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AN INVESTIGATION INTO TENANT ORGANIZATIONS' WIllINGNESS-TO-PAY FOR THE INTANGIBlE VAlUE-ADDED BENEFITS OF SUSTAINABlE BUIlDINGS:CASE STUDY IN SINGAPORE

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Journal of Green Building 2015年第3期10卷 191-213页

作者： Irene Y.l.lee Huiyu Chen robert l.k.tiong Building Research Institute Housing&Development Board480 Lorong 6 Toa Payoh Singapore 310480 School of Civil and Environmental Engineering Nanyang Technological UniversityBlock N1Nanyang AvenueSingapore 639789

This research aims to understand the demand for sustainable buildings by inves-tigating the tenant organizations’willingness-to-pay(WTP)behavior towards the value-added benefits(VABs).Tenant organizations refer to tenants operating in office buildings on tenancy *** groups of factors of tenant organi-zations’WTP for the VABs are identified:(1)Organization Characteristics,(2)Current Premises,(3)Building Characteristics,(4)Satisfaction of the VABs Expe-rienced,(5)Perception,and(6)knowledge of Sustainability Issues,Building Sus-tainability Rating Systems and Building Impacts.A survey was conducted on the tenant organizations operating in office buildings located in the city area of *** hypothesized relationship between the tenant organizations’WTP for the VABs and its factors were tested using a series of statistical techniques on the data collected from the *** is found that older tenant organizations tend to have lower WTP for the VABs of improved health and comfort of their ***,tenant organizations also have demand for sustainable buildings mainly due to the positive organizational image that sustainable buildings help to *** addition,it is found that the current building sustainability rating systems are inadequate for communicating the sustainability benefits to building occupants and for achieving building ***,the investigation reveals that the use of sustainable technologies is not as important as how the building is being managed during its operational stage for ensuring building sustainability *** findings from this study are useful for channeling the sustainability efforts of the building industry to more effective areas.

关键词： Sustainable Buildings Intangible Value-added Benefits Willingness-to-pay Tenant Organizations Office Buildings Indoor Environment Quality

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采购及合同授予实务——新加坡建筑行业评论

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工程造价管理 2006年第5期 45-48页

作者： D.Singh Goh Ngan Hong robert l.k.tiong 李岩（翻译）李素蕾（翻译）新加坡南洋科技大学土木与环境工程学院新加坡CPG有限咨询公司环境工程部新加坡南洋科技大学土木与环境工程学院东北财经大学山东理工大学

建设项目通常通过建设工程合同实施，建设工程合同是业主和承包商之间的协议。根据项目本身特点和业主的特定要求，选择一个合适的招标程序和合同形式，确保业主和承包商的利益都得以实现。同时在不存在索赔和反索赔的情况下，满足最终... 详细信息

建设项目通常通过建设工程合同实施，建设工程合同是业主和承包商之间的协议。根据项目本身特点和业主的特定要求，选择一个合适的招标程序和合同形式，确保业主和承包商的利益都得以实现。同时在不存在索赔和反索赔的情况下，满足最终用户的需要。因此选择正确的采购方式和合适的承包商是整个项目成功的关键，否则，建设项目可能会失败。

关键词：建设工程合同采购方式建筑行业新加坡建设项目评论承包商合同形式

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Human endogenous retrovirus type-W and multiple sclerosis–related smoldering neuroinflammation

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Neural Regeneration Research 2025年第3期20卷 813-814页

作者： Joel Gruchot laura Reiche Andrew Chan robert Hoepner Patrick küry Department of Neurology Medical Faculty and University Hospital DüsseldorfHeinrich Heine University DüsseldorfDüsseldorfGermany Department of Neurology InselspitalBern University Hospital and University of BernBernSwitzerland

Introduction to human endogenous retrovirus type-W(HERV-W): Genomic inheritance from the past includes retroviral sequences that have been stably incorporated into our genomes and account for up to 8% of human DNA.

关键词： endogenous inflammation Human

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Climate Change:No Going Back

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China Today 2025年第1期74卷 42-44页

作者： robert WAlkER Beijing Normal University Royal Society of Arts Academy of Social Sciences in the U.k

With a commitment to reduce emissions,and its investment in green technology bringing down global costs,China is emerging as the leader in fighting climate *** knows that our world is getting *** also know *** out po... 详细信息

关键词： investment bringing fighting

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隧道开挖中地质风险评估的敏感性分析（英文）

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中国公路学报 2016年第8期29卷 99-112页

作者：白文琦 tiong l k R 长安大学建筑工程学院西安陕西710061 南洋理工大学土木工程学院新加坡639798

在地下开挖工程进行中,地质风险评估是至关重要却也是最薄弱的环节。由于地下结构的不确定性、复杂性以及结构间多种关联性,对地质结构进行风险评估既困难又耗费成本。在对超大型隧道开挖工程进行风险评估时,为了降低前期准备过程耗费... 详细信息

在地下开挖工程进行中,地质风险评估是至关重要却也是最薄弱的环节。由于地下结构的不确定性、复杂性以及结构间多种关联性,对地质结构进行风险评估既困难又耗费成本。在对超大型隧道开挖工程进行风险评估时,为了降低前期准备过程耗费的时间与成本,风险管理经理更倾向于开挖重复地质断面时将其结构视为相似,并认为时间和成本的变化遵从线性关系。但事实上在对地质结构整体进行风险评估时,各个风险参数的相互依赖性和敏感性是未知的。针对进行地质风险评估时风险参数的敏感性和其会引起的变化,采用Monte Carlo模拟法确定了参与地质风险评估的相关风险参数的敏感性和波动性,例如开挖长度、岩石结构排列以及开挖方法等。采用的地质模型和场景以地质学家提出相关假设和较为常规的地质构造为基础。为了便于整合地质风险评估的各种因素,模拟时将不确定性量化为开挖进尺和成本。通过不同场景的模拟,确定地质风险评估中各个参数的敏感性。研究结果表明:地质结构和开挖进尺皆为独立影响因素,但当在不同的地质结构开挖长度相等时,其排列顺序却对开挖进尺和成本影响不大;在开挖重复地质结构时,开挖进尺和成本的变化遵从非线性关系。研究结果提供了一个对风险进行评估和管理的有效系统,可帮助决策者在管理大型复杂的隧道开挖项目时做出更好的判断。

关键词：隧道工程风险管理地质工程开挖敏感性分析

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Effects of P301l-TAU on post-translational modifications of microtubules in human iPSC-derived cortical neurons and TAU transgenic mice

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Neural Regeneration Research 2025年第8期20卷 2348-2360页

作者： Mohamed Aghyad Al kabbani Christoph köhler Hans Zempel Institute of Human Genetics Faculty of Medicine and University Hospital CologneUniversity of CologneCologneGermany Center for Molecular Medicine Cologne(CMMC) University of CologneCologneGermany Center Anatomy Department ⅡMedical FacultyUniversity of CologneCologneGermany

TAU is a microtubule-associated protein that promotes microtubule assembly and stability in the *** is missorted and aggregated in an array of diseases known as *** are essential for neuronal function and regulated via a complex set of post-translational modifications,changes of which affect microtubule stability and dynamics,microtubule interaction with other proteins and cellular structures,and mediate recruitment of microtubule-severing *** impairment of microtubule dynamics causes neuronal dysfunction,we hypothesize cognitive impairment in human disease to be impacted by impairment of microtubule *** therefore aimed to study the effects of a disease-causing mutation of TAU(P301l)on the levels and localization of microtubule post-translational modifications indicative of microtubule stability and dynamics,to assess whether P301l-TAU causes stability-changing modifications to *** investigate TAU localization,phosphorylation,and effects on tubulin post-translational modifications,we expressed wild-type or P301l-TAU in human MAPT-kO induced pluripotent stem cell-derived neurons(i Neurons)and studied TAU in neurons in the hippocampus of mice transgenic for human P301l-TAU(p R5 mice).Human neurons expressing the longest TAU isoform(2N4R)with the P301l mutation showed increased TAU phosphorylation at the AT8,but not the p-Ser-262 epitope,and increased polyglutamylation and acetylation of microtubules compared with endogenous TAU-expressing neurons.P301l-TAU showed pronounced somatodendritic presence,but also successful axonal enrichment and a similar axodendritic distribution comparable to exogenously expressed 2N4R-wildtype-TAU.P301l-TAU-expressing hippocampal neurons in transgenic mice showed prominent missorting and tauopathy-typical AT8-phosphorylation of TAU and increased polyglutamylation,but reduced acetylation,of microtubules compared with non-transgenic *** sum,P301l-TAU results in changes in micr

关键词： human induced pluripotent stem cell microtubules P301l pR5 mice TAU tauopathy tubulin code

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Novel technique for anastomotic salvage using transanal minimally invasive surgery:A case report

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World Journal of Gastrointestinal Surgery 2019年第5期11卷 271-278页

作者： Oscar A Olavarria robert l kress Shinil k Shah Amit k Agarwal Center for Surgical Trials and Evidence-Based Practice McGovern Medical School at the University of Texas Health Science Center at HoustonHoustonTX 77033United States Department of Surgery McGovern Medical School at the University of Texas Health Science Center HoustonHoustonTX 77033United States

BACkGROUND Anastomotic leak(Al) after low anterior resection(lAR) can be a highly morbid *** incidence of Al ranges from 5% to 20% depending on patient characteristics and the distance of the anastomosis from the anal *** anastomoses and leaks pose technical challenges for endoscopic *** aim of this report was to describe the use of a commercially available laparoscopic energy device through a transanal minimally invasive surgery(TAMIS) port for the management of a symptomatic leak not requiring relaparotomy(grade B) after a lAR with diverting loop *** SUMMARY A TAMIS GelPOINT Path port was inserted into the anus to access the distal *** was achieved with AirSeal insufflation and a 30 degree laparoscope was introduced through a trocar.A ligaSure TM Retractable l-Hook device was then used to perform a septotomy of the chronic sinus tract identified posterior to the *** procedure was then repeated twice in three weeks intervals with ultimate resolution of the chronic leak *** months after serial TAMIS septotomies,barium enema demonstrated a patent anastomosis with no evidence of persistent leak or *** patient subsequently underwent ileostomy reversal and has had no significant postoperative *** TAMIS septotomy with the ligaSure TM Retractable l-Hook is a feasible andeffective,minimally invasive salvage technique for the treatment of grade B *** studies are needed to assess the generalizability and long-term results of this technique.

关键词： Transanal minimally invasive surgery ligasure hook Anastomotic leak low anterior resection Septotomy Case report

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SO(n)-Invariant Special lagrangian Submanifolds of C^(n+1) with Fixed loci

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Chinese Annals of Mathematics,Series B 2006年第1期27卷 95-112页

作者： robert l. BRYANT Dedicated to the memory of Shiing-Shen Chern

let SO（n） act in the standard way on C^n and extend this action in the usual way to C^n＋l = C＋ C^n. It is shown that a nonsingular special lagrangian submanifold l→∪ C^n＋l that is invariant under this SO（n）-action intersects the fixed C→∪ C^n＋1 in a nonsingular real-analytic arc A （which may be empty）. If n 〉 2, then A has no compact component. Conversely, an embedded, noncompact nonsingular real-analytic arc A→∪ C lies in an embedded nonsingular special lagrangian submanifold that is SO（n）-invariant. The same existence result holds for compact A if n =2. nonsingular SO（n）-invariant special lagrangian nonsingular SO（n）-invariant special lagrangian extensions in some open neighborhood of A. If A is connected, there exist n distinct extensions of A such that any embedded extension of A agrees with one of these n The method employed is an analysis of a singular nonlinear PDE and ultimately calls on the work of Gerard and Tahara to prove the existence of the extension.

关键词： Calibrations Special lagrangian submanifolds

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Boundary element method (BEM) applied to the rough surface contact vs. BEM in computational mechanics

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Friction 2019年第4期7卷 359-371页

作者： Yang XU robert l.JACkSON Mechanical Engineering Department Auburn University

In the numerical study of rough surfaces in contact problem, the flexible body beneath the roughness is commonly assumed as a half-space or a half-plane. The surface displacement on the boundary, the displacement components and state of stress inside the half-space can be determined through the convolution of the traction and the corresponding influence function in a closed-form. The influence function is often represented by the Boussinesq-Cerruti solution and the Flamant solution for three-dimensional elasticity and plane strain/stress, respectively. In this study, we rigorously show that any numerical model using the above mentioned half-space solution is a special form of the boundary element method(BEM). The boundary integral equations(BIEs) in the BEM is simplified to the Flamant solution when the domain is strictly a half-plane for the plane strain/stress condition. Similarly, the BIE is degraded to the Boussinesq-Cerruti solution if the domain is strictly a half-space. Therefore, the numerical models utilizing these closed-form influence functions are the special BEM where the domain is a half-space(or a half-plane). This analytical work sheds some light on how to accurately simulate the non-half-space contact problem using the BEM.

关键词： boundary element method rough surface contact half-space half-plane Flamant solution Boussinesq-Cerruti solution

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Hurricane disturbances, tree diversity, and succession in North Carolina Piedmont forests, USA

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Journal of Forestry Research 2019年第1期30卷 219-231页

作者： Weimin Xi robert k.Peet Michael T.lee Dean l.Urban Department of Biology University of North Carolina at Chapel Hill Department of Biological and Health Sciences Texas A & M University-Kingsville The Nicholas School of the Environment Duke University

Windthrow plays a critical role in maintaining species diversity in temperate forests. Do large-scale strong wind events(i.e., tropical cyclones, including hurricanes,typhoons and severe cyclonic storms) increase tree diversity in severely damaged forest areas? Do hurricanes(tropical cyclones that occurs in the Atlantic Ocean and northeastern Pacific Ocean) lead to altered relative abundance of shade-tolerant and shade-intolerant species? Did historic hurricanes alter the succession trajectory of the damaged forests? We used nearly 70-year tree demographic data to assess the effects of two major hurricanes on woody species diversity in Piedmont forests, North Carolina, USA. Species richness(S) and Shannon–Wiener's diversity index(H') were used to evaluate the changes in tree diversity. The changes in composition were assessed with Nonmetric Multidimensional Scaling. The pre-hurricane successional phase can strongly influence both the damage severity and subsequent responses. Although there is often an immediate drop in diversity following a hurricane, understory tree diversity quickly increases to levels that exceed those prior to the disturbance. This leads to an increase in diversity in stands that were substantially damaged. Hurricanes significantly decrease the dominance of shade-intolerant canopy species while increasing preestablished, more shade-tolerant species. We conclude that large, and infrequent hurricanes help to maintain local tree diversity, but also accelerate the increase in dominance of understory species such as red maple and beech.

关键词： Wind disturbance Tree species diversity Plant succession Disturbance-diversity relationship Piedmont forests

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