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Adverse Effects of Exposure to Fine Particulate Matters and Ozone on Gestational Hypertension

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Current Medical Science 2019年第6期39卷 1019-1028页

作者： rong YANG Dan LUO Yi-ming ZHANG Ke HU Zheng-min QIAN Li-qin HU Long-jiao SHEN Hong XIAN Juliet Iwelunmor Su-rong mei Wuhan Children's Hospital(Wuhan Maternal and Child Healthcare Hospital) Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430015China Key Laboratory of Environment and Health Ministry of Education&Ministry of Environmental Protectionand State Key Laboratory of Environment HealthSchool of Public HealthTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Wuhan Environmental Monitoring Center Wuhan 430015China College for Public Health&Social Justice Saint Louis University^Saint LouisMO 63104USA

Gestational hypertension(GH)is a common complication during *** is regarded as a potential public health challenge for pregnant women and *** evidence has linked ambient air pollution to an increased GH ***,most of the studies were conducted in developed countries,with inconsistent results *** present study was performed to explore whether exposure to particulate matters with an aerodynamic diameter≤2.5(PM2.5)and ozone(O3)was related to elevated odds of GH in a Chinese *** population-based cohort study involved 38115 pregnant women in Wuhan,*** information was collected from the Wuhan Maternal and Child Health Management Information System,using standardized quality *** daily air pollutant data for PM2.5 and O3 were obtained from the 20 monitoring stations of the Wuhan Environmental Monitoring Center during *** nearest monitor approach was applied to individual exposure assessment of PM2.5 and O3 for each *** adjusting for major confounders and other air pollutants,a 10μg/m^3 increase in PM25 and O3 concentrations was found to correlate to a 1.14-fold[95%confidence interval(95%CI):1.09,1.20]and a 1.05-fold(95%CI:1.02,1.07)increase in GH risk,***,stronger relationships between GH risk and PM25 and O3 exposure were observed in women who conceived in winter and summer,*** findings suggest that air pollutants may contribute to the development of GH.

关键词： air pollution fine particulate matter ozone hypertensive disorders of pregnancy gestational hypertension

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Auntie Lan

Women of China 1998年第5期 25-26页

作者： XIAO mei A rong

TIANLIN 13 Village, where I live, sits in the southwest corner of Shanghai. It was built in the early 1980s. Whenever the people of the community have problems, they always turn to the woman in charge of the neighborhood committee for help. Most of the residents do not know her real name. They simply refer to her affectionately as their "Auntie Lan." I met Auntie Lan for the first time when I came to the neighborhood committee office to donate some clothes for the people of an area hit by an earthquake. The bright and tidy office, with its wall covered by all kinds of certificates of merit, impressed me deeply. Auntie Lan took the trouble to carefully count and record the donated money and clothes. Her neat penmanship on the notebooks was in harmony with the orderly office.

关键词： Auntie Lan

Rainfall and Tillage Impacts on Soil Erosion of Sloping Cropland with Subtropical Monsoon Climate- A Case Study in Hilly Purple Soil area, China

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Journal of Mountain Science 2015年第1期12卷 134-144页

作者： TANG Jia-liang CHENG Xun-qiang ZHU Bo GAO mei-rong WANG Tao ZHANG Xi-feng ZHAO Pei YOU Xiang Key Laboratory of Mountain Environment Evolution and Regulation Institute of Mountain Hazards and EnvironmentChinese Academy of Sciences Provincial Monitoring Station of Soil and Water Conservation

Under global warming, storm events tend to intensify, particularly in monsoon-affected regions. As an important agricultural area in China, the purple soil region in the Sichuan Basin, where it has a prevailing monsoon climate, is threatened by serious soil erosion. Tillage operations alter runoff and soil erosion processes on croplands by changing the physical properties of the soil surface. To clarify the relationship between tillage and soil erosion in the purple soil region, three different tillage practices in this region were investigated at the plot scale over 4 years： bare land with minimum tillage （BL）, conventional tillage （CT） and seasonal no-tillage ridges （SNTR） which was initially designed to prevent soil erosion by contoured ridges and no-tillage techniques. The results showed that although there were no significant differences in the surface runoff and soil erosion among the three oractices, BL caused relatively high surface runoff and soil erosion, followed by CT and SNTR. Classification and comparison of the rainfall events based on cluster analysis （CA） verified that the surface runoff was not significantly different between most intensive event and long intensive events but was significantly different between most intensive and short and medium-duration events. Only the rainfall events with the highest rainfall intensity could trigger serious soil erosion, up to 1000 kg ha^-1 in the region. Further detailed investigations on the effects of tillage operations on the soil erosion in a subtropical region with a monsoon climate are needed to provide a basis for modeling catchments and designing better management practices.

关键词： Soil erosion Purple soil Tillage types Rainfall intensity Cluster analysis.

Synthesis, Spectroscopic Properties, and Photodynamic Anticancer Activities of Novel Arginine-modified Silicon(Ⅳ) Phthalocyanines

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Chinese Journal of Structural Chemistry 2020年第1期39卷 66-78,3页

作者： YING Jia-Wen SUN Qun YANG Li-Fang KE mei-rong HUANG Jian-Dong College of Chemistry State Key Laboratory of Photocatalysis on Energy and EnvironmentFujian Provincial Key Laboratory of Cancer Metastasis Chemoprevention and ChemotherapyFuzhou UniversityFuzhou 350116China

We design and synthesize a series of novel silicon(IV)phthalocyanines(SiPcs,1a,2a,1b,and 2b)axially conjugated with arginine or arginine-containing oligopeptides(Arg-Arg,Cys-Arg,Cys-Arg-Arg)through ester or ether linkers to demonstrate the effects of substituents and coupling ways on the spectral behaviors and photodynamic *** ester-linked SiPcs(1a and 2a)show slight red-shift,higher fluorescence emission and singlet oxygen generation compared to the ether-linked analogues(1b and 2b)due to the stronger electron-withdrawing ability of the ester group,suggesting that electronic effect of the linkers plays an important role in their spectral *** introduction of arginine could effectively reduce the aggregation of phthalocyanine in aqueous *** higher cellular uptake and plasma membrane localization ability,1b and 2b exhibit significantly higher photocytotoxicity against both HepG2 and Hela ***,the in vivo fluorescence imaging suggests that 2b is the most specific toward H22 tumor-bearing ICR mice,and it shows efficient tumor growth inhibition with the tumor inhibition rate up to 93%.Thus,this work would provide a new reference for the development of phthalocyanine-based photosensitizers.

关键词： photodynamic therapy phthalocyanine arginine spectral property anticancer activity

Studies on the Protonation and Complexations of Dioxotetraamine Macrocycles

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Chinese Chemical Letters 1996年第9期7卷 864-867页

作者： Wan Dong CHEN Xiang Chen YIN Shou rong ZHUa Hua Kuan LIN Appolin Bave KONDIANO mei rong LIN and Yun Ti CHEN (Department of Chemistry.Nankai University,Tianjin 300071)(Department of Chemistry,Jining Teacher’s College,Jining 272125)(Institute of Modern Op NANKAI UNIV DEPT CHEMTIANJIN 300071PEOPLES R CHINA JINING TEACHERS COLL DEPT CHEMJINING 272125PEOPLES R CHINA NANKAI UNIV INST MODERN OPTTIANJIN 300071PEOPLES R CHINA

14-Membered macrocyclic dioxotetraamines deprotonate stepwisely upon coordination to cupric ions. Singly- and doubly-deprotonated complexes are the main species, While for 13-membered analogs, non- and doubly-deproton... 详细信息

关键词： Studies on the Protonation and Complexations of Dioxotetraamine Macrocycles

Goos-Hanchen-like shift related to spin and valley polarization in ferromagnetic silicene

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Chinese Physics B 2021年第10期30卷 523-529页

作者： mei-rong Liu Zheng-Fang Liu Ruo-Long Zhang Xian-Bo Xiao Qing-Ping Wu Department of Applied Physics East China Jiaotong UniversityNanchang 330013China School of Computer Science Jiangxi University of Traditional Chinese MedicineNanchang 330004China

We study the Goos-Hanchen-like shift of single silicene barrier under the external perpendicular electric field,off- resonant circularly polarized light and the exchange field modulation using the stationary-phase *** results show that the Goos-Hanchen-like shift of silicene resulting from the external perpendicular electric field does not have the characteristics of spin or valley polarization,while that from off-resonant circularly polarized light or the exchange field is *** importantly,the combined effect of the external perpendicular electric field and the exchange field or off-resonant circularly polarized light can cause the Goos-Hanchen-like shift of the system to be spin and valley *** is particularly worth noting that when the three modulations are considered at the same time,as the exchange field changes,the system will have a positive or negative Goos-Hanchen-like shift.

关键词： Goos-Hanchen-like shift silicene polarization

Leonurine: From Gynecologic Medicine to Pleiotropic Agent

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Chinese Journal of Integrative Medicine 2020年第2期26卷 152-160页

作者： LI Yun-yun LIN Yi-kong LIU Xin-hua WANG Li YU Min LI Da-jin ZHU Yi-zhun DU mei-rong NHC Key Lab of Reproduction Regulation(Shanghai Institute of Planned Parenthood Research) Hospital of Obstetrics and Gyn ecologyFuda n Un iversity Sha nghai Medical CollegeShanghai(200011)China Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases Shanghai(200011)China Shanghai Key Laboratory of Bioactive Small Molecules Department of PharmacologySchool of PharmacyFudan UniversityShanghai(201203)China State Key Laboratory of Quality Research in Chinese Medicine and School of Pharmacy Macao Un iversity of Science and Tech no logyMacao SARChina

Leonurus japonicus Houtt,a Chinese traditional herbal medicine,has been widely used to cure gynecological diseases,such as incomplete abortion and ***,a major active alkaloid compound only be found in Leonurus japonicus Houtt,has been successfully extracted and *** evidence has shown that leonurine can regulate a variety of pathologic processes including oxidative stress,inflammation,fibrosis,apoptosis,and multiple metabolic ***,we have reviewed the pharmacological actions and biological functions of leonurine,with a focus on the role of leonurine in the amelioration of various pathological *** into the related signaling pathways and molecular mechanisms have strengthened our understanding on the function of leonurine in the alleviation of multiple pathological *** summary of the existing researches should help direct future research into the basic science and clinical applications in related diseases.

关键词： leonurine Leonurus japonicus Houtt Chinese medicine oxidative stress inflammation fibrosis clinical application

Validity and reliability testing of the Chinese (mainland) version of the 39-item Parkinson's Disease Questionnaire (PDQ-39)

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2010年第7期11卷 531-538页

作者： Wei LUO Xiao-hong GUI Bo WANG Wen-ying ZHANG Zhi-yuan OUYANG Yi GUO Bao-rong ZHANG mei-ping DING Department of Neurology the Second Affiliated Hospital School of Medicine Zhejiang University Hangzhou 310009 China

The 39-item Parkinson's Disease Questionnaire (PDQ-39) has been tested in many languages, but not in Chinese mainland. We aimed to assess the Chinese (mainland) version of the PDQ-39. Seventy-one subjects with Parkinson's disease (PD) completed the PDQ-39 and the Medical Outcomes Study 36-item Short Form Health Survey (SF-36). All subjects were retested with the PDQ-39 a week later. The united Parkinson's disease rating scale (UPDRS) and the Hoehn and Yahr (H & Y) scale were also used to evaluate the subjects. Reliability was assessed by Cron- bach's α and intra-class correlation coefficient (ICC). Validity was examined in terms of agreement with SF-36, UPDRS, and H & Y scales. The Chinese (mainland) version of the PDQ-39 demonstrated acceptable reliability (Cronbach's α: 0.84-0.88; ICC: 0.56-0.82). The item-total correlations (0.33-0.88) and scaling success rates (77.56%) indicated satisfactory convergent and discriminant validity of the PDQ-39 items. The correlations between related constructs of the PDQ-39 and UPDRS (r=0.44-0.68) and between those of the PDQ-39 and SF-36 (r=(-0.46)-(-0.69)) were all statistically significant (P<0.01). Except for stigma, cognitions, and bodily discomfort, all other dimensions of the PDQ-39 significantly discriminated patients at different H & Y stages indicated by the H & Y scale. Although our observations indicate that some problematic subscales of this version of the PDQ-39 could be improved upon, this study suggests acceptable reliability and validity of the Chinese (mainland) version of the PDQ-39.

关键词： 39-item Parkinson’s Disease Questionnaire (PDQ-39) Quality of life Validity Reliability

Structure prediction, electronic, and mechanical properties of alkali metal MB_(12)(=Be, Mg, Ca, Sr) from first principles

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Chinese Physics B 2021年第1期30卷 464-470页

作者： Chun-Ying Pu rong-mei Yu Ting Wang Zhen-Yan Xüe Yong-Sheng Zhu Da-Wei Zhou College of Physics and Electronic Engineering Nanyang Normal UniversityNanyang 473061China Department of Mathematics and Statistics Nanyang Normal UniversityNanyang 473061China

Using the particle swarm optimization algorithm on structural search methods, we focus our crystal structures search on boron-rich alkali metal compounds of MB_(12)(M = Be, Mg, Ca, Sr) with simulation cell sizes of 1–2 formula units(f.u.)at 0 GPa. The structure, electronic, and mechanical properties of MB_(12) are obtained from the density functional theory using the plane-wave pseudopotential method within the generalized gradient approximations. The formation enthalpies of MB_(12) regarding to solid metal M and solid alpha-boron suggested the predicted structures can be synthesized except for BeB12. The calculated band structures show MB_(12)(M = Be, Mg, Ca, Sr) are all indirect semiconductors. All the calculated elastic constants of MB_(12) satisfy the the mechanical stable conditions. The mechanical parameters(i.e., bulk modulus,shear modulus, and Young’s modulus) are derived using the Voigt–Reuss–Hill method. The G/B ratios indicated that the MB_(12) should exhibit brittle behavior. In addition, the hardness, Debye temperature, universal anisotropic index, and the percentage of anisotropy in compression and shear are also discussed in detail. We hope our results can inspire further experimental study on these boron-rich alkali-metal compounds.

关键词： first-principles calculations structure searching mechanical properties boron-rich alkali-metal compounds