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Does topical vancomycin prevent fracture-related infections in closed fractures undergoing open reduction and internal fixation?A randomised controlled trial

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Chinese Journal of Traumatology 2024年第2期27卷 71-76页

作者： Mohit Gandhi Gopisankar Balaji Jagdish Menon ruben raj thomas Department of Orthopaedics Jawaharlal Institute of Postgraduate Medical Education and ResearchPondicherryIndia Department of Preventive and Social Medicine Jawaharlal Institute of Postgraduate Medical Education and ResearchPondicherryIndia

Purpose:The role of topical vancomycin in fracture-related infection(FRI)is *** few studies have reported their efficacy in open and high-risk extremity *** study aimed to assess topical vancomycin's role in reducing FRI in closed fractures undergoing open surgical intervention with an ***:This prospective randomized cohort study was carried out between February 2021 to January *** with isolated closed fractures,who were planned for open reduction and internal fixation within 2 weeks from the time of injury were included for this *** data collected included age,gender,socioeconomic status,mechanism of injury,diagnosis,Tscherne classification,and time interval to take up for *** were randomized into the intervention and control groups using the block randomization *** control group received only systemic antibiotic prophylaxis,whereas the intervention group received topical application of vancomycin powder in the surgical wound alongside systemic antibiotic *** primary outcome measure was the incidence of FRI among these *** and radiological findings and culture reports(in cases with infection)were recorded during the post-operative period and at 6 weeks of *** relevant statistical calculations were done using STATA statistical/data analysis-parallel edition version 16.0(StataCorp LLC).The quantitative variables like age and duration of the surgery were assessed for normalcy by Shapiro-Wilk W *** independent samples t-test with equal variances was applied to the age ***'s exact test was used for the analysis of the primary outcome measure(presence of FRI following surgery),and"Risk of FRI"and"Risk difference"between the 2 groups was *** strength of the association between qualitative variables was assessed using the Fisher's exact and Chi-square tests,***:There were 88 patients included in this *** statistical si

关键词： Infections Antibiotics Vancomycin Fractures

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Improved DHOA-Fuzzy Based Load Scheduling in IoT Cloud Environment

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Computers, Materials & Continua 2022年第5期71卷 4101-4114页

作者： R.Joshua Samuel raj V.Ilango Prince thomas V.R.Uma Fahd N.Al-Wesabi Radwa Marzouk Anwer Mustafa Hilal Department of Information Science&Engineering CMR Institute of TechnologyBengaluru560037India Department of Computer Application CMR Institute of TechnologyBangalore560037India School of Computing Woldia Institute of TechnologyWoldia UniversityEthiopia Department of Commerce School of CommerceFinance and AccountancyChrist UniversityBangalore560029India Department of Computer Science College of Science&Art at MahayilKing Khalid UniversitySaudi Arabia Faculty of Computer and IT Sana’a UniversityYemen Department of Information Systems College of Computer and Information SciencesPrincess Nourah Bint Abdulrahman UniversitySaudi Arabia Department of Computer and Self Development Preparatory Year DeanshipPrince Sattam bin Abdulaziz UniversityAlkharjSaudi Arabia

Internet of things (IoT) has been significantly raised owing to thedevelopment of broadband access network, machine learning (ML), big dataanalytics (BDA), cloud computing (CC), and so on. The development of IoTtechnologies has resulted in a massive quantity of data due to the existenceof several people linking through distinct physical components, indicatingthe status of the CC environment. In the IoT, load scheduling is realistictechnique in distinct data center to guarantee the network suitability by fallingthe computer hardware and software catastrophe and with right utilize ofresource. The ideal load balancer improves many factors of Quality of Service(QoS) like resource performance, scalability, response time, error tolerance,and efficiency. The scholar is assumed as load scheduling a vital problem inIoT environment. There are many techniques accessible to load scheduling inIoT environments. With this motivation, this paper presents an improved deerhunting optimization algorithm with Type II fuzzy logic (IDHOA-T2F) modelfor load scheduling in IoT environment. The goal of the IDHOA-T2F is todiminish the energy utilization of integrated circuit of IoT node and enhancethe load scheduling in IoT environments. The IDHOA technique is derivedby integrating the concepts of Nelder Mead (NM) with the DHOA. Theproposed model also synthesized the T2L based on fuzzy logic (FL) systemsto counterbalance the load distribution. The proposed model finds usefulto improve the efficiency of IoT system. For validating the enhanced loadscheduling performance of the IDHOA-T2F technique, a series of simulationstake place to highlight the improved performance. The experimental outcomesdemonstrate the capable outcome of the IDHOA-T2F technique over therecent techniques.

关键词： Load scheduling internet of things cloud computing metaheuristics fuzzy logic

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Geomechanical response of overburden caused by CO_2 injection into a depleted oil reservoir

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Journal of Rock Mechanics and Geotechnical Engineering 2016年第6期8卷 860-872页

作者： Hema J.Siriwardane raj K.Gondle Sai B.Varre Grant S.Bromhal thomas H.Wilson Department of Civil and Environmental Engineering West Virginia University Department of Civil and Environmental Engineering University of Massachusetts Lowell National Energy Technology Laboratory U.S. Department of Energy Department of Geology and Geography West Virginia University

This study investigates the hydro-mechanical aspects of carbon dioxide(CO2) injection into a depleted oil reservoir through the use of coupled multiphase fluid flow and geomechanical *** singlephase and multiphase fluid flow analyses coupled with geomechanics were carried out at the West Pearl Queen depleted oil reservoir site,and modeling results were compared with available measured *** site geology and the material properties determined on the basis of available geophysical data were used in the *** results from the coupled multiphase fluid flow and geomechanical analyses show that computed fluid pressures match well with available measured *** hydromechanical properties of the reservoir have a significant influence on computed fluid pressures and surface ***,an accurate geologic characterization of the sequestration site and determination of engineering properties are important issues for the reliability of model *** computed fluid pressure response is also significantly influenced by the relative permeability curves used in multiphase fluid flow *** the multiphase fluid flow models provide more accurate fluid pressure response,single-phase fluid flow models can be used to obtain approximate *** ground surface deformations obtained from single-phase fluid flow models coupled with geomechanics are slightly lower than those predicted by multiphase fluid flow models coupled with ***,the advantage of a single-phase model is the *** field monitoring of subsurface fluid pressure and ground surface deformations during fluid injection can be used in calibrating coupled fluid flow and geomechanical *** calibrated models can be used for investigating the performance of large-scale CO2storage in depleted oil reservoirs.

关键词： Depleted oil reservoirs Multiphase flow Geomechanics Geologic sequestration Computational modeling

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High-performance multilayer WSe2 field-effect transistors with carrier type control

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Nano Research 2018年第2期11卷 722-730页

作者： Pudasaini, Pushpa raj Oyedele, Akinola Zhang, Cheng Stanford, Michael G. Cross, Nicholas Wong, Anthony T. Hoffman, Anna N. Xiao, Kai Duscher, Gerd Mandrus, David G. Ward, thomas Z. Rack, Philip D. Department of Materials Science and Engineering University of Tennessee Knoxville USA Center for Nanophase Materials Sciences Oak Ridge National Laboratory Oak Ridge USA Bredesen Center for Interdisciplinary Research and Graduate Education University of Tennessee Knoxville USA Materials Science and Technology Division Oak Ridge National Laboratory Oak Ridge USA

In this stud high-performance multilayer WSe2 field-effect transistor （FET） devices with carrier type control are demonstrated via thickness modulation and a remote oxygen plasma surface treatment. Carrier type control in multilayer WSe2 FET devices with Cr/Au contacts is initially demonstrated by modulating the WSe2 thickness. The carrier type evolves with increasing WSe2 channel thickness, being p-type, ambipolar, and n-type at thicknesses 〈 3, - 4, and 〉 5 nm, respectively. The thickness-dependent carrier type is attributed to changes in the bandgap of WSe2 as a function of the thickness and the carrier band offsets relative to the metal contacts. Furthermore, we present a strong hole carrier doping effect via remote oxygen plasma treatment. It non-degenerately converts n-type characteristics into p-type and enhances field-effect hole mobility by three orders of magnitude. This work demonstrates progress towards the realization of high-performance multilayer WSe2 FETs with carrier type control, potentially extendable to other transition metal dichalcogenides, for future electronic and oDtoelectronic alpplications.

关键词： transition metaldichalcogenide field-effect transistors carrier control plasma treatment carrier mobility

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无穷无尽的几何空间

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缤纷 2004年第6期 51-59页

作者： ruben Anderegg 姚京 thomas Hammerli

这是一次纯粹的心灵创作.那些蕴育在无穷无尽空间中的思想.通过建筑向外延伸实现着精神上的伸扬.这是一座位于伯尔尼Oberland的私人别墅,鸟瞰整个建筑,仿佛是漂浮在绿坪上的汉白玉方盒。

关键词：几何空间立方体建筑师住宅建筑空间占有率内部空间创作房屋漂浮起居室

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Geomorphologic and Hydrogeologic Characteristics of Populated Rockslide Deposits (Sagarmatha National Park, Khumbu Himal, Nepal)

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Journal of Water Resource and Protection 2015年第13期7卷 1038-1048页

作者： Joachim Gö tz Johannes thomas Weidinger Stefan Kraxberger Anne-Lise Hennecke Johannes Buckel Basanta raj Adhikari Department of Geography and Geology University of Salzburg Salzburg Austria Erkudok-Institute K-Hof-Museums of Gmunden Gmunden Austria Department of Civil Engineering Tribhuvan University Kathmandu Nepal

Surface morphology and internal composition of large rockslide deposits have been frequently studied, but their hydrogeologic conditions and consequences for (drinking) water quality and quantity on such deposits are largely unknown. In this study we provide first information on this critical relationship for two large rockslide deposits in the Khumbu Himal (Nepal), which are at the same time the main settlement areas in the region. In the first step, we investigated the Lukla and the Namche-Khumjung rockslides with respect to their dimensions and internal composition based on orthophotos and digital elevation models, geomorphologic field mapping, and the analysis of rockslide outcrops. Secondly, we studied their hydrogeologic characteristics by means of spring water mapping, sampling and analyses. As a consequence of the fragmented and highly shattered rockslide material, both deposits are characterized by 1) effective infiltration, 2) short residence times of percolating water and 3) by only small amounts of available spring water and surface runoff at all. Human activity on the studied rockslide deposits can therefore be described as an ambivalent relationship: On the one hand, the rockslide deposits provide a gentle topography and the only available areas for extensive settlements and agriculture in the steep upper DudhKosi catchment;On the other hand, their internal composition accounts for water scarcity—a critical issue for the local population demanding for adaptation strategies, especially in the light of the ever—increasing trekking and expedition tourism in the region.

关键词： Khumbu Himal Geomorphologic and Hydrogeologic Mapping Rockslide Morphology Rockslide Hydrology Water Scarcity

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Extreme multiexciton emission from deterministically assembled single-emitter subwavelength plasmonic patch antennas

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Light(Science & Applications) 2020年第1期9卷 1697-1705页

作者： Amit raj Dhawan Cherif Belacel Juan Uriel Esparza-Villa Michel Nasilowski Zhiming Wang Catherine Schwob Jean-Paul Hugonin Laurent Coolen Benoit Dubertret Pascale Senellart Agnes Maitre Institute of Fundamental and Frontier Sciences University of Electronic Science and Technology of ChinaChengdu 610054People’s Republic of China Sorbonne Universite CNRSInstitut des Nanosciences de ParisUMR 758875005 ParisFrance Centre de Nanosciences et de Nanotechnologies et de Nanostructures CNRS UMR9001Universite Paris-Saclay10 boulevard Thomas Gobert91120 MarcoussisFrance Laboratoire de Physique et d’Etude des Materiaux ESPCI-ParisTechPSL Research UniversitySorbonne UniversiteCNRS UMR 821310 rue VauquelinParis 75005France Laboratoire Charles Fabry Institut d’Optique Graduate SchoolCNRS UMR 8501Universite Paris Saclay2 avenue Augustin Fresnel91127 Palaiseau CedexFrance

Coupling nano-emitters to plasmonic antennas is a key milestone for the development of nanoscale quantum light *** challenge,however,is the precise nanoscale positioning of the emitter in the ***,we present a laser etching protocol that deterministically positions a single colloidal CdSe/CdS core/shell quantum dot emitter inside a subwavelength plasmonic patch antenna with three-dimensional nanoscale *** exploiting the properties of metal–insulator–metal structures at the nanoscale,the fabricated single-emitter antenna exhibits a very high-Purcell factor(>72)and a brightness enhancement of a factor of *** to the unprecedented quenching of Auger processes and the strong acceleration of the multiexciton emission,more than 4 photons per pulse can be emitted by a single quantum dot,thus increasing the device *** technology can be applied to a wide range of photonic nanostructures and emitters,paving the way for scalable and reliable fabrication of ultracompact light sources.

关键词： patch precise acceleration

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百花凋零

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商业周刊（中文版） 2020年第11期 68-73页

作者： Zeke Faux David Herbling ruben Munsterman Sem Langendijk(摄影) Brian Otieno(摄影) Bryan thomas(摄影) 汪泽(译) 不详

规模达85亿美元的全球鲜切花贸易遭受重创,体现出新冠疫情对供应链的破坏速度之快、程度之深,即使在疫情尚不严重的地方也是如此。仅仅几周的隔离之后,美国佛蒙特州的奶农就因为学校取消订单而将牛奶倒进了化粪池。欧洲边境关闭导致外... 详细信息

规模达85亿美元的全球鲜切花贸易遭受重创,体现出新冠疫情对供应链的破坏速度之快、程度之深,即使在疫情尚不严重的地方也是如此。仅仅几周的隔离之后,美国佛蒙特州的奶农就因为学校取消订单而将牛奶倒进了化粪池。欧洲边境关闭导致外来的农场工人无法入境,只得任由农作物在田间枯萎。

关键词：供应链破坏速度佛蒙特州百花凋零鲜切花化粪池农作物疫情

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Biodegradable polymer stents vs second generation drug eluting stents:A meta-analysis and systematic review of randomized controlled trials

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World Journal of Cardiology 2016年第2期8卷 240-246页

作者： Bhavi Pandya Sainath Gaddam Muhammad Raza Deepak Asti Nikhil Nalluri thomas Vazzana ruben Kandov James Lafferty Department of Internal Medicine Staten Island University Hospital Department of Cardiology Staten Island University Hospital

AIM: To evaluate the premise, that biodegradable polymer drug eluting stents(BD-DES) could improve clinical outcomes compared to second generation permanent polymer drug eluting stents(PP-DES), we pooled the data from all the available randomized control trials(RCT) comparing the clinical performance of both these ***: A systematic literature search of Pub Med, Cochrane, Google scholar databases, EMBASE, MEDLINE and SCOPUS was performed during time period of January 2001 to April 2015 for RCT and comparing safety and efficacy of BD-DES vs second generation PP-DES. The primary outcomes of interest were definite stent thrombosis, target lesion revascularization, myocardial infarction, cardiac deaths and total deaths during the study period. RESULTS: A total of 11 RCT's with a total of 12644 patients were included in the meta-analysis, with 6598 patients in BD-DES vs 6046 patients in second generation PP-DES. The mean follow up period was 16 mo. Pooled analysis showed non-inferiority of BD-DES, comparing events of stent thrombosis(OR = 1.42, 95%CI: 0.79-2.52, P = 0.24), target lesion revascularization(OR = 0.99, 95%CI: 0.84-1.17, P = 0.92), myocardial infarction(OR = 1.06, 95%CI: 0.86-1.29, P = 0.92), cardiac deaths(OR = 1.07, 95%CI 0.82-1.41, P = 0.94) and total deaths(OR = 0.96, 95%CI: 0.80-1.17, P = 0.71).CONCLUSION: BD-DES, when compared to second generation PP-DES, showed no significant advantage and the outcomes were comparable between both the groups.

关键词： Stent design Drug eluting stent Zotarolimus eluting stent Cobalt-chromium stent Biodegradable drug eluting stent

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Papillary fibroelastoma of the aortic valve:An unusual cause of angina

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World Journal of Cardiology 2013年第4期5卷 102-105页

作者： Madan raj Aryal Madan Badal Naba raj Mainali Leena Jalota rajesh Pradhan Department of Medicine Reading Health SystemWest ReadingPA 19611United States Department of Medicine Division of CardiologyThomas Jefferson University HospitalPhiladelphiaPA 19107United States

Papillary fibroelastoma of the aortic valve is an uncommon benign tumor of the heart that can present with embolic *** report a case of 54-year-old lady with exertional chest pain and prior history of ST segment elevation myocardial infarction who was subsequently found to have a fibroelastoma of the aortic *** absence of angiographically significant coronary artery disease and resolution of anginal symptoms post-surgery in our patient points to the possibility of fibroelastoma causing these anginal *** uncommon,fibroelastoma are being recognized more frequently with the help of transesophageal ***,in the absence of significant coronary artery disease,we emphasize the importance of consideration of papillary fibroelastoma of the aortic valve as a cause of *** also discuss the key aspects of the fibroelastoma including presentation,diagnostic modalities and treatment options.

关键词： Papillary fibroelastoma Angina Aortic valve Surgical resection Embolic event

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