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国际医学放射学杂志 2024年第3期 375-376页

作者： H.van Voorst j.W.Hoving M.S.Koopman j.D.Daems D.Peerlings E.Buskens 吴小佳

摘要目的如果在CT血管成像（CTA）和平扫CT(NCCT)的标准诊断成像方案之外，还使用CT灌注（CTP），则可以提高疑似急性缺血性卒中（AIS）病人的大血管闭塞（LVO）

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Dissolved organic matter tracers reveal contrasting characteristics across high arsenic aquifers in Cambodia:A fluorescence spectroscopy study

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Geoscience Frontiers 2019年第5期10卷 1653-1667页

作者： Laura A. Richards Dan j. Lapworth Daniel Magnone Daren C. Gooddy Lee Chambers Peter j. Williams Bart E. van Dongen David A. Polya School of Earth and Environmental Sciences and Williamson Research Centre for Molecular Environmental Science The University of ManchesterWilliamson BuildingOxford RoadManchesterM13 9PLUK British Geological Survey Maclean BuildingWallingfordOxfordshireOX10 8BBUK Lancaster Environment Centre Lancaster UniversityLancaster LA1 4YQUK Present address: School of Geography University of LincolnBrayford PoolLincolnLincolnshireLN6 7 TSUK Present address: Department of Civil and Environmental Engineering University of StrathclydeGlasgow G1 1XJUK

Organic matter in the environment is involved in many biogeochemical processes,including the mobilization of geogenic trace elements,such as arsenic,into *** this paper we present the use of fluorescence spectroscopy to characterize the dissolved organic matter (DOM) pool in heavily arsenicaffected groundwaters in Kandal Province,*** fluorescence DOM (fDOM) characteristics between contrasting field areas of differing dominant lithologies were compared and linked to other hydrogeochemical parameters,including arsenic and dissolved methane as well as selected sedimentary ***-corrected fluorescence indices were used to characterize depth profiles and compare field *** fDOM was generally dominated by terrestrial humic and fulvic-like components,with relatively small contributions from microbially-derived,tryptophan-like *** fDOM from sand-dominated sequences typically contained lower tryptophan-like,lower fulvic-like and lower humic-like components,was less bioavailable,and had higher humification index than clay-dominated *** concentrations were strongly correlated with fDOM bioavailability as well as with tryptophan-like components,suggesting that groundwater methane in these arsenic-prone aquifers is likely of biogenic origin.A comparison of fDOM tracers with sedimentary OM tracers is consistent with the hypothesis that external,surface-derived contributions to the aqueous DOM pool are an important control on groundwater hydrogeochemistry.

关键词： Arsenic Fluorescence spectroscopy Organic matter characterization Parallel factor analysis (PARAFAC) Groundwater quality

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Oil quenched malleable iron,the strength of an old material in a “green cast” development and a new future

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China Foundry 2010年第4期7卷 447-455页

作者： Cornelis j.van Ettinger Gieterij.Doesburg B.Ubbinkweg 26981 EC DoesburgThe Netherlands

Malleable iron lost the interest and the development stopped in the turbulent seventies of tremendous developments of new technologies. The personal computer, emission spectrometer, thermal analysis, cold-box core system and automatic vertical moulding were introduced into the foundry industry. Experience shows that these new technologies do not always match up with malleable iron. Solidifciation and mould filling simulation programs are not always capable to handle a low carbon equivalent iron like malleable iron. Recent developments show however by using these new technologies and combined with practical experience, it is possible to increase the casting yield of malleable iron to the same level as ductile iron. The mechanical properties, especially the yield strength of malleable iron according to the standard are equivalent to those of ductile iron, however the yield strength of oil quenched malleable iron is signifciantly higher than that of ductile iron. An extensive investigation is made between ductile iron, air quenched and oil quenched malleable irons based on the properties of more than 350 test bars produced under the same conditions. The results are compared with the existing international standards and discussed. Other properties like fatigue strength and response to surface treatments as induction hardening are also discussed. The costs of malleable iron are reviewed and compared with other ferro alloys. These recent developments in increasing the casting yield, the understanding of the strength, makes malleable iron competitive with ductile iron and cheaper than the first grade of ausferritic ductile iron, or steel qualities. It is possible to design lighter and save weight which is essential in the automotive industry. An example of "green cast" development for typical applications, used in automotive transmissions and engines are shown.

关键词： malleable iron ductile iron oil quenched mechanical properties automotive industry

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Tunable photocycle kinetics of a hybrid bacteriorhodopsin/quantum dot system

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Nano Research 2019年第2期12卷 365-373页

作者： Terianna j. Wax j.rdan A. Greco Shutang Chen Nicole L. Wagner j.ng Zhao robert R. Birge 55 North Eagleville Rd Department of Chemistry University of Connecticut Storrs CT 06269-3060 USA

The inclusion of inorganic nanoparticles in biological environments has led to the creation of hybrid nanosystems that are employed in a variety of applications. One such system includes quantum dots (QDs) coupled with the photoactive protein, bacteriorhodopsin (BR), which has been explored in developing enhanced photovoltaic devices. In this work, we have discovered that the kinetics of the BR photocycle can be manipulated using CdSe/CdS (core/shell) QDs. The photocycle lifetime of protein samples with varying QD amounts were monitored using time-resolved absorption spectroscopy. Concentration-dependent elongations of the bR and M state lifetimes were observed in the kinetic traces, thus suggesting that excitonic coupling occurs between BR and QDs. We propose that the pairing of BR with QDs has the potential to be utilized in protein-based computing applications, specifically for real-time holographic processors, which depend on the temporal dynamics of the bR and M photointermediates.

关键词： bacteriorhodopsin photocycle bionanotechnology photochromism quantum dot hybrid materials

Wild rice research: Advancing plant science and food security

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Molecular Plant 2022年第4期15卷 563-565页

作者： robert j.Henry Queensland Alliance for Agriculture and Food Innovation University of QueenslandBrisbaneQLD 4072Australia ARC Centre of Excellence for Plant Success in Nature and Agriculture University of QueenslandBrisbaneQLD 4072Australia

Rice was domesticated in Asia(Oryza sativa)and Africa(Oryza glaberrima)from Oryza rufipogon and Oryza bathii,*** Oryza genus has a pantropical *** genetic diversity in Oryza provides an extensive gene pool to adapt rice to climate change and address future food *** primary gene pool of domesticated rice includes species that are readily accessible for rice breeding due to ease of crossing,while more distant species are also sources of useful genes that can be recovered with greater difficulty(Figure 1).Advances in genomics and gene editing provide a path for use of this wider *** of Oryza species also offer potential insights into rice biology that may be critical for ongoing rice food security.

关键词： sativa Oryza breeding

The Salt Overly Sensitive （SOS） Pathway： Established and Emerging Roles

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Molecular Plant 2013年第2期6卷 275-286页

作者： Hongtao j. j.sé M. Pardo Giorgia Batelli Michael j. van Oosten Ray A. Bressan Xia Li The State Key Laboratory of Plant Cell and Chromosome Engineering Center of Agricultural Resources Research Institute of Genetics andDevelopmental Biology Chinese Academy of Sciences Shijiazhuang Hebei 050021 PR China Instituto de Recursos Naturales y Agrobiologia Consejo Superior de Investigaciones Cientificas Sevilla-41012 Spain CNR Institute of Plant Genetics (CNR-IGV) Via Universita' i33 80055 Portici Italy Department of Agricultural Engineering and Agronomy University of Naples Federico II Via Universit~ 100 80055 Portici Italy Center for Plant Environmental Stress Physiology Purdue University West Lafayette IN 47907-2010 USA Department Biological Sciences King Abdulaziz University Kingdom of Saudi Arabia

Soil salinity is a growing problem around the world with special relevance in farmlands. The ability to sense and respond to environmental stimuli is among the most fundamental processes that enable plants to survive. At the cellular level, the Salt Overly Sensitive （SOS） signaling pathway that comprises SOS3, SOS2, and SOS1 has been proposed to mediate cellular signaling under salt stress, to maintain ion homeostasis. Less well known is how cellularly heterog- enous organs couple the salt signals to homeostasis maintenance of different types of cells and to appropriate growth of the entire organ and plant. Recent evidence strongly indicates that different regulatory mechanisms are adopted by roots and shoots in response to salt stress. Several reports have stated that, in roots, the SOS proteins may have novel roles in addition to their functions in sodium homeostasis. SOS3 plays a critical role in plastic development of lateral roots through modulation of auxin gradients and maxima in roots under mild salt conditions. The SOS proteins also play a role in the dynamics of cytoskeleton under stress. These results imply a high complexity of the regulatory networks involved in plant response to salinity. This review focuses on the emerging complexity of the SOS signaling and SOS protein functions, and highlights recent understanding on how the SOS proteins contribute to different responses to salt stress besides ion homeostasis.

关键词： auxin ion homeostasis root system architecture salt stress the SOS signaling pathway.

Randomized Trial of Ciclosporin with 2-h Monitoring *** with Trough Monitoring in Liver Transplantation:DELTA Study

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j.urnal of Clinical and Translational Hepatology 2023年第4期11卷 839-849页

作者： Bastian N.Ruij.er Akin Inderson Aad Pvan den Berg Herold j.Metselaar j.roen Dubbeld Maarten E.Tushuizen robert j.Porte Woj.iech Polak Danny van der Helm Marj.lein van Reeven Mar Rodriguez-Girondo Bart van Hoek Department of Gastroenterology and Hepatology LUMC Transplantation CenterLeiden University Medical CenterLeidenThe Netherlands Department of Gastroenterology and Hepatology University Medical Center GroningenGroningenThe Netherlands Department of Gastroenterology and Hepatology Erasmus MC Transplant InstituteErasmus Medical CenterRotterdamThe Netherlands Department of Surgery LUMC Transplantation CenterLeiden University Medical CenterLeidenThe Netherlands Department of Surgery Section HPB Surgery and Liver TransplantationUniversity of GroningenUniversity Medical Center GroningenGroningenThe Netherlands Department of Surgery Division of HPB and Transplant SurgeryErasmus MC Transplant InstituteErasmus Medical CenterRotterdamThe Netherlands Department of Biomedical Data Sciences Leiden University Medical CenterLeidenThe Netherlands.

Background and Aims:Previous trials comparing cyclosporine and tacrolimus after liver transplantation(LT)showed conflicting *** used trough monitoring for cyclosporine(C0),leading to less accurate dosing than with 2-h monitoring(C2).Only one larger trial compared C2 with tacrolimus based on trough level(T0)after LT,with similar treated biopsy-proven acute rej.ction(tBPAR)and graft loss,while a smaller trial had less tBPAR with C2 compared to ***,it is still unclear which calcineurin inhibitor is preferred after *** aimed to demonstrate superior efficacy(tBPAR),tolerability,and safety of C2 or T0 after first ***:Patients after first LT were randomized to C2 or ***,patient-and graft survival,safety and tolerability were the main endpoints,with analysis by Fisher test,Kaplan-Meier survival analysis and log-rank ***:In intention-totreat analysis 84 patients on C2 and 85 on T0 were *** incidence of tBPAR C2 vs.T0 was 17.7%vs.8.4%at 3 months(p=0.104),and 21.9%vs.9.7%at 6 and 12 months(p=0.049).One-year cumulative mortality C2 vs.T0 was 15.5%vs.5.9%(p=0.049)and graft loss 23.8%vs.9.4%(p=0.015).Serum triglyceride and LDL-cholesterol was lower with T0 than with *** of diarrhea in T0 vs,C2 was 64%vs.31%(p≤0.001),with no other differences in safety and ***:In the first year after LT immunosuppression with T0 leads to less tBPAR and better patient-/re-transplant-free survival as compared to C2.

关键词： Adverse effects Ciclosporin Liver transplantation Outcome Randomized controlled trial Rej.ction Survival Renal function Tacrolimus

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Temporal Bone 2010

Spatio-temporal variation in childhood growth in Nigeria:a comparison of aggregation and interpolation

2010年

作者： j.hn I. Lane robert j. Witte

来源：畅想之星图书光盘版（南... 评论

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畅想之星图书光盘版（南通市图书馆镜像）

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International j.urnal of Digital Earth 2017年第11期10卷 1166-1176页

作者： Elise Hellwig robert j.Hij.ans Environmental Science and Policy University of CaliforniaDavisDavisCAUSA

The mean height-for-age Z-score(HAZ)of children under five is an important indicator of the health status of a *** values are frequently aggregated and reported at the national level,potentially obscuring important within-country *** evaluated aggregation and interpolation methods to provide sub-national estimates over space and time,using survey data from Nigeria in 1990,2003,2008,and *** aggregated HAZ values by region and by state,and interpolated the values spatially and spatio-temporally using thin plate *** results were evaluated with cross-validation using the root mean squared error(RMSE)as a measure of goodness of *** HAZ values increased from 1990 to 2013,but values rose more sharply in southern Nigeria than in the *** methods performed better than assuming a constant national *** state-level aggregation,and the spatial and spatio-temporal interpolations had similar RMSE values,but the interpolation methods showed more detailed spatial ***-temporal interpolation produced good results in all conditions,including in years with sparse sampling and when extrapolating to years for which there were no observations.

关键词： Height-for-age health surveys DHS prediction stunting

Forces and energetics of intermittent swimming

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Acta Mechanica Sinica 2017年第4期33卷 725-732页

作者： Daniel Floryan Tyler van Buren Alexander j.Smits Department of Mechanical and Aerospace Engineering Princeton University Princeton NJ 08544 USA

Experiments are reported on intermittent swimming motions. Water tunnel experiments on a nominally two-dimensional pitching foil show that the mean thrust and power scale linearly with the duty cycle, from a value of 0.2 all the way up to continuous motions, indicating that individual bursts of activity in intermittent motions are independent of each other. This conclusion is corroborated by particle image velocimetry（PIV） flow visualizations, which show that the main vortical structures in the wake do not change with duty cycle. The experimental data also demonstrate that intermittent motions are generally energetically advantageous over continuous motions. When metabolic energy losses are taken into account, this conclusion is maintained for metabolic power fractions less than 1.

关键词： intermittent swimming maintained conclusion cycle thrust favorable producing aquatic circles

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