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Late Regularization of the Alveolar Ridge in a Patient with a Prosthesis and Special Needs: A Case Report

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Open Journal of Stomatology 2018年第11期8卷 305-311页

作者： Wilson Matsumoto Alexandre Elias Trivellato rossana pereira de almeida Antunes Cássio Edvard Sverzut Guilherme Spagnol Cristian Sbardelotto Takami Hirono Hotta department of dental Materials and Prosthodontics University of S&atilde o Paulo S&atilde o Paulo Brazil department of Oral and Maxillofacial Surgery and Periodontology University of S&atilde o Paulo S&atilde o Paulo Brazil department of dental Materials and Prostheses University of S&atilde o Paulo S&atilde o Paulo Brazil

Residual ridge shape is important for the seating of a prosthesis. The objective of this case report was to illustrate the importance of reduction maneuvers with regard to alveolar bone plates after multiple tooth extractions in patients with prostheses and special needs. In the current patient, there were difficulties during the adaptation and fitting of the upper denture. Bilateral bone resection was indicated in the molar buccal region. Late regularization of the alveolar ridge, which was accomplished in hospital, was necessary for the preparation, adaptation, and use of the denture. The general and systemic health care of the patient should be monitored throughout surgical intervention. Though tooth extractions are common procedures, particular attention is required to ensure adequate alveolar ridge remodeling that is conducive to oral rehabilitation.

关键词： Alveolar Ridge Adaptation denture Exostoses

The challenge of molecular selection in liver-limited metastatic colorectal cancer for surgical resection: a systematic review and meta-analysis in the context of current and future approaches

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Oncology Research 2024年第9期32卷 1407-1422页

作者： rossana RONCATO JERRY POLESEL FEdeRICA TOSI ELENA PERUZZI ERIKA BRUGUGNOLI CLAUDIA LAURIA PANTANO MARIA FURFARO FILIPPO DI GIROLAMO ALESSANDRO NANI ARIANNA PANI NOEMI MILAN ELENA de MATTIA ANDREA SARTORE-BIANCHI ERIKA CECCHIN Experimental and Clinical Pharmacology Unit Centro di Riferimento Oncologico di Aviano(CRO)IRCCSAviano33081Italy department of Medicine(DMED) University of UdineUdine33100Italy Unit of Cancer Epidemiology Centro di Riferimento Oncologico di Aviano(CRO)IRCCSAviano33081Italy department of Oncology and Hemato-Oncology Universitàdegli Studi di MilanoMilan20122Italy department of Hematology Oncologyand Molecular MedicineGrande Ospedale Metropolitano NiguardaMilan20122Italy Oncology Pharmacy Unit IRCCS Istituto Romagnolo per lo Studio dei Tumori Dino AmadoriMeldola47014Italy Pharmacy Unit Fondazione IRCCS Istituto Tumori di MilanoMilan20122Italy department of Pharmacy Ca’Foncello Treviso Regional HospitalPiazzale Ospedale 1Treviso31100Italy department of Medical Surgical and Health Sciences University of TriesteTrieste34127Italy Hospital Pharmacy Cattinara HospitalAzienda Sanitaria Universitaria Giuliano IsontinaTrieste34148Italy department of Oncology and Onco-Hematology Postgraduate School of Clinical Pharmacology and ToxicologyUniversity of MilanMilan20122Italy

Objectives:Treatment of metastatic colorectal cancer(mCRC)includes resection of liver metastases(LM),however,no validated biomarker identifies patients most likely to benefit from this *** meta-analysis aimed to assess the impact of the most relevant molecular alterations in cancer-related genes of CRC(i.e.,RAS,BRAF,SMAD4,PIK3CA)as prognostic markers of survival and disease recurrence in patients with mCRC surgically treated by LM ***:A systematic literature review was performed to identify studies reporting data regarding survival and/or recurrence in patients that underwent complete liver resection for CRC LM,stratified according to RAS,BRAF,PIK3CA,and SMAD4 mutational *** ratios(HRs)from multivariate analyses were pooled in the meta-analysis and various adjustment strategies for confounding factors were *** search was conducted in numerous databases,including MEDLINE(PubMed),Embase,Cumulative Index to Nursing and Allied Health Literature(CINAHL)(EBSCO host),and WHO Global Index Medicus,through March 18th,***-analyses,editorials,letters to the editor,case reports,studies on other primary cancers,studies with primary metastatic sites other than the liver,studies lacking specific oncological outcome variables or genetic data,non-English language studies,and studies omitting residual disease data from liver metastasectomy were *** remaining 47 studies were summarized in a descriptive table which outlines the key characteristics of each study and final results were graphically ***:RAS mutation status was negatively associated with overall survival(OS)(HR,1.68;95%CI,1.54–1.84)and recurrence free survival(RFS)(HR,1.46;95%CI,1.33–1.61).A negative association was also found for BRAF regarding OS(HR,2.64;95%CI,2.15–3.24)and RFS(HR,1.89;95%CI,1.32–2.73)and SMAD4 regarding OS(HR,1.93;95%CI,1.56–2.38)and RFS(HR,1.95;95%CI,1.31–2.91).For PIK3CA only three studies were eligible and no significant associati

关键词： Metastasectomy Liver metastases RAS BRAF SMAD4 PIK3CA Colorectal

Semiology:A Comparative Science of Institutions

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Language and Semiotic Studies 2022年第1期8卷 6-15页

作者： rossana de Angelis UniversitéParis-Est Créteil France

The Saussurian notion of semiology is closely linked to that of *** fact,in Saussure’s words,“systems of signs” are “social institutions”.Furthermore,language is conceived as a “special system” in relation to others “in the set of semiological facts”.Among different semiological systems,writing also occupies a special *** there is a real difference between language and writing,we could look for it in the power of externalization,which confers to writing a sort of exemplarity among the other *** we will see in this article,writing reveals the process of institutionalization itself,as well as the rational sociality of reasoning institutions and the irrational sociality of unreasoning institutions as ***,which is the discipline studying these phenomena and their differences,can be considered as a comparative science of institutions.

关键词： semiology language writing institution signs systems

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建筑学报 2024年第7期 76-81页

作者：无郭锡恩胡如珊陈颢(摄影) 如恩设计研究室不详

Static Analysis of Doubly-Curved Shell Structures of Smart Materials and Arbitrary Shape Subjected to General Loads Employing Higher Order Theories and Generalized Differential Quadrature Method

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Computer Modeling in Engineering & Sciences 2022年第12期133卷 719-798页

作者： Francesco Tornabene Matteo Viscoti rossana Dimitri department of Innovation Engineering School of EngineeringUniversity of SalentoLecce73100Italy

The article proposes an Equivalent Single Layer(ESL)formulation for the linear static analysis of arbitrarily-shaped shell structures subjected to general surface loads and boundary conditions.A parametrization of the physical domain is provided by employing a set of curvilinear principal *** generalized blendingmethodology accounts for a distortion of the structure so that disparate geometries can be *** layer of the stacking sequence has an arbitrary orientation and is modelled as a generally anisotropic *** addition,re-entrant auxetic three-dimensional honeycomb cells with soft-core behaviour are considered in the *** unknown variables are described employing a generalized displacement field and pre-determined through-the-thickness functions assessed in a unified ***,a weak assessment of the structural problem accounts for shape functions defined with an isogeometric approach starting fromthe computational *** has been proposed to define two-dimensional distributions of static surface *** the same way,boundary conditions with three-dimensional features are implemented along the shell edges employing linear *** fundamental relations are obtained from the stationary configuration of the total potential energy,and they are numerically tackled by employing the Generalized Differential Quadrature(GDQ)method,accounting for nonuniform computational *** the post-processing stage,an equilibrium-based recovery procedure allows the determination of the three-dimensional dispersion of the kinematic and static *** case studies have been presented,and a successful benchmark of different structural responses has been performed with respect to various refined theories.

关键词： 3D honeycomb anisotropic materials differential quadrature method general loads and constraints higher order theories linear static analysis weak formulation

Static Analysis of Anisotropic Doubly-Curved Shell Subjected to Concentrated Loads Employing Higher Order Layer-Wise Theories

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Computer Modeling in Engineering & Sciences 2023年第2期134卷 1393-1468页

作者： Francesco Tornabene Matteo Viscoti rossana Dimitri department of Innovation Engineering School of EngineeringUniversity of SalentoLecce73100Italy

In the presentmanuscript,a Layer-Wise(LW)generalizedmodel is proposed for the linear static analysis of doublycurved shells constrained with general boundary conditions under the influence of concentrated and surface *** unknown field variable is modelled employing polynomials of various orders,each of them defined within each layer of the *** a particular case of the LW model,an Equivalent Single Layer(ESL)formulation is derived *** approaches are outlined for the assessment of external forces,as well as for non-conventional *** doubly-curved shell is composed by superimposed generally anisotropic laminae,each of them characterized by an arbitrary *** fundamental governing equations are derived starting from an orthogonal set of principal ***,generalized blending functions account for the distortion of the physical *** implementation of the fundamental governing equations is performed bymeans of the Generalized Differential Quadrature(GDQ)method,whereas the numerical integrations are computed employing theGeneralized IntegralQuadrature(GIQ)*** the post-processing phase,an effective procedure is adopted for the reconstruction of stress and strain through-the-thickness distributions based on the exact fulfillment of three-dimensional equilibrium equations.A series of systematic investigations are performed in which the static response of structures with various curvatures and lamination schemes,calculated by the present methodology,have been successfully compared to those ones obtained fromrefined finite element three-dimensional *** though the present LW approach accounts for a two-dimensional assessment of the structural problem,it is capable of well predicting the three-dimensional response of structures with different characteristics,taking into account a reduced computational cost and pretending to be a valid alternative to widespread numerical implementations.

关键词： Concentrated load doubly-curved shells generalized differential quadrature laminated anisotropic materials layer-wise theory mapping technique

Vibrio *** Macrobrachium amazonicum prawn farming are inhibited by Moringa oleifera extracts

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Asian Pacific Journal of Tropical Medicine 2015年第11期8卷 899-902页

作者： Raimunda Samia Nogueira Brilhante Jamille Alencar Sales Celia Maria de Souza Sampaio Francisco Geraldo Barbosa Manoel de Araujo Neto Paiva Glaucia Morgana de Melo Guedes Lucas pereira de Alencar Yago Brito de Ponte Tereza de Jesus Pinheiro Gomes Bandeira Jose Luciano Bezerra Moreira debora de Souza Collares Maia Castelo-Branco Waldemiro de Aquino pereira-Neto rossana de Aguiar Cordeiro Jose Julio Costa Sidrim Marcos Fabio Gadelha Rocha department of Pathology and Legal Medicine Postgraduate Program in Medical MicrobiologySpecialized Medical Mycology CenterFederal University of Ceara School of Veterinary Medicine Postgraduate Program in Veterinary SciencesState University of Ceara department of Organic and Inorganic Chemistry Federal University of Ceara

Objective:To investigate the in vitro antimicrobial potential of extracts of stem,leaves,flowers,pods and seeds of Moringu okifera(***) against Vibrio *** hatchery water and the prawn Mmrobrachium ***:The ethanol extracts of stem,leaves,pods and seeds and chloroform extract of flowers of *** were tested against Vibrio cholerue(***) serogroups non-O1/non-O139(n=4).Vibrio vulnificus(n=l) and Vibrio mimicus(n=1).Escherichia coli(***)(ATCC(?) 25922) was used as quality *** species were obtained from Macmbrachium amazonicum prawns and from hatchery water from prawn *** Minimum Inhibitory Concentration(MIC) was determined by broth microdilution ***:The best result was obtained with the ethanol extract of pods,which inhibited three strains of the ***,Vibrio vulnificus,Vibrio minimis and ***(MIC range 0.312-5.000 mg/mL).The chloroform extract of flowers was effective against all *** strains and ***(MIC range 0.625-1.250 mg/mL).However,the ethanol extracts of stem and seeds showed low effectiveness in inhibiting the bacterial ***:The extracts of pods,flowers and leaves of *** have potential for the control of Vibrio *** studies are necessary to isolate the bioaetive compounds responsible for this antimicrobial activity.

关键词： Prawn Macrobrachium amazonicum Moringa oleifera Vi

Chlamydoconidium-producing Trichophyton tonsurans: Atypical morphological features of strains causing tinea capitis in Ceará, Brazil

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Asian Pacific Journal of Tropical Medicine 2019年第8期12卷 380-384页

作者： Raimunda Samia Nogueira Brilhante Germana Costa Paixao Jonathas Sales de Oliveira Vandbergue Santos pereira Marcos Fábio Gadelha Rocha Reginaldo Goncalves de Lima-Neto Débora de Souza Collares Maia Castelo-Branco rossana de Aguiar Cordeiro JoséJúlio Costa Sidrim Specialized Medical Mycology Center Postgraduate Program in Medical MicrobiologyFederal University of CearáRua Nunes de Melo1315FortalezaBrazil Postgraduate Program in Veterinary Sciences State University of CearáAv.Dr.Silas Munguba1700FortalezaBrazil department of Tropical Medicine Center for Health SciencesFederal University of PernambucoRecife-PEBrazil

Objective: To report atypical morphological features of Trichophyton(T.) tonsurans strains associated with tinea capitis. Methods: Eighty-two T. tonsurans strains isolated in Ceará, Brazil, were analyzed regarding macro and micromorphological features and nutritional patterns. Results: Fifty-two samples presented abundant chlamydoconidia, which were produced in chains. Macroscopically, these strains developed small glabrous colonies that were firmly attached to the surface of the culture medium, with few or no aerial mycelia and intense rusty yellow pigmentation. Seven strains did not grow with stimulus from thiamine. Samples were heterogeneous regarding urease production and none presented in vitro hair perforation. Conclusions: The observation of T. tonsurans strains with distinct phenotypic features indicates the need to revise the taxonomic criteria for routine identification of this dermatophyte.

关键词： Trichophyton tonsurans Chlamydoconidia dermatophyte Phenotyping

Bio-mathematical models of viral dynamics to tailor antiviral therapy in chronic viral hepatitis

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World Journal of Gastroenterology 2009年第5期15卷 531-537页

作者： Maurizia rossana Brunetto Piero Colombatto Ferruccio Bonino UO Epatologia Azienda Ospedaliero-Universitaria Pisana 56100 Pisa Italy Direzione Scientifica Fondazione IRCCS Ospedale Maggiore Policlinico Mangiagalli and Regina Elena di Milano 20122 Milano Italy

The simulation of the dynamics of viral infections by mathematical equations has been applied successfully to the study of viral infections during antiviral therapy. Standard models applied to viral hepatitis describe the viral load decline in the f irst 2-4 wk of antiviral therapy, but do not adequately simulate the dynamics of viral infection for the following period. The hypothesis of a constant clearance rate of the infected cells provides an unrealistic estimation of the time necessary to reach the control or the clearance of hepatitis B virus (HBV)/ hepatitis C virus (HCV) infection. To overcome the problem, we have developed a new multiphasic model in which the immune system activity is modulated by a negative feedback caused by the infected cells reduction, and alanine aminotransferase kinetics serve as a surrogate marker of infected-cell clearance. By this approach, we can compute the dynamics of infected cells during the whole treatment course, and find a good correlation between the number of infected cells at the end of therapy and the long-term virological response in patients with chronic hepatitis C. The new model successfully describes the HBV infection dynamics far beyond the third month of antiviral therapy under the assumption that the sum of infected and non-infected cells remains roughly constant during therapy, and both target and infected cells concur in the hepatocyte turnover. In clinical practice, these new models will allow the development of simulators of treatment response that will be used as an "automatic pilot" for tailoring antiviral therapy in chronic hepatitis B as well as chronic hepatitis C patients.

关键词： Viral hepatitis Bio-mathematical models Hepatitis B virus Hepatitis C virus Viral dynamics