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The power of prevention:how tenofovir and entecavir are changing the game in hepatocellular carcinoma

Hepatobiliary Surgery and Nutrition 2023年第6期12卷 936-940页

作者： Endrit Shahini rossella donghia Antonio Facciorusso Gastroenterology Unit National Institute of Gastroenterology-IRCCS“Saverio de Bellis”Castellana GrotteItaly Data Science Unit National Institute of Gastroenterology-IRCCS“Saverio de Bellis”Castellana GrotteItaly Gastroenterology Unit Department of Medical SciencesUniversity of FoggiaFoggiaItaly

Introduction Individual patient data(IPD)meta-analysis by Choi et al.(1)compared hepatocellular carcinoma(HCC)risk between the entecavir(ETV)and tenofovir(TDF)in treatment-naïve chronic hepatitis B(CHB)patients using a multivariable Cox proportional hazards model from 11 Asian studies,totaling 42,939 patients receiving nucles(t)tide analogues(NAs)for more than one year.

关键词： Hepatocellular carcinoma(HCC) liver cancer cirrhosis,hepatitis B virus(HBV)

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Comparison of perioperative parameters in one-handed rotational phacoemulsification versus conventional phacoemulsification and femtosecond laser-assisted cataract surgery

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International Journal of Ophthalmology(English edition) 2021年第12期14卷 1868-1875页

作者： Samuele Gigliola Giancarlo Sborgia Alfredo Niro Carmela Palmisano Pasquale Puzo Gianluigi Giuliani Luigi Sborgia Dario Sisto Valentina Pastore Claudio Furino rossella donghia Alessandra Sborgia Francesco Boscia Giovanni Alessio Eye Clinic Department of Medical ScienceNeuroscience and Sense OrgansUniversity of BariBari 70124Italy Eye Clinic Hospital“SS.Annunziata”ASL TarantoTaranto 74121Italy National Institute of Gastroenterology“S.de Bellis”Research Hospital Castellana Grotte 70013Italy

AIM:To compare perioperative parameters of one-handed rotational phacoemulsification technique(one-handed phaco-roll)with each of other two techniques,“Divide et Conquer”and femtosecond laser-assisted cataract surgery(FLACS)METHODS:In this retrospective and comparative cohort study,eyes with uncomplicated cataract(nuclear density grade 2 to 3)treated routinely with one-handed phacoroll(n=23;Group 1)or“Divide et Conquer”(n=23;Group 2)or FLACS(n=23;Group 3)were *** parameters including effective phaco-time(EPt),ultrasound time(USt),aspiration time,surgical time,phacoemulsification(phaco)-power,balanced salt solution(BSS)use,cumulative dissipated energy(CDE)were recorded and *** outcomes including best corrected visual acuity(BCVA),corneal endothelial cell density(ECD),endothelial cell loss(ECL),central corneal thickness(CCT)and central macular thickness(CMT),were assessed and compared pre-operatively and at 1mo after ***:Aspiration and surgical time,and BSS used were lower in Group 1(P<0.01)than other ***,phaco-power and CDE were lower in Group 1(P<0.05)than Group 2 but not significantly different from Group *** Group 1,USt was lower(P<0.05)than Group 2 but higher(P<0.05)than Group *** improved in all groups without significant difference between Group 1 and the other *** significant differences regarding all post-operative morphologic outcomes(ECD,ECL,CCT,CMT)were *** clinical complications ***:One-handed phaco-roll seems to be less time-consuming than“Divide et Conquer”and FLACS and less energy-consuming than“Divide et Conquer”.Furthermore,one-handed phaco-roll seems to have an equal safety profile compared to the other two techniques.

关键词： cataract surgery phaco-rolling onehanded phacoemulsification Divide et Conquer femtosecond laser-assisted cataract surgery

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