performed on the basis of mineralogical *** the adsorption mechanisms of collector H on galena and jamesonite were also studied by FT-IR spectra analysis and molecular dynamics(MD) simulation. The flotation result shows that the efficient separation can be achieved with H as selective collector. Galena concentrated with Pb grade of 72.09%and Pb recovery of 50.96% was obtained, and jamesonite concentrated with Sb grade and recovery of10.89% and 76.67% respectively was obtained as well. Infrared spectrum analysis indicates that collector H can adsorb on the surface of galena and react with Pb2+to generate hydrophobic salt, while no evident adsorption phenomenon was observed on the surface of jamesonite. The MD simulation and calculation results demonstrate that adsorption energy of collector H on galena and jamesonite surface is à872.74 k J/mol and à500.538 k J/mol, respectively, which means collector H is easier to adsorb on the surface of galena than that of jamesonite.

关键词： Mixed concentrationGalena JamesoniteFlotationMolecular dynamic simulationAdsorption energy

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Surface chemical study of the selective separation of chalcopyrite and marmatite

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Mining Science and Technology 2010年第4期20卷 542-545页

作者： liu runqing SUN Wei HU Yuehua WANG Dianzuo School of Minerals Processing and Bio-engineering Central South UniversityChangsha 410083China

FCLS (Ferric Chromium Lignin Sulfonate) was used to aid the separation of chalcopyrite from marmatite. Flotation, adsorption and zeta-potential tests of treated marmatite and chalcopyrite were performed. The flotation of marmatite was strongly depressed, while that of chalcopyrite was only slightly depressed, over a wide range of pH values when FCLS was used as depressant in the presence of Butyl Xanthate (BX). The adsorption of BX onto chalcopyrite or marmatite takes place over a wide pH range. The adsorption density of BX on chalcopyrite and marmatite decreases as the pH increases. The adsorption density of FCLS onto marmatite is greater than the adsorption density onto chalcopyrite. The zeta potentials of chalcopyrite and marmatite become more negative due to the addition of xanthate and FCLS.

关键词： flotation depressant sulfide ore froth flotation

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Using pectin to separate talc and molybdenite through the surface modification with Cu^(2+):Applications and mechanism

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International Journal of Mining Science and Technology 2023年第3期33卷 363-377页

作者： Changtao Wang Qilin Zhai runqing liu Meirong Wu Wei Sun Nianwen Jing Feifei Xie School of Minerals Processing and Bioengineering Central South UniversityChangsha 410083China

Organic depressants have low selectivity in separating molybdenite and talc because their metal sites lack activity for organics *** this study,surface modification by copper sulfate was used to induce the differential adsorption of pectin onto molybdenite and talc surfaces for enhanced flotation ***-angle experiments,scanning electron microscopy,adsorption measurements,timeof-flight secondary-ion mass spectrometry,and X-ray photoelectron spectroscopy analyses were conducted to reveal the interaction *** illustrated that molybdenite and talc could not be separated using pectin alone,while molybdenite was selectively depressed after surface modification by copper sulfate and this effect was strengthened under alkaline *** sites(Mg,Si and Mo)of talc and molybdenite themselves were unable to react with pectin,whereas Cu+would deposit and further function as active site for pectin chemisorption after surface ***,the quantity of deposited Cu sites dropped on talc surface and increased on molybdenite surface with increased pH,and the Mo atoms of molybdenite crystal were activated to take part in pectin ***,more pectin was adhered on molybdenite surface,which imparted molybdenite stronger ***,surface-modification through metal ions can enable the differential adsorption of organic depressants and enhance the flotation separation of minerals.

关键词： Molybdenite Talc Surface modification Induced adsorption

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Purification of starch and phosphorus wastewater using core-shell magnetic seeds prepared by sulfated roasting

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Journal of Environmental Sciences 2019年第7期31卷 4-16页

作者： Chunjie Du Jinsheng Yu Wei Sun Haisheng Han Yuehua Hu Pan Chen Panpan Hou runqing liu Li Wang Yue Yang Ruohua liu Lei Sun School of Minerals Processing and Bioengineering Central South University Key Laboratory of Hunan Province for Clean and Efficient Utilization of Strategic Calcium-containing Mineral Resources Central South University

Core-shell magnetic seeds with certain adsorption capacity that were prepared by sulfated roasting, served as the core of a magnetic separation technology for purification of starch wastewater. XRD and SEM results indicate that magnetite's surface transformed to be porous α-Fe_2O_3 structure. Compared with magnetite particles, the specific surface area was significantly improved to be 8.361 from 2.591 m^2/g, with little decrease in specific susceptibility. Zeta potential, FT-IR and XPS experiments indicate that both phosphate and starch adsorbed on the surface of the core-shell magnetic seeds by chemical adsorption, which fits well with the Langmuir adsorption model. The porous surface structure of magnetic seeds significantly contributes to the adsorption of phosphate and starch species, which can be efficiently removed to be 1.51 mg/L(phosphate) and 9.51 mg/L(starch) using magnetic separation.

关键词： Core-shell magnetic seeds Sulfated roasting Phosphate Starch Purification

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K型鸟粪石强化磷酸镁水泥固化Pb^(2+)

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硅酸盐学报 2023年第11期51卷 2986-2991页

作者：庞博刘润清沈阳理工大学材料科学与工程学院沈阳110159

磷酸镁水泥(MPC)可用于固化危险废物中的重金属离子,重金属离子的引入会导致固化体的长期力学性能显著降低。针对目前所存在的问题,提出了一种掺K型鸟粪石强化MPC固化Pb^(2+)的方法,在保证毒性浸出满足要求时,解决MPC固化后期力学性能... 详细信息

磷酸镁水泥(MPC)可用于固化危险废物中的重金属离子,重金属离子的引入会导致固化体的长期力学性能显著降低。针对目前所存在的问题,提出了一种掺K型鸟粪石强化MPC固化Pb^(2+)的方法,在保证毒性浸出满足要求时,解决MPC固化后期力学性能损失大的问题。结果表明:K型鸟粪石强化MPC固化Pb^(2+)的28、180 d的浸出浓度为0.63、1.91 mg/L,180 d的抗压强度与未固化Pb^(2+)的MPC(不掺K型鸟粪石)抗压强度相接近,达到了MPC满足毒性浸出要求又可以提高力学性能的强化目的;K型鸟粪石强化固化作用主要是由于提高固化体的密实度并且具有吸附性,提高了对Pb^(2+)的长期固化效果。

关键词：磷酸镁水泥固化鸟粪石铅离子

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Effect of Mineral Processing Wastewater on Electrochemistry of Galena

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Journal of Environmental Science and Engineering(A) 2012年第3期1卷 279-285页

作者： Jing Xu runqing liu Wei Sun Yuehua Hu Jingping Dai School of Resources and Environmental Engineering Wuhan University of Technology Wuhan 430070 China Henan Rock Mineral Testing Center Zhengzhou 450053 China School of Resource Processing and Bioengineering Central South University Changsha 410083 China Fankou Lead-Zinc Mine Shaoguan 512325 China

Electrochemical technology was introduced to study the floatability of galena in some wastewater samples from different processes of mineral processing plant in Fankou Lead-Zinc Mine. It is shown that the residual collector molecules in the wastewater from the thickening of lead and zinc concentrates can benefit the formation of lead xanthanate onto the surface of galena, yet, some special chemical components in the wastewater from zinc tailings and effluent may induce some surface reactions on galena, and herewith the direct reuse of this water may bring disadvantageous influence on galena flotation.

关键词： Mineral processing lead-zinc ore mineral processing wastewater surface electrochemistry.

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介绍约翰·基夫斯主编的《教育研究、方法与测量:国际手册》

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外语教学与研究 1989年第4期21卷 53-63,80页

作者：刘润清北京外国语学院

《教育研究、方法与测量:国际手册》(以下简称《教研手册》)是在Torslen Husén和Neville Postlethwaite主编的《国际教育百科全书》的基础上改编而成的。《国际教育百科全书》中最关键的两部分是教育评估与教育政策研究和方法。该书198... 详细信息

《教育研究、方法与测量:国际手册》(以下简称《教研手册》)是在Torslen Husén和Neville Postlethwaite主编的《国际教育百科全书》的基础上改编而成的。《国际教育百科全书》中最关键的两部分是教育评估与教育政策研究和方法。该书1985年问世之后,人们发现大学教师和研究生急需有关教育研究的参考书。因此有人建议,应该出版一种一卷本的手册,专门论述教育评估、政策研究、

关键词：教育研究教育评估百科全书教育政策研究国际教育大学教师研究生手册人们发现参考书

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