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EXPERIMENTAL STUDY OF AIRFLOW INDUCED BY PUMPING TESTS IN UNCONFINED AQUIFER WITH LOW-PERMEABILITY CAP

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Journal of Hydrodynamics 2012年第4期24卷 605-608页

作者： HUANG Hui QIAN jia-zhong KUANG Xing-xing CHEN Zhou LI ru-zhong School of Resources and Environmental Engineering Hefei University of Technology Hefei 230009 China Department of Earth Sciences The University of Hong Kong Hong Kong China

The airflow in unsaturated soils is an issue of great importance in various fields such as in agricultural, nuclear, environmental engineering. However, up to now, little attention was paid to the generation of the airflow induced by a pumping test in an unconfined aquifer with a low-permeability cap and its influence on the pumping test. In this paper, pumping tests were carried out experimentally in the aquifer with a low-permeability cap in order to study the influence of the airflow induced by the pumping on the drawdown of the tests. It is shown that：（1） there is an airflow with negative pressure generated by the pumping tests, （2） the Negative air Pressure （NP） is increased with the pumping rate but decreased with the radial distance, and （3） the NP also changes with the initial water table. The results provide a good basis for further theoretical study of the airflow induced by pumping.

关键词： low-permeability cap pumping tests airflow unconfined aquifer drawdown

The Pathway of China’s Integrated Delivery System:Based on the Analysis of the Medical Consortium Policies

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Current Medical Science 2022年第6期42卷 1164-1171页

作者： Huan GAO Xing-li DU jia-zhi liao Li XIANG School of Medicine and Health Management Huazhong University of Science and TechnologyWuhan430030China Tongji Hospital Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan430030China

With the deepening of China’s health-care reform,an integrated delivery system has gradually emerged with the function of improving the efficiency of the health-care delivery *** China’s integrated delivery system,a medical consortium plays an important role in integrating public hospitals and primary care *** first medical consortium policy issued after the COVID-19 pandemic apparently placed hope on accelerating the implementation of a medical consortium and tiered health-care delivery *** paper illustrates the possible future pathway of China’s medical consortium through retrospection of the 10-year process,changes of the series of policies,and characteristics of the policy issued in *** considered that a fully integrated medical consortium would be a major phenomenon in China's medical industry,which would lead to the formation of a dualistic care pattern in China.

关键词： health-care reform integrated delivery system medical consortium tiered health-care delivery system health policy

Intelligent Covert Communication Design for Cooperative Cognitive Radio Network

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China Communications 2023年第7期20卷 122-136页

作者： Zan Li jia Shi Chao Wang Danyang Wang Xiaomeng Li Xiaomin liao The National Key Laboratory of Space-Air-Ground Integrated Service Network Xidian UniversityXi’an 710071China School of Information and Communications National University of Defense TechnologyWuhan 430035China

Extensive research attentions have been devoted to studying cooperative cognitive radio networks(CCRNs),where secondary users(SU)providing cooperative transmissions can be permitted by primary users(PU)to use *** order to maximize SU’s utility,SU may transmit its own information during the period of cooperative transmission,which stimulates the use of covert transmission against PU’s *** this sake,this article reviews the motivations of studying covert communications in *** particular,three intelligent covert transmission approaches are developed for maximizing SU’s utility in CCRNs,namely,intelligent parasitic covert transmission(IPCT),intelligent jammer aided covert transmission(IJCT)and intelligent reflecting surface assisted covert transmission(IRSC).Further,some raw performance evaluations are discussed,and a range of potential research directions are also provided.

关键词： cognitive radio networks covert transmis-sion machine learning

Intuitionistic Fuzzy Laplacian Twin Support Vector Machine for Semi-supervised Classification

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Journal of the Operations Research Society of China 2022年第1期10卷 89-112页

作者： jia-Bin Zhou Yan-Qin Bai Yan-ru Guo Hai-Xiang Lin Department of Mathematics Shanghai UniversityShanghai 200444China Delft Institute of Applied Mathematics Delft University of TechnologyDelft 2600GAThe Netherlands

In general,data contain noises which come from faulty instruments,flawed measurements or faulty *** with data in the context of classification or regression is inevitably affected by noises in the *** order to remove or greatly reduce the impact of noises,we introduce the ideas of fuzzy membership functions and the Laplacian twin support vector machine(Lap-TSVM).A formulation of the linear intuitionistic fuzzy Laplacian twin support vector machine(IFLap-TSVM)is ***,we extend the linear IFLap-TSVM to the nonlinear case by kernel *** proposed IFLap-TSVM resolves the negative impact of noises and outliers by using fuzzy membership functions and is a more accurate reasonable classi-fier by using the geometric distribution information of labeled data and unlabeled data based on manifold *** with constructed artificial datasets,several UCI benchmark datasets and MNIST dataset show that the IFLap-TSVM has better classification accuracy than other state-of-the-art twin support vector machine(TSVM),intuitionistic fuzzy twin support vector machine(IFTSVM)and Lap-TSVM.

关键词： Twin support vector machine Semi-supervised classification Intuitionistic fuzzy Manifold regularization Noisy data

Novel insights into histone lysine methyltransferases in cancer therapy:From epigenetic regulation to selective drugs

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Journal of Pharmaceutical Analysis 2023年第2期13卷 127-141页

作者： Qili liao Jie Yang Shengfang Ge Peiwei Chai jiayan Fan Renbing jia Department of Ophthalmology Ninth People's HospitalShanghai Jiao Tong University School of MedicineShanghai200001China Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology Shanghai200001China

The reversible and precise temporal and spatial regulation of histone lysine methyltransferases(KMTs)is essential for epigenome *** dysregulation of KMTs is associated with tumor initiation,metastasis,chemoresistance,invasiveness,and the immune ***,their promising effects are being evaluated in diversified preclinical and clinical trials,demonstrating encouraging outcomes in multiple *** this review,we have updated recent understandings of KMTs'functions and the development of their targeted ***,we provide an updated overview of the regulatory roles of several KMT activities in oncogenesis,tumor suppression,and immune *** addition,we summarize the current targeting strategies in different cancer types and multiple ongoing clinical trials of combination therapies with KMT *** summary,we endeavor to depict the regulation of KMT-mediated epigenetic landscape and provide potential epigenetic targets in the treatment of cancers.

关键词： Cancer Epigenetics Histone lysine methyltransferase Epigenetic inhibitors Combined therapeutic strategy Clinical application

Identification of a pleiotropic QTL cluster for Fusarium head blight resistance,spikelet compactness,grain number per spike and thousand-grain weight in common wheat

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The Crop Journal 2023年第2期11卷 672-677页

作者： Wenjing Hu Derong Gao Sen liao Shunhe Cheng Jizeng jia Weigang Xu Key Laboratory of Wheat Biology and Genetic Improvement for Low&Middle Yangtze Valley Ministry of Agriculture and Rural AffairsLixiahe Institute of Agricultural SciencesYangzhou 225007JiangsuChina Henan Agricultural University/Collaborative Innovation Center of Henan Grain Crops Zhengzhou 450002HenanChina Institute of Crop Sciences Chinese Academy of Agricultural SciencesBeijing 100081China Institute of Crop Molecular Breeding/National Engineering Laboratory of Wheat/Key Laboratory of Wheat Biology and Genetic Breeding in Central Huanghuai Area/Ministry of Agriculture/Henan Key Laboratory of Wheat Germplasm Resources Innovation and Improvement Henan Academy of Agricultural SciencesZhengzhou 450002HenanChina

Simultaneously improving Fusarium head blight(FHB)resistance and grain yield is challenging in wheat *** correlations between spikelet compactness(SC),grain number per spike(GNS),thousandgrain weight(TGW)and FHB resistance remains unclear in common *** of major quantitative trait loci(QTL)conferring FHB resistance and yield components,and development of breeder-friendly markers for the QTL are prerequisites for marker-assisted selection(MAS).Here,a recombinant inbred line(RIL)population derived from a cross between a resistant cultivar Yangmai 12(YM12)and a susceptible cultivar Yanzhan 1(YZ1)was used to map QTL for FHB resistance and yield components.A total of 22 QTL were identified;among these,six are likely to be new for corresponding traits.A QTL cluster(***-2D)for FHB type II resistance,SC,GNS,and TGW was detected on chromosome ***-friendly kompetitive allele-specific PCR(KASP)markers flanking the interval of ***-2D were developed and validated in a diverse panel of 166 wheat cultivars and advanced *** YM12 alleles of ***-2D significantly increased FHB resistance,SC,and GNS but decreased TGW in the validation *** KASP markers developed for ***-2D have great potential for breeding high-yielding wheat cultivars with enhanced FHB resistance.

关键词： Fusarium graminearum KASP marker QTL cluster Triticum aestivum

Slow magnetic relaxation and photoluminescence behaviors of dilanthanide complexes bearing N_(8)O_(2)donor macrocyclic ligand

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Journal of Rare Earths 2024年第7期42卷 1298-1303,I0004页

作者： Pei-Yu liao Yu-Quan Qi Zhen Li jian-Hua jia Ming-Liang Tong Key Laboratory of Bioinorganic and Synthetic Chemistry of Ministry of Education School of ChemistrySun Yat-Sen UniversityGuangzhou510006China

On account of the complicated magnetic exchange interactions between lanthanide ions,binuclear lanthanide complexes have broad application prospect in the field of single-molecule ***,it is necessary to develop reasonable bridging ligands to manipulate the directional assembly of binuclear lanthanide ***,we selected the macrocyclic ligand L^(N_(8)O_(2))to build up two new dilanthanide complexes[Ln_(2)(LN_(8)O_(2))(OpyO)_(2)(H_(2)O)2](NO_(3))_(2)(1-Ln,Ln=Dy,Tb;LN_(8)O_(2)=hexamethyl-tetraaza-dioxe-dipyrazolacycloicosaphane-2,9,12,19-tetraene;OpyOH=2-pyridinol-1-oxide).Dynamic magnetic studies show that 1-Dy exhibits slow relaxation behavior under a 1 kOe applied *** fitting analysis of relaxation times gives the effective energy barrier of 38.2 cm^(−1),and reveals that the slow magnetic relaxation behavior is dominated by the Orbach and Raman ***-resolution luminescence emission spectrum indicates the energy gap of 36.8 cm^(−1)between the ground state and the first excited state,consistent with the magnetic measurement results.1-Tb exhibits brilliant characteristic green light emission under UV light *** absolute quantum yield of 1-Tb is 44.8%,and its first-order fitted decay lifetime is 779.21μs at room *** study provides the way for directional construction of high-performance molecular materials with magnetic and optical dual-function.

关键词： Dilanthanide complexes Single-molecule magnets Macrocyclic ligand Photoluminescence behavior Rare earths

Population dynamics and habitat use of the Black-necked Crane (Grus nigricollis) in the Yarlung Tsangpo River basin, Tibet, China

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Avian Research 2019年第3期10卷 366-373页

作者： ru jia Tian Ma Fengjiang Zhang Guogang Zhang Dongping Liu Jun Lu Research Institute of Forest Ecology Environment and ProtectionChinese Academy of ForestryBeijing 100091China Key Laboratory of Forest Protection of State Forestry and Grassland Administration Beijing 100091China National Bird Banding Center of China Beijing 100091China Wildlife Conservation and Disease Surveillance Center of liaoning Province Dalian 116000China

Background:The Black-necked Crane (Grus nigricollis)is an internationally threatened crane living on the plateau, mainly in winter, in the Yarlung Tsangpo River basin in Tibet,western China. In the past five years,some economic development projects have been conducted in this area,posing potential threats to the wintering populations of the cranes and their habitats. Therefore, the current population dynamics of wintering Black-necked Cranes and habitat suitability in the Yarlung Tsangpo River basin were investigated. Methods: Twenty counties were surveyed using the line transect method in December 2017 and January 2018, and we recorded the location,flock size,number of individuals,habitat types and presence of human disturbance in which they *** compared the results from the middle wintering period in this survey with those from 2014. Results: The highest number of cranes recorded was 8291,and the results showed that the cranes were mainly distributed in Lhaze, Namling, Samzhubze, and Lhunzub.A total of 577 and 495 flocks were recorded in the early and middle wintering periods, respectively. In the early wintering period,there were signi ficant differences in the number of individuals across the di fferent habitats,with crop stubble land and plowed land representing more than 30% of the total habitat *** the middle wintering period, there were also signi ficant differences in the number of individuals, and the utilization of crop stubble land represented over 60% of the total. Conclusions: Wintering Black-necked Cranes mainly fed on spilled grains in stubble habitat after harvest. In the middle wintering period, some of the farmlands were plowed and irrigated,which resulted in food shortages in these areas,and the cranes tended to gather in mixed flocks of large size instead of as a single *** were still considerable regional wintering populations decreases in Quxu,Nedong,and Sakya in 2018 compared with 2014,and these decreases were main

关键词： Black-necked Crane Habitat use Population dynamics Tibet Yarlung Tsangpo River basin

Simultaneous Bulk-and Surface-initiated Living Polymerization Studied with a Heterogeneous Stochastic Reaction Model

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Chinese Journal of Polymer Science 2024年第3期42卷 364-372,I0008页

作者： jia-Shu Ma Zhi-Ning Huang jia-Hao Li Bang-Ping jiang Yan-Da liao Shi-Chen Ji Xing-Can Shen State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources(Ministry of Education of China)School of Chemistry and Pharmaceutical SciencesGuangxi Normal UniversityGuilin 541004China School of Computer Science and Engineering&School of Software Guangxi Normal UniversityGuilin 541004China

To better characterize the properties of surface-initiated polymers, simultaneous bulk-and surface-initiated polymerizations are usually carried out by assuming that the properties of the surface-initiated polymers resemble those of the bulk-initiated polymers. Through a Monte Carlo simulation using a heterogeneous stochastic reaction model, it was discovered that the bulk-initiated polymers exhibit a higher molecular weight and a lower dispersity than the corresponding surface-initiated polymers, which indicates that the equivalent assumption is invalid. Furthermore, the molecular weight distributions of the two types of polymers are also different, suggesting different polymerization mechanisms. The results can be simply explained by the heterogeneous distributions of reactants in the system. This study is helpful to better understand surface-initiated polymerization.

关键词： Surface-initiated polymerization Polymer brush Stochastic reaction model Heterogeneous polymerization Simultaneous polymerization