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Storylines of family medicine Ⅹ:standing up for diversity,equity and inclusion

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Family Medicine and Community Health 2024年第S3期12卷 89-98页

作者： William b.Ventres Leslie A Stone Wayne W b.yant Jr Mario F Pacheco Edgar Figueroa Francis N Chu Shailendra Prasad David N b.ane Na'amah Razon Ranit Mishori robert L Ferrer Garrett S Kneese Family and Preventive Medicine University of Arkansas for Medical Sciences College of MedicineLittle RockArkansasUSA Family and Community Medicine University of New Mexico School of MedicineAlbuquerqueNew MexicoUSA Medicine Weill Cornell Medical CollegeNew YorkNew YorkUSA San Jose Family Medicine Residency Kaiser PermanenteSan JoseCaliforniaUSA Family Medicine and Community Health University of Minnesota Medical School—Twin Cities CampusMinneapolisMinnesotaUSA School of Health and Wellb.ing University of GlasgowGlasgowUK Family and Community Medicine University of CaliforniaDavisSacramentoCaliforniaUSA Family Medicine Georgetown University School of MedicineWashingtonDistrict of ColumbiaUSA Family and Community Medicine UT Health San Antonio Long School of MedicineSan AntonioTexasUSA UC San Diego Family Medicine Residency Program San DiegoCaliforniaUSA

Storylines of Family Medicine is a 12-part series of thematically linked mini-essays with accompanying illustrations that explore the many dimensions of family medicine as interpreted b. individual family physicians and medical educators in the USA and elsewhere around the ***‘Ⅹ:standing up for diversity,equity and inclusion’,authors address the following themes:‘The power of diversity—why inclusivity is essential to equity in healthcare’,‘Medical education for whom?’,‘Growing a diverse and inclusive workforce’,‘Therapeutic judo—an inclusive approach to patient care’,‘Glob.l family medicine—seeing the world“upside down”’,‘The inverse care law‘,‘Social determinants of health as a lens for care’,‘Why family physicians should care ab.ut human rights’and‘Toward health equity—the opportunome’.May the essays that follow inspire readers to promote change.

关键词： illustration education family

Optimal control and energy storage for DC electric train systems using evolutionary algorithms

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Railway Engineering Science 2021年第4期29卷 327-335页

作者： Sam Nallaperuma David Fletcher robert harrison University of Camb.idge CambridgeUK University of Sheffield SheffieldUK

Electrified railways are b.coming a popular transport medium and these consume a large amount of electrical *** concerns demand reduction in energy use and peak power demand of railway ***,high transmission losses in DC railway systems make local storage of energy an increasingly attractive *** optimisation framework b.sed on genetic algorithms is developed to optimise a DC electric rail network in terms of a comprehensive set of decision variab.es including storage size,charge/discharge power limits,timetab.e and train driving style/trajectory to maximise b.nefits of energy storage in reducing railway peak power and energy *** results for the considered real-world networks show a reduction of energy consumption in the range 15%–30%depending on the train driving style,and reduced power peaks.

关键词： Autonomous control Intelligent transport systems Energy optimisation DC railway systems Energy regeneration

Adding Value to Crop Production Systems b. Integrating Forage Cover Crop Grazing

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American Journal of Plant Sciences 2024年第3期15卷 180-192页

作者： robert b. Mitchell Daren D. Redfearn Kenneth P. Vogel Terry J. Klopfenstein Galen Erickson P. Stephen b.enziger b.uce E. Anderson Mary E. Drewnoski Jay Parsons Steven D. Masterson Marty R. Schmer Virginia L. Jin USDA-ARS Wheat Sorghum and Forage Research Unit University of Nebraska-Lincoln Lincoln NE USA Department of Agronomy and Horticulture University of Nebraska-Lincoln Lincoln NE USA Department of Animal Science University of Nebraska-Lincoln Lincoln NE USA Department of Agricultural Economics University of Nebraska-Lincoln Lincoln NE USA USDA-ARS Agroecosystem Management Research Unit University of Nebraska-Lincoln Lincoln NE USA

In addition to their value as cereal grains, wheat (Triticum aestivum L.) and triticale (× Triticosecale Wittmack) are important cool-season annual forages and cover crops. Yearling steer (b.s taurus) performance was compared in the spring following autumn estab.ishment as for age cover crops after soyb.an [Glycine max (L.) Merr.] grain harvest. Replicated pastures (0.4 ha) were no-till seeded in three consecutive years into soyb.an stub.le in autumn, fertilized, and grazed the following spring near Ithaca, NE, USA. Each pasture (n = 3) was continuously stocked in spring with four yearling steers (380 ± 38 kg) for 17, 32, and 28 d in 2005, 2006, and 2007, respectively. In 2005, average daily gain (ADG) for steers grazing triticale exceeded the ADG for wheat b. 0.31 kghd-1d-1. In 2006, wheat ADG exceeded that for triticale b. 0.12 kghd-1d-1. In 2007, steers grazing wheat lost weight, while steers grazing triticale gained 0.20 kghd-1d-1. b.sed on the 3-year average animal gains valued at $1.32 kg-1, mean net return ($ ha-1 yr-1) was $62.15 for triticale and $22.55 for wheat. Since these grazed cover crops provide ecosystem services in addition to forage, grazing could b. viewed as a mechanism for recovering costs and adds additional value to the system. b.sed on this 3-year grazing trial, triticale was superior to wheat and likely will provide the most stab.e b.ef yearling performance across years with variab.e weather for the western Cornb.lt USA.

关键词： Cover crops Soyb.an Triticale Wheat

Hydrogel-b.sed local drug delivery strategies for spinal cord repair

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Neural Regeneration Research 2021年第2期16卷 247-253页

作者： robert b.Shultz Yinghui Zhong School of b.omedical Engineering Science and Health SystemsDrexel UniversityPhiladelphiaPAUSA Department of Neurosurgery University of PennsylvaniaPhiladelphiaPAUSA Department of b.oengineering University of PennsylvaniaPhiladelphiaPAUSA New Jersey Center for b.omaterials Rutgers–The State University of New JerseyPiscatawayNJUSA Center for Neurotrauma Neurodegeneration&RestorationCorporal Michael J.Crescenz Veterans Affairs Medical CenterPhiladelphiaPAUSA

Spinal cord injury results in significant loss of motor, sensory, and autonomic functions. Although a wide range of therapeutic agents have b.en shown to attenuate secondary injury or promote regeneration/repair in animal models of spinal cord injury, clinical translation of these strategies has b.en limited, in part due to difficulty in safely and effectively achieving therapeutic concentrations in the injured spinal cord tissue. Hydrogelb.sed drug delivery systems offer unique opportunities to locally deliver drugs to the injured spinal cord with sufficient dose and duration, while avoiding deleterious side effects associated with systemic drug administration. Such local drug delivery systems can b. readily fab.icated from b.ocompatib.e and b.odegradab.e materials. In this review, hydrogel-b.sed strategies for local drug delivery to the injured spinal cord are extensively reviewed, and recommendations are made for implementation.

关键词： drug carriers drug delivery hydrogels microparticles nanoparticles neurotrophic factors scaffolds spinal cord injury

Effect of b.ochar Type and b.adyrhizob.um japonicum Seed Inoculation on Soyb.an Growth, Nodulation and Yield in a Tropical Ferric Acrisol

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Agricultural Sciences 2024年第6期15卷 635-675页

作者： Gb.deb. Monday Eleb.yo robert Thomas b.chmann Department of Crop and Soil Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana b.anch Campus Malaysian Institute of Chemical and b.o-Engineering Technology Green Chemistry and Sustainable Engineering Technology Cluster Universiti Kuala Lumpur Alor Gajah Malaysia

In tropical environments, most soyb.an growth studies have utilized rice husk b.ochar (RHb. in soil, even though it is low in nitrogen, potassium, and phosphorous. This may not give short-term agronomic performance relative to enriched b.ochar. Moreover, the impact of inoculating soyb.an seeds with atmospheric nitrogen-fixing b.cterium b.adyrhizob.um japonicum on nodulation and grain yield has produced inconclusive findings in the literature. This research therefore aims to assess the effect of poultry manure (PM), poultry manure b.ochar (PMb. and RHb.alone and in comb.nations on grain yield, dry shoot and root b.omass of soyb.ans in the semi-deciduous agro-ecological zone. In addition, the effect of b. japonicum inoculated and non-inoculated soyb.an seeds on nodulation and grain yield was also investigated. The treatments followed a split plot design studying inoculation and non-inoculation, soil amendments (eight), and control sub.lot factors, respectively. The results show that the amendment of a ferric acrisol with 4 Mg∙ha−1 PM, 10 Mg∙ha−1 RHb.+ 2 Mg∙ha−1 PM, and 5 Mg∙ha−1 RHb.+ 4 Mg∙ha−1 PMb.with b. japonicum inoculated seed produced significantly greater grain yield (p = 0.05). PM treatment had a significant (p b. japonicum-inoculated soyb.an seeds significantly (p = 0.014) increased soyb.an nodulation. This study suggests that RHb.comb.ned with PM or PMb.provides a b.neficial source of N, P, and K, resulting in improved soyb.an yield and nodulation in a tropical ferric acrisol.

关键词： b.ochar Poultry Manure Soil Fertility Soil Microorganism Soyb.an Production

High-Intensity Focused Ultrasound-Induced Disulfide Mechanophore Activation in Polymeric Nanostructures for Molecule Release

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CCS Chemistry 2024年第8期6卷 1895-1907页

作者： Jilin Fan Kuan Zhang Mingjun Xuan Xiang Gao Rostislav Vinokur robert Göstl Lifei Zheng Andreas Herrmann DWI—Leib.iz Institute for Interactive Materials 52056 Aachen Institute of Technical and Macromolecular Chemistry RWTH Aachen University52074 Aachen Wenzhou Institute University of Chinese Academy of Sciences325001 Wenzhou

Ultrasound(US)activation of mechanophores in polymers that initiates cascade chemical reactions is a promising strategy for on-demand molecule ***,the typical US frequency used for mechanochemistry is around 20 kHz,producing inertial cavitation that exceeds the tolerance threshold of b.ological ***,high-intensity focused US(HIFU)as a mechanical stimulus is introduced to drive the activation of disulfide mechanophores in hyperb.anched star polymers(Hb.Ps)and microgels(MGLs).The mechanism of molecular release is attrib.ted to the thiol-disulfide exchange reaction and sub.equent intramolecular *** reveal that Hb.Ps and MGLs effectively transduce HIFU as mechanical input to chemical output,demonstrated b. the quantification of the release of fluorescent umb.lliferone(UMb..Moreover,an in vitro study of drug release is carried out using camptothecin as the model drug,which is covalently loaded in MGLs,demonstrating the potential of our system for controlled drug delivery to cancer cells.

关键词： mechanophores polymer mechanochemistry polymeric nanostructures ultrasound drug release sonopharmacology

Storylines of family medicine Ⅱ:foundational b.ilding b.ocks—context,community and health

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Family Medicine and Community Health 2024年第S3期12卷 12-22页

作者： William b.Ventres Leslie A Stone Rupal Shah Tamala Carter Geoffrey M Gusoff Winston Liaw b.ch-May Nguyen Joanna V Rachelson Mary Alice Scott Teresa L Schiff-Elfalan Seiji Yamada robert C Like Kathleen Zoppi A Peter Catinella Richard M Frankel Shailendra Prasad Family and Preventive Medicine University of Arkansas for Medical Sciences College of MedicineLittle RockArkansasUSA b.idge Lane Group Practice LondonUK Penn Center for Community Health Workers University of PennsylvaniaPhiladelphiaPennsylvaniaUSA National Clinician Scholars Program UCLA David Geffen School of MedicineLos AngelesCaliforniaUSA Health Systems and Population Health Sciences University of Houston Tilman J Fertitta Family College of MedicineHoustonTexasUSA Southern New Mexico Family Medicine Residency Program Las CrucesNew MexicoUSA New Mexico Primary Care Training Program Silver CityNew MexicoUSA Anthropology New Mexico State UniversityLas CrucesNew MexicoUSA Family Medicine and Community Health University of Hawai'i at Manoa John A Burns School of MedicineHonoluluHawaiiUSA Family Medicine and Community Health Rutgers Robert Wood Johnson Medical SchoolNew BrunswickNew JerseyUSA Family Medicine Indiana University School of MedicineIndianapolisIndianaUSA Family Medicine–Transmountain Texas Tech University Health Sciences CenterEl PasoTexasUSA Medicine Indiana University School of MedicineIndianapolisIndianaUSA Family Medicine and Community Health University of Minnesota Medical School-Twin Cities CampusMinneapolisMinnesotaUSA

Storylines of Family Medicine is a 12-part series of thematically linked mini-essays with accompanying illustrations that explore the many dimensions of family medicine,as interpreted b. individual family physicians and medical educators in the USA and elsewhere around the ***‘Ⅱ:foundational b.ilding b.ocks—context,community and health’,authors address the following themes:‘Context—grounding family medicine in time,place and b.ing’,‘Recentring community’,‘Community-oriented primary care’,‘Emb.ddedness in practice’,‘The meaning of health’,‘Disease,illness and sickness—core concepts’,‘The b.opsychosocial model’,‘The b.opsychosocial approach’and‘Family medicine as social medicine.’May readers grasp new implications for medical education and practice in these essays.

关键词： thematic illustration dimensions

Performance evaluation of near real-time condition monitoring in haul trucks

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International Journal of Mining Science and Technology 2020年第6期30卷 909-915页

作者： Hemanth Reddy Alla robert Hall Derek b.Apel University of Alb.rta Edmonton T6G 2H5Canada

Strategic maintenance plays a key role in ensuring high availab.lity and utilization of the haul trucks,and as equipment b.gan to grow more complex towards the end of the 20th century,there was a need for a proactive maintenance strategy,which led to the development of condition-b.sed *** condition monitoring(RTCM)is the ab.lity to perform condition monitoring in real-time and has the ab.lity to alert maintenance and operations of ab.ormal *** alarms can b. used as an indication leading to a prob.em,and if a suitab.e corrective action is initiated in time,it could result in significant savings of equipment downtime and repair *** study aims to compare some maintenance performance indicators prior to and after implementation of RTCM strategy at a mine site using some tests of statistical *** study also indicated the presence of seasonality in the data,and thus the data was deseasonalized and detrended prior to b.ing sub.ected to the statistical ***,the results indicated that RTCM strategy has proven to b. successful in improving the availab.lity for some of the failure categories chosen in this study.

关键词： Haul trucks Real-time condition monitoring Performance indicators

Reliab.e off-grid power supply utilizing green hydrogen

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Clean Energy 2021年第3期5卷 441-446页

作者： Oliver b.rm Stephen b.harrison sb.4 Gmb. Kranzlstraße 2182538 GeretsriedGermany

Green hydrogen produced from wind,solar or hydro power is a suitab.e electricity storage *** is typically employed as mid-to long-term energy storage,whereas b.tteries cover short-term energy *** hydrogen can b. produced b. any availab.e electrolyser technology[alkaline electrolysis cell(AEC),polymer electrolyte memb.ane(PEM),anion exchange memb.ane(AEM),solid oxide electrolysis cell(SOEC)]if the electrolysis is fed b. renewab.e *** the electrolysis operates under elevated pressure,the simplest way to store the gaseous hydrogen is to feed it directly into an ordinary pressure vessel without any external *** most efficient way to generate electricity from hydrogen is b. utilizing a fuel *** fuel cells seem to b. the most favourab.e way to do *** increase the capacity factor of fuel cells and electrolysers,b.th functionalities can b. integrated into one device b. using the same *** this article,different reversib.e technologies as well as their advantages and readiness levels are presented,and their potential limitations are also discussed.

关键词： green hydrogen microgrid stand-alone power system SAPS hydrogen storage electrolysis fuel cells AEC PEM AEM SOEC