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世界核心医学期刊文摘（心脏病学分册） 2006年第7期2卷 2-3页

作者： Pope.cu I. Vaug.an-Sarrazin M.S. rosenthal g. e. 罗亮 De.artme.t of Inte.nal Me.icine University of Iowa Hospitals and Clinics 200 Hawkins Dr SE615-GH Iowa City IA 52240 United States Dr.

Conte.t: Ce.tificate.of ne.d re.0}lations we.e.e.acte. to control he.lth care.costs by limiting.unne.e.sary e.pansion of se.vice.. While.many state. have.re.e.le. ce.tificate.of ne.d re.0}lations in re.e.t ye.rs, fe. analyse. have.e.amine. re.ationships be.we.n ce.tificate.of ne.d re.0}lations and outcome. of care. Obje.tive. To compare.rate. of coronary re.ascularization and mortality afte. acute.myocardial infarction in state. with and without ce.tificate.of ne.d re.0}lations. De.ig., Se.ting. and Participants: Re.rospe.tive.cohort study of 1 139 792 Me.icare.be.e.iciarie. ag.d 68 ye.rs or olde. with AMI who we.e.admitte. to 4587 US hospitals during.2000-2003. Main Outcome.Me.sure.: Thirty-day risk-adjuste. rate. of coronary re.ascularization with e.the. coronary arte.y bypass g.aft surg.ry or pe.cutane.us coronary inte.ve.tion and 30-day all-cause.mortality. Re.ults: The.624 421 patie.ts in state. with ce.tificate.of ne.d re.0}lations we.e.le.s like.y to be.admitte. to hospitals with coronary re.ascularization se.vice.(321 573[51.5%] vs 323 695[62.8%]; Pe.g. re.ascularization at the.admitting.hospital(163 120[26.1%] vs 163 877[31.8%]; Pe.ts in state. without ce.tificate. of ne.d but we.e.more.like.y to unde.g. re.ascularization at a transfe. hospital(73 379[11.7%] vs 45 907[8.9%]; Pg.for de.og.aphic and clinical risk factors, patie.ts in state. with hig.ly and mode.ate.y string.nt ce.tificate.of ne.d re.0}lations, re.pe.tive.y, we.e.le.s like.y to unde.g. re.ascularization within the.first 2 days(adjuste. hazard ratios, 0.68; 95%confide.ce.inte.val[CI], 0.54-0.87; P=.002 and 0.80; 95%CI, 0.71-0.90; Pe.ative.to patie.ts in state. without ce.tificate. of ne.d, althoug. no diffe.e.ce. in the.like.ihood of re.ascularization we.e.obse.ve. during.days 3 throug. 30. Unadjuste. 30-day mortality was similar in state. with and without ce.tificate. of ne.d(109 304[17.5%] vs 90 104[17.5%]; P=.76), as was adjuste. mortalit

关键词：急性心肌梗死证书管理血运重建术血运重建治疗全因死亡率回顾性队列研究临床危险因素冠状动脉

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专科医院和综合医院的心脏血运重建术比较

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世界核心医学期刊文摘（心脏病学分册） 2005年第11期1卷 31-32页

作者： Cram P. rosenthal g. e. Vaug.an-Sarrazin M. S. 张宪伟 De.artme.t of Me.icine Univ. of Iowa College of Medicine 200 Hawkins Drive Iowa City IA 52242 United States Dr.

BACKg.OUND: The.e.e.g.nce.of spe.ialty hospitals focusing.on narrow proce.ural are.s has g.ne.ate. controve.sy, althoug. little.is known about the.r quality. Me.HODS: We.conducte. a re.rospe.tive.cohort study of 42,737 Me.icare.be.e.iciarie. who unde.we.t pe.cutane.us coronary inte.ve.tion(PCI) and 26,274 who unde.we.t coronary-arte.y bypass g.afting.CABg. during.2000 and 2001 in spe.ialty cardiac hospitals(15 for PCI and 15 for CABg. and g.ne.al hospitals(82 for PCI and 75 for CABg. in the.same.marke.s. Administrative.data we.e.use. to compare.patie.ts’characte.istics, hospital proce.ural volume., and patie.t outcome.. Re.ULTS: Patie.ts unde.g.ing.PCI or CABg.in spe.ialty hospitals we.e.le.s like.y to have.coe.isting.conditions than those.be.ng.tre.te. at g.ne.al hospitals and we.e.le.s like.y to have.had an acute.myocardial infarction(Pe.be.te. he.lth of the.patie.ts at spe.ialty hospitals than of those.at g.ne.al hospitals was re.le.te. by the.lowe. me.n pre.icte. risk of de.th(2.1 pe.ce.t vs. 3.1 pe.ce.t for PCI and 5.0 pe.ce.t vs. 5.8 pe.ce.t for CABg. Pe.ch comparison). Me.n volume. of PCI and CABg.proce.ure. in 2000 and 2001 we.e.hig.e. in spe.ialty hospitals than in g.ne.al hospitals(799 vs. 375 PCI proce.ure., Pg.proce.ure., Pe.unadjuste. rate.of de.th during.the.inde. hospitalization or within 30 days afte. admission was lowe. in spe.ialty hospitals than in g.ne.al hospitals(2.1 pe.ce.t vs. 3.2 pe.ce.t for PCI and 4.7 pe.ce.t vs. 6.0 pe.ce.t for CABg. Pe.analyse. adjuste. for patie.ts’characte.istics, the.odds ratio for de.th afte. PCI in spe.ialty hospitals and g.ne.al hospitals was similar(0.89; 95 pe.ce.t confide.ce.inte.val, 0.69 to 1.15; P=0.39), but the.odds ratio for de.th afte. CABg.was lowe. in spe.ialty hospitals than in g.ne.al hospitals(0.84; 95 pe.ce.t confide.ce.inte.val, 0.72 to 0.99; P=0.05). In stratifie. analyse. comparing.spe.ialt

关键词：专科医院综合医院血运重建术急性心肌梗死手术量冠状动脉搭桥术患者健康状况校正死亡率比值比回顾性队列研究

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The.case.of the.missing.appe.dix:a case.re.ort of appe.dice.l intussusce.tion at the.site.of colonic mulle.ianosis

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g.stroe.te.olog. Re.ort 2017年第4期5卷 309-312,I0003页

作者： Fe.e.ico P Quirante.Lisandro M Montorfano Fe.e.ico Se.rot Mary e.Billing.on g.ovanna Da Silva e.anue.e.Lo Me.zo Samue. Szomste.n Raul J rosenthal De.artme.t of Surg.ry Cleveland Clinic FloridaWestonFLUSA

Rig.t lowe. quadrant pain is a symptom with an e.ce.tionally broad diffe.e.tial *** of the.appe.dix is a ve.y uncommon condition with many ***,the.patholog.c finding.of e.topic pre.e.ce.of a mixture.of at le.st two mulle.ian-de.ive. tissue.compone.ts is *** re.ort pre.e.ts the.case.of a 49-ye.r-old woman who pre.e.te. twice.with acute.rig.t lowe. abdominal *** of appe.dice.l inve.sion was made.*** e.amination of the.spe.ime. ide.tifie. e.te.sive.e.dome.riosis,e.dosalping.osis and e.doce.vicosis of the.colon *** intussusce.tion and colonic mulle.ianosis,pre.e.t tog.the.,are.discusse.,and re.omme.dations for the.diag.osis and tre.tme.t of appe.dice.l intussusce.tion are.discusse..

关键词： appe.dix appe.dice.l intussusce.tion mulle.ianosis e.doce.vicosis

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超级心智

超级心智

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作者： (美)诺曼·e. 罗森塔尔(Norman e. rosenthal)

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Hybrid optical parame.rically-oscillating.e.itte. at 1930 nm for volume.ric photoacoustic imag.ng.of wate. conte.t

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e.ig.t 2022年第1期2卷 68-74页

作者： Jiawe. Shi Ming.he.g.Li Huajun Tang.Jiqiang.Kang.Najia Sharmin Amir rosenthal Ke.ne.h K.Y.Wong De.artme.t of e.e.trical and e.e.tronic e.g.ne.ring The University of Hong Kong Pokfulam RoadHong KongChina.2 Department of Electrical EngineeringTechnion–Israel Institute of TechnologyTechnion City32000 HaifaIsrael Advance. Biome.ical Instrume.tation Ce.tre Hong Kong Science ParkShatinNew TerritoriesHong KongChina

Wate. plays a vital role.in biolog.cal me.abolism and it would be.e.se.tial to trace.the.wate. conte.t non-invasive.y,such as le.e.ag.ng.the.vibrational absorption pe.k of the.O-H ***,due.to the.lack of an e.ficie.t lase. source.it was challe.g.ng.to imag. the.wate. conte.t in the.de.p tissue.with micron-le.e. spatial *** addre.s this proble.,we.de.e.op a hig.-powe. hybrid optical parame.rically-oscillating.e.itte.(HOPe.at 1930 nm,at which the.vibrational absorption pe.k of the.O-H bond *** maximum pulse.e.e.g. is ove. 1.74μJ with a pulse.re.e.ition rate.of 50 kHz and a pulse.width of 15 *** e.ploy this lase. source.in the.optical-re.olution photoacoustic microscopy(OR-PAM)syste. to imag. the.wate. conte.t in the.phantom and the.biolog.cal tissue.in *** 1930-nm OR-PAM could map the.wate. conte.t in the.comple. tissue.e.vironme.t at hig. spatial re.olution,de.p pe.e.ration de.th,improve. se.sitivity,and suppre.se. artifact sig.al of the.lipid.

关键词： Fibe. optical parame.ric oscillator Thulium-dope. fibe. lase. Photoacoustic microscopy

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因急性心机梗死入住具备或不具备血运重建能力医院的黑人和白人患者在死亡率和应用血运重建方面的差异

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世界核心医学期刊文摘（心脏病学分册） 2007年第10期3卷 13-14页

作者： Pope.cu I. Vaug.an-Sarrazin M.S. rosenthal g.e. 刘少伟 De.artme.t of Inte.nal Me.icine University of Iowa Hospitals and Clinics200 Hawkins DrSE615-GHIowa CityIA 52240United States Dr.

背景:急性心肌梗死(AMI)后应用冠状动脉血运重建的种族差异,已有大量报道。但是,很少有研究观察因AMI入住具备或不具备血运重建能力医院的患者的医疗模式。目的:比较入住具备或不具备血运重建能力医院的黑人和白人AMI患者的转院。

关键词：血运重建患者黑人死亡率白人

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CAR-T ce.l the.apy in ne.ro-oncolog.: applications and toxicity

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Ne.roimmunolog. and Ne.roinflammation 2018年第10期5卷 15-26页

作者： Akanksha Sharma g.stavo De.Le.n Alyx Porte. Marie.F g.ill Allison rosenthal Christine.e.Brown Kristin Swanson Macie. M Mrug.la De.artme.t of Ne.rolog. Mayo ClinicPhoenixAZ 85054USA Division of He.atolog.-Oncolog. Mayo ClinicPhoenixAZ 85054USA Mathe.atical Ne.ro-Oncolog. Lab Mayo ClinicPhoenixAZ 85054USA De.artme.t of He.atolog. and He.atopoie.ic Ce.l Transplantation T Cell Therapeutics Research LaboratoryCity of Hope Beckman Research InstituteDuarteCA 91010USA.

A ne. e.a for cance. tre.tme.t has be.n ushe.e. in with the.fie.d of cance. immunothe.apy. Afte. initial succe.s with syste.ic malig.ancie., se.e.al of the.e.promising.tre.tme.ts are.be.ng.inve.tig.te. for e.ficacy with primary and se.ondary brain tumors. Chime.ic antig.n re.e.tor (CAR) T ce.ls are.be.ng.studie., both with syste.ic infusion and dire.t administration to the.tumor and into the.ce.e.rospinal fluid, with promising.e.rly re.ults. Syste.ic CAR-T tre.tme.t can have.se.ious syste.ic and ne.rolog.cal toxicitie. that are.important for the.practicing.ne.rolog.st and ne.ro-oncolog.st to know and unde.stand. This re.ie. aims to discuss adoptive.ce.l the.apie. with a focus on CAR-T tre.tme.t. We.re.ie. use.of this the.apy in brain cance.s, particularly malig.ant g.ioma, and provide.an ove.vie. of the.toxicity of CAR-T tre.tme.t and its appropriate.manag.me.t.

关键词： CAR-T ce.l immunothe.apy brain tumor cytokine re.e.se syndrome

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患者和医院差异相关的冠状动脉旁路移植术后结局的种族差异

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世界核心医学期刊文摘（心脏病学分册） 2005年第9期1卷 40-41页

作者： Kone.y S.H. Vaug.an Sarrazin M.S. rosenthal g.e. 张迎捷 Dr.Div. of g.ne.al Inte.nal Me.icine Univ. of Iowa Hospitals and Clinics SE618 GH 200 Hawkins Dr Iowa City IA 52246 United States

Backg.ound -Fe. studie. have.e.amine. the.association of race.and outcome. afte. coronary arte.y bypass g.aft(CABg.surg.ry while.controlling.for both patie.t and hospital e.fe.ts. Me.hods and Re.ults -We.re.rospe.tive.y analyze. data on a cohort of 566 785 white.and 24 354 black Me.icare.be.e.iciarie. 65 ye.rs old and olde. unde.g.ing.CABg.in 1091 US hospitals from 1997 to 2000. Mortality and re.e.t re.ascularization rate. we.e.e.amine. afte. se.ue.tial adjustme.t for patie.t and hospital diffe.e.ce. by use.of g.ne.alize. e.timating.e.uations. Unadjuste. mortality was hig.e.(Pe.patie.ts at 30(6.4%ve.sus 5.2%), 90(8.3%ve.sus 6.6%), and 365 days(13.5%ve.sus 9.8%) afte. surg.ry. Black patie.ts we.e.more.like.y(Pe.g. CABg.at hospitals with the.hig.e.t mortality(56%ve.sus 47%) and at hospitals in the.lowe.t volume.quintile.24%ve.sus 20%). Adjuste. only for patie.t characte.istics, mortality was 8%, 11%, and 25%hig.e. in black patie.ts at 30, 90, and 365 days. Afte. adjustme.t for hospital e.fe.ts, 30 and 90 day mortality was similar but 17%hig.e. in black patie.ts at 365 days. Racial diffe.e.ce. in mortality we.e.g.e.te. in me. than in wome.. On adjustme.t for patie.t and hospital e.fe.ts, re.e.t re.ascularization rate. we.e.similar in black and white.patie.ts. Conclusions -Racial disparitie. in CABg.outcome. are.se.sitive.to the.e.fe.ts of se. and duration of postsurg.cal follow-up. The.incre.sing.disparity in outcome. as follow-up incre.se. is consiste.t with the.hypothe.is that black patie.ts have.le.s acce.s to se.ondary pre.e.tion and re.abilitation se.vice. afte. surg.ry.

关键词：种族差异血运重建广义估计方程校正死亡率二级预防康复治疗持续时间医疗保险

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接受主动脉瓣置换术的黑人和白人老年患者的治疗差异

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世界核心医学期刊文摘(心脏病学分册) 2006年第3期 44-45页

作者： Sche.be.t e.B. rosenthal g.e. We.ke.K.F. Vaug.an-Sarrazin M.S. 马超 De.artme.t of Inte.nal Me.icine University of Iowa Hospitals and Clinics 200 Hawkins Dr Iowa City IA 52242 United States Dr.

Backg.ound-Most prior studie. of racial diffe.e.ce. in the.de.ive.y of cardiac care.have.focuse. on pote.tial diffe.e.ce. in tre.tme.t by individual physicians and hospitals. Howe.e., diffe.e.tial use.of hospitals with variable.practice.patte.ns mig.t also contribute.to variations in care. Me.hods and Re.ults -We.compare. the.use.of bioprosthe.ic valve.(BPVs) in 78 154 black and white.Me.icare.be.e.iciarie. ≥ 65 ye.rs of ag. unde.g.ing.aortic valve.re.lace.e.t in 904 US hospitals during.1999 throug. 2001. g.ne.alize. line.r mixe. mode.s we.e.use. to account first for diffe.e.ce. in patie.t characte.istics and the. for diffe.e.ce. in hospitals use. by black and white.patie.ts. BPV use.was lowe. in black patie.ts re.ative.to white.patie.ts afte. adjustme.t for patie.t characte.istics(re.ative.risk, 0.93; 95% CI, 0.91 to 0.95; Pe.e., black patie.ts we.e.more.like.y to unde.g. surg.ry in hospitals in the.lowe.t quintile.of BPV use.ove.all(29% ve.sus 20% of white.patie.ts; Pe. hospital-le.e. variability in BPV use.was accounte. for, the.use.of BPVs was actually some.hat hig.e. in black patie.ts(re.ative.risk, 1.06; 95% CI, 1.04 to 1.09; Pe. discrimination as me.sure. by the.c statistic was marke.ly hig.e. afte. the.addition of hospital e.fe.ts(0.80 ve.sus 0.59 for patie.t characte.istics alone. Pg.for diffe.e.ce. in hospitals pre.e.e.tially use. by black and white.patie.ts had a major impact on e.timating.racial diffe.e.ce. in the.use.of BPVs in patie.ts unde.g.ing.aortic valve.re.lace.e.t. Hospital-le.e. e.fe.ts e.plaine. a larg.r proportion of the.variation in BPV use.than race.and othe. patie.t characte.istics alone.

关键词：主动脉瓣置换术患者白人黑人差异

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持久单侧眼眶和眼睑水肿为唇舌水肿-面瘫综合征综合征的一种表现

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世界核心医学期刊文摘（皮肤病学分册） 2005年第7期1卷 24-25页

作者： Cocuroccia B. g.bine.li e. Anne.si g. g.g.rolomoni 李晓莉冯义国 Ist. De.mopatico de.l' Immacolata IRCCS Via Monti di Creta 104 00167 Roma Italy

Me.ke.sson-rosenthal syndrome.(MRS) is a comple. ne.romucocutane.us disorde. characte.ize. by localize. orofacial oe.e.a and cranial ne.ve.dysfunction, fre.ue.tly associate. with minor sig.s, including.furrowe. tong.e. Comple.e.forms are.rare.whe.e.a smono-and olig.symptomatic variants are.more.common. A 71-ye.r-old man pre.e.te. with a 2-ye.r history of re.apsing.and prog.e.sive.y pe.siste.t oe.e.a of the.rig.t e.e.ids and pe.iorbital re.1}on. A fissure. tong.e.and te.ang.e.tatic rosace. had be.n pre.e.t since.the.ag. of 50 and 60 ye.rs, re.pe.tive.y. The.patie.t was also affe.te. by e.se.tial hype.te.sion and diabe.e. me.litus. A skin biopsy showe. a marke. uppe. de.mal oe.e.a, and small e.ithe.ioid ce.l g.anulomas arrang.d in pe.ivascular and pe.ilymphatic location. Colle.tions of small e.ithe.ioid ce.ls we.e.occasionally obse.ve. within lymphatic space.. No acid-fast bacte.ia, fung. or fore.g. bodie. we.e.de.e.te.. Intrale.ional corticoste.oids induce. transie.t improve.e.t, whe.e.s minocycline. clofazimine.and dapsone.have.be.n ine.fe.tive. MRS may pre.e.t with unilate.al e.e.id and pe.iorbital swe.ling. Diffe.e.tial diag.ose. of such case. may include.a varie.y of cutane.us, ophthalmic and syste.ic dise.se..

关键词：唇舌水肿眼睑水肿面部水肿沟纹舌皮肤活检氯法齐明二甲胺四环素眶周脑神经功能上皮样细胞

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