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Dsteosynthesis with long volar locking plates for meta- physeal-diaphyseal fractures of the distal radius

Chinese Journal of Traumatology 2013年第6期16卷 339-343页

作者： Paritosh Gogna Harpal singh Selhi rohit Singla Mukul Mohindra Amit Batra Reetadyuti Mukhopadhyay Rajesh Rohilla Umesh Yadav Department of Orthopaedics and Rehabilitation Pt BDSharma Postgraduate Institute of Medical SciencesRohtak Haryana India Department of Orthopaedics Dayanand Medical Col-lege and Hospital Ludhiana Punjab India

Objective：Metaphyseal-diaphyseal fractures of the distal radius are a major treatment dilemma and orthopaedic surgeons have to pay due consideration to restoration of anatomy of distal radius together with rotation of the radial shaft and maintenance of radial bow and interosseous *** performed this study to evaluate the clinic-radiological outcome of metaphyseal-diaphyseal fractures of the distal radius treated with long volar locking ***：This prospective study involved 27 patients （22 males and 5 females） with metaphyseal-diaphyseal fracture of the distal *** mean age was （30.12±11.48） years （range 19-52 years） and the follow-up was 26.8 months （range 22-34 months）.All patients underwent open reduction and internal fixation with a long volar locking *** to AO/OTA classification,there were 7 type A3,13 type C2 and 7 type C3 *** assessment was done based on the disabilities of the arm,shoulder and hand （DASH） *** evaluation was done by measuring grip strength and range of motion around the wrist and the radiological determinants included radial angle,radial length,volar angle and ulnar *** final assessment was done according to Gartland and Werley scoring ***：Postoperative radiological parameters were well maintained throughout the trial,and there was significant improvement in the functional parameters from 6 weeks to final *** average DASH scores improved from 37.5 at 6 weeks to 4.2 at final *** assessment using Gartland and Werley scoring system revealed 66.67%（n=l8） excellent and 33.33% （n=9） good *** was one case of superficial infection which responded to antibiotics and another carpel tunnel syndrome which was managed ***：Volar locking plate fixation for metaphyseal-diaphyseal fractures of distal radius is associated with excellent to good functional outcome,early rehabilitation and minimal complications.

关键词： Radius fractures Fracture fixation,internal Bone plates

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Missed ulnar nerve injury and closed forearm fracture in a child

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Chinese Journal of Traumatology 2013年第4期16卷 246-248页

作者： Batra Amit Devgan Ashish Verma Vinit singh Raj Batra Shivan Magu Narender Singla rohit Gogna ParitoshGupta Navdeep Department of Orthopedics PGIMS Rohtak HaryanaIndia

Ulnar nerve injury in closed fracture of lbrearnl in children is uncommon. Commonly, neurapraxia is the reason for this palsy but other severe injuries or nerve entrapment has been reported in some cases. The impor- tance of diagnosis concerning the types of the nerve injury lies in the fact that they have totally different management. We present a case of ulnar nerve deficit in a child following a closed fracture of the forearm bones. It is imperative to diagnose exact cause of palsy as it forms the basis for treatment. MR1 scan can help diagnosis and accordingly guide the management. Simple nelwe contusion should be treated conservatively, and exploration with fixation of the fracture should be done in lacerations and entrapments of the nerve. Surgery is not the treatment of choice in cases that could be managed conserwltively.

关键词： Ulnar nerve Peripheral nerve injuries Forearm injuries Child

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Dynamism of Antimicrobial Activity of Actinomycetes—A Case Study from Undisturbed Microbial Niche

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Advances in Microbiology 2014年第6期4卷 324-334页

作者： Jayshree D. Patel Mahesh Parmar Purshottam Patel Pravin rohit Ramesh Taviyad Parveen Ansari Bipasha Bhattacharya Dhaval Vyas Vipin Kumar Nirmal S. Sahay Pawan K. singh National Innovation Foundation India Satellite Complex Nr. Mansi Circle Ahmedabad Gujarat India Sadbhav SRISTI Sanshodhan Laboratory AES Boys Hostel Campus Nr. Gujarat University Library & SBI Bank Navrangpura Ahmedabad Gujarat India

Escalation of drug resistant microbes (bacteria) had forced researchers to search new and improved therapeutic compounds from different possible sources, including metabolites secreted by the actinomycetes. The aim of this study was to evaluate the pattern of antimicrobial actinomycetes from physiologically distinct soil of different geographical locations. Forty five soil samples were collected from 5 districts of Gujarat including two sanctuaries as source of survey for bioactive actinomycetes. Crowded plate technique was used for isolation and Agar cylinder method was employed for the antimicrobial screening. A total of 171 actinomycetes were isolated and screened against eighteen pathogens responsible for causing diseases in plants and humans. Results indicate that 79% of the isolates were active against at least one of the eighteen tested pathogens. Some of the actinomycetes strain had shown strong antibacterial and antifungal activity which may be a good source of obtaining novel antimicrobials.

关键词： Actinomycetes Screening Antimicrobial Drug Resistance Soil Microflora

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评估口服西地那非治疗严重肺动脉高压有效性的一项随机、安慰剂对照、双盲、交叉研究

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世界核心医学期刊文摘（心脏病学分册） 2006年第9期2卷 15-16页

作者： singh T.P. rohit M. Grover A. 杨海涛 Department of Cardiology Post Graduate Institute of Medical Education and ResearchChandigarhIndia.Dr

Background: Severe pulmonary artery hypertension(PAH) is a disorder with limited treatment options. Recently, several newer drugs have recently been introduced to treat PAH. Sildenafil is one which has shown promise in several uncontrolled studies, but controlled trials have been few. In this randomized placebo-controlled study, we evaluated the efficacy of oral sildenafil in idiopathic PAH and PAH caused by Eisenmenger syndrome. Methods: This was a randomized, double-blind, placebo-controlled crossover study. Twenty patients, 10 of each of idiopathic PAH and Eisenmenger syndrome, were randomized to receive placebo or sildenafil in a double-blind manner for 6 weeks and, after a washout period of 2 weeks, were crossed over. The primary end point of efficacy was the improvement in distance covered in 6-minute walk test. Secondary end points were reduction in pulmonary artery pressure as measured by Doppler echocardiography after 6 weeks of treatment, improvement in clinical condition, New York Heart Association(NYHA) class, and exercise duration and metabolic equivalents(Mets) achieved on modified Bruce exercise protocol. Results: There was significant improvement in primary and secondary end points. The primary end point of distance covered in 6-minute walk test improved from 262±99 to 358.9±96.5 m(P< .0001) after treatment with sildenafil. Pulmonary artery pressure, the secondary end point, improved from the baseline of 98.8±20.5 to 78.3±15.3 mm Hg(P< .0001), NYHA class improved from 2.65±0.59 to 1.55±0.51(P< .0001), exercise duration from 6.4±3.1 to 10.2±2.05 minutes(P< .0001), and Mets achieved from 3.32±1.57 to 6.04±1.87(P< .0001) after treatment with sildenafil. There was no significant fall in blood pressure with placebo and sildenafil, and no serious side effects of drug were observed in the study. Conclusions: Sildenafil significantly improved the symptomatic status, exercise capacity, NYHA class, and hemodynamic parameters of patients with severe PAH and can

关键词：安慰剂对照西地那非治疗方法肺动脉高压随机双盲有效性随机化口服

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TiO<sub>2</sub>-Polysulfone Beads for Use in Photo Oxidation of Rhodamine B

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Soft Nanoscience Letters 2012年第4期2卷 67-70页

作者： Sanjay V. Ingale Pratap B. Wagh Arvind K. Tripathi rohit Srivastav Srivastav Imejinary K. singh Ramesh C. Bindal Satish C. Gupta Applied Physics Division Bhabha Atomic Research Centre Mumbai India Chemistry Division Bhabha Atomic Research Centre Mumbai India Desalination Division Bhabha Atomic Research Centre Mumbai India

The nano sized TiO2 has been synthesized by sol gel process. The titaniumisopropaxide diluted in propanol hydrolyzed under acidic condition to form a gel. The solvent from gel pores has been extracted at ambient pressure resulting in nano sized TiO2 crystallites. The crystalline phase of TiO2 could be assigned to anatase structure. An average crystallite size is about 12 nm. The surface area of TiO2 found to be 235 m2/g. The TiO2 nanocrystallites thus produced were blended with polysulphone to form its beads for ease of operation. These beads of TiO2 were used as photo catalyst in conjunction with H2O2 oxidizer in presence of UV light (254 nm) for treating the 50 ppm Rhodamine B aqueous solution. The solution decolorized within 10 minutes resulting in disappearance of absorption peak at around 600 nm in UV spectrometry. The organic entities degrade in about 60 minutes. The beads of nano sized TiO2 could be easily recovered from the treated effluent for further use.

关键词： Photo Oxidation Rhodamine B TiO2 Beads Polysulphone Nanocrystallite

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印度拉达克羌塘地区黑颈鹤日间行为时间分配

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Zoological Research 2014年第S1期35卷 158-166页

作者： Afifullah Khan Pankaj Chandan Jigmet Takpa Syed A.Hussain rohit Rattan Pushpinder singh Jamwal Tanveer Ahmad Aligarh Muslim University AligarhIndia WWF-India 172-BLodi EstateNew DelhiIndia Department of Wildlife Protection LadakhJ&K GovernmentIndia Wildlife Institute of India DehradunGovernment of IndiaIndia

时间分配研究是理解栖息地利用模式、资源利用和限制物种生存因素的合适手段,这些一旦掌握清楚了便可被整合到管理策略的制定中。于2008年、2009年和2010年繁殖期对拉达克地区的黑颈鹤(Grus nigricollis)日间行为时间分配进行了研究。... 详细信息

时间分配研究是理解栖息地利用模式、资源利用和限制物种生存因素的合适手段,这些一旦掌握清楚了便可被整合到管理策略的制定中。于2008年、2009年和2010年繁殖期对拉达克地区的黑颈鹤(Grus nigricollis)日间行为时间分配进行了研究。为了更好地统一繁殖周期内不同繁殖阶段的活动模式,将黑颈鹤的繁殖期分成繁殖前期、繁殖中期和繁殖后期。调查期间,共进行了95天野外调查,黑颈鹤观察时长达785 h,所有观察在06:00—19:00完成,共记录到16314次行为事件。该文中黑颈鹤的日间行为时间分配以不同行为的百分比来表示。繁殖期内,黑颈鹤的取食行为占(48.5±1.3)%,其次分别为休息[(14.2±1.2)%]、运动[(10±0.7)%]、繁殖[(10±2.6)%]、保养[(5.7±0.5)%]、警戒[(4.1±0.9)%]、保卫[(1.5±0.3)%]和求偶炫耀[(0.7±0.2)%],另有(5.4±1.9)%]的时间黑颈鹤飞出观察视野。相较于其他生境,黑颈鹤在沼泽草甸生境中停留的时间最长[(43±0.9)%]。

关键词：拉达克羌塘黑颈鹤时间分配繁殖期

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口服西地那非疗法治疗严重肺动脉高压的效果研究

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中国处方药 2006年第8期5卷 29-29页

作者： singh TP rohit M Grover A 菅鑫妍

背景:严重肺动脉高压(PAH)的治疗手段非常有限。最近有几种新药被引进PAH的治疗。西地那非(sildenafil)在几项无对照的试验中都显示出在此治疗领域有很好的应用前景,但是很少有关于该药的对照试验。在此项随机、安慰剂对照的研究中,我... 详细信息

背景:严重肺动脉高压(PAH)的治疗手段非常有限。最近有几种新药被引进PAH的治疗。西地那非(sildenafil)在几项无对照的试验中都显示出在此治疗领域有很好的应用前景,但是很少有关于该药的对照试验。在此项随机、安慰剂对照的研究中,我们对口服西地那非疗法对特发性PAH以及由艾森曼格综合征(Eisenmenger syndrome)所引起的P、H治疗方面的有效性进行了研究。[第一段]

关键词：肺动脉高压治疗手段西地那非疗法口服 syndrome) 艾森曼格综合征对照试验安慰剂对照 PAH

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关于草药标准化的研究综述(英文)

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中西医结合学报 2012年第10期10卷 1077-1083页

作者： Vandana Garg Vir Ji Dhar Anupam Sharma rohit Dutt Department of Pharmaceutical Sciences Maharshi Dayanand UniversityRohtak 124001 Haryana India Swift School of Pharmacy Village Ghaggar Sarai Tehsil RajpuraPunjab 140401 India University Institute of Pharmaceutical Sciences Panjab UniversityChandigarh 160014 India Guru Gobind singh College of Pharmacy Yamunanagar 135003 Haryana India

由于自然产品有化学多样性的特点,使之具有很高的实用性,无论是作为纯天然化合物或是标准化植物提取物,它们都为新药的开发提供了很多可能。与现代西药比较,草药通常被用于治疗慢性疾病。规范化操作可保证植物的一个或多个活性成分及化... 详细信息

由于自然产品有化学多样性的特点,使之具有很高的实用性,无论是作为纯天然化合物或是标准化植物提取物,它们都为新药的开发提供了很多可能。与现代西药比较,草药通常被用于治疗慢性疾病。规范化操作可保证植物的一个或多个活性成分及化合物的含量。在新药研发方面,植物药的开发成本较低且资源丰富,但植物的生长环境和基因等因素会在很大程度上影响植物提取物的生物化学成分。植物药的生产要求源植物在基因方面的单种栽培完全符合标准条件,以保证其生物化学指标的一致性,并可以优化植物药的安全性和有效性。本文旨在讨论如何改进植物药提取的规范化操作方法以及如何有效制备质量及效果稳定的植物药。

关键词：地道药材植物药植物提取物综述

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印度黑颈鹤现状与分布

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Zoological Research 2014年第S1期35卷 39-50页

作者： Pankaj Chandan Afifullah Khan Jigmet Takpa Syed A.Hussain Kamal Mehdi Pushpinder singh Jamwal rohit Rattan Nisa Khatoon Tsewang Rigzin Anupam Anand Pijush Kr.Dutta Tanveer Ahmad Partha S.Ghose Priyadarshinee Shrestha Lak Tsheden Theengh WWF-India 172-BLodi EstateNew DelhiIndia Aligarh Muslim University AligarhIndia Department of Wildlife Protection Ladakh J&KGovernmentIndia Wildlife Institute of India DehradunGovernment of IndiaIndia University of Maryland USA Tata Institute of Social Sciences Guwahati CampusIndia

为了弄清和监测印度黑颈鹤(Grus nigricollis)的现状与分布,作者于2000-2014年开展了长期研究。每年在所有已知的黑颈鹤分布点开展调查,同时探索了新的区域。基于黑颈鹤的历史分布区,包括查谟和克什米尔、锡金等的文献记载和调查,该文... 详细信息

为了弄清和监测印度黑颈鹤(Grus nigricollis)的现状与分布,作者于2000-2014年开展了长期研究。每年在所有已知的黑颈鹤分布点开展调查,同时探索了新的区域。基于黑颈鹤的历史分布区,包括查谟和克什米尔、锡金等的文献记载和调查,该文对印度黑颈鹤的现状与分布进行了综述,详细列出了黑颈鹤在印度的当前现状与分布。首次对过去15年来印度黑颈鹤种群状况进行了报道:整个研究期间,于2012年在拉达克的繁殖地最多记录到139只黑颈鹤个体,于2006年在印度东北部记录到11个越冬个体。

关键词：黑颈鹤高海拔湿地拉达克锡金

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