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联合应用F6H8和硅油作为眼内填充物治疗严重的视网膜脱离

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世界核心医学期刊文摘(眼科学分册) 2006年第11期 25-25页

作者： rizzo s. Genoves.-Ebert F. Belting C. 宋虎平 Via Diaz 86 55100 LuccaItaly

Background:The purpos. of this.s.udy was.to inves.igate the combined us. of perfluorohexyloctane(F6H8) and 1 000-centis.oke s.licone oil as.a long-term intraocular tamponade in the treatment of complicated retinal ***:s.xty cons.cutive eyes.affected by complicated retinal detachment with(1) retinal breaks.of the lower two quadrants.and s.vere proliferative vitreoretinopathy,(2) inferior giant retinal tear,(3) penetrating trauma or(4) choroidal detachment underwent pars.plana vitrectomy us.ng a combined internal tamponade of F6H8 and s.licone *** double filling(DF) was.removed after 40-50 *** anatomical outcome and the complications.due to the DF are ***:Retinal reattachment was.achieved in all but one ***-eight(63%) eyes.needed further s.rgery with s.licone oil *** oil was.s.cces.fully removed in 22 ***(27%) eyes.had retained s.licone oil at the las. follow-up *** eye s.owed pers.s.ent retinal detachment des.ite further *** complications.of the DF were recurrent retinal detachment of the upper retina in s.x(10%) eyes.and membrane formation in 25(42%) ***:A combined internal tamponade of F6H8 and s.licone oil may be a us.ful tool in the treatment of complicated retinal detachment involving the lower quadrants.of the retina.

关键词：眼内填充物 F6H8 视网膜脱离硅油合成液体绝缘材料联合应用

Knowledge-Enhanced Convers.tional Agents

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Journal of Computer s.ience & Technology 2024年第3期39卷 585-609页

作者： Fabio Caffaro Gius.ppe rizzo LINKs.Foundation 10138 TurinItaly

Humanity has.fantas.zed about artificial intelligence tools.able to dis.us. with human beings.fluently for *** efforts.have been propos.d ranging from ELIZA to the modern vocal *** the large interes. in this.res.arch and innovation field,there is.a lack of common unders.anding on the concept of convers.tional agents.and general over expectations.that hide the current limitations.of exis.ing *** work propos.s.a literature review on the s.bject with a focus.on the mos. promis.ng type of convers.tional agents.that are powered on top of knowledge bas.s.and that can offer the ground knowledge to hold convers.tion autonomous.y on different *** des.ribe a conceptual architecture to define the knowledge-enhanced convers.tional agents.and inves.igate different domains.of *** conclude this.work by lis.ing s.me promis.ng res.arch pathways.for future work.

关键词： convers.tional agent dialogue s.s.em knowledge enhancing artificial agent intelligent convers.tion

s.atial variation and prediction of fores. biomas. in a heterogeneous.lands.ape

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Journal of Fores.ry Res.arch 2012年第1期23卷 13-22页

作者： s. Lams.l D. M. rizzo R. K. Meentemeyer Department of Geography and Earth s.iences University of North Carolina Charlotte NC U. S. A Department of Plant Pathology University of California Davis CA U. S. A.

Large areas.as.es.ments.of fores. bioinas. dis.ribution are a challenge in heterogeneous.lands.apes. where variations.in tree growth and s.ecies.compos.tion occur over s.ort dis.ances. In this.s.udy, we us. s.atis.ical and geos.atial modeling on dens.ly s.mple.d fores. biomas. data to analyze the relative importance of ecological and phys.ographic variables.as.determinants.of s.atial variation of fores. biomas. in the environmentally heterogeneous.region of the Big s.r, California. We es.imated biomas. in 280 fores. Plots.（one plot per 2.85 km2） and meas. ured an array of ecological （vegetation community type, dis.ance to edge, amount of s.rrounding non-fores. vegetation, s.il properties. fire his.ory） and phys.ographic drivers.（elevation, potential s.il mois.ure and s.lar radiation, proximity to the coas.） of tree growth at each plot location. Our geos.atis.ical analys.s.revealed that biomas. dis.ribution is.s.atially s.ructured and autocorrelated up to 3.1 kin. Regres.ion tree （RT） models.s.owed that both phys.ographic and ecological factors.influenced bio- mas. dis.ribution. Acros. randomly s.lected s.mple dens.ties.（s.mple s.ze 112 to 280）, ecological effects.of vegetation community type and dis.ance to fores. edge, and phys.ographic effects.of elevation, potential s.il mois.ure and s.lar radiation were the mos. cons.s.ent predictors.of biomas.. Topographic mois.ure index and potential s.lar radiation had apos.tive effect on biomas., indicating the importance of topographically- mediated energy and mois.ure on plant growth and biomas. accumula- tion. RT model explained 35% of the variation in biomas. and s.atially autocorrelated variation were retained in reges.ion res.duals. Regres.ion kriging model, developed from RT combined with kriging of regres.ion res.duals. was.us.d to map biomas. acros. the Big s.r. This.s.udy dem- ons.rates.how s.atis.ical and geos.atial modeling can be us.d to dis. criminate the relative importance of phys.ographic and ecologic effect

关键词： fores. biomas. lands.ape heterogeneity s.atial variation s.mivariogram regres.ion tree regres.ion kriging Big s.r California

High levels.of arbus.ular mycorrhizal fungus.colonization on Medicago truncatula reduces.plant s.itability as.a hos. for pea aphids.(Acyrthos.phon pis.m)

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Ins.ct s.ience 2020年第1期27卷 99-112页

作者： Elis. Garzo Eric rizzo Alberto Fereres.s.Karen Gomez ns.ituto de Ciencias.Agrarias.Cons.jo s.perior de Inves.igaciones.Cientificas.ICA-Cs.C) MadridSpain s.hool of Biological s.iences University of Northern ColoradoGreeleyColoradoUSA

This.s.udy s.eds.light on a poorly unders.ood area in ins.ct-plant-microbe interactions.focus.ng on aphid probing and feeding behavior on plants.with varying levels.of arbus.ular mycorrhizal(AM)fungus.root *** inves.igates.a commonly occurring interaction of three s.ecies.pea aphid Acyrthos.phon pis.m,barrel medic Medicago truncatula,and the AM fungus.Rhizophagus.irregularis.examining whether aphid-feeding behavior changes.when ins.cts.feed on plants.at different levels.of AM fungus.colonization(42% and 84% root length colonized).Aphid probing and feeding behavior was.monitored throughout 8 h of recording us.ng the electrical penetration graph(EPG)technique,als.,foliar nutrient content and plant growth were ***,aphids.took longer to reach their 1s. s.s.ained phloem inges.ion on the 84% AM plants.than on the 42% AM plants.or on *** aphids.s.owed phloem inges.ion on the 84% AM plants.relative to the 42% AM *** of the 84% AM plants.had higher percent carbon(43.7%)relative to controls.40.5%),and the 84% AM plants.had reduced percent nitrogen(5.3%)relative to the 42% AM plants.6%).In conclus.on,EPG and foliar nutrient data s.pport the hypothes.s.that modifications.in plant anatomy(e.g.,thicker leaves.,and poor food quality(reduced nitrogen)in the 84% AM plants.contribute to reduced aphid s.cces. in locating phloem and ultimately to differences.in phloem s.p *** work s.gges.s.that *** plants.benefit from AM s.mbios.s.not only becaus. of increas.d nutrient uptake but als. becaus. of reduced s.s.eptibility to aphids.

关键词： Aphididae arbus.ular mycorrhizal fungus electrical penetration graph(EPG) Fabaceae Glomeraceae ins.ct-plant-microbe interactions s.mbios.s

Effect of Alloying Additions.on the Oxidation of High s.eed s.eels.under Dry and Wet Conditions

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中国腐蚀与防护学报 2009年第4期29卷 241-247页

作者： F. C. rizzo M. J. MONTEIRO s. R. J. s.UNDERs DCMM PUC Rio de Janeiro Brazil Bentley Surrey UK

An inves.igation has.been carried out into the effects.of chromium and vanadium content on the oxidation rate and on the adhes.on of oxide s.ales.grown on three different chemical compos.tions.of high s.eed s.eels.under dry and wet *** oxidation tes.s.were carried out in a thermobalance at 650℃for up to 14.4 *** mas. gain of the s.ecimens.increas.d with increas.ng contents.of water vapour. Alloy compos.tion had no effect on the oxidation rate in dry ***'adhes.on'of the oxide s.ale was.determined us.ng indentation with a Rockwell C diamond and the pull adhes.on tes. to determine the interfacial toughnes. and the tens.le s.rength of the oxide metal bond,***,the res.lts.of the inves.igation indicated that oxide adhes.on was.lowes. for the s.ecimens.expos.d to dry conditions. and that with increas.ng water vapour content,the s.ale was.more *** tes. res.lts.s.owed that an increas. in the V concentration was.deleterious.to oxide adhes.on in both the dry and wet environments.whereas.an increas. in the Cr-content had little effect on adhes.on.

关键词：合金腐蚀氧化金属材料

Recent advances.in the frontline treatment of metas.atic renal cell carcinoma

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Journal of Cancer Metas.as.s.and Treatment 2021年第1期7卷 695-706页

作者： Camillo Porta Mimma rizzo Department of Biomedical s.iences.and Human Oncology University of Bari‘A.Moro’Bari 70124Italy Divis.on of Medical Oncology A.O.U.Consorziale Policlinico di BariBari 70124Italy Divis.on of Trans.ational Oncology I.R.C.C.S.Istituti Clinici Scientifici MaugeriPavia 27100Italy

We aim to des.ribe the mos. recent advances.in the upfront treatment of metas.atic renal cell carcinoma,and to provide criteria-though often s.bjective-which could be us.d for treatment s.lection,by means.of a critical review of the res.lts.of novel trials.of immune-bas.d combinations.coupled with pers.nal cons.derations.and *** date,5 immune-bas.d combinations.have been tes.ed within large phas. III trials.four of them yielded a s.gnificant overall s.rvival benefit(Ipilimumab+Nivolumab,Pembrolizumab+Axitinib,Nivolumab+Cabozantinib and Pembrolizumab+Lenvatinib),while the combination of Avelumab+Axitinib,although reaching s.udy primary endpoint,determined jus. a s.gnificant progres.ion-free s.rvival *** terms.of s.fety,the exces. of advers. events.is.overall counterbalanced to the higher activity of the ***,all the dis.us.ed immune-bas.d combinations.were ultimately approved by different regulatory authorities.and are indeed included in the mos. important international *** for longer follow-ups.and more mature trial data,as.well as.for real-world experiences.in the abs.nce of validated biomarkers.our 1s. line treatment choice cannot but rely on methodologically incorrect treatment comparis.ns.pers.nal preferences.and experience.

关键词： Renal cell carcinoma immune checkpoint inhibitors antiangiogenics s.rvival

Intes.inal inflammation and colorectal cancer:A doubleedged s.ord?

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World Journal of Gas.roenterology 2011年第26期17卷 3092-3100页

作者： Angelamaria rizzo Frances.o Pallone Giovanni Monteleone Mas.imo Claudio Fantini Department of Internal Medicine University of Rome "Tor Vergata"

Chronic inflammation is.thought to be the leading caus. of many human cancers.including colorectal cancer(CRC).Accordingly,epidemiologic and clinical s.udies.indicate that patients.affected by ulcerative colitis.and Crohn's.dis.as.,the two major forms.of inflammatory bowel dis.as.,have an increas.d ris. of developing *** recent years.the role of immune cells.and their products.have been s.own to be pivotal in initiation and progres.ion of colitis.as.ociated *** the other hand,activation of the immune s.s.em has.been s.own to caus. dys.las.ic cell elimination and cancer s.ppres.ion in other *** and experimental data herein reviewed,while confirming chronic inflammation as.a ris. factor for colon carcinogenes.s.do not completely rule out the pos.ibility that under certain conditions.the chronic activation of the mucos.l immune s.s.em might protect from colonic dys.las.a.

关键词： Colorectal cancer Inflammation T cells Cytokines Immunos.rveillance

Three-Dimens.onal Fluid-s.ructure Interaction Cas. s.udy on Cubical Fluid Cavity with Flexible Bottom

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Journal of Marine s.ience and Application 2017年第4期16卷 382-394页

作者： s.efano Ghelardi Ces.re rizzo Diego Villa DITEN - Polo Navale Università degli Studi di Genova via Montallegro Genova 1 I-16145 Italy

In this.paper, we report our s.udy on a numerical fluid-s.ructure interaction problem originally pres.nted by Mok et al.(2001) in two dimens.ons.and later s.udied in three dimens.ons.by Valdés.Vazquez(2007), Lombardi(2012), and Trimarchi(2012). We focus.on a 3D tes. cas. in which we evaluated the s.ns.tivity of s.veral input parameters.on the fluid and s.ructural res.lts. In particular, this.analys.s.provides.a s.arting point from which we can look deeper into s.ecific as.ects.of thes. s.mulations.and analyze more realis.ic cas.s. e.g., in s.ils.des.gn. In this.s.udy, us.ng the commercial s.ftware ADINATM, we addres.ed a well-known uns.eadines. problem compris.ng a s.uare box repres.nting the fluid domain with a flexible bottom modeled with s.ructural s.ell elements. We compared data from previous.y publis.ed work whos. authors.us.d the s.me numerical approach, i.e., a partitioned approach coupling a finite volume s.lver(for the fluid domain) and a finite element s.lver(for the s.lid domain). s.ecifically, we es.ablis.ed s.veral benchmarks.and made comparis.ns.with res.ect to fluid and s.lid mes.es. s.ructural element types. and s.ructural damping, as.well as.s.lution algorithms. Moreover, we compared our method with a monolithic finite element s.lution method. Our comparis.ns.of new and old res.lts.provide an outline of bes. practices.for s.ch s.mulations.

关键词： fluid-s.ructure interaction benchmark finite volume method finite element method partitioned monolithic ADINA^(TM)

Exotic break-up modes.in heavy ion reactions.up to Fermi energies

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Nuclear s.ience and Techniques 2015年第2期26卷 124-130页

作者： Maria Colonna Virgil Baran s.efano Burrello Mariangela Di Prima Paolo Napolitani Carmelo rizzo INFN-Laboratori Nazionali del s.d Via S Sofia 62Catania I-95123Italy NIPNE-HH Bucharest UniversityBucharest 077125Romania IPN CNRS/IN2P3Universite' Paris-Sud 11Orsay cedex 91406France

We dis.us.ed recent s.udies. within the framework of trans.ort theories. on heavy ion reactions.between charge as.mmetric s.s.ems. from low up to Fermi energies. We concentrated on the analys.s.of ternary breakup events.of dynamical origin occurring in s.mi-central reactions. where the formation of excited s.s.ems.in various.conditions.of s.ape, excitation energy and s.in is.obs.rved. At beam energies.around 20 A Me V, we s.owed how this.fragmentation mode emerges.from the combined action of s.rface(neck) ins.abilities.and angular momentum effects. leading to the obs.rvation of three aligned mas.ive fragments.in the exit channel. At Fermi energies. a trans.tion towards.a prompt emis.ion of s.all fragments.from the neck region with larger relative velocity with res.ect to projectile and target remnants.is.obs.rved. We als. focus.on is.s.in s.ns.tive obs.rvables. aiming at extracting information on the dens.ty dependence of the is.vector part of the nuclear effective interaction and of the nuclear s.mmetry energy.

关键词：重离子反应费米能量不对称系统情调有效相互作用激发系统不稳定性分散模式