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Growth indices of seeds(maize and cowpea)grown in heavy metal contaminated soil treated with ginger extract

Toxicology Advances 2023年第4期5卷 15-23页

作者： Tatah Verwiyeh Silas Ezeonu Chukwuma Stephen Moses Adondua Abah Abu Sunday Michael Umaru John Isaac roy Yohanna Emochone Faculty of Pure and Applied Sciences Federal University WukariWukariPMB 1020Taraba StateNigeria

The consumption of maize and cowpea in Africa and developing countries is high,owing to the fact that they are readily available,coupled the with nutritional benefits they *** loss has been seen in crops cultivated on heavy metal polluted soils as a consequence of alterations in physiological and biochemical *** study was aimed at assessing the growth indices of seeds(maize and cowpea)grown on heavy metal contaminated soil treated with ginger *** study adopted a Complete Randomized Design(CRD)in which growth indices of either maize or cowpea were examined from each crop type grown on soil without any pollutant or treatment and soils with metal pollutants;with or without treatment with ginger extracts in the individual *** were analyzed using *** results showed that ginger extract induced oxidative stress on cowpea after 10 days of cultivation with root length significantly(P≤0.05)higher on the normal control-G-M and+l-G which recorded 7.60 and 7.3 cm *** of growth indices noticed after 30 and 40 days of cowpea cultivation were variable showing least growth in leaf *** maize root(27.00 cm),shoot(8.85 cm)and leaf(25.25 cm)development were recorded in maize grown on soil without metal contamination but treated with ginger(+G-M-positive control)after days 10,40 and 40 after *** was observed that the soil contaminated with heavy metals affected the growth pattern of the crops thereby causing stunted growth,chlorosis,discoloration and *** could be concluded that cowpea performed better in shoot of both treated and untreated soils even though the values were not significantly different from that of root and leaf while maize showed a decrease in shoot even though the values for root and leaf were not significantly different.

关键词： contaminants cowpea ginger extract maize heavy metals antioxidant bioremediation

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毛冬青质量标准的改进研究

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药物分析杂志 2019年第8期39卷 1416-1424页

作者：王怀友汪成郑玉忠邓伟麟段然董婷霞詹华强香港科技大学深圳研究院深圳市可食用及药用资源研究重点实验室深圳518057 香港科技大学生命科学部暨中药研发中心香港韩山师范学院潮州521041

目的:完善毛冬青药材质量标准,提高其质量控制水平。方法:采用《中华人民共和国药典》2015年版四部相关方法,对毛冬青药材的水分、灰分、浸出物(水溶性和醇溶性)及有害物质含量进行测定。采用显微鉴别法对毛冬青药材的根、茎及粉末进行... 详细信息

目的:完善毛冬青药材质量标准,提高其质量控制水平。方法:采用《中华人民共和国药典》2015年版四部相关方法,对毛冬青药材的水分、灰分、浸出物(水溶性和醇溶性)及有害物质含量进行测定。采用显微鉴别法对毛冬青药材的根、茎及粉末进行鉴别,并建立毛冬青药材薄层色谱及指纹图谱鉴别方法。同时以冬青素A为指标成分,建立毛冬青中冬青素A的HPlC含量测定方法。结果:毛冬青横切面和粉末的显微特征明显,薄层色谱斑点清晰,冬青素A分离较好;以冬青素A为参照峰,通过比较10批毛冬青药材的HPlC图谱中共有峰,确定了5个共有特征峰,建立了毛冬青药材的HPlC指纹图谱;冬青素A质量浓度在25~400 mg·l^-1范围内线性关系良好,线性回归方程为Y=5 882X+19 706(R^2=0.999 9,n=5),平均回收率为95.5%(RSD=3.1%,n=5)。10批毛冬青的水分为5.79%~7.43%,总灰分为1.00%~2.36%,酸不溶性灰分为0.20%~0.57%,水溶性浸出物为3.41%~10.18%,醇溶性浸出物为5.81%~15.33%,冬青素A含量为0.11%~1.56%。建议规定毛冬青的水分限度≤8.00%,总灰分限度≤2.50%,酸不溶性灰分≤0.50%,水溶性浸出物限度≥4.00%,醇溶性浸出物限度≥7.00%,以干燥品计,冬青素A的含量≥0.26%。结论:本研究完善和改进了毛冬青药材的质量控制方法。

关键词：毛冬青冬青素A 质量标准薄层色谱鉴别指纹图谱鉴别高效液相色谱含量测定

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Hydro-Sedimentary Dynamics of the Grand-Popo lagoon located Upstream of the Mobile Embouchure “Bouche du roy” in South-Western Benin

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Journal of Geoscience and Environment Protection 2021年第11期9卷 98-112页

作者： Honorin Gbinibou Andemi Gérard A. F. d’Almeida Moussa Bio Djara léandre Accalogoun Rodrigue A. Adechina Christophe Kaki laboratory of Geology Mines & Environment (Labo GME) Department of Earth Sciences (DES) University of Abomey-Calavi Cotonou Benin ACl Consultant: General Engineering Design Office Cotonou Benin

The problems of flooding, bank erosion and even the breaching of the barrier beach by the Grand-Popo lagoon are a concern in the south-western Beninese river-lagoon complex. The present study aims to improve the knowledge of the factors controlling the hydro-sedimentary functioning of this lagoon of Grand-Popo. It was based on bathymetric and sedimentological studies and the analysis of physical-chemical parameters of the water and allowed to know the morphology of the lagoon bottom and the distribution of sedimentary facies according to the intensity of the water current. The salinity of the lagoon waters shows a west-east gradient passing thus from 0‰ to 0.78‰ in the main direction of flow. Over the whole lagoon system, the average liquid flows vary from -38.499 to 159.13 m3/s. The bathymetry indicates depths varying from 0.4 to 6.5 m, revealing type V and type U lagoon bottoms which reflect acute bottom concavities marked by hollowing under the effect of strong currents or by sandy terraces resulting from the continuous input of sediments carried by the Mono River. These sediments are heterogeneously distributed in the lagoon bottom and vary from free sand to mud. Given the complexity of the factors that control the hydro-sedimentary functioning of the Grand-Popo lagoon, it is recommended that periodic hydrological and bathymetric monitoring be carried out to locate exceptional variations in water levels to prevent not only the risks of overflowing lagoon waters and the flooding that follows but also spectacular erosion of the lagoon banks.

关键词： Grand-Popo lagoon Hydro-Sedimentary Functioning lagoon Bottoms Sediments

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Nature:研究首次证实帕金森病部分上是一种自身免疫疾病

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现代生物医学进展 2017年第27期17卷 I0002-I0002页

作者： David Sulzer, Francesca Garretti, Ellen Kanter, Julian Agin-liebes, Elizabeth Phillips, Simon Mallal David Sulzer, roy N. Alcalay, lucien Cote, Christopher liong, Elizabeth Phillips, Simon Mallal David Sulzer Curtis McMurtrey, William H. Hildebrand Xiaobo Mao, Valina l. Dawson, Ted M. Dawson Xiaobo Mao, Valina l. Dawson, Ted M. Dawson Valina l. Dawson Valina l. Dawson, Ted M. Dawson Ted M. Dawson Carla Oseroff, John Pham, John Sidney, Myles B. Dillon, Chelsea Carpenter, Daniela Weiskopf, Bjoern Peters, April Frazier, Cecilia S. lindestam Arlehamn, Alessandro Sette Elizabeth Phillips, Simon Mallal Departments of Psychiatry Columbia University Division of Molcular Therapeutics New York State Psychiatric Institute New York New York 10032 USA Department of Neurology Columbia University New York New York 10032 USA Department of Pharmacology Columbia University New York New York 10032 USA Department of Microbiology and Immunology University of Oklahoma Oklahoma City Oklahoma 73104 USA Neuroregeneration and Stem Cell Program Institute for Cell Engineering and the Department of Neurology Johns Hopkins University School of Medicine Baltimore Maryland 21205 USA Adrienne Helis Malvin Medical Research Foundation New Orleans Louisiana 70130-2685 USA Department of Physiology Johns Hopkins University School of Medicine Baltimore Maryland 21205 USA Solomon H. Snyder Department of Neuroscience Johns Hopkins University School of Medicine Baltimore Maryland 21205 USA Department of Pharmacology & Molecular Sciences Johns Hopkins University School of Medicine Baltimore Maryland 21205 USA Division of Vaccine Discovery La Jolla Institute for Allergy and Immunology La Jolla California 92037 USA Institute for Immunology and Infectious Diseases Murdoch University Perth Western Australia 6150 Australia Vanderbilt University School of Medicine Nashville Tennessee 37235 USA

帕金森病是一种神经退行性疾病。这种疾病的一种关键特征是受损的a-突触核蛋白（alpha-synuclein）在帕金森病患者体内的一种被称作多巴胺能神经元的脑细胞中堆积。在一项新的研究中，来自美国哥伦比亚大学医学中心和拉荷亚过敏症与免... 详细信息

帕金森病是一种神经退行性疾病。这种疾病的一种关键特征是受损的a-突触核蛋白（alpha-synuclein）在帕金森病患者体内的一种被称作多巴胺能神经元的脑细胞中堆积。在一项新的研究中，来自美国哥伦比亚大学医学中心和拉荷亚过敏症与免疫学研究所等研究机构的研究人员发现首个直接的证据证实自身免疫反应在帕金森病中发挥着作用。

关键词：自身免疫疾病帕金森病神经退行性疾病多巴胺能神经元哥伦比亚大学免疫反应研究人员研究机构

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A history of high-power laser research and development in the United Kingdom

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High Power laser Science and Engineering 2021年第2期9卷 41-126页

作者： Colin N.Danson Malcolm White John R.M.Barr Thomas Bett Peter Blyth David Bowley Ceri Brenner Robert J.Collins Neal Croxford A.E.Bucker Dangor laurence Devereux Peter E.Dyer Anthony Dymoke-Bradshaw Christopher B.Edwards Paul Ewart Allister I.Ferguson John M.Girkin Denis R.Hall David C.Hanna Wayne Harris David I.Hillier Christopher J.Hooker Simon M.Hooker Nicholas Hopps Janet Hull David Hunt Dino A.Jaroszynski Mark Kempenaars Helmut Kessler Sir Peter l.Knight Steve Knight Adrian Knowles Ciaran l.S.lewis Ken S.lipton Abby littlechild John littlechild Peter Maggs Graeme P.A.Malcolm OBE Stuart P.D.Mangles William Martin Paul McKenna Richard O.Moore Clive Morrison Zulfikar Najmudin David Neely Geoff H.C.New Michael J.Norman Ted Paine Anthony W.Parker Rory R.Penman Geoff J.Pert Chris Pietraszewski Andrew Randewich Nadeem H.Rizvi Nigel Seddon MBE Zheng-Ming Sheng David Slater Roland A.Smith Christopher Spindloe roy Taylor Gary Thomas John W.G.Tisch Justin S.Wark Colin Webb S.Mark Wiggins Dave Willford Trevor Winstone AWE Aldermaston ReadingUK Oxford Centre for High Energy Density Science Department of PhysicsClarendon LaboratoryUniversity of OxfordOxfordUK Centre for Intertial Fusion Studies Blackett LaboratoryImperial College LondonLondonUK Formerly of Electrox LetchworthUK Formerly of Central laser Facility Rutherford LaboratoryDidcotUK Formerly of Ferranti Defence Systems LincolnUK leonardo EdinburghUK Retired AWEReadingUK Formerly of AWE ReadingUK Formerly of laser lines ltd BanburyUK Formerly of Optilas ltd Milton KeynesUK Retired Pro-Lite TechnologyCranfieldUK Specialised Imaging ltd PitstoneUK Central laser Facility STFC Rutherford Appleton LaboratoryDidcotUK Magna-Power Electronics ltd ReadingUK DeBe lasers Needham Laser TechnologiesWhitchurchUK Blackett laboratory Imperial College LondonLondonUK SPIE Europe CardiffUK Professor Emeritus(Physics) University of HullKingston upon HullUK Kentech Instruments ltd WallingfordUK Department of Physics Clarendon LaboratoryUniversity of OxfordOxfordUK Professor Emeritus Department of PhysicsUniversity of StrathclydeGlasgowUK Department of Physics Durham UniversityDurhamUK Professor Emeritus(Photonics) Heriot-Watt UniversityEdinburghUK Professor Emeritus University of SouthamptonSouthamptonUK Optical Surfaces ltd KenleyUK JEH lasers ltd RugbyUK Scottish Universities Physics Alliance Department of PhysicsUniversity of StrathclydeGlasgowUK ITER Organization Saint-Paul-lez-DuranceFrance Manx Precision Optics ltd BallasallaUK laser lines ltd BanburyUK Elliot Scientific ltd MetroTest Scientific GroupHarpendenUK Centre for Plasma Physics Queen’s University BelfastBelfastUK Retired Founderand former MDRofin-Sinar UK LtdHullUK Heraeus Noblelight ltd CambridgeUK Mirli Books ChelmsfordUK M Squared lasers ltd GlasgowUK University of Hertfordshire HatfieldUK E&EO UK ltd Barton-upon-HumberUK Department of Physics University of YorkYorkUK IC Optical Systems ltd BeckenhamUK laser Micromachining ltd St AsaphUK MBDA UK ltd Brist

The first demonstration of laser action in ruby was made in 1960 by *** of Hughes Research laboratories,*** laboratories worldwide began the search for lasers using different materials,operating at different *** the UK,academia,industry and the central laboratories took up the challenge from the earliest days to develop these systems for a broad range of *** historical review looks at the contribution the UK has made to the advancement of the technology,the development of systems and components and their exploitation over the last 60 years.

关键词： high-power lasers history United Kingdom

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英国婴儿痉挛研究中心进行的多中心随机对照试验:用药14d时氨己烯酸与去氢氢化可的松和替可克肽的药效对比

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世界核心医学期刊文摘（儿科学分册） 2005年第4期1卷 6-7页

作者： lux A.l. Edwards Hancock E. J.P.Osborne 李开 roy.U.Hosp.Bath NHS Trust Sch. H. University of BathBathUnited Kingdom

研究背景:婴儿痉挛症为婴儿的一种严重癫痫性疾病,死亡率高且难治疗。既往几十年中,激素疗法(促肾上腺皮质激素和去氢氢化可的松)已成为主要的治疗方法,但却很少有证据支持此疗法。据记载,氨己烯酸对此病有效。目的:氨己烯酸与去氢化可... 详细信息

研究背景:婴儿痉挛症为婴儿的一种严重癫痫性疾病,死亡率高且难治疗。既往几十年中,激素疗法(促肾上腺皮质激素和去氢氢化可的松)已成为主要的治疗方法,但却很少有证据支持此疗法。据记载,氨己烯酸对此病有效。目的:氨己烯酸与去氢化可的松和替可克肽均可治疗婴儿痉挛症,本文对比分析两类药物的治疗效果。方法:本研究为多中心随机对照试验,在英国150所医院进行,由英国婴儿痉挛研究中心评测结果。以用药第13和14天时痉挛停止作为有效治疗结果指标。

关键词：氨己烯酸婴儿痉挛随机对照试验癫痫性研究中心去氢激素疗法癫痛 seizure 结果指标

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注射对比剂和覆膜支架植入术对CT腹主动脉瘤半自动分割体积测量的可重复性的影响

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国际医学放射学杂志 2014年第5期 495-495页

作者： F.Morin-roy C.Kauffmann A.Tang S.Hadjadj O.Thomas N.Piché 梁雪 Department of Radiology Centre Hospitalier Universitaire de Montréal(CHUM)H?pital Notre-Dame1560 Sherbrooke EstMontréalQuébecCanadaH2L 4M1

摘要目的评估注射对比剂以及覆膜支架植入术对使用分割软件测量腹主动脉瘤的体积与最大直径的可行性、准确性和可重复性的影响。方法 80 例腹主动脉瘤病人的 CT

关键词：腹主动脉瘤可重复性支架植入术覆膜 CT

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Notes,outline and divergence times of Basidiomycota

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Fungal Diversity 2019年第6期99卷 105-367页

作者： Mao-Qiang He Rui-lin Zhao Kevin D.Hyde Dominik Begerow Martin Kemler Andrey Yurkov Eric H.C.McKenzie Olivier Raspe Makoto Kakishima Santiago Sanchez-Ramırez Else C.Vellinga roy Halling Viktor Papp Ivan V.Zmitrovich Bart Buyck Damien Ertz Nalin N.Wijayawardene Bao-Kai Cui Nathan Schoutteten Xin-Zhan liu Tai-Hui li Yi-Jian Yao Xin-Yu Zhu An-Qi liu Guo-Jie li Ming-Zhe Zhang Zhi-lin ling Bin Cao Vladimir Antonin Teun Boekhout Bianca Denise Barbosa da Silva Eske De Crop Cony Decock Balint Dima Arun Kumar Dutta Jack W.Fell Jozsef Geml Masoomeh Ghobad-Nejhad Admir J.Giachini Tatiana B.Gibertoni Sergio P.Gorjon Danny Haelewaters Shuang-Hui He Brendan P.Hodkinson Egon Horak Tamotsu Hoshino Alfredo Justo Young Woon lim Nelson Menolli Jr Armin Mesic Jean-Marc Moncalvo Gregory M.Mueller la szlo G.Nagy RHenrik Nilsson Machiel Noordeloos Jorinde Nuytinck Takamichi Orihara Cheewangkoon Ratchadawan Mario Rajchenberg Alexandre G.S.Silva-Filho Marcelo Aloisio Sulzbacher Zdenko Tkalcec Ricardo Valenzuela Annemieke Verbeken Alfredo Vizzini Felipe Wartchow Tie-Zheng Wei Michael WeiB Chang-lin Zhao Paul M.Kirk State Key laboratory of Mycology Institute of MicrobiologyChinese Academy of SciencesBeijing 100101People’s Republic of China Department of Entomology and Plant Pathology Faculty of AgricultureChiang Mai UniversityChiang Mai 50200Thailand Center of Excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand College of life Sciences University of Chinese Academy of SciencesHuairou DistrictBeijing 100408People’s Republic of China Ruhr-Universitat Bochum AG GeobotanikND03UniversitatsstraBe 15044801 BochumGermany leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures InhoffenstraBe 7B38124 BrunswickGermany Manaaki Whenua-landcare Research Private Bag 92170AucklandNew Zealand Research Department Meise Botanic GardenNieuwelaan 381860 MeiseBelgium Service General de l'Enseignement superieur et de la Recherche scientifique Federation Wallonie-BruxellesLavallee 11080 BrusselsBelgium University of Tsukuba TsukubaIbaraki 305-8572Japan Department of Ecology and Evolutionary Biology University of Toronto25 Willcocks St.TorontoON M5S 3B2Canada Berkeley USA Institute of Systematic Botany The New York Botanical GardenBronxNY 10458-5126USA Department of Botany Szent Istvan University1518 BudapestHungary Komarov Botanical Institute Russian Academy of SciencesProfessor Popov st.2Saint PetersburgRussia 197376 Institut pour Systematique Ecologie Biodiversite(ISYEB UMR 7205) Sorbonne universiteMuseum National d’Histoire Naturelle CP 39CNRSDepartement Origines et Evolution12 Rue Buffon75005 ParisFrance Institute of Microbiology Beijing Forestry UniversityBeijing 100083People’s Republic of China Department of Biology Research Group MycologyGhent UniversityK.L.Ledeganckstraat 359000 GhentBelgium State Key laboratory of Applied Microbiology Southern China Guangdong Provincial Key Laboratory of Microbial Culture Collection and ApplicationGuangdong Institute of MicrobiologyGuangzhou 510070People’s Republic of China Department of Botany Moravian Mu

The Basidiomycota constitutes a major phylum of the kingdom Fungi and is second in species numbers to the *** present work provides an overview of all validly published,currently used basidiomycete genera to date in a single *** outline of all genera of Basidiomycota is provided,which includes 1928 currently used genera names,with 1263 synonyms,which are distributed in 241 families,68 orders,18 classes and four *** provide brief notes for each accepted genus including information on classification,number of accepted species,type species,life mode,habitat,distribution,and sequence ***,three phylogenetic analyses with combined lSU,SSU,5.8s,rpb1,rpb2,and ef1 datasets for the subphyla Agaricomycotina,Pucciniomycotina and Ustilaginomycotina are conducted,*** time estimates are provided to the family level with 632 species from 62 orders,168 families and 605 *** study indicates that the divergence times of the subphyla in Basidiomycota are 406-430 Mya,classes are 211-383 Mya,and orders are 99-323 Mya,which are largely consistent with previous *** this study,all phylogenetically supported families were dated,with the families of Agaricomycotina diverging from 27-178 Mya,Pucciniomycotina from 85-222 Mya,and Ustilaginomycotina from 79-177 *** times as additional criterion in ranking provide additional evidence to resolve taxonomic problems in the Basidiomycota taxonomic system,and also provide a better understanding of their phylogeny and evolution.

关键词： Classification Molecular clock Fungi Systematics Taxonomy

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内源性CD34＋脂肪干细胞在提高人类脂肪移植效果持久性中的优势：一项异种移植模型

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中国美容整形外科杂志 2014年第4期25卷 I0016-I0016页

作者： Brian J. Philips Tara l. Grahovac Jolene E. Valentin Christopher W. Chung Jacqueline M. Bliley Melanie E. Pfeifer Sohini B. roy Stephanie Dreifuss Arta Kelmendi-Doko Russell E. Kling SudheerK. Ravuri Kacey G. Marra Vera S. Donnenberg Albert D. Donnenberg J. Peter Rubin 魏峰高景恒张晨美国宾夕法尼亚州匹兹堡匹兹堡大学整形外科与生物工程部匹兹堡大学癌症中心 McGowan再生医学研究中心《中国美容整形外科杂志》编辑部大连大学附属新华医院整形外科

背景与目的脂肪移植是一项很有前景的软组织填充增大技术，但移植疗效持久性存在高度不可预知性，而且影响移植成活率的因素尚未明确。因为具有分化的潜能和释放生长因子的能力，脂肪来源干细胞（adipose-derivedstemcells，ADSCs）可... 详细信息

背景与目的脂肪移植是一项很有前景的软组织填充增大技术，但移植疗效持久性存在高度不可预知性，而且影响移植成活率的因素尚未明确。因为具有分化的潜能和释放生长因子的能力，脂肪来源干细胞（adipose-derivedstemcells，ADSCs）可在移植修复过程中起关键作用。我们旨在确定ADSCs在人体脂肪中呈现的生物学特性是否与移植体积的体内效果保持存在关联。方法利用标准的离心分离技术对从8例人体受术者获取的脂肪抽吸物进行处理，然后将其注射至6周龄无胸腺裸鼠躯体两侧。测量移植物的质量和体积，于移植后8周进行包含针对血管的CD31^＋染色的组织学评估。从各供体脂肪抽吸物中分离获取基质血管细胞群（stromalvascularfraction，SVF），利用多参数流式细胞术对其表面标记物进行分析，并对其增值、分化能力和正常含氧量／低含氧量血管内皮细胞生长因子（vas—cularendothelialgrcwlhfactor，VEGF）的分泌情况进行实验研究。结果从不同供体中获取的SVF，其CD34^＋祖细胞含量百分率存在较大差异，其平均值为21．3％±15．O％（X±s）。SVF细胞的增殖速率和成脂潜能在不同供体间存在较为中等差异。在小鼠异种移植研究中，移植后8周体积保存的量约为36％～68％，总体平均值为52％±11％。SVF中CD34^＋祖细胞的含量与脂肪移植效果持久性方面存在较强的关联（P〈0．05）。结论在不同患者之间，其脂肪组织的内在生物学特性存在差异。特别是SVF中CD34^＋祖细胞的浓度可能是影响脂肪移植持久性的因素之一。

关键词：异种移植模型疗效持久性脂肪干细胞脂肪移植血管内皮细胞生长因子 CD34+ CD34^+祖细胞内源性

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重叠低剖面可视化腔内支撑装置治疗颈内动脉血泡样动脉瘤的效果分析

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医学研究生学报 2018年第3期31卷 235-238页

作者：文立利张鑫张庆荣吴琪陈姝娟邓金龙吕盛银邵将王汉东南京大学医学院附属金陵医院(南京军区南京总医院)神经外科南京医学博士研究生210002

目的目前关于重叠低剖面可视化腔内支撑装置(lVIS)支架治疗颈内动脉血泡样动脉瘤(BBA)的报道较少。文中旨在对应用重叠lVIS支架辅助弹簧圈栓塞与其他支架辅助弹簧圈栓塞治疗BBA的效果进行了回顾性的分析。方法回顾性分析2015年2月至2017... 详细信息

目的目前关于重叠低剖面可视化腔内支撑装置(lVIS)支架治疗颈内动脉血泡样动脉瘤(BBA)的报道较少。文中旨在对应用重叠lVIS支架辅助弹簧圈栓塞与其他支架辅助弹簧圈栓塞治疗BBA的效果进行了回顾性的分析。方法回顾性分析2015年2月至2017年2月南京军区南京总医院神经外科诊断为BBA并进行血管内介入治疗的15例患者资料。11例患者采用重叠lVIS支架辅助弹簧圈栓塞,4例患者采用非重叠lVIS支架辅助弹簧圈栓塞。根据Raymond分级统计术后即刻、术后1周治疗效果。随访时间2015年4月1日至2017年10月1日,分析影像学和临床随访结果。结果术后即刻闭塞情况:重叠lVIS支架辅助弹簧圈栓塞患者1级10例、3级1例;非重叠lVIS支架辅助弹簧圈栓塞患者1级3例、2级1例。术后1周闭塞情况:重叠lVIS支架辅助弹簧圈栓塞患者1级11例;非重叠lVIS支架辅助弹簧圈栓塞患者1级2例、2级2例。影像学随访结果:最后1次DSA随访闭塞情况,重叠lVIS支架辅助弹簧圈栓塞患者1级9例,2级1例;非重叠lVIS支架辅助弹簧圈栓塞患者1级1例、2级2例、3级1例。临床随访结果:重叠lVIS支架辅助弹簧圈栓塞患者mRS 0分9例、1分2例;非重叠lVIS支架辅助弹簧圈栓塞mRS 0分3例、1分1例;15例患者均预后良好。结论重叠lVIS支架辅助弹簧圈栓塞技术治疗BBA安全有效,值得临床推广。

关键词：颈内动脉血泡样动脉瘤血管内治疗支架低剖面可视化腔内支撑装置预后

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