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从ACTION研究的高血压亚组分析结果看长效钙通道阻断剂治疗冠心病的有效性和安全性

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世界核心医学期刊文摘（心脏病学分册） 2005年第5期1卷 8-9页

作者： robert h.fagard

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Prehypertension, hypertension and Associated Cardiovascular Risk Factors among Adult Congolese Urban Dwellers: Results of the Vitaraa Study

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World Journal of Cardiovascular Diseases 2014年第8期4卷 390-398页

作者： Mwasa Pascal Bayauli Jean-Rene M’Buyamba-Kayamba Daniel Lemogoum robert fagard Jean Paul Degaute Mpandamadi Symphorien Ditu Bompeka Francois Lepira Jean-Rene M’Buyamba-Kabangu hypertension Unit/Cardiology Department of Internal MedicineUniversity of Kinshasa HospitalKinshasaThe Democratic Republic of the Congo Division of Endocrinology and Nuclear Medicine Department of Internal MedicineUniversity of Kinshasa HospitalKinshasaThe Democratic Republic of the Congo Erasmus hospital Brussels Free UniversityBrusselsBelgium Division of hypertension and Cardiovascular Rehabilitation University of LeuvenLeuvenBelgium Division of Nephrology Department of Internal MedicineUniversity of Kinshasa HospitalKinshasaThe Democratic Republic of the Congo

Objective: To assess the prevalence of prehypertension and hypertension, their determinants and associated cardiovascular risk factors in Congolese urban dwellers. Methods: From July 2007 to March 2008, we collected information on lifestyle habits, medical history and anthropometric data in 1292 household members of Adoula Quarter, Kinshasa, aged 20 years or more, 731 women (56.6%). We obtained measurements of BP, blood glucose, serum lipids and qualitative proteinuria. We defined blood pressure categories according to JNC7 classification and used logistic regression analyses to assess their independent determinants. We obtained age adjustment of continuous and categorical variables using GLM and Genmod procedures, respectively. Results: Prehypertension was observed in 30.3% of subjects, 34.9% of men and 26.7% of women (P = 0.0045). The prevalence of hypertension amounted to 30.9% with no difference between genders. Participants with prehypertension had average age, BMI and waist circumference intermediate between those with normal BP and hypertensive subjects. Their glucose and lipids levels were similar to those of normotensives. The prevalence of prehypertension amounted to 33% at age 20 - 29 years and decreased to 16.7% at ≥60 years whereas the prevalence of hypertension increased from 11.2% to 71.4%. The rates of diabetes mellitus were similar accross blood pressure catogo- ries whilst prevalences of overweight/obesity, abdominal adiposity, dyslipidemia and metabolic syndrome significatively increased (P = 0.05 or less). Among participants with prehypertension, 73% had two or more additional cardiovascular risk factors. In the logistic model the probability of prehypertension was higher in men (OR: 1.429;95% CI: 1.099 - 1.857) and participants with overweight/obesity (OR: 1.666;1.146 - 2.422), lower in participants aged ≥ 55 years (0.427;0.267 - 0.683) and those with high fruit intake (0.691;0.488 - 0.977). The probability of hypertension was higher in particip

关键词： Prehypertension hypertension Cardiovascular Risk Factors Africans

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