检索结果-南通市图书馆

Access control technologies for Big Data management systems:literature review and future trends

在线全文

学校读者我要写书评

暂无评论

Cybersecurity 2019年第1期2卷 63-75页

作者： pietro Colombo Elena Ferrari DiSTA University of InsubriaVia Mazzini 521100 VareseItaly

Data security and privacy issues are magnified by the volume,the variety,and the velocity of Big Data and by the lack,up to now,of a reference data model and related data manipulation *** this paper,we focus on one of the key data security services,that is,access control,by highlighting the differences with traditional data management systems and describing a set of requirements that any access control solution for Big Data platforms may *** then describe the state of the art and discuss open research issues.

关键词： Big Data Access control Privacy NoSQL data management systems

A long story for a short peptide:therapeutic efficacy of a cleavagespecific tau antibody

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2021年第12期16卷 2417-2419页

作者： Giuseppina Amadoro Valentina Latina pietro Calissano Institute of Translational Pharmacology(IFT)-National Research Council(CNR) Via Fosso del Cavaliere 10000133-RomeItaly(Amadoro G)European Brain Research Institute(EBRI)Viale Regina Elena 29500161-RomeItaly

Tau is the prime participant in the Alzheimer’s disease(AD) neurodegeneration:AD,the main cause of dementia in elderly people,is a multifactorial neurodegenerative disorder characterized by a long prodromal phase(starting more than two decades before clinical symptoms appear)with brain accumulation/misfolding of amyloidβ(Aβ)in insoluble amyloid plaques and of tau protein in neurofibrillary tangles.

关键词： tau Aβ Alzheimer

AtSYP51/52 Functions Diverge in the Post-Golgi Traffic and Differently Affect Vacuolar Sorting

在线全文

学校读者我要写书评

暂无评论

Molecular Plant 2013年第3期6卷 916-930页

作者： Maria de Benedictis Gianluca Bleve Marianna Faraco Egidio Stigliano Francesco Grieco Gabriella Piro Giuseppe Dalessandro Gian pietro Di Sansebastiano Dipartimento di Scienze e Tecnologie Biologiche ed Ambientali University of Salento Campus Ecotekne 73100 Lecce Italy Present address: Dipartimento di Bioscienze Universita degli Studi di Parma Parco Area delle Scienze 11/A 43124 Parma Italy Institute of Science of Food Production National Research Council via Provinciale Lecce-Monteroni 73100 Lecce Italy Laboratory of Cell and Molecular Biology University of Neuchatel Rue Emile-Argand 11 CP 158 2009 Neuchatel Switzerland

Plant sensitive factor attachment protein receptors （SNAREs） encoded by genes of the same sub-family are generally considered as redundant in promoting vesicle-associated membrane fusion events. Nonetheless, the application of innovative experimental approaches highlighted that members of the same gene sub-family often have different functional specificities. In this work, two closely related Qc-SNAREs--the AtSYP51 and the AtSYP52--are compared in their ability to influence different secretory pathways. Their role in the vesicle sorting to the central vacuole has been revised and they were found to have a novel inhibitory function. When transiently overexpressed, the SYP51 and the SYP52 distributed between the TGN and the tonoplast. Our data demonstrate that these SYPs （syntaxin of plants） act as t-SNARE when present on the membrane of TGN/PVC, whereas they behave as inhibitory or interfering SNAREs （i-SNAREs） when they accumulate on the tonoplast. Moreover, the performed functional analysis indicated that the AtSYP51 and the AtSYP52 roles differ in the traffic to the vacuole. The findings are a novel contribution to the functional characterization of plant SNAREs that reveals additional non-fusogenic roles.

关键词： endocytosis endosome Golgi i-SNARE plant endomembranes protoplast SNARE TGN tonoplast vacuole.

Synergy of human platelet lysate and laminin to enhance the neurotrophic effect of human adipose-derived stem cells

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2022年第10期17卷 2200-2202页

作者： pietro G di Summa Srinivas Madduri department of Plastic Reconstructive and Hand SurgeryUniversity Hospital of LausanneUniversity of LausanneLausanneSwitzerland department of Surgery Bioengineering and NeuroregenerationUniversity of GenevaUniversity Hospital GenevaGenevaSwitzerland

despite the spontaneous regenerative capacity of the peripheral nervous system,clinical nerve repair often results in poor functional recovery with the high socio-economic *** presence of peripheral nerve injuries and when distal nerve transfers are not possible,nerve autografts,are the solution of choice to cross a critical nerve ***,these are associated with donor site morbidity and offer only suboptimal functional ***,the need to improve the rate of effective regeneration has directed research attention towards stem cell therapy and nerve tissue engineering.

关键词： injuries donor spite

Dynamical interactions of dark energy and dark matter:Yang-Mills condensate and QCD axions

在线全文

学校读者我要写书评

暂无评论

Chinese Physics C 2018年第7期42卷 103-112页

作者： Andrea Addazi pietro Donà Antonino Marcianò department of Physics&Center for Field Theory and Particle Physics Fudan University200433 ShanghaiChina Institute for Gravitation and the Cosmos&Physics department Penn StateUniversity ParkPA 16802USA

We analyze a model of cold axion dark matter weakly coupled with a dark gluon condensate, reproducing dark energy. We first review how to recover the dark energy behavior using the functional renormalization group approach, and ground our study in the properties of the effective Lagrangian, to be determined non-perturbatively. Then, within the context of GSM×SU（2）D×U（1）PQ, we consider Yang-Mills condensate （YMC） interactions with QCD axions. We predict a transfer of dark energy density into dark matter density, that can be tested in the next generation of experiments dedicated to dark energy measurements. We obtain new bounds on the interactions between the Yang-Mills condensate and axion dark matter from Planck data：the new physics interaction scale related to the axion/gluon condensate mixing is constrained to be higher than the 106 GeV energy scale.

关键词： dark matter dark energy axion peccei-quinn

A Double Assessment of Privacy Risks Aboard Top‑Selling Cars

在线全文

学校读者我要写书评

暂无评论

Automotive Innovation 2023年第2期6卷 146-163页

作者： Giampaolo Bella pietro Biondi Giuseppe Tudisco Dipartimento di Matematica e Informatica Universitàdegli Studi di CataniaCataniaItaly Osservatorio Astrofisico di Catania Istituto Nazionale di AstrofisicaCataniaItaly

The advanced and personalised experience that modern cars offer makes them more and more *** example,the cabin preferences of the possible drivers must be recorded and associated to some identity,while such data could be exploited to deduce sensitive information about the driver’s ***,drivers’privacy must be taken seriously,requiring a dedicated risk assessment framework,as presented in this paper through a double assessment combining the asset-oriented ISO approach with the threat-oriented STRIde *** framework is tailored to the level of specific car brand and demonstrated on the ten top-selling brands as well as,due to its innovative character,*** two approaches yield different,but complementary findings,demonstrating the additional insights gained through their parallel adoption.

关键词： Automotive Cyber physical systems Risk management ISO 27005 STRIde

An Experimental Investigation of the Dissipation Mechanisms in the Suction Side Boundary Layer of a Turbine Blade

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Thermal Science 2008年第4期17卷 289-297页

作者： Francesca Satta Daniele Simoni Marina Ubaldi pietro Zunino Dipartimento di Macchine Sistemi Energetici e Trasporti-Università di Genova

The present work is part of an extensive experimental activity carried out by the authors in recent years aimed at investigating the boundary layer transition phenomenon in turbine blades. The large scale of the cascade and the use of advanced LDV instrumentation and precision probe traversing mechanism resulted in high degree of spatial resolution and high accuracy of measurements. The main dissipation mechanism determining the profile losses in turbomachinery blades is the work of deformation of the mean motion within the boundary layer operated by both viscous and turbulent shear stresses. In the present paper, the local viscous and turbulent deformation works have been directly evaluated from the detailed measurements of boundary layer mean velocity and Reynolds shear stress. The results show the distributions and the relative importance of the viscous and turbulent contributions to the loss production, in relation with the boundary layer states occurring along the turbine profile.

关键词： Axial flow turbines Profile boundary layer Energy dissipation mechanism Boundary layer transition Laser Doppler measurements.

A Chopper Negative-R delta-Sigma ADC for Audio MEMS Sensors

在线全文

学校读者我要写书评

暂无评论

Computer Modeling in Engineering & Sciences 2022年第2期130卷 607-631页

作者： Jamel Nebhen pietro M.Ferreira College of Computer Engineering and Sciences Prince Sattam bin Abdulaziz UniversityAlkharj11942Saudi Arabia Universit´e Paris-Saclay Centrale SupelecCNRSLaboratory de G´enie Electrique et Electronique de ParisGif-sur-Yvette91192France Sorbonne Universite CNRSLab.de Genie Electrique et Electronique de ParisParis75252France

This paper presents a proposed low-noise and high-sensitivity Internet of Thing(IoT)system based on an M&NEMS *** IoT device consists of an M&NEMS resistive accelerometer associated with an electronic readout circuit,which is a silicon nanowire and a Continuous-Time(CT)△∑*** first integrator of the△∑ADC is based on a positive feedback DC-gain enhancement two-stage amplifier due to its high linearity and low-noise *** mitigate both the offset and 1/f noise,a suggested delay-time chopper negative-R stabilization technique is applied around the first integrator.A 65-nm CMOS process implements the CT△∑*** supply voltage of the CMOS circuit is 1.2-V while 0.96-mW is the power consumption and 0.1-mm^(2) is the silicon *** M&NEMS microphone and△∑ADC complete circuit are fabricated and *** a working frequency bandwidth of 20-kHz,the measurement results of the proposed IoT system reach a signal to noise ratio(SNR)of ***,it has a measured dynamic range(DR)of 108-dB and a measured signal to noise and distortion ratio(SNDR)of 101.3-dB.

关键词： M&NEMS sensor △∑ ADC chopper negative-R IoT 1/f noise SNR

Long-term complete response in metastatic poorly-differentiated neuroendocrine rectal carcinoma with a multimodal approach: A case report

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Oncology 2021年第6期12卷 500-506页

作者： Silvia della Torre Germana de Nucci pietro Maria Lombardi Samuele Grandi Gianpiero Manes roberto Bollina Oncology Unit ASST RhodenseRho 20017Italy department of Gastroenterology Garbagnate Milanese HospitalASST RhodenseGarbagnate Milanese 20024Italy Minimally Invasive Surgery Division Niguarda HospitalMilan 20110Italy Robotic and Emergency Surgery General Surgery DivisionManzoni HospitalLecco 23900Italy Gastroenterology Unit ASST Rhodense-Garbagnate MilaneseGarbagnate Milanese 20054Italy

BACKGROUND Neuroendocrine gastrointestinal tumors(NETs)are rare and have different natural *** is the gold standard treatment for local disease while radiotherapy has been demonstrated to be *** differentiated neuroendocrine carcinomas(NECs)represent only 5%-10%of digestive *** to aggressive growth and rapid metastatic diffusion,early diagnosis and a multidisciplinary approach are *** role of surgery and radiotherapy in this setting is still debated,and chemotherapy remains the treatment of *** SUMMARY A 42-year-old male with an ulcerated bleeding rectal lesion was diagnosed with a NEC G3(Ki67 index>90%)on May 2015 and initially treated with 3 cycles of first-line chemotherapy,but showed early local progressive disease at 3 mo and underwent sphincter-sparing open anterior low rectal *** September 2015,the first post-surgery total-body computed tomography(CT)scan showed an early pelvic disease ***,systemic chemotherapy with FOLFIRI was started and the patient obtained only a partial *** was followed by pelvic radiotherapy(50 Gy).On April 2016,a CT scan and 18F-fluorodeoxy-glucose positron emission tomography imaging showed a complete response(CR)of the pelvic lesion,but pathological abdominal inter-aortocaval lymph nodes were *** to disease progression of abdominal malignant nodes,the patient received radiotherapy at 45 Gy,and finally obtained a *** of January 2021,the patient has no symptoms of relapse and no late toxicity after chemotherapy or *** This case demonstrates how a multimodal approach can be successful in obtaining long-term CR in metastatic sites in patients with high grade digestive NECs.

关键词： Neuroendocrine tumor Multimodal therapy Rectal carcinoma Surgery Radiotherapy Case report