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Phenolic profile， antioxidant properties， and beneficial gut microbiota associated with freeze dried Lycium ruthenicum

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Food Science and Human Wellness 2024年

作者： Jing Huang Xueni Fan Xin Li Dingmei Dai Wenjie Huang dong ruan Shijuan Yan Xiaodan Huang School of Public Health， Lanzhou University Guangdong Key Laboratory for Crop Germplasm Resources Preservation and Utilization， Agro-biological Gene Research Center， Guangdong Academy of Agricultural Sciences Institute of Animal Science， Guangdong Academy of Agricultural Sciences， Key Laboratory of Animal Nutrition and Feed Science in South China， Ministry of Agriculture and Rural Affairs， State Key Laboratory of Livestock and Poultry Breeding， Guangdong Key Laboratory of Animal Breeding and Nutrition

Black wolfberry (Lycium ruthenicum) is enriched in phytochemical metabolites which can benefit human health. However， few studies have examined the effects of different fruit drying methods on its polyphenol content， antioxidant activity， and anti-inflammatory activity. In addition， whether and how consuming dried black wolfberry affects gut microbiota has not been reported. Here， we assessed the phytochemical profile and bioactivities of black wolfberry dried through different methods， and subsequently characterized changes in human fecal microbiota associated with freeze-dried black wolfberry in vitro. The results showed that freeze-dried samples retained higher total polyphenols (49.68 ± 1.62) mg GAE/g， tannins (38.64 ± 1.35) mg GAE/g， and proanthocyanidins (3.35 ± 0.30) mg/g compared to sun drying or hot air drying (P < 0.05)， and exhibited higher antioxidant and anti-inflammatory activities. In bioreactor fermentations of human fecal inoculum， freeze-dried black wolfberry was associated with increased species richness and alpha diversity. At the genus level， fermentations treated with black wolfberry had higher abundance of Lactic Acid Bacteria including Lactococcus， Bifidobacterium， Lactobacillus， Pediococcus and Weissella， as well as butyrate-producing bacteria compared to the untreated samples， suggesting enrichment for taxa associated with a healthy gut microbiome. In addition， the black wolfberry treatment group had higher levels of short-chain fatty acids， which was consistent with PICRUSt2 inference. This study defines an optimal method for black wolfberry preservation to retain the beneficial compounds， and provides a foundation for further exploration of its potential benefits for human gut microbiota.

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姜黄素吸收代谢及其对家禽繁殖调控作用研究进展

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广东农业科学 2024年第3期51卷 136-147页

作者：王君雁阮栋蒋守群广东海洋大学滨海农业学院广东湛江524088 广东省农业科学院动物科学研究所/猪禽种业全国重点实验室/农业农村部华南动物营养与饲料重点实验室/广东省畜禽育种与营养研究重点实验室广东广州510640

姜黄素是从姜科植物(如姜黄)、天南星科植物根茎中提取出来的多酚类化合物,主要在动物肠道中进行吸收代谢,具有抗炎、抗氧化、抗凋亡、抗衰老、神经保护、免疫调节及代谢调控等作用。姜黄素在动物体内生物利用度差,为提高姜黄素的利用度... 详细信息

姜黄素是从姜科植物(如姜黄)、天南星科植物根茎中提取出来的多酚类化合物,主要在动物肠道中进行吸收代谢,具有抗炎、抗氧化、抗凋亡、抗衰老、神经保护、免疫调节及代谢调控等作用。姜黄素在动物体内生物利用度差,为提高姜黄素的利用度,通常将其制成多种制剂及配型(如膜制剂、纤维制剂、乳制剂、水凝胶制剂、胡椒碱、半萜类化合物、环糊精、葫芦巴膳食纤维和卵磷脂)。不同的制剂及配型可增加姜黄素产物稳定性,保障姜黄素的有效利用。家禽主要通过下丘脑-性腺轴负反馈调节机制来调控生殖细胞发育,实现繁殖调控。此外,家禽的繁殖性能易受外部因素影响,其中光照的影响最大。光照刺激产生的褪黑素具有强抗氧化性,能通过缓解卵巢和睾丸组织的线粒体功能障碍来抑制凋亡和衰老,保障下丘脑-性腺轴负反馈调节机制的稳定和氧化应激状态下的卵泡发育。肠道微生物产生的血清素是褪黑素的前体物质,可以影响褪黑素的生成;其次肠道微生物刺激肠上皮细胞中的传入神经直接影响下丘脑分泌促性腺激素释放激素;最后,肠道内产生的雌二醇(E2)可以通过血液进入卵巢组织,并促进卵巢发育。研究发现,姜黄素可通过肠道微生物产生的短链脂肪酸在体内发挥功能作用,但姜黄素是否通过肠道微生物产生的短链脂肪酸来影响家禽的繁殖性能亟待探究。该文综述了姜黄素的生物活性、代谢方式、产品研发利用以及对家禽繁殖调控的作用机制及相关研究进展,旨在为姜黄素作为饲料添加剂在家禽生产中的合理应用提供理论参考。

关键词：姜黄素家禽吸收代谢繁殖调控肠道微生物

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N = 4 Supersymmetric Morse Oscillator and Its Spectrum-Generating Algebra

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Communications in Theoretical Physics 2005年第3X期44卷 499-504页

作者： ruan dong Department of Physics Tsinghua University Beijing 100084 China Center of Theoretical Nuclear Physics National Laboratory of Heavy Ion Accelerator Lanzhou 730000 China Key Laboratory of Quantum Information and Measurements of Ministry of Education Tsinghua University Beijing 100084 China Institute of Theoretical Physics Academia Sinica Beijing 100080 China

In this paper N = 4 supersymmetry of generalized Morse oscillators in one dimension is studied. Both bound states and scattering states of its four superpartner Hamiltonians are analyzed by using unitary irreducible representations of the noncompact Lie algebra su(1,1). The spectrum-generating algebra governing the Hamiltonian of the N = 4 supersymmetric Morse oscillator is shown to be connected with the realization of Lie superalgebra osp(1,2)or B(0,1) in terms of the variables of a supersymmetric two-dimensional harmonic oscillator.

关键词： generalized Morse oscillator supersymmetric quantum mechanics su(1 1) osp(1 2)

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冲击荷载作用下Levy型索穹顶结构动力响应分析

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建筑钢结构进展 2024年第8期26卷 51-59页

作者：高占远朱佳静薛素铎阮冬天津城建大学天津市土木建筑结构防护与加固重点实验室天津300384 北京工业大学空间结构研究中心北京100124 斯威本科技大学科学、工程与技术学院澳大利亚墨尔本Vic 3122

建立Levy型索穹顶结构有限元分析模型,给出有限元结果合理性的判定准则,提出冲击失效准则。进行大量冲击工况下的动力响应全过程分析,给出杆件破坏分布规律和失效模式,揭示结构在竖向冲击荷载作用下的失效机理。依据冲击失效机理及参数... 详细信息

建立Levy型索穹顶结构有限元分析模型,给出有限元结果合理性的判定准则,提出冲击失效准则。进行大量冲击工况下的动力响应全过程分析,给出杆件破坏分布规律和失效模式,揭示结构在竖向冲击荷载作用下的失效机理。依据冲击失效机理及参数分析,提出抗冲击措施。研究结果表明:所有冲击工况均符合冲击判定准则,在所选竖向冲击荷载范围内,Levy型索穹顶结构的失效模式可分为4种,即结构轻度损伤、结构局部1级失效、结构局部2级失效和结构整体破坏。随着冲击动能的增加,结构的动力响应模式逐渐呈模式1→模式2→模式3→模式4的发展趋势。通过分析可知,结构的动力响应模式由结构的能量吸收值及构件两端速度差决定。

关键词：索穹顶结构冲击荷载动力响应失效模式失效机理

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大功率磁悬浮泵宽流道叶轮的水力性能分析

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液压与气动 2024年第3期48卷 91-98页

作者：白晓蓉胡亮阮晓东苏芮傅新浙江大学流体动力与机电系统国家重点实验室浙江杭州310027

磁悬浮泵将磁悬浮电机与泵体结构一体化,利用磁场驱动叶轮旋转,并对其余5个自由度进行主/被动悬浮约束,从而实现完全无轴承的介质泵送,被广泛用于半导体制造等领域的电子化学品超洁净输送。目前,大功率磁悬浮泵产品存在泵送效率低的问题... 详细信息

磁悬浮泵将磁悬浮电机与泵体结构一体化,利用磁场驱动叶轮旋转,并对其余5个自由度进行主/被动悬浮约束,从而实现完全无轴承的介质泵送,被广泛用于半导体制造等领域的电子化学品超洁净输送。目前,大功率磁悬浮泵产品存在泵送效率低的问题,同时随着功率的增加,磁悬浮泵的液压轴向力平衡问题越发突出。为此,设计了一种大功率磁悬浮泵的宽流道叶轮,并对其进行水力效率、液压轴向力及液压径向力分析。通过仿真研究,首先阐述了窄流道效应对大功率磁悬浮泵水力效率的影响,并对宽流道叶轮及窄流道叶轮进行水力效率对比分析;其次对宽流道叶轮的液压轴向力及径向力进行计算分析,表明宽流道设计对叶轮液压轴向力及径向力的影响,为大功率磁悬浮泵高效水力设计开发提供关键技术支撑。

关键词：磁悬浮泵宽流道水力效率轴向力径向力

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Analysis of effect of nicotine on microbial community structure in sediment using PCR-DGGE fingerprinting

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Water Science and Engineering 2015年第4期8卷 309-314页

作者： Ai-dong ruan Chen-xiao Liu State Key Laboratory of Hydrology-Water Resources and Hydraulic Engineering Hohai University

Solid or liquid waste containing a high concentration of nicotine can pollute sediment in rivers and lakes, and may destroy the ecological balance if it is directly discharged into the environment without any treatment. In this study, the polymerase chain reaction （PCR） and denaturing gradient gel electrophoresis （DGGE） method was used to analyze the variation of the microbial community structure in the control and nicotinecontaminated sediment samples with nicotine concentration and time of exposure. The results demonstrated that the growth of some bacterial species in the nicotine-contaminated sediment samples was inhibited during the exposure. Some bacteria decreased in species diversity and in quantity with the increase of nicotine concentration or time of exposure, while other bacteria were enriched under the effect of nicotine, and their DGGE bands changed from undertones to deep colors. The microbial community structure, however, showed a wide variation in the nicotine- contaminated sediment samples, especially in the sediment samples treated with high-concentration nicotine. The Jaccard index was only 35.1% between the initial sediment sample and the sediment sample with a nicotine concentration of 0.030 μg/g after 28 d of exposure. Diversity indices showed that the contaminated groups had a similar trend over time. The diversity indices of contaminated groups all decreased in the first 7 d after exposure, then increased until day 42. It has been found that nicotine decreased the diversity of the microbial community in the sediment.

关键词： Nicotine Sediment PCR-DGGE Microbial community structure Diversity index

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A Maple Package on Symbolic Computation of Hirota Bilinear Form for Nonlinear Equations

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Communications in Theoretical Physics 2009年第11期52卷 801-807页

作者： YANG Xu-dong ruan Hang-Yu Department of Physics Ningbo University Ningbo 315211 China

An improved algorithm for symbolic computation of Hirota bilinear forms of KdV-type equations withlogarithmic transformations is *** the algorithm,the general assumption of Hirota bilinear form is successfullyreduced based on the property of uniformity in ***,we discard the integral operation in the *** software package HBFTrans is written in Maple and its running effectiveness is tested by a variety solitonequations.

关键词： Hirota bilinear form nonlinear equation, symbolic algebra

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Single boson realizations of the deformed angular momentum algebra of Witten's types

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Chinese Science Bulletin 2013年第18期58卷 2039-2043页

作者： HUANG HuaJun ruan dong Department of Physics Tsinghua University

By generalizing the Holstein-Primakoff realization and the Dyson realization of the Lie algebra SU(2),various realizations of the deformed angular momentum algebra Rc0,c1,c2q,s,a five-parameter deformed SU(2) by combining Witten's two deformation schemes,are investigated in terms of the single boson and the single inversion boson *** each kind,the unitary realization,the non-unitary realization,and their connection by the corresponding similarity transformation are respectively discussed.

关键词：李超代数玻色子变形类型角动量 SU(2) 相似变换荷斯坦

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Additively manufactured fiber-reinforced composites:A review of mechanical behavior and opportunities

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Journal of Materials Science & Technology 2022年第24期119卷 219-244页

作者： Jiahui Li Yvonne Durandet Xiaodong Huang Guangyong Sun dong ruan Department of Mechanical Engineering and Product Design Engineering School of EngineeringSwinburne University of TechnologyHawthornVIC 3122Australia State Key Laboratory of Advanced Design and Manufacture for Vehicle Body Hunan UniversityChangsha 410082China

Recent developments in additive manufacturing techniques have facilitated the fabrication of fiberreinforced composite *** this paper,the mechanical properties and deformation mechanisms of discontinuous and continuous fiber-reinforced composites fabricated by various additive manufacturing techniques are comprehensively *** effects of fiber type,orientation and weight/volume fraction,printing path,and stacking sequence on the mechanical properties of additively manufactured composites are *** addition,the applications of additively manufactured composites,the main challenges of the current additive manufacturing techniques,and recommendations for future work are also presented.

关键词： Additive manufacturing Discontinuous and continuous fiber-reinforced composites Mechanical properties Deformation mechanism Applications

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N ＝ 4 Superconformal Quantum Mechanics in One Dimension and Its Algebraic Structure

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Communications in Theoretical Physics 2002年第7期38卷 11-14页

作者： ruan dong GUO Hao SUN Hong-Zhou Department of Physics Tsinghua University Beijing 100084 China The Key Laboratory of Quantum Information and Measurements of Ministry of Education Tsinghua University Beijing 100084 China Center of Theoretical Nuclear Physics National Laboratory of Department of Physics Tsinghua University Beijing 100084 China Department of Physics Tsinghua University Beijing 100084 China Center of Theoretical Nuclear Physics National Laboratory of Heavy Ion Accelerator Lanzhou 730000 China Institute of Theoretical Physics Academia Sinica Beijing 100080 China

N = 4 superconformal quantum mechanics of nonrelativistic particles in the typical 1/x2-potentials, which holds not only supersymmetry but also dynamical conformal symmetry, is studied. The corresponding superconformal quantum mechanical algebra, which contains supersymmetric quantum mechanical algebra with four supercharges and conformal algebra as subalgebras, and its two canonical group chains are established.

关键词： supersymmetry, conformal symmetry, superconformal algebra

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