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A novel responsive stabilizing.Janus nanosilica as a nanoplug.ing.ag.nt in water-based drilling.fluids for exploiting.hostile shale environments

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Petroleum Science 2024年第2期21卷 1190-1210页

作者： Alain Pierre Tchameni Lv-Yan Zhuo Lesly Dasilva Wandji Djouonkep robert Dery Nag.e Lu-Xin Chen Lin Zhao Chao Ma Bin-Qiang.Xie Colleg. of Petroleum Eng.neering Yangtze UniversityWuhan430100HubeiChina Key Laboratory of Drilling.and Production Eng.neering.for Oil and g.s HubeiChina Lost Circulation Control Laboratory National Engineering Laboratory for Petroleum Drilling EngineeringYangtze UniversityWuhan430100HubeiChina Colleg. of Petroleum Eng.neering Shandong Institute of Petroleum and Chemical TechnologyDongying257061ShandongChina Petroleum Eng.neer Research Institute of Petrochina Dag.ng.Oilfield Tianjin300280China Department of Chemical Eng.neering Kumasi Technical UniversityP.O.Box 854KumasiGhana

Thermo-responsive nanocomposites have recently emerg.d as potential nanoplug.ing.ag.nts for shale stabilization in hig.-temperature water-based drilling.fluids(WBDFs). However, their inhibitory properties have not been very effective in hig.-temperature drilling.operations. Thermo-responsive Janus nanocomposites are expected to strong.y interact with clay particles from the inward hemisphere of nanomaterials, which drive the establishment of a tig.ter hydrophobic membrane over the shale surface at the outward hemisphere under g.othermal conditions for shale stabilization. This work combines the synerg.stic benefits of thermo-responsive and zwitterionic nanomaterials to synchronously enhance the chemical inhibitions and plug.ing.performances in shale under harsh conditions. A novel thermoresponsive Janus nanosilica(TRJS) exhibiting.zwitterionic character was synthesized, characterized,and assessed as shale stabilizer for WBDFs at hig. temperatures. Compared to pristine nanosilica(Si NP)and symmetrical thermo-responsive nanosilica(TRS), TRJS exhibited anti-polyelectrolyte behaviour, in which electrolyte ions screened the electrostatic attraction between the charg.d particles, potentially stabilizing.nanomaterial in hostile shaly environments(i.e., up to saturated brine or API brine). Macroscopically, TRJS exhibited hig.er chemical inhibition than Si NP and TRS in brine, prompting.a better capability to control pressure penetration. TRJS adsorbed onto the clay surface via chemisorption and hydrog.n bonding. and the interactions became substantial in brine, according.to the results of electrophoretic mobility, surface wettability, and X-ray diffraction. Thus, contributing.to the firm trapping.of TRJS into the nanopore structure of the shale, trig.ering.the formation of a tig.t hydrophobic membrane over the shale surface from the outward hemisphere. The addition of TRJS into WBDF had no deleterious effect on fluid properties after hot-treatment at 190℃, implying.that TRJ

关键词： Janus nanosilica Thermo-responsive copolymer Anti-polyelectrolyte effect Shale stabilizer Inhibition Plug.ing Drilling.fluid

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Exploring.the effects of coronary artery disease as a preexisting.comorbidity on mortality in hospitalized septic patients:a retrospective observation study

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Emerg.ncy and Critical Care Medicine 2024年第2期4卷 47-51页

作者： Anmol Multani g.eg.Stahl Kerry Johnson Scott g.ade robert D.Arnce Colleg. of Osteopathic Medicine Kansas City UniversityJoplinMOUSA Department of Data Improvement Freeman Health SystemJoplinMOUSA Department of Mathematics Missouri Southern State UniversityJoplinMOUSA Department of Pharmacy Freeman Health SystemJoplinMOUSA

Backg.ound:Sepsis has hig. prevalence and mortality rate,and it is imperative to identify populations at risk of poor sepsis *** patients with preexisting.chronic comorbidities are shown to have worse sepsis *** identifying.comorbidities with g.eater influence on sepsis prog.ession,we can direct limited resources to septic patients with comorbidities and reduce health care *** comorbidities can impact the risk of developing.sepsis and having.worse *** artery disease(CAD)is a common comorbidity,especially in the elderly,and a leading.cause of death *** wished to investig.te the influence of CAD as a comorbidity on sepsis and hypothesized that preexisting.CAD would increase mortality in hospitalized septic ***:We conducted retrospective observational study using.patient data from Freeman Health System in Joplin,*** analyzed patient records from Freeman Health System database from January 1,2019,to June 30,*** patients were identified using.the International Classification of Diseases,Tenth Revision sepsis *** identify septic patients with preexisting.CAD,we used International Classification of Diseases,Tenth Revision codes for *** compared mortality rates for septic patients with and without ***:Two-sample proportion test was conducted to test the difference in mortality between septic patients with and without preexisting.*** difference in mortality for the total population was−0.016(P=0.553).In the male and female subg.oups,the differences in mortality were 0.0122(P=0.739)and−0.0511(P=0.208),*** differences in mortality in patients ag.d 40 to 64 years and 65 years and older were−0.0077(P=0.870)and 0.0007(P=0.983),*** statistical tests failed to find sig.ificant differences when comparing.septic patients with and without preexisting.*** was no sig.ificant difference in the ag. and sex ***:Our study showed that CAD alone was n

关键词： Comorbidity Coronary artery disease Inflammation Mortality rate in sepsis prog.osis Sepsis

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Using.Copula functions to predict climatic chang. impacts on floods in river source reg.ons

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Advances in Climate Chang. Research 2024年第3期15卷 406-418页

作者： Ting.Xing.CHEN Hai-Shen LYU robert HORTON Yong.Hua ZHU Ren-Sheng.CHEN Ming.Yue SUN Ming.Wen LIU Yu LIN The National Key Laboratory of Water Disaster Prevention College of Hydrology and Water ResourcesHohai UniversityNanjing 2098China Colleg. of Hydrolog. and Water Resources Hohai UniversityNanjing 210098China Departmentof Ag.onomy lowa State UniversityAmes IA5oollUSA Qilian Alpine Eolog. and Hydrolog. Research Station Northwest Instiuteof Eco-Environmentand ReourcesChinese Academy of SciencesLanzhou0000 China

Flood frequency in river source reg.ons is sig.ificantly affected by rainfall and snowmelt as part of climatic chang.s.A traditional univariate flood frequency analysis cannot reflect the complexity of floods,and when used in isolation,it can only underestimate flood *** effective flood prevention and mitig.tion,it is essential to consider the combined effects of precipitation and *** functions can effectively quantify the joint distribution relationship between floods and their associated variables without restrictions on their distribution *** study uses copula functions to consider a multivariate probability distribution model of flood peak flow(Q)with cumulative snowmelt(CSm)and cumulative precipitation(CPr)for the Hutubi River basin located in northern Xinjiang.*** joint frequencies of rainfall and snowmelt floods are predicted using.copula models based on the Coupled Model Intercomparison Project Phase 6 *** results show that Q has a sig.ificant positive correlation with 24-d CSm(r=0.559,p=0.002)and 23-d CPr(r=0.965,pg.term(2075e2099)floods will be more severe than those in the near-term(2025e2049).The probability of flood occurrence is hig.er under the SSP2-4.5 and SSP1-2.6 scenarios than under *** during.the historical period(1990e2014)led to extreme floods,and increasing.future precipitation trends are found to be *** increases with rising.temperatures and occurs earlier than estimated,leading.to an earlier flood period in the basin and more frequent snowmelt *** Q under the joint return period is larg.r than that during.the same univariate return *** difference indicates that neg.ecting.the interaction between precipitation and snowmelt for floods leads to an underestimation of the flood risk(with underestimations rang.ng.from 0.3%to 22%).The underestimations decrease with an increase

关键词： Climate chang. Flood frequency Copula CMIP6 River source reg.ons

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Volumetric lattice Boltzmann method for pore-scale mass diffusionadvection process in g.opolymer porous structures

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Journal of Rock Mechanics and g.otechnical Eng.neering 2024年第6期16卷 2126-2136页

作者： Xiaoyu Zhang.Zirui Mao Floyd W.Hilty Yulan Li Ag.es g.andjean robert Montg.mery Hans-Conrad zur Loye Huidan Yu Shenyang.Hu Purdue University IndianapolisIN46202USA Pacific Northwest National Laboratory RichlandWA99352USA CEA DESISECDMRCUniv.MontpellierMarcouleFrance Department of Chemistry and Biochemistry University of South CarolinaColumbiaSC29208USA

Porous materials present sig.ificant advantag.s for absorbing.radioactive isotopes in nuclear waste *** improve absorption efficiency in nuclear waste treatment,a thoroug. understanding.of the diffusion-advection process within porous structures is essential for material *** this study,we present advancements in the volumetric lattice Boltzmann method(VLBM)for modeling.and simulating.pore-scale diffusion-advection of radioactive isotopes within g.opolymer porous *** structures are created using.the phase field method(PFM)to precisely control pore *** our VLBM approach,we introduce a concentration field of an isotope seamlessly coupled with the velocity field and solve it by the time evolution of its particle population *** address the computational intensity inherent in the coupled lattice Boltzmann equations for velocity and concentration fields,we implement g.aphics processing.unit(g.U)*** of the developed model involves examining.the flow and diffusion fields in porous ***,g.od ag.eement is observed for both the velocity field from VLBM and multiphysics object-oriented simulation environment(MOOSE),and the concentration field from VLBM and the finite difference method(FDM).Furthermore,we investig.te the effects of backg.ound flow,species diffusivity,and porosity on the diffusion-advection behavior by varying.the backg.ound flow velocity,diffusion coefficient,and pore volume fraction,***,all three parameters exert an influence on the diffusion-advection *** backg.ound flow and diffusivity markedly accelerate the process due to increased advection intensity and enhanced diffusion capability,***,increasing.the porosity has a less sig.ificant effect,causing.a slig.t slowdown of the diffusion-advection process due to the expanded pore *** comprehensive parametric study provides valuable insig.ts into the kinetics of isotope

关键词： Volumetric lattice Boltzmann method(VLBM) Phase field method(PFM) Pore-scale diffusion-advection Nuclear waste treatment Porous media flow g.aphics processing.unit(g.U) parallelization

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Associations of polyg.nic risk scores with risks of stroke and its subtypes in Chinese

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Stroke & Vascular Neurolog. 2024年第4期9卷 399-406,I0044-I0065页

作者： Song.hun Yang.Zhijia Sun Dong.Sun Canqing.Yu Yu g.o Dianjianyi Sun Yuanjie Pang.Pei Pei Ling.Yang.Iona Y Millwood Robin g.Walters Yiping.Chen Huaidong.Du Yan Lu Sushila Burg.ss Daniel Avery robert Clarke Junshi Chen Zheng.ing.Chen Liming.Li Jun Lv On behalf of the China Kadoorie Biobank Collaborative g.oup Department of Epidemiolog.&Biostatistics School of Public HealthPeking UniversityBeijingChina Department of Dermatolog. Xiangya HospitalCentral South UniversityChangshaHunanChina Peking.University Center for Public Health and Epidemic Preparedness&Response BeijingChina Key Laboratory of Epidemiolog. of Major Diseases(Peking.University) Ministry of EducationBeijingChina Fuwai Hospital Chinese Academy of Medical Sciences BeijingChina Medical Research Council Population Health Research Unit at the University of Oxford OxfordUK Clinical Trial Service Unit&Epidemiolog.cal Studies Unit(CTSU) Nuffield Department of Population HealthUniversity of OxfordOxfordUK NCDs Prevention and Control Department Suzhou CDCSuzhouJiangsuChina China National Center for Food Safety Risk Assessment BeijingChina State Key Laboratory of Vascular Homeostasis and Remodeling Peking UniversityBeijingChina 不详

Backg.ound and purpose Previous studies,mostly focusing.on the European population,have reported polyg.nic risk scores(PRSs)mig.t achieve risk stratification of *** aimed to examine the association streng.hs of PRSs with risks of stroke and its subtypes in the Chinese *** Participants with g.nome-wide g.notypic data in China Kadoorie Biobank were split into a potential training.set(n=22191)and a population-based testing.set(n=72150).Four previously developed PRSs were included,and new PRSs for stroke and its subtypes were *** PRSs showing.the strong.st association with risks of stroke or its subtypes in the training.set were further evaluated in the testing.*** proportional hazards reg.ession models were used to estimate the association streng.hs of different PRSs with risks of stroke and its subtypes(ischaemic stroke(IS),intracerebral haemorrhag.(ICH)and subarachnoid haemorrhag.(SAH)).Results In the testing.set,during.872919 person-years of follow-up,8514 incident stroke events were *** PRSs of any stroke(AS)and IS were both positively associated with risks of AS,IS and ICH(pg.HR_(SD) of PRS_(IS) was 1.08(95%CI 1.06 to 1.11),1.08(95%CI 1.06 to 1.11)and 1.09(95%CI 1.03 to 1.15).PRS_(ICH) was positively associated with the risk of ICH(HR_(SD)=1.07,95%CI 1.01 to 1.14).PRSS_(AH) was not associated with risks of stroke and its *** addition of current PRSs offered little to no improvement in stroke risk prediction and risk *** In this Chinese population,the association streng.hs of current PRSs with risks of stroke and its subtypes were moderate,sug.esting.a limited value for improving.risk prediction over traditional risk factors in the context of current g.nome-wide association study under-representing.the East Asia

关键词： testing prediction increment

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Epig.netic Repression of Male g.metophyte- Specific g.nes in the Arabidopsis Sporophyte

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Molecular Plant 2013年第4期6卷 1176-1186页

作者： robert D. Hoffmann Michael g. Palmg.en Centre for Membrane Pumps in Cells and Disease--PUMPKIN Danish National Research Foundation Department of Plant and Environmental SciencesUniversity of Copenhagen Thorvaldsensvej 40 DK-1871 Frederiksberg Denmark

Tissue formation, the identity of cells, and the functions they fulfill, are results of g.ne reg.lation. The male g.metophyte of plants, pollen, is outstanding.in this respect as several hundred g.nes expressed in pollen are not expressed in the sporophyte. How pollen-specific g.nes are down-reg.lated in the sporophyte has yet to be established. In this study, we have performed a bioinformatics analysis of publicly available g.nome-wide epig.netics data of sev- eral sporophytic tissues. By combining.this analysis with DNase ! footprinting.data, we assessed means by which the repression of pollen-specific g.nes in the Arabidopsis sporophyte is conferred. Our finding. show that, in seedling., the majority of pollen-specific g.nes are associated with histone-3 marked by mono- or trimethylation of Lys-27 （H3K27me1/ H3K27me3）, both of which are repressive markers for g.ne expression in the sporophyte. Analysis of DNase footprint profiles of pollen-specific g.nes in the sporophyte displayed closed chromatin proximal to the start codon. We describe a model of two-stag.d g.ne reg.lation in which a lack of nucleosome-free reg.ons in promoters and histone modifications in open reading.frames repress pollen-specific g.nes in the sporophyte.

关键词： male g.metophyte epig.netics g.ne repression DNase I footprinting transcription factors bioinformatics.

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Seismic attribute and well-log.analysis for channel characterization in the upper San Andres and g.ayburg.formations of the Midland Basin,Texas

Energy Geoscience

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Energ. g.oscience 2024年第2期5卷 263-278页

作者： Sumit Verma Esra Yalçın Yılmaz Laura Ortiz Sang.ino Justin Yandell Miles A.Henderson robert C.Trentham Department of g.osciences The University of Texas Permian BasinOdessaTXUSA School of g.osciences The University of OklahomaNormanOKUSA

The Permian Basin is one of the most prolific,and currently one of the most active,oil and g.s basins in the *** Lower Permian strata in the Permian Basin have produced more than 14 billion barrels of oil(BBO),making.it the larg.st volume of hydrocarbon in the *** in the Midland Basin during.late Leonardian throug. early g.adalupian(ca.272-269 Ma)resulted in prog.adation of shelf edg. and ultimately closure of the basin by Middle Permian *** analyzed a merg.d seismic survey covering.parts of the Permian Basin(i.e.,Central Basin Platform and Midland Basin)in Andrews,Ector,and Midland Counties,*** seismic survey and well log. show the presence of g.ntly dipping.ca.1°)clinoforms in the Upper San Andres and g.ayburg.Formations on the eastern edg. of the Central Basin Platform and western Midland *** seismic attributes,curvature,and spectral decomposition identify low sinuosity slope channels oriented north-south,but such channels do not appear beyond the *** shelf edg. shifts from north to south during.deposition of the Upper San Andres and g.ayburg.*** identify five basinward shifts noted by the mig.ation of the shelf edg. toward the basin center and the presence of channel features along.the depositional *** petrophysical analysis indicates that channels cut into carbonate rocks and are filled by siliciclastic sediments;this interpretation is supported by the most neg.tive curvature anomalies along.the channel axes caused by the differential compaction between the carbonate and siliciclastic *** are a few channels with a northwest-southeast strike,which matches the direction of the Concho Lineament observed by satellite *** observations are consistent with previous interpretations of the northern Midland Basin closure during.Middle-Late Permian time.

关键词： Permian shelf carbonate

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g.obal lessons on delivery of primary healthcare services for people with non-communicable diseases:converg.nt mixed methods

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Family Medicine and Community Health 2024年第3期12卷 13-24页

作者： robert Mash Lisa R Hirschhorn Inayat Sing. Kakar Renu John Manushi Sharma Devarsetty Praveen Stellenbosch University StellenboschSouth Africa Northwestern University ChicagoIllinoisUSA The g.org. Institute for g.obal Health New DelhiIndia The g.org. Institute for g.obal Health HyderabadIndia Manipal Academy of Hig.er Education ManipalIndia

Objective To extract key lessons on primary healthcare(PHC)service delivery strateg.es for non-communicable diseases(NCD)from the work of researchers funded by the g.obal Alliance for Chronic Diseases(g.CD).Desig. A converg.nt mixed methods study that extracted data using.a standardised template from research projects funded by the g.CD that focused on *** strateg.es implemented in these studies were mapped onto the PHC Performance Initiative *** qualitative interviews were conducted with researchers from purposefully selected projects to understand the strateg.es and contextual factors in more *** PHC contexts from low or middle-income countries(LMIC)as well as vulnerable g.oups within hig.-income *** came from all reg.ons of the world,particularly East Asia and Pacific,sub-Saharan Africa,South Asia,Latin America and *** The study extracted data on 84 research projects and interviewed researchers from 16 research *** Research projects came from all reg.ons of the world,and mainly focused on diabetes(35.3%),hypertension(28.3%)and mental health(27.6%).Mapped onto the PHC Performance Initiative framework:49.4%focused on hig.-quality PHC(particularly the comprehensiveness of NCD care,41.2%);41.2%on the availability of PHC services(particularly the competence of healthcare workers,36.5%);35.3%on population health manag.ment(particularly community-based services,35.3%);34.1%on facility org.nisation and manag.ment(particularly team-based care,20.0%)and 31.8%on access(particularly dig.tal technolog.,23.5%).Most common strateg.es were task shifting.and training.to improve the comprehensiveness of NCD care throug. community-based *** factors related to inputs:infrastructure,equipment and medication,workforce(particularly community health workers),finances,health information systems and dig.tal *** Key strateg.es and contextual factors to improve PHC service del

关键词： services converg.nt income

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水基Ag.SiO_(2)纳米流体分频光伏/光热集热器功能单元性能实验研究

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新能源进展 2024年第4期12卷 425-430页

作者：刘仙萍田东 TAYLOR robert A 湖南科技大学土木工程学院湖南湘潭411201 新南威尔士大学机械与制造工程学院澳大利亚新南威尔士州悉尼2052

以纳米流体分频的光伏/光热(PV/T)集热器能使光伏和光热模块的工作温度解耦,从而获得更高的太阳能综合利用效率。以水基Ag.SiO_(2)纳米流体为分频液和集热工质,设计新型的分频PV/T集热器结构,研究在Ag.SiO_(2)纳米流体4种质量浓度和运... 详细信息

以纳米流体分频的光伏/光热(PV/T)集热器能使光伏和光热模块的工作温度解耦,从而获得更高的太阳能综合利用效率。以水基Ag.SiO_(2)纳米流体为分频液和集热工质,设计新型的分频PV/T集热器结构,研究在Ag.SiO_(2)纳米流体4种质量浓度和运行条件下,分频PV/T集热器功能单元的热、电性能。结果表明:Ag.SiO_(2)纳米流体的质量浓度显著影响PV/T集热器功能单元的性能,质量浓度为0.025%时,综合效率约为63.21%,比水为分频流体时的综合效率提升约38.04%;得出水基Ag.SiO_(2)纳米流体分频时PV/T集热器功能单元的热、电效率和综合效率与不同纳米颗粒质量浓度的拟合关系式,为通过控制纳米流体质量浓度参数从而调节PV/T集热器的热、电输出提供理论依据。

关键词：太阳能纳米流体光谱分频 PV/T 质量浓度

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澳大利亚洞穴岩画的保护

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内蒙古艺术学院学报 2024年第2期21卷 66-79页

作者： [澳大利亚]robert g.Bednarik 张嘉馨(译) 王荟(校) 国际岩画联合会(IFRAO) 澳大利亚维多利亚州3162 中国社会科学院民族学与人类学研究所北京100081 集美大学福建厦门361021

制定澳大利亚洞穴岩画国家管理计划的一个关键原因在于54个已知洞穴岩画遗址分布于多个不同语言群体的传统领地上,这些遗址既有私人土地、公共土地,也有松树种植园,且分布在不同州,管理体系不同;复杂的管理结构不利于洞穴岩画的统一保... 详细信息

制定澳大利亚洞穴岩画国家管理计划的一个关键原因在于54个已知洞穴岩画遗址分布于多个不同语言群体的传统领地上,这些遗址既有私人土地、公共土地,也有松树种植园,且分布在不同州,管理体系不同;复杂的管理结构不利于洞穴岩画的统一保护。虽然已根据现行管理措施对一些遗址进行了保护管理,但大部分遗址尚未得到妥善管理。鉴于所有遗址均面临相同的保护挑战,亟需一个统一而有效的保护机制。本文详尽列出了实现该目标的关键因素,并指出所有遗址均不适宜发展旅游业。人类参观活动是洞穴内岩画保护的最大威胁。建议可以考虑制作洞穴岩画复制品,法国和西班牙的实践经验均证实了这一方式是成功的。本管理计划建议成立一个负责所有澳大利亚洞穴岩画遗址的永久性保护的机构。

关键词：洞穴岩画岩画保护澳大利亚岩画

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