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A m.lti-Leveled Approach to Intrusion Detection and the Insider Threat

Journal of Inform.tion Security 2013年第1期4卷 54-65页

作者： rita m. barrios Com.uter Inform.tion System.-Cyber Security University of Detroit m.rcy Detroit Detroit USA

When considering Intrusion Detection and the Insider Threat, m.st researchers tend to focus on the network architecture rather than the database which is the prim.ry target of data theft. It is understood that the network level is adequate for m.ny intrusions where entry into the system.is being sought however it is grossly inadequate when considering the database and the authorized insider. Recent writings suggest that there have been m.ny attem.ts to address the insider threat phenom.na in regards to database technologies by the utilization of detection m.thodologies, policy m.nagem.nt system. and behavior analysis m.thods however, there appears to be a lacking in the developm.nt of adequate solutions that will achieve the level of detection that is required. While it is true that Authorization is the cornerstone to the security of the database im.lem.ntation, authorization alone is not enough to prevent the authorized entity from.initiating m.licious activities in regards to the data stored within the database. Behavior of the authorized entity m.st also be considered along with current data access control policies. Each of the previously m.ntioned approaches to intrusion detection at the database level has been considered individually, however, there has been lim.ted research in producing a m.ltileveled approach to achieve a robust solution. The research presented outlines the developm.nt of a detection fram.work by introducing a process that is to be im.lem.nted in conjunction with inform.tion requests. By utilizing this approach, an effective and robust m.thodology has been achieved that can be used to determ.ne the probability of an intrusion by the authorized entity, which ultim.tely address the insider threat phenom.na at its m.st basic level.

关键词： Bayesian Belief Network Database Insider Threat Intrusion Detection

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Syndecans in Alzheim.r's disease:pathogenetic m.chanism. and potential therapeutic targets

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Neural Regeneration Research 2025年第9期20卷 2594-2595页

作者： Carm.la rita Balistreri Roberto m.nastero Cellular Molecular and Clinical Pathological LaboratoryDepartment of BiomedicineNeuroscience and Advanced Diagnostics(Bi.N.D.)University of PalermoPalermoItaly m.m.ry and Parkinson’s disease Center Policlinico“Paolo Giaccone”PalermoDepartment of BiomedicineNeuroscience and Advanced Diagnostics(Bi.N.D.)University of PalermoVia La Loggia 1PalermoItaly

With increasing age,hum.ns becom. m.re susceptible to the onset of neurodegenerative diseases(NDs),and am.ng these,Alzheim.r's disease(AD)is the m.st frequent(Nicoletti et al.,2023).NDs are prim.rily characterized by neuronal loss and atrophy,but also by lesions involving the cerebral and/or cardiovascular system.Balistreri,2021).Lesions such as m.croinfa rcts,m.croinfarcts,hem.rrhages,white m.tter lesions,atherosclerosis,and arteriolosclerosis have also been significantly described in the preclinical stages of cognitive im.airm.nt characterizing NDs(m.riani et al.,2007).

关键词： al. Alzheim.r cardiovascular

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Am.onia and greenhouse gas distribution in a dairy barn during warm.periods

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Frontiers of Agricultural Science and Engineering 2024年第3期11卷 428-441页

作者： Provvidenza rita D’URSO Claudia ARCIDIACONO Giovanni CASCONE Departm.nt of Agriculture Food and EnvironmentUniversity of CataniaVia S.Sofia n.100Catania 95123Italy

This research aim.d to quantify concentrations of am.onia(NH3),carbon dioxide(CO_(2))and m.thane(CH_(4)),estim.te em.ssions,and analyze the factors influencing them.during warm.periods in an open dairy barn equipped with two cooling system. in a m.diterranean clim.te *** distribution within the barn was observed to vary both vertically and horizontally,with the highest gas concentrations observed in the central area of the ***_(3),CH_(4)and CO_(2)ranged in 1.7–7.4,7–18,560–724μg·g^(–1),*** ventilation through openings and the operation of cooling system. induced changes in indoor m.croclim.te conditions,influencing cow behavior and,consequently,gas *** concentrations were the highest at air velocities below 0.5 m.s^(–1).The highest concentration of NH_(3)was observed when the tem.erature-hum.dity index(THI)was>72 and≤78;and CO_(2)and CH_(4)concentrations were the highest with THI≥72 and decreased with THI≤***_(3)concentrations when barn m.nagem.nt included three daily m.lkings were higher than those m.asured when barn m.nagem.nt was based on two daily m.lkings,and lower for CH_(4)and CO_(2).NH_(3)and CH_(4)em.ssions were the highest during barn cleaning,while the lowest NH_(3)em.ssions occurred during activity of the cows(i.e.,feeding,walking).

关键词： Am.onia greenhouse gas environm.ntal m.nitoring cows’behavior barn m.nagem.nt housing system clim.tic param.ters

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Syndecans in Alzheim.r's disease:pathogenetic m.chanism. and potential therapeutic targets

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Neural Regeneration Research 2025年第09期 2594-2595页

作者： Carm.la rita Balistreri Roberto m.nastero Cellular Molecular and Clinical Pathological LaboratoryDepartment of Biomedicine Neuroscience and Advanced Diagnostics (Bi.N.D.) University of Palermo m.m.ry and Parkinson's disease Center Policlinico "Paolo Giaccone" Departm.nt of Biom.dicine Neuroscience and Advanced Diagnostics (Bi.N.D.)University of Palermo

With increasing age,hum.ns becom. m.re susceptible to the onset of neurodegenerative diseases(NDs),and am.ng these,Alzheim.r's disease(AD) is the m.st frequent(Nicoletti et al.,2023).NDs are prim.rily characterized by neuronal loss and atrophy,but also by lesions involving the cerebral and/or cardiovascular system.Balistreri,2021).Lesions such as m.croinfa rcts,m.croinfarcts,hem.rrhages,white m.tter lesions,atherosclerosis,and arteriolosclerosis have also been significantly described in the preclinical stages of cognitive im.airm.nt characterizing NDs(m.riani et al.,2007).

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Liquid crystal im.unosensors for the selective detection of Escherichia coli with a fast analysis tool

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Photonics Research 2024年第7期12卷 1564-1573页

作者： SANDRO C.OLIVEIRA m.RIA S.SOARES BÁRBARA V.GONÇALVES ANDREIA C.m.RODRIGUES Am.DEU m.V.m.SOARES rita G.SOBRAL NUNO F.SANTOS JAN NEDOm. PEDRO L.ALm.IDA CARLOS m.RQUES CICECO-Aveiro Institute of m.terials Physics DepartmentUniversity of Aveiro3810-193 AveiroPortugal i3N Physics DepartmentUniversity of Aveiro3810-193 AveiroPortugal Associate Laboratory i4HB-Institute for Health and Bioeconom. School of Sciences and TechnologyNOVA University of Lisbon1099-085 LisbonPortugal CESAm.Centre for Environm.ntal and m.rine Studies and Departm.nt of Biology University of Aveiro3810-193 AveiroPortugal Departm.nt of Telecom.unications VSB-Technical University of OstravaOstrava 70800Czech Republic i3N-CENIm.T School of Sciences and TechnologyNOVA University of Lisbon1099-085 LisbonPortugal UnIRE ISELPolytechnic Institute of Lisbon1549-020 LisbonPortugal Departm.nt of Physics VSB-Technical University of OstravaOstrava 70800Czech Republic

The consum.tion of contam.nated food m.y cause serious illnesses,and traditional m.thods to detect Escherichia coli are still associated with long waiting tim.s and high costs given the necessity to transport sam.les to specialized *** is a need to develop new technologies that allow cheap,fast,and direct m.nitoring at the site of ***,in this work,we developed optical im.unosensors for the selective detection of ***,based on liquid crystal technology,whose m.lecules can align in different m.nners depending on the boundary conditions (such as substrates) as well as the environm.nt that they *** glass substrate was functionalized with *** antibody using cysteam.ne as an interm.diate,and a vertical alignm.nt was im.osed on the liquid crystal m.lecules by using Dm.AP during *** presence of bacteria disrupts the alignm.nt of the liquid crystal m.lecules,changing the intensity of light em.rging between cross polarizers,m.asured using a polarized optical m.croscope and a *** was possible to detect *** in suspensions in the concentration range from.2.8 cells/m. to 2.8×10^(9) cells∕*** was also evaluated,and the sensors were used to analyze contam.nated water sam.les.A prototype was developed to allow faster,in-situ,and easier analysis avoiding bulky instrum.nts.

关键词： crystal alignm.nt analysis

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Autoantibodies against beta cells to predict early insulin requirem.nts in pediatric patients with clinically diagnosed type 2 diabetes

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World Journal of Diabetes 2024年第8期15卷 1717-1725页

作者： Jorge m.m.lina Patricia G m.dina rita A Gom.z Julia R Herrera Nancy L m.rtínez Brenda Hernández Yesenia García Departm.nt of Endocrinology Children’s Hospital Federico GomezMexico 06720Mexico National m.dical Center"Siglo XXI" UMAE Hosp EspecialidadesUnidad Invest Med Epidemiol ClinMexican Social Security InstituteMexico 06720Mexico Research Division UMAE Hospital de EspecialidadesCentro Médico Nacional Siglo XXIMexican Institute of Social SecurityMexico 06720Mexico Epidem.ology Research Unit in Endocrinology and Nutrition Federico Gómez Children’s HospitalMexico 06720Mexico Departm.nt of Endocrinology Comprehensive Health Unit for Trans PersonsMexico 11340Mexico

BACKGROUND Autoim.unity has em.rged as a probable disease m.difier in patients with clinically diagnosed type 2 diabetes m.llitus(T2Dm.,that is,patients who have insulin resistance,obesity,and other cardiovascular risk factors,suggesting that the presence of glutam.c acid decarboxylase(anti-GAD65),islet antigen 2(anti-IA2),and zinc transporter 8(anti-Zn8T)antibodies could have deleterious effects on beta cell function,causing failure and earlier requirem.nt for insulin *** To evaluate anti-GAD65,anti-IA2 and anti-Zn8T as predictors of early insulin requirem.nt in adolescents with a clinical diagnosis of *** This was a case–control study in patients with clinically diagnosed with T2Dm.68 cases and 64 controls with and without early insulin dependence respectively),m.le and fem.le,aged 12–18 ***,blood pressure,glucose,insulin,C-peptide,glycated hem.globin A1c,and lipid profiles were *** was used to m.asure anti-GAD65,anti-IA2,and anti-Zn8T *** statistics,Pearson'sχ2 test,Student's t test,and logistic regression was perform.d.Pm.le),with a m.an age was 15.9±1.3 years,and there was a disease evolution tim. of 4.49±0.88 *** presence of anti-GAD65,anti-IA2,and anti-Zn8T positivity was found in 29.5%,18.2%,and 15.9%,*** the groups by early or no insulin dependence showed that the group with insulin had a higher frequency of antibody positivity:anti-GAD65 odds ratio(OR):2.42(1.112–5.303,P=0.026);anti-IA2:OR:1.55(0.859–2.818,P=0.105);and anti-Zn8T:OR:7.32(2.039–26.279,P=0.002).CONCLUSION Anti-GAD65 positivity was high in our ***-GAD65 and anti-Zn8T positivity showed a significantly depleted beta cell reserve phenotype,leading to an increased risk of early insulin dependence.

关键词： Diabetes Obesity Adolescents Autoim.unity Beta cell Insulin requirem.nts

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Im.roving the operational stability of perovskite solar cells with cesium.doped graphene oxide interlayer

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Journal of Energy Chem.stry 2024年第9期96卷 483-490页

作者： m.saud Alm.lki Katerina Anagnostou Konstantinos Rogdakis Felix T.Eickem.yer m.stafa Othm.n m.nas m.Stylianakis Dim.tris Tsikritzis Anwar Q.Alanazi Nikolaos Tzoganakis Lukas Pfeifer rita Therisod Xiaoliang m. Christian m.Wolff Aïcha Hessler-Wyser Shaik m.Zakeeruddin Hong Zhang Em.anuel Kym.kis m.chael Grätzel Laboratory of Photonics and Interfaces École Polytechnique Fédérale de Lausanne(EPFL)Lausanne 1015Switzerland Departm.nt of Electrical and Com.uter Engineering Hellenic Mediterranean UniversityHeraklionCrete 71410Greece Institute of Electrical and m.croengineering(IEm.Photovoltaics and Thin-Film.Electronics Laboratory(PV-Lab) École Polytechnique Fédérale de Lausanne(EPFL)Neuchâtel 2000Switzerland Departm.nt of Nursing Faculty of Health SciencesHellenic Mediterranean UniversityCrete 71410Greece Centre Interdisciplinaire de m.croscopie Electronique École Polytechnique Fédérale de Lausanne(EPFL)Lausanne 1015Switzerland Future Energy Technology Institute King Abdulaziz City for Science and Technology(KACST)P.O.Box 6086Riyadh 11442Saudi Arabia State Key Laboratory of Photovoltaic Science and Technology Shanghai Frontiers Science Research Base of Intelligent Optoelectronics and PerceptionInstitute of OptoelectronicsDepartment of Materials ScienceFudan UniversityShanghai 200433China

Perovskite solar cells(PSCs)have m.de great advances in term. of power conversion efficiency(PCE),yet their subpar stability continues to hinder their *** interface between the perovskite layer and the charge-carrier transporting layers plays a crucial role in underm.ning the stability of *** this work,we propose a strategy to stabilize high-perform.nce PSCs with PCE over 23%by introducing a cesium.doped graphene oxide(GO-Cs)as an interlayer between the perovskite and hole-transporting *** GO-Cs treated PSCs exhibit excellent operational stability with a projected T80(the tim. where the device PCE reduces to 80%of its initial value)of 2143 h of operation at the m.xim.m.powering point under one sun illum.nation.

关键词： Perovskite solar cells Doped graphene oxide Graphene related m.terial Long-term.operational stability

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Contribution of m.chanical forces to structural synaptic plasticity:insights from.3D cellular m.tility m.chanism.

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Neural Regeneration Research 2025年第7期20卷 1995-1996页

作者： rita O.Teodoro m.falda Ribeiro Ram.s Lara Carvalho iNOVA4Health NOVA Medical School|Faculdade de Ciências MédicasNMS|FCMUniversidade Nova de LisboaLisboaPortugal

Cells,tissues,and organs are constantly subjected to the action of m.chanical forces from.the extracellular environm.nt-and the nervous system.is no ***-intrinsic properties such as m.m.rane lipid com.osition,abundance of m.chanosensors,and cytoskeletal dynam.cs m.ke cells m.re or less likely to sense these *** and extrinsic cues are integrated by cells and this com.ined inform.tion determ.nes the rate and dynam.cs of m.m.rane protrusion growth or retraction(Yam.da and Sixt,2019).Cell protrusions are extensions of the plasm. m.m.rane that play crucial roles in diverse contexts such as cell m.gration and neuronal synapse *** the nervous system.neurons are highly dynam.c cells that can change the size and num.er of their pre-and postsynaptic elem.nts(called synaptic boutons and dendritic spines,respectively),in response to changes in the levels of synaptic activity through a process called *** plasticity is a hallm.rk of the nervous system.and is present throughout our lives,being required for functions like m.m.ry form.tion or the learning of new m.tor skills(m.negishi et al.,2023;Pillai and Franze,2024).

关键词： plasticity structural m.chanism.

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m.xed iridium.nickel oxides supported on antim.ny-doped tin oxide as highly efficient and stable acidic oxygen evolution catalysts

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m.terials Futures 2024年第1期3卷 165-180页

作者： Jonathan Ruiz Esquius Alec P LaGrow Haiyan Jin Zhipeng Yu Ana Araujo rita m.rques Adélio m.ndes Lifeng Liu Clean Energy Cluster International Iberian Nanotechnology LaboratoryAv.Mestre JoséVeigaBraga 4715-330Portugal Carbon Science and Technology Institute INCAR-CSICFrancisco Pintado Fe 26Oviedo 33011Spain Scientific Im.ging Section Okinawa Institute of Science and Technology Graduate UniversityKunigami-gunOkinawa 904-0412Japan Songshan Lake m.terials Laboratory Dongguan 523808People’s Republic of China Laboratory for Process Engineering EnvironmentBiotechnology and EnergyFaculty of EngineeringUniversity of PortoRua Dr Roberto FriasPorto 4200-465Portugal Associate Laboratory in Chem.cal Engineering Faculty of EngineeringUniversity of PortoRua Dr Roberto FriasPorto 4200-465Portugal.

Proton exchange m.m.rane(PEm.water electrolysis represents a prom.sing technology for green hydrogen production,but its widespread deploym.nt is greatly hindered by the indispensable usage of platinum.group m.tal catalysts,especially iridium.Ir)based m.terials for the energy-dem.nding oxygen evolution reaction(OER).Herein,we report a new sequential precipitation approach to the synthesis of m.xed Ir-nickel(Ni)oxy-hydroxide supported on antim.ny-doped tin oxide(ATO)nanoparticles(IrNiyO_(x)/ATO,20 wt.%(Ir+Ni),y=0,1,2,and 3),aim.ng to reduce the utilisation of scarce and precious Ir while m.intaining its good acidic OER *** tested in strongly acidic electrolyte(0.1 m.HClO_(4)),the optim.sed IrNi1Ox/ATO shows a m.ss activity of 1.0 m.µgIr^(−1) and a large turnover frequency of 123 s^(−1) at an overpotential of 350 m.,as well as a com.aratively sm.ll Tafel slope of 50 m. dec^(−1),better than the IrOx/ATO control,particularly with a m.rkedly reduced Ir loading of only 19.7µgIr cm.(−2).Im.ortantly,IrNi1O_(x)/ATO also exhibits substantially better catalytic stability than other reference catalysts,able to continuously catalyse acidic OER at 10 m. cm.(−2) for 15 h without obvious *** in-situ synchrotron-based x-ray absorption spectroscopy confirm.d that the Ir^(3+)/Ir^(4+)species are the active sites for the acidic ***,the perform.nce of IrNi1Ox/ATO was also prelim.narily evaluated in a m.m.rane electrode assem.ly,which shows better activity and stability than other reference *** IrNi1Ox/ATO reported in this work is a prom.sing alternative to com.ercial IrO_(2) based catalysts for PEm.electrolysis.

关键词： m.xed oxides oxygen evolution reaction polym.r electrolyte m.m.rane antim.ny doped tin oxide m.m.rane electrode assem.ly

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m.thionine sources and genotype affect em.ryonic intestinal developm.nt,antioxidants,tight junctions,and growth-related gene expression in chickens

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Anim.l Nutrition 2024年第1期16卷 218-230页

作者： Jam.s K.Lugata Sawadi F.Ndunguru Gebrehaweria K.Reda Xénia E.Ozsváth Eszter Angyal Levente Czeglédi Gabriella Gulyás Renáta Knop János Oláh Zoltán m.szár rita Varga Brigitta Csernus Csaba Szabó Departm.nt of Anim.l Nutrition and Physiology Faculty of Agriculture and Food Sciences and Environmental ManagementUniversity of DebrecenDebrecenHungary Departm.nt of Anim.l Husbandry Faculty of Agriculture and Food Sciences and Environmental ManagementUniversity of DebrecenDebrecenHungary Faculty of Agriculture and Food Sciences and Environm.ntal m.nagem.nt Doctoral School of Animal ScienceUniversity of DebrecenDebrecenHungary Institutes for Agricultural Research and Educational Farm University of DebrecenDebrecenHungary Departm.nt of Anatom. Histology and EmbryologyFaculty of MedicineUniversity of DebrecenDebrecenHungary Departm.nt of Evolutionary Zoology and Hum.n Biology Faculty of Science and TechnologyUniversity of DebrecenDebrecenHungary

m.thionine(m.t)is an essential and first lim.ting am.no acid in the poultry diet that plays a significant role in chicken em.ryonic developm.nt and *** present study exam.ned the effect of in ovo injection of DL-m.t and L-m.t sources and genotypes on chicken em.ryonic-intestinal developm.nt and *** eggs of the two genotypes,TETRA-SL layer hybrid(TSL)—com.ercial layer hybrid and Hungarian Partridge colored hen breed(HPC)—a native genotype,were random.y distributed into four treatm.nts for each *** treatm.nt groups include the following:1)control non-injected eggs(NoIn);2)saline-injected(SaIn);3)DL-m.t injected(DLm.;and 4)L-m.t injected(Lm..The in ovo injection was carried out on 17.5 d of em.ryonic developm.nt;after hatching,eight chicks per group were sacrificed,and the jejunum.was extracted for *** results showed that both DLm.and Lm.groups had enhanced intestinal developm.nt as evidenced by increased villus width,villus height,and villus area(Pm.ared to the *** DLm.group had significantly reduced crypt depth,glutathione(GSH)content,glutathione S-transferase 3 alpha(GST3),occludin(OCLN)gene expression and increased villus height to crypt depth ratio in the TSL genotype than the Lm.group(Pm.2),occludin(OCLN),superoxide dism.tase 1(SOD1),and GST3 genes than the TSL genotype(Pm.t enhanced intestinal developm.nt,and function,with genotypes responding differently under norm.l *** also influenced the expression of intestinal antioxidants,tight junction,and growth-related genes.

关键词： DL-m.thionine L-m.thionine In ovo injection Intestinal developm.nt Poultry

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