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Extrahepatic cholangiocarcinoma:Current status of endoscopic approach and additional therapies

World Journal of Hepatology 2021年第2期13卷 166-186页

作者： Alina Ioana Tantau Alina Mandrutiu Anamaria Pop roxana delia zaharie Dana Crisan Carmen Monica Preda Marcel Tantau Voicu Mercea Department of Internal Medicine and Gastroenterology “Iuliu Hatieganu”University of Medicine and Pharmacy4th Medical ClinicCluj-Napoca 400012ClujRomania Department of Gastroenterology and Hepatology Gastroenterology and Hepatology Medical CenterCluj-Napoca 400132ClujRomania Department of Gastroenterology “Prof.Dr.Octavian Fodor”Regional Institute of Gastroenterology and HepatologyCluj-Napoca 400162ClujRomania Department of Gastroenterology “Iuliu Hatieganu”University of Medicine and PharmacyCluj-Napoca 400012ClujRomania Internal Medicine Department Cluj-Napoca Internal Medicine Department“Iuliu Hatieganu”University of Medicine and Pharmacy5th Medical ClinicCluj-Napoca 400012ClujRomania Department of Gastroenterology and Hepatology Clinic Fundeni Institute“Carol Davila”University of Medicine and PharmacyBucharest 22328Romania Department of Internal Medicine and Gastroenterology “Prof.Dr.Octavian Fodor”Regional Institute of Gastroenterology and HepatologyCluj-Napoca 400162ClujRomania Department of Internal Medicine and Gastroenterology “Iuliu Hatieganu”University of Medicine and PharmacyCluj-Napoca 400012ClujRomania

The prognosis of patients with advanced or unresectable extrahepatic cholangiocarcinoma is *** than 50%of patients with jaundice are inoperable at the time of first *** treatment in patients with obstructive jaundice ensures bile duct drainage in preoperative or palliative *** of symptoms(pain,pruritus,jaundice)and improvement in quality of life are the aims of palliative *** implantation by endoscopic retrograde cholangiopancreatography is generally preferred for long-term *** is a vast variety of plastic and metal stents,covered or *** stent choice depends on the expected length of survival,quality of life,costs and physician *** review will provide the framework for the endoscopic minimally invasive therapy in extrahepatic ***,additional therapies,such as brachytherapy,photodynamic therapy,radiofrequency ablation,chemotherapy,molecular-targeted therapy and/or immunotherapy by the endoscopic approach,are the nonsurgical methods associated with survival improvement rate and/or local symptom palliation.

关键词： Cholangiocarcinoma Endoscopic drainage Endoscopic retrograde cholangiopancreatography Photodynamic therapy Radiofrequency ablation Brachytherapy

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Surgical management of hydatid cyst disease of the liver: An improvement from our previous experience?

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World Journal of Gastrointestinal Surgery 2023年第5期15卷 847-858页

作者： Florin zaharie Dan Valean roxana zaharie Calin Popa Emil Mois Diana Schlanger Alin Fetti Claudiu Zdrehus Andra Ciocan Nadim Al-Hajjar Department of Surgery “Octavian Fodor”Regional Institute of Gastroenterology and HepatologyCluj-Napoca 400636ClujRomania Department of Gastroenterology “Octavian Fodor”Regional Institute of Gastroenterology and HepatologyCluj-Napoca 400636ClujRomania Department of Gastroenterology “Iuliu Hatieganu”University of Medicine and PharmacyCluj-Napoca 400012ClujRomania Department of Anaesthesiology “Octavian Fodor”Regional Institute of Gastroenterology and HepatologyCluj-Napoca 400636ClujRomania

BACKGROUND Hydatid liver disease remains an important issue in endemic areas,which may require immediate *** laparoscopic surgery is on the rise,the presence of certain complications may require conversion to the open *** To compare the results of laparoscopic treatment and the open approach in the context of a 12-year single institution experience,and to perform a further comparison between results from the current study and those from a previous *** Between January 2009 and December 2020,247 patients underwent surgery for hydatic disease of the liver in our *** the 247 patients,70 underwent laparoscopic treatment.A retrospective analysis between the two groups was performed,as well as a comparison between current and previous laparoscopic experience(1999-2008).RESULTS There were statistically significant differences between the laparoscopic and open approaches regarding the cyst dimension,location,and presence of cystobiliary *** were no intraoperative complications in the laparoscopic *** cutoff value for the cyst size regarding the presence of cystobiliary fistula was 6.85 cm(P=0.001).CONCLUSION Laparoscopic surgery still plays an important role in the treatment of hydatid disease of the liver,with an increase in its usage over the course of years that has shown benefits regarding the postoperative recovery with a decreased rate of intraoperative *** experienced surgeons can perform laparoscopic surgery in the most difficult conditions,there are some selection criteria that need to be maintained for higher quality results.

关键词： Follow-up Cystobilliary communication Conversion Postoperative complications Imaging

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