检索结果-南通市图书馆

High Voltage 2024年第1期9卷 56-65页

作者： Hao Hu Zhidong Jia Xilin Wang ruiyang guan Weinan Fan Simin Luo Tsinghua Shenzhen International Graduate School Tsinghua UniversityShenzhenChina guangzhou Power Supply China Southern Power Grid Company Ltd.GuangzhouChina

Silicone rubber(SR)is widely used for cable insulation and operates in multi-stress coupling *** dielectric properties and ageing performance are the essential factors affecting cable *** this study,the frequency domain spectroscopy of unaged SR and SR aged under various conditions is *** dielectric responses before and after ageing are analysed in depth by the conjoint analysis via multiple complex planes(permittivity,conductivity,and modulus).Typical conductivity and interfacial polarisation properties,as well as property changes resulting from thermal and tensile ageing,are *** results show that tensile ageing promotes conductance and interfacial polarisation,while thermal ageing shows the opposite *** on the multi-core model and charge carrier hopping transport model,thermal and tensile ageing mechanisms on the conductance and interfacial polarisation behaviours of SR are *** behaviours exhibit positively correlated changing characteristics,suggesting that the two behaviours may originate from a common *** carrier transport process,promoted by the tensile effect and slightly suppressed by the thermal effect,is the primary factor and considered an important indicator to evaluate the dielectric properties of SR insulation.

关键词： interfacial rubber insulation

Gene expression profiles at different stages of human esophageal squamous cell carcinoma

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2003年第1期9卷 9-15页

作者： JinZhou Li-QunZhao Mo-MiaoXiong Xiu-Qinwang guan-ruiyang Zong-LiangQiu MinWu Zhi-HuaLiu NationalLaboratoryofMolecularOncology CancerInstitutePekingUnionMedicalCollegeandChineseAcademyofMedicalSciencesBeijing100021China MedicalScienceInstituteofHenanProvince Zhengzhou450052China healthGeneticsCenter SchoolofPublicHealthTheUniversityofTexasHoustonHoustonTexas77225USA

AIM: To characterize the gene expression profiles in differentstages of carcinogenesis of esophageal ***: A microarray containing 588 cancer relatedgenes was employed to study the gene expression profileat different stages of esophageal squamous cell carcinomaincluding basal cell hyperplasia, high-grade dysplasia,carcinoma in situ, early and late cancer. Principle componentanalysis was performed to search the genes which wereimportant in ***: More than 100 genes were up or down regulatedin esophageal epithelial cells during the stages of basal cellhyperplasia, high-grade dysplasia, carcinoma in situ, earlyand late cancer. Principle component analysis identified aset of genes which may play important roles in the tumordevelopment. Comparison of expression profiles betweenthese stages showed that some genes, such as P160ROCK,JNK2, were activated and may play an important role inearly stages of carcinogenesis. CONCLUSION: These findings provided an esophagealcancer-specific and stage-specific expression profiles,showing that complex alterations of gene expression underliethe development of malignant phenotype of esophagealcancer cells.

关键词：食管鳞状细胞癌基因表达肿瘤生成微阵列分析 RT-PCR

考虑流层间粘力的直流接地极线路招弧角间电弧运动模型研究

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

高压电器 2021年第6期57卷 24-31,40页

作者：王涛郑连清范松海官瑞杨李昂重庆大学输配电装备及系统安全与新技术国家重点实验室重庆400044 国网四川省电力公司电力科学研究院成都610041 清华大学电机系电力系统及发电设备控制和仿真国家重点实验室北京100084 国网河南省电力公司检修公司郑州450004

直流接地极线路耐雷水平低,在遭受雷击和操作过电压时容易在绝缘子串上建立电弧,一般采取在绝缘子两端安装招弧角的方法来防止直流电弧烧蚀绝缘子。目前缺少招弧角的熄弧机理及电弧运动过程的研究,招弧角的安装均依据运行经验,缺少理论... 详细信息

直流接地极线路耐雷水平低,在遭受雷击和操作过电压时容易在绝缘子串上建立电弧,一般采取在绝缘子两端安装招弧角的方法来防止直流电弧烧蚀绝缘子。目前缺少招弧角的熄弧机理及电弧运动过程的研究,招弧角的安装均依据运行经验,缺少理论依据。文中采用链式电弧模型,考虑电流元间粘力的作用,建立了招弧角间直流电弧运动模型,提出了一种基于大矩阵存放电流元位置坐标的算法,在MATLAB中编制程序,仿真分析电弧运动过程及电弧受力,得出磁场力和热浮力为熄弧的主要动力的结论,为招弧角的安装提供理论依据。最后在小尺度直流电弧实验平台进行熄弧实验,验证了文中所建模型的有效性。

关键词：接地极线路招弧角粘力直流电弧运动模型

在线全文

学校读者我要写书评

暂无评论

可动磁柱式粗调/微调复合调感电抗器原理

重庆大学学报（自然科学版） 2018年第7期41卷 58-66页

作者：官瑞杨魏新劳王永红陈庆国哈尔滨理工大学工程电介质及其应用技术教育部重点实验室哈尔滨150080

电力电抗器电感值的快速可调和局部微调在电力系统运行过程中具有重要作用。为此,提出一种可实现粗调/微调复合调感的电抗器原理,通过调节两磁柱之间的平行间距使工作磁路及其磁阻发生改变进而实现电感值连续调节。结合磁路的欧姆定律... 详细信息

电力电抗器电感值的快速可调和局部微调在电力系统运行过程中具有重要作用。为此,提出一种可实现粗调/微调复合调感的电抗器原理,通过调节两磁柱之间的平行间距使工作磁路及其磁阻发生改变进而实现电感值连续调节。结合磁路的欧姆定律推导电感值理论计算公式;建立电抗器三维磁场仿真模型,运用有限元法计算磁场分布和电感值;详细分析电感调节特性。研究结果表明:可动磁柱的位置使工作磁路发生改变,工作磁路由一条变成3条,再由3条过渡为2条;电感值与调节距离呈双指数规律变化,随着调节距离增大,电感值减小;电感调节特性曲线分为快速调感区、过渡区和微调电感区3个区域;这种电抗器可实现粗调/微调复合调感。

关键词：电抗器可调电感可动磁柱粗调/微调

±500 kV直流换流阀用饱和电抗器温度场与电场仿真研究

在线全文

学校读者我要写书评

暂无评论

高压电器 2024年第1期60卷 128-135页

作者：毛颖科张天枫朱正一官瑞杨贾志东龚震东国网上海市电力公司上海200063 广东省复杂滨海环境电力装备可靠性工程技术研究中心清华大学深圳国际研究生院广东深圳518055

高压直流换流阀饱和电抗器在工作过程中发热量大、电场分布不均匀,使其成为阀厅的安全隐患。为改善饱和电抗器的温升效应,文中以实际±500 kV直流换流阀用饱和电抗器为研究对象,建立了改进的流体场与温度场耦合模型,该仿真模型综合考虑... 详细信息

高压直流换流阀饱和电抗器在工作过程中发热量大、电场分布不均匀,使其成为阀厅的安全隐患。为改善饱和电抗器的温升效应,文中以实际±500 kV直流换流阀用饱和电抗器为研究对象,建立了改进的流体场与温度场耦合模型,该仿真模型综合考虑流体传热、空气对流散热、绕组焦耳热和铁心涡流热损耗等实际因素,仿真计算电抗器各部件的温度场分布及其影响因素。现场验证表明该模型计算结果更接近实际工作状况。还建立静电场仿真模型,仿真计算电场畸变情况。温度场结果表明:饱和电抗器的铁心温度最高、环氧树脂次之、冷却水管路温度最低;铁心最高温度可达342 K。提高冷却水入口流速是降低饱和电抗器温度的有效方法,阀塔冷却系统的入水流速设置为1 m/s时可达最佳的冷却效果。环氧树脂、铁心和冷却水管的最高温度均与冷却水入口温度呈线性递增关系,实际工作中应使冷却水的初始温度越低越好。电场结果表明:环氧树脂与铁心交界面处出现明显的电场畸变现象,最大电场强度可达1.26×105 V/m。应在此处采取均压措施以防止电场集中而导致的局部温度过高。文中所得结论可为直流换流阀用饱和电抗器的设计提供参考。

关键词：换流阀饱和电抗器温度场电场仿真

在线全文

学校读者我要写书评

暂无评论

一种用于康复机器人手指的软体致动器设计

安徽工业大学学报（自然科学版） 2018年第4期35卷 348-351页

作者：管瑞阳王璐魏伟谢能刚安徽工业大学机械工程学院安徽马鞍山243032 马鞍山市安工大智能装备技术研究院有限公司安徽马鞍山243032 安徽工业大学管理科学与工程学院安徽马鞍山243032

针对手部运动功能障碍的患者康复问题,设计一种用于可穿戴式康复机器人手指的软体致动器。该软体致动器由具集成通道的弹性材料制成,内部为密集分布的三角形非充气腔室和菱形充气腔室,两种不同功能的腔室间隔分布,且充气腔室之间有通道... 详细信息

针对手部运动功能障碍的患者康复问题,设计一种用于可穿戴式康复机器人手指的软体致动器。该软体致动器由具集成通道的弹性材料制成,内部为密集分布的三角形非充气腔室和菱形充气腔室,两种不同功能的腔室间隔分布,且充气腔室之间有通道连接。对于该软体致动器设计,首先在ABAQUS中进行变形仿真分析,验证其可行性;然后,采用3D打印技术等制作软体致动器实物并在搭建的实验平台上进行实验。结果表明,设计的软体致动器整体结构合理,可较好地实现手指0～90°弯曲运动,弯曲角度通过气压进行调节,能够满足手指关节运动及韧带拉伸的康复训练需求。

关键词：康复机器人手指软体致动器空腔网络结构 3D打印

±500 kV直流换流阀元件高分子材料引燃特性研究

在线全文

学校读者我要写书评

暂无评论

高压电器 2022年第6期58卷 70-76页

作者：朱正一张天枫毛颖科官瑞杨贾志东龚震东吴剑敏国网上海市电力公司上海200063 广东省复杂滨海环境电力装备可靠性工程技术研究中心清华大学深圳国际研究生院广东深圳518055

在直流输电系统中晶闸管换流阀存在发生火灾的风险。文中联合热失重分析—差式扫描量热仪(TGA/DSC)以及热空气炉的实验方法,研究了换流阀主要元件的有机高分子材料在空气环境下的热失重起始温度、放热临界温度以及燃点。提出了通过TGA/... 详细信息

在直流输电系统中晶闸管换流阀存在发生火灾的风险。文中联合热失重分析—差式扫描量热仪(TGA/DSC)以及热空气炉的实验方法,研究了换流阀主要元件的有机高分子材料在空气环境下的热失重起始温度、放热临界温度以及燃点。提出了通过TGA/DSC联用实验测定换流阀高分子材料在空气环境下的燃点的方法。通过对实验确定的3项参数之间的关联性分析,确定了影响换流阀元件高分子材料的引燃温度的影响因素。研究结果表明:换流阀的引燃过程受到了高分子材料的热解过程和在高温下的放热过程的共同作用。引燃过程所需温度与热解过程发生的温度和材料在空气环境下能够依靠自身发生放热反应升温的最低温度呈正相关。文中对比研究了换流阀主要元件所包含的不同有机高分子材料在空气环境下的多项燃烧相关参数,可为换流阀元件高分子材料的引燃特性以及换流阀火灾风险评估提供借鉴。

关键词：换流阀燃点热失重高分子材料

在线全文

学校读者我要写书评

暂无评论

直流接地极线路招弧角间电弧的运动模型

四川电力技术 2019年第4期42卷 11-16页

作者：王涛郑连清范松海官瑞杨孙鹏宇输配电装备及系统安全与新技术国家重点实验室(重庆大学) 重庆400044 国网四川省电力公司电力科学研究院四川成都610041 电力系统及发电设备控制和仿真国家重点实验室(清华大学电机系) 北京100084

针对直流接地极线路在遭受雷击和操作过电压时容易在绝缘子串间建立起电弧的问题,采用链式电弧模型,考虑电流元受磁场力、热浮力和空气阻力的作用以及电流元在不同运动速度下空气阻力系数与雷诺数之间的关系,分析电流元的受力,得出电弧... 详细信息

针对直流接地极线路在遭受雷击和操作过电压时容易在绝缘子串间建立起电弧的问题,采用链式电弧模型,考虑电流元受磁场力、热浮力和空气阻力的作用以及电流元在不同运动速度下空气阻力系数与雷诺数之间的关系,分析电流元的受力,得出电弧的运动模型。通过仿真分析直流电弧在羊角型电极间的运动过程,发现直流电弧的熄弧时间与电流大小、电极张角之间存在相关关系,电弧电流和电极张角越大,直流电弧的熄弧时间越短。仿真研究结果为后续进行直流电弧试验提供理论依据。

关键词：直流电弧招弧角电弧电流电极张角运动模型

Active resilient defense control against false data injection attacks in smart grids

在线全文

学校读者我要写书评

暂无评论

Control Theory and Technology 2023年第4期21卷 515-529页

作者： Xiaoyuan Luo Lingjie Hou Xinyu Wang ruiyang Gao Shuzheng Wang Xinping guan School of Electrical Engineering Yanshan UniversityQinhuangdao066004HebeiChina School of Electrical Engineering Jiangsu Collaborative Innovation Center for Smart Distribution NetworkNanjing636600JiangsuChina School of Electronic and Electric Engineering Shanghai Jiao Tong UniversityShanghai200240China

The emerging of false data injection attacks(FDIAs)can fool the traditional detection methods by injecting false data,which has brought huge risks to the security of smart *** this reason,a resilient active defense control scheme based on interval observer detection is proposed in this paper to protect smart *** proposed active defense highlights the integration of detection and defense against FDIAs in smart ***,a dynamic physical grid model under FDIAs is modeled,in which model uncertainty and parameter uncertainty are taken into ***,an interval observer-based detection method against FDIAs is proposed,where a detection criteria using interval residual is put *** to the detection results,the resilient defense controller is triggered to defense the FDIAs if the system states are affected by *** matrix inequality(LMI)approach is applied to design the resilient controller with H_(∞)*** system with the resilient defense controller can be robust to FDIAs and the gain of the resilient controller has a certain gain *** active resilient defense approach can be built in real time and show accurate and quick respond to the injected *** effectiveness of the proposed defense scheme is verified by the simulation results on an IEEE 30-bus grid system.

关键词： Active resilient defense Attack detection Cyber attacks Cyber-attack detection Cyber grid elements Cyber threat False data injection attack Smart grids security Interval observer

Deaths and adverse events from adjuvant therapy with immune checkpoint inhibitors in solid malignant tumors:A systematic review and network meta-analysis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cancer Innovation 2022年第4期1卷 293-304页

作者： ruiyang Xie Jie Wu Bingqing Shang Xingang Bi Chuanzhen Cao Youyan guan Hongzhe Shi Jianzhong Shou Department of Urology National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina

Background:By prolonging overall survival and reducing disease recurrence rates,immune checkpoint inhibitors(ICIs)are an emerging adjuvant therapy option for patients with resectable malignant ***,the safety profile(deaths and adverse events[AEs])of adjuvant ICIs has not been fully ***:We searched the literature for phase III randomized clinical trials that compared PD-1,PD-L1,and CTLA-4 inhibitors in solid malignant *** of death,discontinuation,AEs of any cause,treatment-related adverse events(TRAEs),and immune-related adverse events(IRAEs)were extracted for the network *** meta-analyses with low incidence and poor convergence are reported as incidences with 95%confidence intervals(95%CIs).Results:Ten randomized clinical trials that included 9243 patients who received ICI adjuvant therapy were *** total,21 deaths due to TRAEs were recorded,with an overall incidence of 0.40%(95%CI:0.26–0.61).The treatment-related mortality rates for ipilimumab(0.76%,95%CI:0.31–1.55)and atezolizumab(0.56%,95%CI:0.18–1.31)were higher than for pembrolizumab(0.24%,95%CI:0.10–0.56)and nivolumab(0.30%,95%CI:0.08–0.77).The most frequent causes of death were associated with the gastrointestinal(0.10%,95%CI:0.04–0.24)and pulmonary(0.08%,95%CI:0.03–0.21)*** with the control arm,we found that nivolumab(odds ratio[OR]:2.73,95%CI:0.49–15.85)and atezolizumab(OR:12.43,95%CI:2.42–78.48)caused the fewest grade≥3 TRAEs and *** reported IRAEs of special interest were analyzed,and two agents were found to have IRAEs with incidences>10%,i.e.,hepatitis for atezolizumab(14.80%,95%CI:12.53–17.32)and hypophysitis for ipilimumab(13.53%,95%CI:11.38–15.90).Conclusions:Ipilimumab and atezolizumab were correlated with higher treatment-related death rates than pembrolizumab and nivolumab,in which the gastrointestinal and pulmonary systems were mostly *** severe TRAEs and IRAEs,nivolumab and atezolizumab are lik

关键词： immune checkpoint inhibitor adjuvant therapy cancer adverse event death