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Maintenance of demographic and hematological profiles in a long-lasting dengue fever outbreak: implications for management

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Infectious Diseases of Poverty 2016年第1期5卷 776-786页

作者： Andréia Moreira dos sa.tos Carmo rodrigo Buzinaro Suzuki Michele Marcondes Riquena André Eterovic árcia Aparecida Sperança Center for Natural and Human Sciences Universidade Federal do ABCCampus São Bernardo do Campo09606-070 São Bernardo Do CampoSão PauloBrasil Secretaria do Estado da saúde do Estado de São Paulo Instituto Adolfo LutzCentro de Laboratório Regional VIIISanto André09040-160São PauloBrazil Discipline of Parasitology Marilia Medical SchoolMarilia 17519-030São PauloBrazil Center for Natural and Human Sciences Universidade Federal do ABCCampus Santo AndréSanto André09210-170São PauloBrazil

Background:Dengue fever(DF)outbreaks present regionally specific epidemiological and clinical *** certain medium-sized cities(100000–250000 inhabitants)of São Paulo State,Brazil,and after reaching an incidence of 150 cases/100000 inhabitants(“epidemiological threshold”),clinical diagnosis indicated dengue virus(DENV)*** this period,other seasonally infectious diseases with symptoms and physical signs mimicking DF can simultaneously occur,with the consequential overcrowding of health care facilities as the principal *** of clinical diagnosis of DF with serological tests may help in avoiding faulty diagnosis in patients,who might later undergo dengue hemorrhagic fever(DHF)and the dengue-shock syndrome(DSS).Furthermore,demographic and hematological profiles of patients are useful in detecting specific early characteristics associated to DF,DHF and ***:From March to June,2007,456 patients from Marilia in northwest São Paulo State who had only been diagnosed for DF by clinical criteria,underwent serologic testing for non-structural 1(NS1)DENV *** results were used in comparative analysis according to demographic(gender,age)and hematological(leukocyte and platelet counts,percentage of atypical lymphocytes)*** patterns were evaluated by subdividing data according to time of initial attendance,using recorded variables as predictors of DENV infection in logistic regression models and ROC ***:Serologic DENV detection was positive in 70.6%of the *** leukocyte and platelet counts were the most important factors in predicting DENV infection(respective medians DENV+=3715 cells/ml and DENV-=6760 cells/ml,and DENV+=134896 cells/ml and DENV-=223872 cells/ml).Furthermore,all demographic and hematological profiles presented a conservative temporal pattern throughout this long-lasting ***:As consistency throughout the epidemic facilitated defining the conservation

关键词： Clinical diagnosis Demographic profile Dengue fever Dengue-outbreak pattern Epidemiological threshold Hematological profile

The effects of plyometric jump training on lower-limb stiffness in healthy individuals:A meta-analytical comparison

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Journal of Sport and Health Science 2023年第2期12卷 236-245页

作者： Jason Moran Bernard Liew rodrigo Ramirez-Campillo Urs Granacher Yassine Negra Helmi Chaabene School of Sport Rehabilitation and Exercise SciencesUniversity of EssexColchesterEssex CO43SQUK Department of Physical Activity Sciences Universidad de Los LagosOsorno 5290000Chile Division of Training and Movement Science University of PotsdamPotsdam 14469Germany Higher Institute of Sport and Physical Education of Ksar saı¨d University of Manouba Tunis 2037Tunisia High Institute of Sports and Physical Education of Kef University of JendoubaJendouba 8189Tunisia

Purpose:This study aimed to examine the effects of plyometric jump training(PJT)on lower-limb ***:Systematic searches were conducted in PubMed,Web of Science,and *** participants included healthy males and females who undertook a PJT programme isolated from any other training ***:There was a small effect size(ES)of PJT on lower-limb stiffness(ES=0.33,95%confidence interval(95%CI):0.07-0.60,z=2.47,p=0.01).Untrained individuals exhibited a larger ES(ES=0.46,95%CI:0.08-0.84,p=0.02)than trained individuals(ES=0.15,95%CI:-0.23 to 0.53,p=0.45).Interventions lasting a greater number of weeks(>7 weeks)had a larger ES(ES=0.47,95%CI:0.06-0.88,p=0.03)than those lasting fewer weeks(ES=0.22,95%CI:-0.12 to 0.55,p=0.20).Programmes with2 sessions per week(ES=0.20,95%CI:-0.10 to 0.50,p=0.18).Programmes with500 jumps per week had negative effects(ES=-0.22,95%CI:-1.10 to 0.67,p=0.63).Programmes with>7.5 jumps per set showed larger effect sizes(ES=0.55,95%CI:0.02-1.08,p=0.04)than those with7 weeks).

关键词： Jumps Stretch shortening cycle Tendon

Precision silviculture:use of UAVs and comparison of deep learning models for the identification and segmentation of tree crowns in pine crops

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International Journal of Digital Earth 2022年第1期15卷 2223-2238页

作者： Manuel Ignacio Perez Bruno Karelovic Roberto Molina rodrigo saavedra Pierluigi Cerulo Guillermo Cabrera Department of Computer Sciences Universidad de Concepcion Biblioteca CentralConcepcionChile Celulosa Arauco y Constitucion sa I&DSantiagoChile

The monitoring of trees is crucial for the management of large areas of forest cultivations,but this process may be ***,remotely sensed data offers a solution to automate this *** this work,we used two neural network methods named You Only Look Once(YOLO)and Mask R-CNN to overcome the challenging tasks of counting,detecting,and segmenting high dimensional Red–Green–Blue(RGB)images taken from unmanned aerial vehicles(UAVs).We present a processing framework,which is suitable to generate accurate predictions for the aforementioned tasks using a reasonable amount of labeled *** compared our method using forest stands of different ages and *** counting,YOLO overestimates 8.5%of the detected trees on average,whereas Mask R-CNN overestimates a 4.7%of the *** the detection task,YOLO obtains a precision of 0.72 and a recall of 0.68 on average,while Mask R-CNN obtains a precision of 0.82 and a recall of *** segmentation,YOLO overestimates a 13.5%of the predicted area on average,whereas Mask R-CNN overestimates a 9.2%.The proposed methods present a cost-effective solution for forest monitoring using RGB images and have been successfully used to monitor∼146,500 acres of pine cultivations.

关键词： Artificial intelligence tree identification forestry remote sensing

An Online mtDNA Tool for Identification of Neotropical Psittacid Species and Taxonomic Issues:A Study Case of the Amazona ochrocephala Complex

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Natural Resources 2014年第11期5卷 634-652页

作者： Anderson Vieira Chaves rodrigo Octavio de Paiva Queiroz-Filho Fabiano Augusto Assuncao Silva Cristina Yumi Miyaki Fabricio Rodrigues dos sa.tos Departamento de Biologia Geral Instituto de Ciencias Biologicas(ICB)Universidade Federal de Minas GeraisBelo HorizonteBrazil Policia Federal Belo HorizonteBrazil Departamento de Genetica e Biologia Evolutiva Instituto de BiocienciasUniversidade de Sao PauloSao PauloBrazil

Parrots are among the most popular pets in the world and they are also some of the most illegally traded, particularly in Brazil. Some computational tools were recently developed by researchers based on molecular databases for taxonomy support, forensic identification and conservation purposes. In this study, the DNA Surveillance platform was used to build an online database tool for molecular identification of Brazilian Psittacids using DNA sequences of six mitochondrial genes. To illustrate possible taxonomic issues of the online tool due to interspecific hybridization or unresolved taxonomy, we focused on Amazona aestiva that is considered as one of the most common parrots in Brazil, commonly bred as pets, and considered to be part of a species complex with Amazona ochrocephala from South America. We provide three curated sequence databases, which allow the species identification of individuals or tissue samples of birds of the Psittacidae family using mitochondrial DNA markers, and a comprehensive description of a taxonomic issue involving the A. ochrocephala complex. The results obtained corroborate previous studies suggesting that these species are not reciprocally monophyletic, due to either an ancient hybridization in central Brazil, or, they maybe just are morpho-varieties of the same species. Alternatively, if A. aestiva and A. ochrocephala were considered as sister species, the data could be interpreted either as a result of secondary contact or incipient speciation. Beyond the use of mtDNA for species identification, the high mtDNA haplotype diversity observed in A. aestiva indicates its potential use in discrimination of lineages that could be an important auxiliary tool to certify the captive origin of legally commercialized parrots.

关键词： Amazona aestiva Illegal Trade of Birds Psittaciformes Phylogeography DNA-Surveillance

Effects of Tecar Therapy on Adipose Tissue: Clinical Trial

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Journal of Biosciences and Medicines 2022年第4期10卷 169-180页

作者： Patrícia Froes Meyer rodrigo Marcel Valentim Da Silva Eneida De Morais Carreiro Fábio dos sa.tos Borges Stephany Queiroga Felice Picariello Centro Universitario do Rio Grande do Norte UNI-RN Natal Brazil Universidade Federal do Rio Grande do Norte UFRN Natal Brazil Estácio de sa University Rio de Janeiro Brazil Potiguar University UnP Natal Brazil University of the Study of Naples Federico II Nápoles Itália

Introduction: Localised adiposity is one of the leading aesthetic alteration complaints. Tecar therapy has been used in clinical practice for the treatment of fat located in the abdominal region. Objective: The objective is to analyse the effect of Tecar therapy on abdominal adiposity. Methodology: This is a clinical trial in which the participants were 32 female volunteers who have flaccidity and fat located in the abdominal region. The volunteers were divided into three groups, which respectively received applications of the capacitive mode, the resistive mode, and combined therapy of the two modalities. We have performed ten applications and analysed the anthropometric measures, the ultrasonography of the adipose layer, and the level of satisfaction. Results: All groups presented a reduction in perimetry compared to the baseline (p = 0.001). The ultrasonography showed a significant reduction in the combined therapy group compared to the baseline (p = 0.04 and p = 0.03). The level of satisfaction was good in all groups, with few adverse responses. In the bodyweight and percentage of fat analyses, we observed an increase in measurements, probably due to the restriction measures related to the new coronavirus pandemic in 2020. Conclusion: In this present study, we have concluded that Tecar therapy resulted in a reduction of the fat located in the abdominal region.

关键词： Radiofrequency Abdominal Fat Ultrasonography

Neutrophile-to-lymphocyte,lymphocyte-to-monocyte,and platelet-tolymphocyte ratios as prognostic and response biomarkers for resectable locally advanced gastric cancer

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World Journal of Gastrointestinal Oncology 2022年第7期14卷 1307-1323页

作者： Tiago Cruz Tomás Ines Eiriz Marina Vitorino rodrigo Vicente Joao Gramaca Alicia Guadalupe Oliveira Paulo Luz Mafalda Baleiras Ana Sofia Spencer Luísa Leal Costa Patrícia Liu Joana Mendonca Magno Dinis Teresa Padrao Marisol Correia Goncalo Atalaia Michelle Silva Teresa Fiúza Department of Medical Oncology Hospital Professor Doutor Fernando Fonseca EPEAmadora 2720-276Portugal Department of Medical Oncology Centro Hospitalar Barreiro-Montijo EPEBarreiro 2830-003Portugal Department of Medical Oncology Hospital do Espírito Santo deÉvora EPEÉvora 7000-811Portugal Department of Medical Oncology Centro Hospitalar Universitário do Algarve EPEAlgarve 8000-386Portugal Department of Medical Oncology Hospital São Francisco XavierCentro Hospitalar Lisboa Ocidental EPELisboa 1449-005Portugal Department of Medical Oncology Hospital Santo António dos CapuchosCentro Hospital Lisboa Central EPELisboa 1169-050Portugal Department of Medical Oncology Hospital BeatrizÂngeloLoures 2674-514Portugal Department of Medical Oncology Centro Hospitalar de Trás-os-Montes e Alto Douro EPEVila Real 5000-508Portugal Department of Medical Oncology Hospital da Senhora da Oliveira EPEGuimarães 4835-044Portugal Department of Medical Oncology Hospital Garcia de Orta EPEAlmada 2805-267Portugal Department of Medical Oncology Hospital da LuzLisboa 1500-650Portugal Department of Medical Oncology Hospital Distrital de Santarém EPESantarém 2005-177Portugal

BACKGROUND Perioperative fluorouracil plus leucovorin,oxaliplatin,and docetaxel(FLOT)improves prognosis in locally advanced gastric cancer(LAGC).Neutrophil-to-lymphocyte(NLR),lymphocyte-tomonocyte(LMR),and platelet-to-lymphocyte(PLR)ratios are prognostic biomarkers but not predictive *** To assess blood ratios’(NLR,LMR and PLR)potential predictive response to FLOT and survival outcomes in resectable LAGC *** This was a multicentric retrospective study investigating the clinical potential of NLR,LMR,and PLR in resectable LAGC patients,treated with at least one preoperative FLOT cycle,from 12 Portuguese *** were compared through non-parametric Mann-Whitney *** operating characteristic curve analysis defined the cut-off values as:High PLR>141 for progression and>144 for mortality;high LMR>3.56 for T stage regression(TSR).Poisson and Cox regression models the calculated relative risks/hazard ratios,using NLR,pathologic complete response,TSR,and tumor regression grade(TRG)as independent variables,and overall survival(OS)as the dependent *** This study included 295 patients(mean age,63.7 years;59.7% males).NLR was correlated with survival time(r=0.143,P=0.014).PLR was associated with systemic progression during FLOT(P=0.022)and mortality(P=0.013),with high PLR patients having a 2.2-times higher risk of progression[95% confidence interval(CI):0.89-5.26]and 1.5-times higher risk of mortality(95%CI:0.92-2.55).LMR was associated with TSR,and high LMR patients had a 1.4-times higher risk of achieving TSR(95%CI:1.01-1.99).OS benefit was found with TSR(P=0.015)and partial/complete TRG(P<0.001).Patients without TSR and with no evidence of pathological response had 2.1-times(95%CI:1.14-3.96)and 2.8-times(95%CI:1.6-5)higher risk of *** Higher NLR is correlated with longer survival *** LMR patients have a higher risk of decreasing T stage,whereas high PLR patients have higher odds of progressing under FLOT a

关键词： Gastric cancer Perioperative fluorouracil plus leucovorin,oxaliplatin,and docetaxel Neutrophil-to-lymphocyte Lymphocyte-to-monocyte Platelet-to-lymphocyte Tumor regression grade

The effects of plyometric jump training on physical fitness attributes in basketball players:A meta-analysis`

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Journal of Sport and Health Science 2022年第6期11卷 656-670,F0003页

作者： rodrigo Ramirez-Campillo Antonio García-Hermoso Jason Moran Helmi Chaabene Yassine Negra Aaron T.Scanlan Department of Physical Activity Sciences Universidad de Los LagosOsorno 5290000Chile Centro de Investigación en Fisiología del Ejercicio Facultad de CienciasUniversidad MayorSantiago 7500000Chile Navarrabiomed Complejo Hospitalario de Navarra(CHN)Universidad Pública de Navarra(UPNA)IdiSNAPamplona 31008Spain Laboratorio de Ciencias de la Actividad Física el Deporte y la SaludUniversidad de Santiago de ChileUSACHSantiago 9170020Chile School of Sport Rehabilitation and Exercise SciencesUniversity of EssexColchesterEssexCO43SQUnited Kingdom Division of Training and Movement Sciences University of PotsdamPotsdam 14469Germany High Institute of Sports and Physical Education KefUniversity of JendoubaLa Manouba 8189Tunisia Research Unit(UR 17JS01 Sport PerformanceHealth&Society)Higher Institute of Sport and Physical Education of Ksar SaîdUniversity of“La Manouba”Rockhampton 2037Tunisia Human Exercise and Training Laboratory School of HealthMedical and Applied SciencesCentral Queensland UniversityRockhamptonQueenslandQLD 4702Australia

Background:There is a growing body of experimental evidence examining the effects of plyometric jump training(PJT)on physical fitness attributes in basketball players;however,this evidence has not yet been comprehensively and systematically ***,our objective was to meta-analyze the effects of PJT on physical fitness attributes in basketball players,in comparison to a control ***:A systematic literature search was conducted in the databases PubMed,Web of Science,and Scopus,up to July ***-reviewed controlled trials with baseline and follow-up measurements investigating the effects of PJT on physical fitness attributes(muscle power,i.e.,jumping performance,linear sprint speed,change-of-direction speed,balance,and muscle strength)in basketball players,with no restrictions on their playing level,sex,or ***’s g effect sizes(ES)were calculated for physical fitness *** a random-effects model,potential sources of heterogeneity were selected,including subgroup analyses(age,sex,body mass,and height)and single training factor analysis(program duration,training frequency,and total number of training sessions).Computation of metaregression was also ***:Thirty-two studies were included,involving 818 total basketball ***(p10 m(ES=0.92),change-of-direction performance time across distances≤40 m(ES=1.15)and>40 m(ES=1.02),dynamic(ES=1.16)and static balance(ES=1.48),and maximal strength(ES=0.57).The meta-regression revealed that training duration,training frequency,and total number of sessions completed did not predict the effects of PJT on physical fitness *** analysis indicated greater improvement

关键词： Exercise therapy Human physical conditioning Resistance training Stretch reflex Team sports

Metabolomics in chronic hepatitis C:Decoding fibrosis grading and underlying pathways

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World Journal of Hepatology 2023年第11期15卷 1237-1249页

作者： Adriana Camargo Ferrasi samara Vitória Granja Lima Aline Faria Galvani Jeany Delafiori Flavia Luísa Dias-Audibert rodrigo Ramos Catharino Giovanni Faria Silva Roberta Rodrigues Praxedes Driele Bretones sa.tos Dayane Trevisan de Macedo Almeida Estela Oliveira Lima Department of Internal Medicine Sao Paulo State UniversityBotucatu 18618-686Brazil Innovare Biomarkers Laboratory University of CampinasCampinas 13083-877Brazil

BACKGROUND Chronic Hepatitis C(CHC)affects 71 million people globally and leads to liver issues such as fibrosis,cirrhosis,cancer,and death.A better understanding and prognosis of liver involvement are vital to reduce morbidity and *** accurate identification of the fibrosis stage is crucial for making treatment decisions and predicting *** used to grade fibrosis include histological analysis and imaging but have *** markers such as molecular biomarkers can offer valuable insights into *** To identify potential biomarkers that might stratify these lesions and add information about the molecular mechanisms involved in the *** Plasma samples were collected from 46 patients with hepatitis C and classified into fibrosis grades F1(n=13),F2(n=12),F3(n=6),and F4(n=15).To ensure that the identified biomarkers were exclusive to liver lesions(CHC fibrosis),healthy volunteer participants(n=50)were also *** untargeted metabolomic technique was used to analyze the plasma metabolites using mass spectrometry and database *** analyses were performed to identify differential biomarkers among *** Six differential metabolites were identified in each grade of *** six-metabolite profile was able to establish a clustering tendency in patients with the same grade of fibrosis;thus,they showed greater efficiency in discriminating *** This study suggests that some of the observed biomarkers,once validated,have the potential to be applied as prognostic ***,it suggests that liquid biopsy analyses of plasma metabolites are a good source of molecular biomarkers capable of stratifying patients with CHC according to fibrosis grade.

关键词： Chronic Hepatitis C Fibrosis Metabolome Biomarkers Plasma Liquid biopsy

Viability of recalcitrant Araucaria angustifolia seeds in storage and in a soil seed bank

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Journal of Forestry Research 2020年第6期31卷 2413-2422页

作者： Ezequiel Gasparin Jose M.R.Faria Anderson CJose Olivia AOTonetti rodrigo Ade Melo Henk W.M.Hilhorst Departamento de Ciencias Florestais Universidade Federal de Santa Maria(UFSM)Avenida Roraima1000CamobiSanta MariaRS 97105-900Brazil Departamento de Ciencias Florestais Universidade Federal de Lavras(UFLA)Caixa Postal 3017LavrasMGBrazi1 Wageningen Seed Lab Laboratory of Plant PhysiologyWageningen UniversityDroevendaalsesteeg 16708 PB WageningenThe Netherlands

Araucaria angustifolia(Bertol.)Kuntze is a representative species of the Mixed Ombrophilous Forest in the Atlantic Forest Biome of *** development of a germplasm conservation protocol for long-term seed bank storage is compromised for this species,as it is sensitive to ***,in situ establishment of a soil seed bank in its natural habitat may be *** study evaluates the storability of two provenances of *** seeds and their behavior in an artificial soil seed bank in two forest environments(understory and edge).Results show that both seed provenances may be stored at 5C for approximately 12 months,retaining high *** subsequent decrease in germination was associated with a reduction and an increase in seed water content,as well as with increased electrical *** the understory environment,seed viability was above 85%for the first 60 days,and at the end of the experiment(270 days),seedlings ***,at the forest edge,there was a total loss of seed viability after 120 days associated with a reduction in water content and high *** is concluded,therefore,that short-term storage of *** seeds is possible in a cold room,which is fundamental to supply seed demand outside the production *** cover conservation is important for regeneration and conservation of the species.

关键词： Brazilian pine Desiccation sensitivity Forest cover Soil seed bank Storability