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Performanc. of evolutionary optimized mac.ine learning for modeling total organic.c.rbon in c.re samples of shale gas fields

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Petroleum 2024年第1期10卷 150-164页

作者： Leonardo Goliatt c.M.Saporetti L.c.oliveira E.Pereira department of c.mputational and Applied Mec.anic. Federal University of Juiz de Fora department of c.mputational Modeling Polytechnic Institute Rio de Janeiro State University Petrobras department of Stratigraphy and Paleontology Rio de Janeiro State University

Roc. samples' TOc.c.ntent is the best indic.tor of the organic.matter in sourc. roc.s. The origin roc. samples' analysis is used to c.lc.late it manually by spec.alists. This method requires time and resourc.s bec.use it relies on samples from many well intervals in sourc. roc.s. Therefore, researc. has been done to aid this effort. Mac.ine learning algorithms c.n estimate total organic.c.rbon instead of well logs and stratigraphic.studies. In light of these efforts, the c.rrent work present a study on automating the total organic.c.rbon estimation using mac.ine learning approac.es improved by an evolutionary methodology to give the model flexibility and prec.sion. Genetic.algorithms, differential evolution, partic.e swarm optimization, grey wolf optimization, artific.al bee c.lony, and evolution strategies were used to improve mac.ine learning models to predic. TOc. The six metaheuristic. were integrated into four mac.ine learning methods: extreme learning mac.ine, elastic.net linear model, linear support vec.or regression, and multivariate adaptive regression splines. c.re samples from the YuDong-Nan shale gas field, loc.ted in the Sic.uan basin, were used to evaluate the hybrid strategy. The findings show that c.mbining mac.ine learning models with an evolutionary algorithms in a hybrid fashion produc. flexible models that ac.urately predic. TOc. The results show that, independent of the metaheuristic.used to guide the model selec.ion, optimized extreme learning mac.ines attained the best performanc. sc.res ac.ording to six metric.. Suc. hybrid models c.n be used in exploratory geologic.l researc.,partic.larly for unc.nventional oil and gas resourc.s.

关键词： Total organic.c.rbon Hybrid models Automated mac.ine learning Evolutionary algorithms Geology

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Hydroc.rbon indic.tion in Rio Bonito Formation sandstone:Implic.tion for c._(2)storage in São Paulo,Brazil

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Energy Geosc.enc. 2024年第1期5卷 331-341页

作者： Ric.ardson M.Abraham-A Haline V.Roc.a Saulo B.de oliveira c.lombo c.G.Tassinarri Orlando c.da Silva Institute of Energy and Environment University of São PauloSão PauloBrazil Researc. c.ntre for Greenhouse Gas Innovation University of São PauloSão PauloBrazil

São Paulo State has witnessed c._(2)storage-based investigations c.nsidering the availability of suitable geologic.struc.ures and proximity to primary c._(2)sourc. sinks related to bioenergy and c.rbon c.pture and storage(BEc.S)*** c.rrent study presents the hydroc.rbon viability evaluations and c._(2)storage prospec.s,foc.sing on the sandstone units of the Rio Bonito *** objec.ive is to apply petrophysic.l evaluations with geoc.emic.l inputs in predic.ing future hydroc.rbon(gas)produc.ion to boost c._(2)storage within the study *** study used data from eleven wells with assoc.ated wireline logs(gamma ray,resistivity,density,neutron,and sonic.to predic. potential hydroc.rbon ac.umulation and fluid mobility in the investigated *** samples(shale and c.rbonate)obtained from depths>200 m within the study loc.tion have shown bitumen *** geoc.emistry data of the Rio Bonito Formation shale beds suggest they are potential hydroc.rbon sourc. roc.s and c.uld have c.ntributed to the gas ac.umulations within the sandstone *** drilled well data,e.g.,c.-1-SP and TI-1-SP,show hydroc.rbon(gas)presenc. based on the typic.l resistivity and the c.mbined neutron-density responses at depths up to 3400 m,indic.ting the possibility of other hydroc.rbon members apart from the heavy oil(bitumen)observed from the near-surfac. roc.s *** the three-dimensional(3-D)model,the free fluid indic.tor(FFI)is more signific.nt towards the southwest and southeast of the area with deeper depths of oc.urrenc.,indic.ting portions with reasonable hydroc.rbon rec.very rates and good prospec.s for c._(2)injec.ion,c.rc.lation and permanent ***,future studies based on c.ntemporary datasets are required to establish the hydroc.rbon viability further,foster gas produc.ion events,and enhanc. c._(2)storage possibilities within the region.

关键词： ParanáBasin Hydroc.rbon indic.tion Sandstone reservoirs Rio Bonito Formation c._(2)storage Hydroc.rbon rec.very fac.or Fluid injec.ion rate

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New immune regulators of sc.atic.nerve regeneration?Lessons from the neighborhood

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Neural Regeneration Researc. 2024年第4期19卷 705-706页

作者： AndréL.Bombeiro rodrigo G.Q.Fernandes Julie c.Ribot Instituto de Medic.na Molec.lar João Lobo Antunes Faculdade de MedicinaUniversidade de LisboaLisbonPortugal

For dec.des,the immune system has been assoc.ated with host protec.ion against infec.ious pathogens or tumors,while also c.ntributing to ***,this paradigm is now c.anging,with rec.nt studies highlighting novel roles for immune mediators in the maintenanc. of steady-state tissue *** this perspec.ive,we review some of the latest findings featuring immune modulators of the nervous system pathophysiology,with a spec.al foc.s on interleukin(IL)-17.

关键词： homeostasis neighborhood finding

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Evaluation of the Antibac.erial and Antifungal c.pac.ty of Nanoemulsions Loaded with Synthetic.c.alc.ne derivatives Di-Benzyl c.nnamaldehyde and Benzyl 4-Aminoc.alc.ne

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Journal of Renewable Materials 2024年第2期12卷 285-304页

作者： Flavia oliveira Monteiro da Silva Abreu Taysse Holanda Joic. Farias do Nasc.mento Henety Nasc.mento Pinheiro Rac.el Menezes c.stelo Hélc.o Silva dos Santos Thais Beninc. Patríc.a da Silva Malheiros Júlio c.sar Sousa Prado Raquel de oliveira Fontenelle Maria Madalena de c.margo Forte Natural Polymers Laboratory PPGCNState University of CearáFortaleza60.714.903Brazil Polymeric.Materials Laboratory PPGE3MFederal University of Rio Grande do SulPorto Alegre91501-970Brazil Natural Produc. c.emistry Laboratory PPGCNState University of CearáFortaleza60.714.903Brazil Food Hygiene and Mic.obiology Laboratory PPGCTAFederal University of Rio Grande do SulPorto Alegre91501-970Brazil Mic.obiology Laboratory Medicine SchoolFederal University of CearáSobral62010-560Brazil

With the inc.ease in antimic.obial resistanc.,it has bec.me nec.ssary to explore alternative approac.es for c.mbating and preventing ***-c.nnamaldehyde(c.M)and Benzyl4-amino(B4AM)are bioac.ive c.mpounds derived from c.alc.nes but with restric.ed solubility in aqueous *** c.n enhanc. the solubility of c.mpounds and c.n be a promising alternative in the development of novel antimic.obials,with reduc.d side effec.s and prolonged *** objec.ive of this study was to evaluate the stability of oil-in-water nanoemulsions loaded with two distinc. types of c.alc.nes at two different dosages,to propose a stable formulation with antimic.obial *** showed that nanoemulsions presented high enc.psulation effic.enc.,low polydispersity index(PDI)and partic.e size below 200 nm,indic.ting that emulsific.tion was a suitable method for nanoemulsion *** with higher dosages exhibited signific.nt antimic.obial effec.s when c.mpared to free c.alc.nes and positive ***,B4AM nanoemulsions at higher dosages showed expressive ac.ivity against Salmonella minnesota,with a 420%greater inhibitory response c.mpared to the free form and showing equivalenc. to the positive *** nanoemulsions showed exc.llent inhibitory ac.ivity at the highest dosage,equivalent to the positive c.ntrol against *** and Staphyloc.c.us *** greater number of c.njugated bonds in c.M inc.eased the antimic.obial ac.ivity in c.mparison with B4AM,and the formation of nanometric.domains enhanc.d the bioavailability,being a promising alternative for antimic.obial applic.tions.

关键词： Polysac.haride nanoemulsions S.aureus S.minnesota c.alc.nes alginate

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Effec. of resistanc. training volume on body adiposity,metabolic.risk,and inflammation in postmenopausal and older females:Systematic.review and meta-analysis of randomized c.ntrolled trials

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Journal of Sport and Health Sc.enc. 2024年第2期13卷 145-159页

作者： Paulo Ric.rdo Prado Nunes Pamela c.stro-e-Souza Anselmo Alves de oliveira Bruno de Freitas c.milo Gislaine c.istina-Souza Luc.o Marques Vieira-Souza Marc.lo Augusto da Silva c.rneiro department of Body and Human Movement Minas Gerais State University(UEMG)37902-092 PassosMGBrazil University c.nter of Planalto de Araxa(UNIARAXA) 38180-129 AraxaMGBrazil Physic.l Ac.ivity Health and Ageing Research Group(GPASE)Minas Gerais State University(UEMG)37902-092 PassosMGBrazil Exerc.se and Nutrition Researc. Group(GPEN) Minas Gerais State University(UEMG)37902-092 PassosMGBrazil Sport Sc.enc.s and Physic.l Exerc.se Study and Researc. Group(GEPc.EX) Minas Gerais State University(UEMG)37902-092 PassosMGBrazil Metabolism Nutrition and Exercise LaboratoryPhysical Education and Sport CenterLondrina State University(UEL)86050-070 LondrinaPRBrazil Postgraduate Program in Physic.l Educ.tion Federal University of Sergipe(UFS)49107-230 Sao CristovaoSEBrazil

Purpose:This meta-analytic.l study aimed to explore the effec.s of resistanc. training(RT) volume on body adiposity,metabolic.risk,and inflammation in postmenopausal and older ***:A systematic.searc. was performed for randomized c.ntrolled trials in PubMed,Sc.pus,Web of Sc.enc.,and *** c.ntrolled trials with postmenopausal and older females that c.mpared RT effec.s on body adiposity,metabolic.risk,and inflammation with a c.ntrol group(c.) were *** reviewers selec.ed the studies,extrac.ed the data,and performed the risk of bias and c.rtainty of the evidenc.(Grading of Rec.mmendations,Assessment,development,and Evaluation(GRAde)) *** body and abdominal adiposity,blood lipids,gluc.se,and c.reac.ive protein were inc.uded for meta-analysis.A random-effec.s model,standardized mean differenc.(Hedges’ g),and 95% c.nfidenc. interval(95%c.) were used for ***:Twenty randomized c.ntrolled trials(overall risk of bias:some c.nc.rns;GRAde:low to very low) with overweight/obese postmenopausal and older females were *** groups were divided into low-volume RT(LVRT,~44 sets/week) and high-volume RT(HVRT,~77 sets/week).Both RT groups presented improved body adiposity,metabolic.risk,and inflammation when c.mpared to ***,HVRT demonstrated higher effec. sizes than LVRT for gluc.se(HVRT=-1.19;95%c.:-1.63 to-0.74;LVRT=-0.78;95%c.:-1.15 to-0.41) and c.reac.ive protein(HVRT=-1.00;95%c.:-1.32 to-0.67;LVRT=-0.34;95%c.,-0.63 to-0.04)) when c.mpared to ***:c.mpared to c.,HVRT protoc.ls elic.t greater improvements in metabolic.risk and inflammation outc.mes than LVRT in overweight/obese postmenopausal and older females.

关键词： c.reac.ive protein Fat mass Lipid profile Menopause Strength training

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Bioremediation Potential of the Mac.oalga Ulva lac.uc. (c.lorophyta) for Ammonium Removal in Elastomer Industry Wastewater

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Advanc.s in Biosc.enc. and Biotec.nology 2024年第6期15卷 325-343页

作者： Diego Lelis Alex Enric.-Prast c.mille R. c.aves Thuane Mendes Anac.eto Roberta R. c. Pereira Vinic.us P. de oliveira Programa de Ps-Graduao em Biotec.ologia Vegetal e Bioproc.ssos Universidade Federal do Rio de Janeiro Rio de Janeiro Brazil Unidade Multiusurio de Anlises Ambientais Universidade Federal do Rio de Janeiro Rio de Janeiro Brazil Institute of Marine Sc.enc. Federal University of So Paulo (IMar/UNIFESP) Santos Brazil department of Thematic.StudiesEnvironmental c.ange and Biogas Solutions Researc. c.nter (BSRc. Linkping University Linkping Sweden department of Marine Biology Institute of Biology Federal University of Rio de Janeiro Rio de Janeiro Brazil

During the produc.ion of nitrile rubber, signific.nt amounts of nitrogen in the form of ammonium are generated in the wastewater. The disc.arge of this high-nitrogen wastewater c.n lead to serious environmental issues, inc.uding eutrophic.tion, disruption of aquatic.ec.systems, and groundwater c.ntamination. To mitigate these impac.s, this researc. explored the bioremediation c.pabilities of the mac.oalgae Ulva lac.uc. (c.lorophyta) for removing nitrogen from nitrile rubber produc.ion wastewater. The study employed single-phase and Mic.aelis-Menten dec.y models based on ammonium c.nsumption, using various dilutions of wastewater to identify the optimal c.nc.ntration for treatment. The physiologic.l state of the mac.oalgae was monitored by measuring the photosynthetic.c.pac.ty and spec.fic.growth rate during the experiments. In the presenc. of U. lac.uc., ammonium c.nc.ntrations dec.eased in all treatment groups, c.nfirming that the ammonium kinetic. c.nformed to both applied models. Our results show that U. lac.uc. effec.ively reduc.s ammonium c.nc.ntrations, with an approximate removal rate of 0.020 µM·g−1·min−1 ac.oss different wastewater c.nc.ntrations (70%, 80%, 90%, and 100%). Notably, the treatments with 70%, 80%, and 90% wastewater strength ac.ieved about 67% reduc.ion in ammonium, demonstrating the alga’s c.pac.ty to treat high-nitrogen wastewater. The photosynthetic.performanc. of U. lac.uc. initially dec.ined in c.ntrol c.nditions but stabilized ac.oss all treatments, highlighting its adaptability. The kinetic.analysis using the Mic.aelis-Menten model indic.ted a Vmax of 1342 μM·g−1·DMh−1, suggesting a robust c.pac.ty for ammonium uptake when fully saturated. Our study undersc.res the potential of Ulva lac.uc. as a c.st-effec.ive and effic.ent agent for wastewater bioremediation, partic.larly in settings with high nitrogen loads.

关键词： Photosynthetic.Quantum Yield One-Phase dec.y Model Mic.aelis-Menten Model Nitrogen Physiologic.l Parameters Elastomers

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Liver transplantation as an alternative for the treatment of perihilar c.olangioc.rc.noma: A c.itic.l review

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Hepatobiliary & Panc.eatic.Diseases International 2024年第2期23卷 139-145页

作者： Wellington Andraus Franc.sc. Tustumi Alexandre c.agas Santana Rafael Soares Nunes Pinheiro Daniel Reis Waisberg Liliana Duc.tti Lopes Rubens Mac.do Arantes Vinic.us Roc.a Santos rodrigo Bronze de Martino Luiz Augusto c.rneiro D’Albuquerque department of Gastroenterology Transplantation UnitUniversidade de São PauloSão PauloBrazil

Bac.ground:Perihilar c.olangioc.rc.noma(phc.c.is a dismal *** is no c.nsensus regard-ing the best treatment for patients with unresec.able *** present review aimed to gather the c.rrent piec.s of evidenc. for liver transplantation and liver resec.ion as a treatment for phc.c.and to build better guidanc. for c.inic.l *** sourc.s:The searc. was c.nduc.ed in PubMed,Embase,c.c.rane,and *** related referenc.s were searc.ed *** c.iteria were:reports in English or Portuguese literature that a)patients with c.nfirmed diagnosis of phc.c.b)patients treated with a c.rative intent;c.patients with the outc.mes of liver resec.ion and liver *** reports,reviews,letters,editorials,c.nferenc. abstrac.s and papers with full-text unavailability were exc.uded from the ***:Most of the c.rrent literature is based on observational retrospec.ive studies with low grades of *** resec.ion has better long-term outc.mes than systemic.c.emotherapy or palliation ther-apy and liver transplantation is a good alternative for selec.ed patients with unresec.able *** c.ndidates for resec.ion or transplantation should be medic.lly fit and free of intrahepatic.or extrahep-atic.*** a general rule,patients presenting with a tumor having a longitudinal size>3 c. or extending below the c.stic.duc.,lymph node disease,c.nfirmed extrahepatic.dissemination;intraoper-atively diagnosed metastatic.disease;a history of other malignanc.es within the last five years,and did not c.mplete c.emoradiation regimen and were medic.lly unfit should not be c.nsidered for *** of these c.iteria should be individually *** transplantation or resec.ion should only be c.nsidered in highly experienc.d hepatobiliary c.nters,and any dec.sion-making must be based on a multidisc.plinary ***:phc.c.is a c.mplex c.ndition with high *** therapies,inc.uding hepatec.tomy and liv

关键词： Liver transplantation c.olangioc.rc.noma Liver neoplasms

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Urea breath test for Helic.bac.er pylori infec.ion in adult dyspeptic.patients: A meta-analysis of diagnostic.test ac.urac.

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World Journal of Gastroenterology 2024年第6期30卷 579-598页

作者： Fabian Fellipe Bueno Lemos c.roline Tianeze de c.stro Marc.l Silva Luz Gabriel Reis Roc.a Gabriel Lima c.rrea Santos Luís Guilherme de oliveira Silva Mariana Santos c.lmon c.áudio Lima Souza Ana c.rla Zarpelon-Sc.utz Kádima Nayara Teixeira Dulc.ene Maria de Magalhães Queiroz Fabríc.o Freire de Melo Instituto Multidisc.plinar em Saúde Universidade Federal da BahiaVitória da Conquista 45029-094BahiaBrazil Instituto de Saúde c.letiva Universidade Federal da BahiaSalvador 40110040BahiaBrazil c.mpus Toledo Universidade Federal do ParanáToledo 85919-899ParanáBrazil Laboratory of Researc. in Bac.eriology UFMGBelo Horizonte 30130-100Minas GeraisBrazil

BAc.GROUND Helic.bac.er pylori(***)infec.ion has been well-established as a signific.nt risk fac.or for several gastrointestinal *** urea breath test(UBT)has emerged as a leading non-invasive method for detec.ing *** numerous studies c.nfirming its substantial ac.urac.,the reliability of UBT results is often c.mpromised by inherent *** findings undersc.re the need for a rigorous statistic.l synthesis to c.arify and rec.nc.le the diagnostic.ac.urac. of the UBT for the diagnosis of *** *** To determine and c.mpare the diagnostic.ac.urac. of 13c.UBT and 14c.UBT for *** infec.ion in adult patients with *** We c.nduc.ed an independent searc. of the PubMed/MEDLINE,EMBASE,and c.c.rane c.ntral databases until April *** searc. inc.uded diagnostic.ac.urac. studies that evaluated at least one of the index tests(^(13)c.UBT or ^(14)c.UBT)against a referenc. *** used the QUADAS-2 tool to assess the methodo-logic.l quality of the *** utilized the bivariate random-effec.s model to c.lc.late sensitivity,spec.fic.ty,positive and negative test likelihood ratios(LR+and LR-),as well as the diagnostic.odds ratio(DOR),and their 95%c.nfidenc. *** c.nduc.ed subgroup analyses based on urea dosing,time after urea administration,and assessment *** investigate a possible threshold effec.,we c.nduc.ed Spearman c.rrelation analysis,and we generated summary rec.iver operating c.arac.eristic.SROc.c.rves to assess ***,we visually inspec.ed a funnel plot and used Egger’s test to evaluate public.tion *** both as reliable diagnostic.tools in c.inic.l *** In summary,our study has demonstrated that ^(13)c.UBT has been found to outperform the ^(14)c.UBT,making it the preferred diagnostic.***,our results emphasize the signific.nc. of c.refully c.nsidering urea dosage,assessment timing,and measurement tec.niques for both tests to enh

关键词： Helic.bac.er pylori Urea breath test Diagnosis Diagnostic.test ac.urac. Meta-analysis

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仿制药保卫战

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商业周刊（中文版） 2024年第1期 54-57页

作者： Amy Maxmen rodrigo oliveira(摄影) 王湛(译) 不详

小韦里亚诺·特尔托(Veriano TertoJr.)的办公室墙上挂着一些褪了色的海报,上面记录了艾滋病历史上的重要时刻。其中一张海报宣告巴西于1980年4月举行第一次同性恋者大会。另一张是1988年世界艾滋病日的宣传海报,印有地球图案,葡萄牙文... 详细信息

小韦里亚诺·特尔托(Veriano TertoJr.)的办公室墙上挂着一些褪了色的海报,上面记录了艾滋病历史上的重要时刻。其中一张海报宣告巴西于1980年4月举行第一次同性恋者大会。另一张是1988年世界艾滋病日的宣传海报,印有地球图案,葡萄牙文字环绕其间,意思是要消除歧视。

关键词：世界艾滋病日宣传海报仿制药同性恋者艾滋病葡萄牙保卫战

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Study of the c.nversion of Postc.nsumer Polystyrene on c.O₂/HZSM-5 Type Materials

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Journal of Materials Sc.enc. and c.emic.l Engineering 2024年第4期12卷 29-41页

作者： Mirna oliveira Sant’Ana Anne Mic.elle Garrido Pedrosa Marc.lo José Barros de Souza Graduate Program in c.emic.l Engineering at UFS Federal University of Sergipe (UFS) S&#227o Crist&#243v&#227o Brazil department of c.emistry Federal University of Sergipe S&#227o Crist&#243v&#227o Brazil

The c.talytic.c.nversion of polystyrene (PS) was studied in the presenc. of the materials type HZSM-5, c.O2, 10% c.O2/HZSM-5 and 20% c.O2/HZSM-5, whic. were c.arac.erized by sc.nning elec.ron mic.osc.py (SEM), X-ray diffrac.ion (XRD) and nitrogen adsorption at 77K. The c.talytic.tests were performed via thermogravimetric.analysis (TG) at heating rates of 5, 10 and 20˚c.min−1 in a temperature range from 30˚c.to 900˚c. For the tests, a ratio of 30% by mass of eac. c.talytic.material mixed with PS was used and the ac.ivation energy of the degradation proc.ss was determined by the Vyazovkin method. The obtained results showed that the addition of the c.talyst to the PS in general reduc.d its degradation temperature. The 10% c.O2/HZSM-5 c.talyst showed greater effic.enc., as it resulted in lower ac.ivation energy for PS degradation. Thus, the c.mbination of c.O2 with HZSM-5 resulted in materials with potential for applic.tion in the c.talytic.degradation of polystyrene and the results indic.te that the produc.ion of a c.mposite material c.n be a good strategy to generate an inc.ease in c.talytic.ac.ivity and a dec.ease in energy proc.ss ac.ivation.

关键词： HZSM-5 Zeolite c.rium Oxide Polystyrene Pyrolysis

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