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Laser-induced graphitization of a forest-based ink for use in flexible and printed electronics

npj Flexible Electronics 2020年第1期4卷 149-158页

作者： Jesper Edberg robert brooke Omid Hosseinaei Andreas Fall Kosala Wijeratne Mats Sandberg RISE Bio-and Organic Electronics Bredgatan 3360221NorrköpingSweden RISE Bioeconomy Drottning Kristinas väg 6111428StockholmSweden

Laser-induced graphitization(LIG)is a method of converting a carbon-rich precursor into a highly conductive graphite-like carbon by laser *** method has shown great promise as a versatile and low-cost patterning *** we show for the first time how an ink based on cellulose and lignin can be patterned using screen printing followed by laser *** printing is one of the most commonly used manufacturing techniques of printed electronics,making this approach compatible with existing processing of various *** use of forest-based materials opens the possibility of producing green and sustainable ***-patterning of the ink enables carbon patterns without residual precursor between the *** investigated the effect of the ink composition,laser parameters,and additives on the conductivity and structure of the resulting carbon and could achieve low sheet resistance of 3.8Ωsq^(−1) and a high degree of *** demonstrated that the process is compatible with printed electronics and finally manufactured a humidity sensor which uses lignin as the sensing layer and graphitized lignin as the electrodes.

关键词： forest printing electronics

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Spray-coated paper supercapacitors

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npj Flexible Electronics 2020年第1期4卷 142-148页

作者： Mehmet Girayhan Say robert brooke Jesper Edberg Andrea Grimoldi Dagmawi Belaineh Isak Engquist Magnus Berggren Laboratory of Organic Electronics Department of Science and TechnologyLinköping UniversitySE-60174NorrköpingSweden RISE Research Institutes of Sweden Bio-and Organic ElectronicsBredgatan 35SE-60221NorrköpingSweden Wallenberg Wood Science Center ITNLinköping UniversitySE-60174NorrköpingSweden

The increasing demands to further electrify and digitalize our society set demands for a green electrical energy storage technology that can be scaled between very small,and heavily distributed electrical energy sources,to very large *** technology must be compatible with fast-throughput,large-volume and low-cost fabrication processes,such as using printing and coating ***,we demonstrate a sequential production protocol to fabricate supercapacitors including electrodes based on cellulose nanofibrils(CNF)and the conducting polymer PEDOT:*** and lightweight paper electrodes,carbon adhesion layers and the gel electrolyte are fabricated using spray coating,screen printing,and bar coating,*** all solid-state supercapacitors are flexible,mechanically robust and exhibit a low equivalent series resistance(0.22Ω),thus resulting in a high power density(∼104 W/kg)energy *** supercapacitors are combined and connected to a power management circuit to demonstrate a smart packaging *** work shows that operational and embedded supercapacitors can be manufactured in a manner to allow for the integration with,for instance smart packaging solutions,thus enabling powered,active internet-of-things(IoT)devices in a highly distributed application.

关键词： coating printing electrolyte

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Benefits of the use of blood conservation in scoliosis surgery

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World Journal of Orthopedics 2016年第12期7卷 808-813页

作者： Peter R Loughenbury Lyeanda Berry Ben T brooke Abhay S Rao robert A Dunsmuir Peter A Millner Department of Neurosciences Leeds General Infirmary

AIM To investigate whether autologous blood transfusion(ABT) drains and intra-operative cell salvage reduced donor blood transfusion requirements during scoliosis *** Retrospective data collection on transfusion requirements of patients undergoing scoliosis surgery is between January 2006 and March 2010. There were three distinct phases of transfusion practice over this time: Group A received "traditional treatment" with allogeneic red cell transfusion(ARCT) in response to an intra- or postoperative anaemia(Hb < 8 g/d L or a symptomatic anaemia); Group B received intra-operative cell salvage in addition to "traditional treatment". In group C,ABT wound drains were used together with both intra-operative cell salvage and "traditional treatment".RESULTS Data from 97 procedures on 77 patients,there was no difference in mean preoperative haemoglobin levels between the groups(A: 13.1 g/d L; B: 13.49 g/d L; C: 13.66 g/d L). Allogeneic red cell transfusion was required for 22 of the 37 procedures(59%) in group A,17 of 30(57%) in group B and 16 of 30(53%) in group C. There was an overall 6% reduction in the proportion of patients requiring an ARCT between groups A and C but this was not statistically significant(χ2 = 0.398). Patientsin group C received fewer units(mean 2.19) than group B(mean 2.94)(P = 0.984) and significantly fewer than those in group A(mean 3.82)(P = 0.0322). Mean length of inpatient stay was lower in group C(8.65 d) than in groups B(12.83) or A(12.62).CONCLUSION When used alongside measures to minimise blood loss during surgery,ABT drains and intra-operative cell salvage leads to a reduced need for donor blood transfusion in patients undergoing scoliosis surgery.

关键词： Blood conservation Scoliosis Autologous blood Cell salvage Transfusion

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Fisheries Impacts on Food Supplies to Seabirds

Fisheries Impacts on Food Supplies to Seabirds

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23rd International Ornithological Congress

作者： Lisa T.Ballance Michaelde L.brooke robert W.Furness robert L.Pitman Southwest Fisheries Science Center La Jolla Box 271 CA 92038 USA Dept. Zoology Univ. Cambridge Cambridge CB2 3EJ UK Dept. Zoology Univ. Glasgow Glasgow G12 8QQ UK Southwest Fisheries Science Center La Jolla Box 271 CA 92038 USA

＜正＞ Seabirds take prey that might otherwise be harvested by fishers, and fisheries impact on seabird food supply. We compare, at a global level, the amount of prey taken by fishers and seabirds by using knowledge of seabird global populations and available metabolic equations. The take by seabird and fisher is of the same order of magnitude. However, this global conclusion masks distinct regional differences in bird-fisheries interactions, illustrated with case studies. Tropical fisheries take a substantial biomass of large predatory fishes that dwarfs

关键词： seabirds fisheries tuna discards

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Assessing Performance and Method Transfer of Monoclonal Antibody and Peptide Bioseparation Methods using a novel Biocompatible uhplc system

Assessing Performance and Method Transfer of Monoclonal Anti...

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第六届生物技术药物理化特性分析与质量研究技术研讨会

作者： brooke M.Koshel Ximo Zhang robert Birdsall Corey Reed Stephan Koza Zhimin Li Paula Hong Waters Corporation

＜正＞Introduction The inherent complexity of biotherapeutic drugs requires more analytical methods,and methods capable of handling significant molecular complexity and *** date,many of the methods used in development and quality control laboratories remain *** this may be sufficient in some cases,there are notable advantages for updating legacy systems and

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吉西他滨治疗胰腺癌的药效相关的遗传变异

吉西他滨治疗胰腺癌的药效相关的遗传变异

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全国肿瘤流行病学和肿瘤病因学学术会议

作者：李亮 Gregory Jenkins Erin E.Carlson brooke L.Fridley William R.Bamlet Gloria M.Petersen robert R.McWilliams Liewei Wang 中国医学科学院医药生物技术研究所肿瘤室

研究背景:胰腺癌是一种以吉西他滨为一线治疗药物的迅速致命的恶性疾病。因此,为更好地发挥吉西他滨治疗胰腺癌的药效,我们进行了基因型与表型的关联研究,以筛查预测吉西他滨疗效的生物标志物。方法:我们根据之前利用正常人淋巴母细胞...

研究背景:胰腺癌是一种以吉西他滨为一线治疗药物的迅速致命的恶性疾病。因此,为更好地发挥吉西他滨治疗胰腺癌的药效,我们进行了基因型与表型的关联研究,以筛查预测吉西他滨疗效的生物标志物。方法:我们根据之前利用正常人淋巴母细胞模型系统的GWAS分析结果 ,选取与吉西他滨细胞毒性最相关的200个单核苷酸多态性（SNP）,同时获取经/或不使用吉西他滨联合治疗的400例胰腺癌患者样本,进行Cox比例风险模型分析与患者总生存期（OS）的相关性:进而通过SNP基因型与吉西他滨相互作用分析,确定与吉西他滨作用相关的SNP对患者总生存期（OS）的影响。并通过Imputation分析与OS相关SNPs的200KB上下游区域中SNP对OS的影响。此外,我们还利用其它独立的537例胰腺癌患者的DNA样本,采用TaqMan探针法验证重复候选SNPs。最后,用siRNA干扰候选基因表达水平后,在体外观察吉西他滨细胞毒性,进行实验功能验证。结果:我们利用400例患者样本发现位于染色体1,3,9,和20的4个SNP位点与经吉西他滨治疗的患者OS明显相关（P＜0.01）,以及估算分析获得的4个SNP也呈现相似的相关性。并利用537例其他样本验证得到两基因中的两个估算SNP与吉西他滨治疗后患者的OS呈相关趋势。其中XXX表达水平下降能够明显降低胰腺癌细胞对吉西他滨作用的敏感性。结论:我们筛选确定了4个位于不同区域的SNP可能与吉西他滨暴露后胰腺患者的OS相关。基因XXX可能影响患者个体对吉西他滨的药物反应的差异。这些结果可能有助于我们寻找恰当的药效预测性生物标志物以更好地发挥吉西他滨治疗胰腺癌的药效。

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烧伤病人的补液(三)

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右江医学 1988年第4期 187-189页

作者： robert H Demling,M.D 梁柯

蛋白输注补充蛋白质已成为烧伤早期治疗方案的一个重要组成部分。1952年提倡的 Evans 公式,为头24小时内用胶体和乳酸钠林格氏液各1ml/kg/1%TBSA。很明显,这公式与其说是根据科学测定,还不如说是根据估计值。然而,这一公式的应用取得相... 详细信息

蛋白输注补充蛋白质已成为烧伤早期治疗方案的一个重要组成部分。1952年提倡的 Evans 公式,为头24小时内用胶体和乳酸钠林格氏液各1ml/kg/1%TBSA。很明显,这公式与其说是根据科学测定,还不如说是根据估计值。然而,这一公式的应用取得相当大的成功,提示有某种价值。不久后介绍的brooke 公式,在头24小时内用0.5ml/kg/1%TBSA 的胶体和1.5ml/kg/1%TBSA 的乳酸钠林格氏液。Moore 的烧伤估算法同样用大量胶体。

关键词：烧伤病人蛋白质低分子葡聚糖补液晶体液胶体渗透压乳酸钠林格氏液输注白蛋白溶液组织水肿血容量 TBSA

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