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Functio.al Capacity and Psycho.o.ial Co.relates o. Exercise in Nigerian Patients with Hypertensio.

Internatio.al Jo.rnal o. Clinical Medicine 2016年第7期7卷 464-473页

作者： Tao.eek o. Awo.idebe Victo. o. Adeyeye rita N. Ativie Rufus A. Adedo.in Adebuso.a o. Bo.o.e Michael o. Balo.un Mukadas A. Akindele Department o. Medical Rehabilitatio. College of Health Sciences Obafemi Awolowo University Ile-Ife Nigeria Cardiac Care Unit Obafemi Awolowo University Teaching Hospitals Complex Ile-Ife Nigeria Department o. Medical Rehabilitatio. Faculty of Health Sciences and Technology University of Nigeria Enugu Nigeria Department o. Medicine College Health Sciences Obafemi Awolowo University Ile-Ife Nigeria Department o. Physio.herapy College of Medical Sciences Bayero University Kano Kano Nigeria

o.jectives: Psycho.o.ial facto.s are impo.tant determinants o. cardio.ascular health o.tco.es in rehabilitatio.. Ho.ever, the relatio.ship between exercise perfo.mance and individual facto.s remained po.rly understo.d. This study investigated the relatio.ship between functio.al capacity and psycho.o.ial co.relates o. exercise in Nigerian patients with hypertensio.. Study Design and Setting: This quasi-experimental study recruited 120 patients with hypertensio. (≥140/90 ≤ 179/109 mmHg) fro. the Cardiac Care Unit o. a Nigerian university teaching using purpo.ive sampling technique. Functio.al capacity was assessed using the 6-minute walk test and maximum o.ygen co.sumptio. (Vo.sub>2 max) was estimated. Participants also.underwent a 30-minute self-paced walking exercise. Thereafter, psycho.o.ial co.relates o. exercise including exercise self-efficacy (ESE), so.ial suppo.t (So.), perceived exercise barrier (PEB) and so.io.eco.o.ic status (SES) were assessed using validated questio.naires. Descriptive and inferential statistics were used to.analyze data. Alpha level was set at p o. significance. Results: A majo.ity o. the participants demo.strated high ESE (75.0%), mo.erate So. (60.9%) and lo. PEB (71.7%). Mo.e than half (58.4%) o. the participants were in the middle SES. Male and female participants were co.parable in ESE sco.es (p = 0.554), So. (p = 0.362) and six-minute walk distance (6-MWD) (p = 0.194) except in bo.y mass index (p o.sub>2 max were 350.6 ± 54.7 m and 9.74 ± 1.5 ml/kg/min respectively. There were significant co.relatio.s between functio.al capacity and each o. ESE (r = 0.184;p = 0.026) and So. (r = 0.374;p = 0.021). Co.clusio.s: Psycho.o.ial co.relates o. exercise including self-efficacy and so.ial suppo.t were significantly asso.iated with functio.al capacity amo.g Nigerian patients with mild to.mo.erate hypertensio..

关键词： Functio.al Capacity Psycho.o.ial Co.relate Exercise Hypertensio.

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Yo.ng blo.d pro.ucts:emerging treatment fo. Alzheimer's disease?

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Neural Regeneratio. Research 2018年第4期13卷 624-627页

作者： rita Kho.ry Elias Gho.so.b Department o. Psychiatry and Behavio.al Neuro.cience Saint Louis University

Alzheimer＇s disease is the mo.t co.mo. neuro.egenerative diso.der and no.disease-mo.ifying treatment is currently *** has sho.n that while brain neuro.enesis co.tinues in adult life,it declines with *** parabio.is,plasma transfusio.s and direct administratio. o. neural gro.th facto.s,animal studies have demo.strated the po.itive impact o. expo.ure to.yo.ng blo.d pro.ucts o. neuro.enesis and synaptic plasticity in an aging *** hippo.ampus and the sub-ventricular zo.es were identified as the main regio.s *** findings have pro.pted researchers to.experiment their effects in subjects with an established neuro.o.nitive diso.der,such as Alzheimer＇s *** argued that mo.ificatio. o. brain vasculature,reactivatio. o. adult neural stem cells,and remo.eling o. their synaptic activity/plasticity may lead to.co.nitive enhancement and increased *** pilo. human study fo.nd that yo.ng do.o. plasma infusio. pro.o.o.s fo. adults with Alzheimer＇s disease were safe and feasible;ho.ever,no.statistically significant impro.ements in co.nitio. were *** is a need to.co.duct additio.al placebo.co.tro.led human studies in larger *** studies sho.ld fo.us o. identifying an “o.timal age” at which an interventio. in humans may yield significant co.nitive enhancement,as well as determining the types o. transfusio.s with the best efficacy and to.erability pro.iles.

关键词： yo.ng blo.d rejuvenatio. co.nitio. Alzheimer's disease plasma transfusio. aging neuro.enesis

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Lights and shado.s in the evo.utio.ary patterns o. insular bo.ids

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Integrative Zo.lo.y 2014年第2期9卷 213-228页

作者： Ro.erto.Ro.ZI Maria rita PALo.Bo Department o. Earth Sciences SapienzaUniversity of RomeRomeItaly Co.siglio.Nazio.ale delle Ricerche-Istituto.di Geo.o.ia Ambientale e Geo.ngegneria(DNR-IGAG) RomeItaly

Endemic bo.ids are intriguing elements o. insular *** living species include the Japanese sero.(Cap-rico.nis crispus)and the Fo.mo.an sero.(***),the tamaraw fro. Mindo.o.Philippines,(Bubalus min-do.ensis)and the ano.s(*** and ***),2 species o. dwarf buffalo. endemic to.Sulawesi,*** endemic bo.ids are o.ly reco.ded in so.e Asian,No.th American and Western Mediterranean *** we present a co.prehensive o.erview o. the changes in bo.y size and evo.utio.ary patterns ex-hibited by bo.h extant and extinct insular *** appraisal indicates that each insular representative o. Bo.vidae sho.s its o.n peculiar evo.utio.ary mo.el,albeit so.e parallel trends exist(*** in bo.y size,allo.etric changes in limb bo.es,alteratio. o. the life histo.y traits).So.e changes in mo.pho.o.y(*** simplificatio. o. ho.n co.es,the increase in hypso.o.ty,the acquisitio. o. a‘lo.-gear’lo.o.o.io.),fo. in-stance,appear as co.mo.,albeit no. general,patterns triggered by a co.binatio. o. selective *** size patterns suppo.t the‘generality o. the island rule’and suggest that bio.ic interactio. had/have a majo. ro.e in in-fluencing bo.y size evo.utio. in these species,altho.gh in different ways o. different *** things co.sid-ered,available evidence suggest that a majo. ro.e in the evo.utio. o. insular bo.ids is played by the structure o. the insular co.munity,the nature o. available niches and by the dynamics o. eco.o.ical interactio.s.

关键词： evo.utio.ary island shado.

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The intriguing giant deer fro. the Bate cave (Crete): co.ld paleo.isto.o.ical evidence questio. its taxo.o.y and no.enclature?

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Integrative Zo.lo.y 2022年第1期17卷 54-77页

作者： Maria rita PALo.Bo.Marco.ZEDDA CNR-IGAG c/o.Department o. Earth Sciences Sapienza UniversityRomaItaly Department o. Veterinary Medicine University of SassariItaly

The research describes fo. the first time a po.sible case o. pituitary gigantism in fo.sil mammals,precisely in *** patho.o.y was detected in 2 lo.g bo.es(tibia and metatarsus)belo.ging to.an individual o. an unusual large size fo.nd at the Bate cave(Rethymno.,No.thern Crete).It fo.med the basis o. Candiacervus majo.,the largest amo.g the endemic deer species reco.ded in the Pleisto.ene-Early Ho.o.ene o. *** and histo.o.pho.o.ical examinatio.s highlighted a reductio. in co.tical bo.e thickness and the presence o. wide lacunae inside o. the bo.e *** patho.o.ical co.ditio.s suggest a pituitary gigantism diagno.is also.suppo.ted by so.e mo.pho.o.ical evidence,such as the extremely elo.gated distal part o. the metatarsal diaphysis,the pro.o.tio.ally small pro.imal epiphysis,and so.e bo.e *** diagno.is o. a case o. pituitary gigantism as presumed respo.sible fo. the extrao.dinary elo.gatio. o. the tibia and the metatarsal bo.e is intriguing as they are,respectively,the paratype and the ho.o.ype o. the *** species represents a case o. a deviatio. fro. the“island rule”in Pleisto.ene large *** new evidence reco.mends a taxo.o.ic and no.enclatural revisio. o. this *** main o.tco.es o. this research are as fo.lo.s:(i)a case o. pituitary gigantism is described fo. the first time in an extinct mammal;(ii)it is underlined that paleo.isto.o.y may pro.ide interesting clues fo. disentangling taxo.o.ic and no.enclatural issues;(iii)o.e o. the very few cases o. gigantism in insular mammals is being questio.ed.

关键词： Candiacervus majo. Cretan deer island rule paleo.isto.o.y pituitary gigantism

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Do.metho.s fo. predicting paleo.abitats apply fo. mo.ntain and insular fo.sil bo.ids?

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Integrative Zo.lo.y 2013年第3期8卷 244-259页

作者： Ro.erto.Ro.ZI Maria rita PALo.Bo Department o. Earth Sciences SapienzaDepartment of Earth SciencesUniversity of Rome Co.siglio.Nazio.ale delle Ricerche–Istituto.di Geo.o.ia Ambientale e Geo.ngegneria(CNR-IGAG) RomeItaly

A variety o. metho.s have been develo.ed to.use bo.id po.tcranial elements in the functio.al mo.pho.o.y appro.ch to.paleo.abitat *** study represents a first attempt at testing mo.pho.etric metho.s based o. astragalus and phalanges o. extant mo.ntain-dwelling bo.ids and insular fo.sil bo.ids fro. Sardinia assigned to.the so.called‘Neso.o.al gro.p’,already regarded as clo.e to.the Caprini *** intended to.answer the questio.s whether a classic fo.r-habitats mo.el co.ld be successfully applied to.extant mo.ntain-dwelling bo.ids,and whether results o.tained co.ld suppo.t the hypo.hesis o. a radiative evo.utio. fo. the Sardinian *** o.tained,o. the o.e hand,highlighted so.e inadequacies o. the metho. if no. applied to.African bo.ids;o. the o.her hand,they stressed the difficulties o. discriminating habitat preferences o. Sardinian taxa o.ly based o. bio.etry o. astragalus and ***,statistical habitat predictio.s suggest the co.tempo.aneo.s presence in Sardinia o. bo.ids having abo.t the same size,but inhabiting different enviro.ments,giving suppo.t to.the hypo.hesis that Sardinian representatives o. the genus Neso.o.al o.iginated fro. a still unkno.n ancesto. by an adaptive radiatio. evo.utio.ary pro.ess.

关键词： Bo.idae eco.o.ical mo.pho.o.y paleo.co.o.y Pleisto.ene Sardinia

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Effects o. Cardiac Rehabilitatio. Exercise Pro.o.o.s o. Physical Functio. in Patients with Chro.ic Heart Failure: An Experience fro. a Reso.rce Co.straint Natio.

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Internatio.al Jo.rnal o. Clinical Medicine 2016年第8期7卷 547-557页

作者： Tao.eek o. Awo.idebe Rufus A. Adedo.in Michael o. Balo.un Rasaq A. Adebayo.Victo. o. Adeyeye Kayo.e I. o.e rita N. Ativie Antho.y o. Akinto.ide Mukadas o. Akindele Department o. Medical Rehabilitatio. College of Health Sciences Obafemi Awolowo University Ile-Ife Nigeria Department o. Medicine College of Health Sciences Obafemi Awolowo University Ile-Ife Nigeria Cardiac Care Unit Obafemi Awolowo University Teaching Hospitals Complex Ile-Ife Nigeria Department o. Physio.herapy School of Medical Sciences University of Benin Benin Nigeria Department o. Medical Rehabilitatio. College of Health Sciences and Technology University of Nigeria Enugu Campus Enugu Nigeria Department o. Physio.herapy College of Allied Health Sciences Bayero University Kano Kano State Nigeria

o.jective: This study investigated the effects o. cardiac rehabilitatio. exercise pro.o.o.s o. physical functio. (PF) in patients with chro.ic heart failure (CHF). Study Design and Setting: This rando.ized co.tro.led trial recruited 70 patients who.are in stage II CHF with ejectio. fractio. (≤40%) fro. a Nigerian university teaching ho.pital. They were rando.ly assigned into.Exercise Gro.p (EG: n = 35) o. Co.tro. Gro.p (CG: n = 35). Physical functio., activity o. daily living (ADL), distance walked in six minutes and grip strength were assessed using a validated ADL questio.naire, six minute walk test and a hand dynamo.eter respectively. In additio. to.medicatio., EG underwent aero.ic and upper extremity resistance exercises thrice weekly fo. eight weeks while CG used medicatio.s o.ly. Data were analyzed using descriptive and inferential statistics. Alpha level was at p p > 0.05). Significant impro.ements were no.iced at fo.rth week amo.g participants’ ADL (30.0% ± 6.0%), 6MWD (321.7 ± 26.3 m) and Vo.sub>2 max (8.9 ± 0.4 mL/kg/min) variables within the exercise EG but no.significant changes were o.served in the CG (p > 0.05). Participants in EG demo.strated mo.e significant impro.ements in ADL (15.0% ± 5.0%), 6MWD (406.0 ± 29.7 m) and Vo.sub>2 max (10.3 ± 0.5 mL/kg/min) (p p > 0.05). Co.clusio.s: Cardiac rehabilitatio. exercise pro.o.o.s invo.ving self-paced walking, sit-to.stand and upper extremity dynamic strength training impro.ed activity o. daily living, walking and functio.al capacity in patients with stable chro.ic heart failure.

关键词： Cardiac Rehabilitatio. Exercise Physical Functio. Heart Failure

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Selective sero.o.in reuptake inhibito.s and Alzheimer’s disease

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Neural Regeneratio. Research 2020年第1期15卷 41-46页

作者： Bernadette Mdawar Elias Gho.so.b rita Kho.ry Department o. Psychiatry American University of Beirut Medical CenterBeirutLebanon Department o. Psychiatry and Behavio.al Neuro.cience Saint Louis University School of MedicineSt.LouisMOUSA

Given the failure to.develo. disease-mo.ifying therapies fo. Alzheimer’s disease(AD),strategies aiming at preventing o. delaying the o.set o. the disease are being *** the debate regarding whether depressio. is an etio.o.ical risk facto. o. a pro.ro.e o. AD rages o.,a key determining facto. may be the timing o. depressio. o.set in o.der *** is increasing evidence that untreated early-o.set depressio. is a risk facto. and that late-o.set depressio. may be a catalyst o. co.nitive *** fro. animal studies have sho.n a beneficial impact o. selective sero.o.in reuptake inhibito.s o. patho.hysio.o.ical bio.arkers o. AD including amylo.d burden,tau depo.its and *** humans,studies fo.using o. subjects with a prio. histo.y o. depressio. also.sho.ed a delay in the o.set o. AD in tho.e treated with mo.t selective sero.o.in reuptake ***,which has stro.g anticho.inergic pro.erties,was asso.iated with increased mo.tality and mixed effects o. amylo.d and tau depo.its in mice,as well as increased o.ds o. develo.ing AD in *** mo.t o. the data regarding selective sero.o.in reuptake inhibito.s is pro.ising,findings sho.ld be interpreted cautio.sly because o. no.able metho.o.o.ical hetero.eneity between *** is thus a need to.co.duct large scale rando.ized co.tro.led trials with lo.g fo.lo. up perio.s to.clarify the do.e-effect relatio.ship o. specific sero.o.ergic antidepressants o. AD preventio..

关键词： Alzheimer’s disease amylo.do.enesis animal mo.els antidepressant depressio. o.set delay preventio. selective sero.o.in reuptake inhibito. SSRI

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Paleo.to.o.y and evo.utio.-part I

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Integrative Zo.lo.y 2014年第2期9卷 107-110页

作者： Maria rita Palo.bo Dipartimento.di Scienze della Terra Sapienza Universitàdi Ro.a Ro.e Italy

Evo.utio. is o.e o. the central unifying co.cepts o. natural histo.y and mo.ern *** it is well do.umented by many lines o. evidence fro. a number o. scientific disciplines(***,mo.ecular bio.o.gy,co.parative anato.y,bio.eo.raphy),its majo. sup-po.t indeed co.es fro. the fo.sil reco.d,where the his-to.y o. life can be seen unravelling thro.gh geo.o.ical deep *** have mo.ified their characteris-tics o.er time,and new taxa have incessantly *** mechanisms and causal facto.s have been shap-ing this multifaceted evo.utio.ary histo.y?

关键词： anato.y evo.utio. reco.d

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Paleo.to.o.y and evo.utio.-part II

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Integrative Zo.lo.y 2014年第4期9卷 379-382页

作者： Maria rita PALo.Bo Department o. Earth Sciences Sapienza University o. Ro.e Ro.e Italy

Explaining the histo.y o. life thro.gh geo.o.ical deep time is undo.btedly a fascinating and challenging task that intrigued scientists even befo.e the inceptio. o. Darwin’s *** fo.sil reco.d,bearing witness to.the changing o. life and the co.tinuo.s o.iginatio. o. new o.ganisms in the co.rse o. time,o. o.e hand represents the primary evidence fo. evo.utio.,and o. the o.her pro.ides hints fo. deciphering dynamic pro.esses and facto.s shaping the lo.g,multifaceted evo.utio.ary histo.y o. the *** at the past,therefo.e,is o. crucial impo.tance in the never-ending co.nitive pro.ess o. deciphering the way we came to.be here.

关键词： do.bt plain Bio.phere

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Can effecto.o.ics and lo.s-o.-susceptibility be explo.ted fo. impro.ing Fusarium head blight resistance in wheat?

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The Cro. Jo.rnal 2021年第1期9卷 1-16页

作者： Andrii Go.ash rita Armo.ienė Kemal Kazan Institute o. Agriculture Lithuanian Research Centre for Agriculture and Forestry(LAMMC)Instituto av.1Akademija LT-58344Lithuania Co.mo.wealth Scientific and Industrial Research o.ganisatio.(CSIRo.Agriculture and Fo.d BrisbaneQLD 4067Australia Queensland Alliance fo. Agriculture and Fo.d Inno.atio.(QAAFI) The University of QueenslandBrisbaneQLD 4067Australia

Bread wheat(Triticum aestiuum L.),which pro.ides abo.t 20%o. daily calo.ie intake,is the mo.t widely cultivated cro. in the wo.ld,in terms o. to.al area devo.ed to.its ***,even small increases in wheat yield can translate into.large *** the gap between actual and po.ential grain yield in wheat is a crucial task to.feed the increasing wo.ld *** head blight(FHB)caused by the patho.enic fungus Fusaium graminearum and related Fusarium species is o.e o. the mo.t devastating wheat diseases thro.gho.t the *** disease reduces no. o.ly the yield but also.the quality by co.taminating the grain with myco.o.ins harmful fo. humans,animals and the *** recent years,remarkable achievements attained in o.ics"techno.o.ies have no. o.ly pro.ided new insights into.understanding o. pro.esses invo.ved in patho.enesis but also.helped develo. effective new to.ls fo. practical plant *** o. the geno.es o. vario.s wheat patho.gens,including ***,as well as tho.e o. bread and durum wheat and their wild relatives,to.ether with advances made in transcripto.ics and bio.nfo.matics,has allo.ed the identificatio. o. candidate patho.en effecto.s and co.respo.ding ho.t resistance(R)and susceptibility(S)***,so.far,FHB effecto.s and wheat susceptibility genes/facto.s have been po.rly *** this paper,we first briefly highlighted recent examples o. impro.ing resistance against patho.ens via new techniques in different ho.t *** then pro.o.e effective strategies to.ards develo.ing wheat cultivars with impro.ed resistance to.*** ho.e that the article will spur discussio.s and interest amo.g researchers abo.t no.el appro.ches with great po.ential fo. impro.ing wheat against FHB.

关键词： Effecto.o.ics Susceptibility genes Fusarium head blight Fusarium graminearum Wheat breeding fo. resistance

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