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Quantification of displacement and particle crushing around a penetrometer tip

Geoscience Frontiers 2020年第2期11卷 389-399页

作者： Eshan Ganju Fei Han Monica Prezzi rodrigo salgado Juliana Spohr Pereira Lyles School of Civil Engineering Purdue University

Particle crushing occurs near the tip of a penetrometer and influences the development of the tip *** study particle crushing near a penetrometer tip,a cone penetrometer was monotonically jacked and then load-tested in medium dense and dense silica sand samples prepared in a halfcylindrical calibration chamber with viewing *** the tests,images of the advancing penetrometer and the surrounding soil were taken using digital cameras and analyzed to obtain the displacement and strain fields around the penetrometer using the Digital Image Correlation(DIC)***,soil samples were collected near the tip of the penetrometer using a novel agarimpregnation technique and digitized using an X-ray *** digitized samples were analyzed to reconstruct the three-dimensional models of individual particles,generating the gradation and relative breakage parameters of the sand around the cone penetrometer.

关键词： Crushing DIC Penetrometer X-ray CT

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Timely reperfusion for ST-segment elevation myocardial infarction:Effect of direct transfer to primary angioplasty on time delays and clinical outcomes

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World Journal of Cardiology 2014年第6期6卷 424-433页

作者： rodrigo Estévez-Loureiro ángela López-Sainz Armo Pérez de Prado Carlos Cuellas Ramón Calvio Santos Norberto Alonso-Orcajo Jorge salgado Fernández Jose Manuel Vázquez-Rodríguez Maria López-Benito Felipe Fernández-Vázquez Division of Cardiology Complejo Asistencial Universitario de León (CAULE)24071 LeonSpain Division of Cardiology Complejo Hospitalario Universitario A Coru?a (CHUAC)15006 La Coru?aSpain

Primary percutaneous coronary intervention(PPCI) is the preferred reperfusion therapy for patients presenting with ST-segment elevation myocardial infarction(STEMI) when it can be performed expeditiously and by experienced operators. In spite of excellent clinical results this technique is associated with longer delays than thrombolysis and this fact may nullify the benefit of selecting this therapeutic option. Several strategies have been proposed to decrease the temporal delays to deliver PPCI. Among them,prehospital diagnosis and direct transfer to the cath lab,by-passing the emergency department of hospitals,has emerged as anattractive way of diminishing delays. The purpose of this review is to address the effect of direct transfer on time delays and clinical events of patients with STEMI treated by PPCI.

关键词： Primary angioplasty Direct transfer STsegment elevation myocardial infarction network Primary percutaneous coronary intervention Myocardial infarction

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Bone Remodeling, Biomaterials And Technological Applications: Revisiting Basic Concepts

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Journal of Biomaterials and Nanobiotechnology 2011年第3期2卷 318-328页

作者： Patricia C.salgado Plinio C.Sathler Helena C.Castro Gutemberg G.Alves Aline M.de Oliveira rodrigo Cde Oliveira Monica D.C.Maia Carlos R.Rodrigues Paulo G.Coelho Andre Fuly Lúcio M.Cabral Jose M.Granjeiro Program of Post-Graduation in Medical Sciences Fluminense Federal UniversityNiteróiBrazil Post-Graduation in Biology of Interactions Institute of BiologyFluminense Federal UniversityNiteróiBrazil Program of Post-Graduation in Pathology Fluminense Federal UniversityNiteróiBrazil Clinical Research Unit Antonio Pedro HospitalNucleus of Cell TherapyFluminense Federal UniversityNiteróiBrazil School of Odontology Fluminense Federal UniversityNiteróiBrazil Department of Biological Sciences Dental School of BauruSão Paulo UniversitySão PauloBrazil School of Pharmacy Federal University of Rio de JaneiroRio de JaneiroBrazil Department of Biomaterials and Biomimetics New York UniversityNew YorkUSA

Presently, several different graft materials are employed in regenerative or corrective bone surgery. However current misconceptions about these biomaterials, their use and risks may compromise their correct application and development. To unveil these misconceptions, this work briefly reviewed concepts about bone remodeling, grafts classification and manufacturing processes, with a special focus on calcium phosphate materials as an example of a current employed biomaterial. Thus a search on the last decade was performed in Medline, LILACS, Scielo and other scientific electronic libraries using as keywords biomaterials, bone remodeling, regeneration, biocompatible materials, hydroxyapatite and therapeutic risks. Our search showed not only an accelerated biotechnological development that brought significant advances to biomaterials use on bone remodeling treatments but also several therapeutic risks that should not be ignored. The biomaterials specificity and limitations to clinical application point to the current need for developing safer products with better interactions with the biological microenvironments.

关键词： Biocompatible materials Bone remodeling Hydroxyapatite Therapeutic risks

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Physical Activity Alters Superoxide Dismutase Activity and Intercellular Adhesion Molecule 1 Levels in Diabetes Mellitus Type 2 Patients

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Journal of Biosciences and Medicines 2023年第7期11卷 140-150页

作者： Anderson Martins Tavares Leonardo Matta Jaslana Hainfellner da Silva Christiane de Oliveira Bensusan Carla do Nascimento Giselle Fernandes Taboada rodrigo Soares Fortunato Luciene de Carvalho Cardoso-Weide Postgraduate Program in Medical Sciences School of Medicine UFF-Universidade Federal Fluminense Rio de Janeiro Brazil Carlos Chagas Filho Institute of Biophysics UFRJ-Federal University of Rio de Janeiro Rio de Janeiro Brazil School of Biology University Salgado de Oliveira Rio de Janeiro Brazil Endocrinology Unit Department of Internal Medicine School of Medicine UFF-Universidade Federal Fluminense Rio de Janeiro Brazil Medical School Department of Pathology UFF-Universidade Federal Fluminense Rio de Janeiro Brazil Luciene de Carvalho Cardoso Weide Medical School Department of Pathology UFF-Universidade Federal Fluminense Rio de Janeiro Brazil

Background: Oxidative stress and inflammation are related to the pathophysiology of diabetes mellitus (DM), being involved in the development of micro-and macrovascular complications. Physical activity is beneficial for DM patients, but little is known about the relationship between redox and inflammation biomarkers and the level of physical activity in these patients. Based on this, this research aims to evaluate the effects of physical activity level on redox stress parameters and inflammatory markers in T2DM patients. Methods: Eighty-four patients with T2DM were divided according to their physical activity level: group A (n = 48), sedentary;group B (n = 11) active (3 times a week, 150 min) and group C (n = 25), highly active (5 times a week, 150 - 300 mins, at least). Anthropometric and biochemical parameters, superoxide dismutase (SOD) and glutathione peroxidase (GPx) activities, as well as GSH, sRAGE and ICAM-1 levels were assessed. Results: Glycated haemoglobin, total cholesterol, and LDL-cholesterol levels were lower in the highly active group in comparison to other groups. Plasma SOD activity was higher in group C compared to Group A, while ICAM-1 levels were significantly higher in group B when compared to other groups. Conclusion: Our results suggest that the practice of physical activity is beneficial to T2DM patients, especially at high volume and frequency.

关键词： Cardiovascular Risk Exercise Health Inflammation Oxidative Stress

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Bone Remodeling, Biomaterials and Technological Applications: Revisiting Basic Concepts

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Journal of Biomaterials and Nanobiotechnology（生物材料与纳米技术） 2011年第3期

作者： Patrícia C. salgado Plínio C. Sathler Helena C. Castro Gutemberg G. Alves Aline M. de Oliveira rodrigo C. de Oliveira Mônica D. C. Maia Carlos R. Rodrigues Paulo G. Coelho Andre Fuly Lúcio M. Cabral Jose M. Granjeiro

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