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The Journal of Biomedical Research 2016年第3期30卷 248-250页

作者： rinki Kumari Aruna Agrawal G.P.Dubey K.Ilango Praveen K Singh G.P.I.Singh Institute of Medical Sciences Banaras Hindu UniversityVaranasi-221005India Interdisciplinary School of Indian System of Medicine SRM University Kattankulathur Kancheepuram Dist-603203India Adesh University Barnala Road Bathinda-151109India

Dear Editor, Herbal medicines have been used for prevention and treatment of human diseases and promotion of healthy living. These medicines, often self medicated and consumed as concentrated extracts, are not strictly regulated. Considering their popular use and increasing safety concerns, thorough evaluations of their efficacy and safety are warranted to protect consumers from potential adverse effects. Toxicity tests （acute, sub- acute and chronic） using animals are widely applied to evaulate adverse effects of a drug and thereby determine its ＂No Observed Adverse Effect Level＂（NOAEL）.

关键词： Safety evaluation of a polyherbal formulation containing hydroalcoholic extracts of Hippophae salicifolia Nyctanthes arbor-tristis Ocimum tenuiflorum and Reinwardtia indica in rodents

Outcomes after robot-assisted laparoscopic radical prostatectomy

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Asian Journal of Andrology 2009年第1期11卷 94-99页

作者： Declan G. murphy Benjamin J. Challacombe Anthony J. Costello The Urology Centre Guy＇s ＆ St. Thomas ＇NHS Foundation Trust London SE1 9RT UK Department of Urology Royal Melbourne Hospital Melbourne VIC 3054 Australia

Robot-assisted laparoscopic radical prostatectomy （RALRP） using the da Vinci surgical system is now in widespread use in many countries where economic conditions allow the installation of this expensive technology. Controversy has surrounded the procedure since it was first performed in 2000, with many critics highlighting the lack of evidence to support its use. However, despite the lack of level I evidence, many large studies of patients have confirmed that the procedure is feasible and safe, with low morbidity. Available longer-term oncological data seem to show that outcomes from the robotic approach at least match those of traditional open radical prostatectomy. Functional outcomes also seem satisfactory, although randomized controlled trials are lacking. This paper reviews the current status of RALRP with respect to perioperative data and complications and oncologic and functional outcomes.

关键词： da Vinci laparoscopic outcomes prostate cancer radical prostatectomy robotic

Reproductive Behavior and Underwater Calls in the Emei Mustache Toad,Leptobrachium boringii

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Asian Herpetological Research 2011年第4期2卷 199-215页

作者： Yuchi ZHENG Dingqi RAO Robert W.murphy Xiaomao ZENG Department of Herpetology Chengdu Institute of BiologyChinese Academy of Sciences Key Laboratory of Zoological Systematics and Evolution Institute of ZoologyChinese Academy of Sciences State Key Laboratory of Genetic Resources and Evolution Kunming Institute of ZoologyChinese Academy of Sciences Centre for Biodiversity and Conservation Biology Royal Ontario Museum100 Queen’s ParkToronto M5S 2C6OntarioCanada

The Emei mustache toad, Leptobrachium boringii （Megophryidae）, is terrestrial but breeds in permanent streams. Primarily, it has a polygynous mating system and polyandry also occurs. The species vigorously defends submerged nest sites. We report on a reproductive study at Mt. Emei, western China conducted in 2004, 2006, 2007, 2009, and 2011 during the breeding season. Males produce both advertisement and courtship calls underwater, and the latter differs from the former in having an additional trill-like last note of low intensity. Females might determine the oviposition location and hence the egg mass location. A low, submissive posture can be adopted by the male to avoid being attacked by other males. When fighting, the maxillary nuptial spines are employed as weapons, and males hold their opponents on their spines with the forelimbs that enlarge during the breeding season. Male body size and the quantity of fight wounds on its ventral side are positively correlated. Satellite male mating might exist in L. boringii. Additionally, underwater calls from another population of this species and a population of L. leishanense generally are similar to those of the population from Mt. Emei.

关键词： advertisement call courtship call underwater call male combat male weaponry nest inspection satellite male reproductive tactic

Targeting gut microbiota in hepatocellular carcinoma: probiotics as a novel therapy

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Hepatobiliary Surgery and Nutrition 2018年第1期7卷 11-20页

作者： murphy L.Y.Wan Hani El-Nezami School of Biological Sciences Faculty of ScienceThe University of Hong KongPokfulamHong KongChina Institute of Public Health and Clinical Nutrition University of Eastern FinlandKuopioFinland

Hepatocellular carcinoma(HCC),the most common primary liver cancer,is one of the dreaded complications of chronic liver *** experimental and clinical studies have revealed that the alteration of gut-liver axis plays a pivotal role in the onset of chronic liver diseases,including *** gut microbiota and endotoxemia are increasingly recognized as critical components in promoting the progression of chronic liver diseases to *** have been suggested as a novel,safe and cost-effective approach to prevent or treat *** by which probiotics exerts their anti-cancer effects include their ability to bind carcinogens,modulation of gut microbiota,improvement of intestinal barrier function,and *** review summarizes the literature findings of the changes in gut microbiota linked to HCC,and discusses the possible therapeutic implications of probiotics for HCC.

关键词： Endotoxemia gut-liver axis gut microbiota hepatocellular carcinoma(HCC) probiotics

Distribution Control Centers in the US and Europe:Commonalities,Differences,and Lessons

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Journal of Modern Power Systems and Clean Energy 2022年第2期10卷 259-268页

作者： Subramanian Vadari Izudin Dzafic Dan'l Koch Ryan murphy Daniel Hayes Jr. Tarik Donlagic Modem Grid Solutions New YorkUSA University of Sarajevo Faculty of Electrical EngineeringSarajevoBosnia and Herzegovina R.murphy are with Puget Sound Energy BellevueUSA Commonwealth Edison ChicagoUSA Siemens AG ErlanglenGermany

The distribution control center(DCC)has evolved from a sideshow in the traditional distribution service center to a major centerpiece of the utility moving into the decentralized ***,this is the place where much of the action is happening due to new forms of energy that are coining into the distribution *** creates the flexibility of operation and in-creased complexity due to the need for increased coordination between the transmission control center and ***,the US and European utilities have adapted to this change in very different ***,we describe the research works done in a DCC and their evolutions from the perspectives of major US utilities,and those enhanced by the European perspective focusing on the coordination of distribution system operator and transmission system operator(DSO-TSO).We pres-ent the insights into the systems used in these control centers and the role of vendors in their *** this paper,we present the perspectives of challenges,operational capabilities,and the involvement of various parties who will be re-sponsible to make the transition *** differences are pointed out on how distribution operations are conducted between the US and Europe.

关键词： Distribution control center(DCC) power system operation distributed generation asset flexibility volt-var optimization and control.

Guest editorial-special issue on ground control in mining in 2019

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International Journal of Mining Science and Technology 2020年第1期30卷 1-2页

作者： Michael M.murphy Ted Klemetti Heather Lawson Brijes Mishra Kyle Perry Pittsburgh Mining Research Division NIOSHPittsburghPA 15228USA Spokane Mining Research Division NIOSHSpokaneWA 99207USA Mining Engineering West Virginia UniversityMorgantownWV 26506USA Mining&Nuclear Engineering Missouri S&TRollaMO 65409USA

Ground control is the science of studying and controlling the behavior of rock strata in response to mining ***-control-related research has seen significant advancements over the last 39 years,and these accomplishments are well documented in the proceedings of the annual International Conference on Ground Control in Mining(ICGCM)[1].The ICGCM is a forum to promote closer communication among researchers,consultants,regulators,manufacturers,and mine operators to expedite solutions to ground control problems in mining[2–7].Fundamental research and advancements in ground control science define the central core of the conference *** information to mine operators is a priority,as the conference goal is to offer solutions-oriented *** addition,the conference has included innovative technologies and ideas in miningrelated fields such as exploration,geology,and surface and underground mining in all *** new ground control technologies and design standards adopted by the mining industry were first discussed at ***,this conference is recognized as the best international forum for introducing new groundcontrol-related research and products.

关键词： operators closer accomplishment

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The young Victoria

The young Victoria

Seven Things We Think We Know about Auxin Transport

作者： Deirdre murphy.

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Molecular Plant 2011年第3期4卷 487-504页

作者： Wendy Ann Peer Joshua J. Blakeslee Haibing Yang Angus S. murphy Department of Horticulture 625 Agriculture Mall Drive Purdue University West Lafayette IN 47907 USA Department of Horticulture and Crop Science Ohio Agricultural Researd and Development Center1680 Madison Avenue The Ohio State UniversityWooster OH 44691 USA

Polar transport of the phytohormone auxin and the establishment of localized auxin maxima regulate em- bryonic development, stem cell maintenance, root and shoot architecture, and tropic growth responses. The past decade has been marked by dramatic progress in efforts to elucidate the complex mechanisms by which auxin transport regulates plant growth. As the understanding of auxin transport regulation has been increasingly elaborated, it has become clear that this process is involved in almost all plant growth and environmental responses in some way. However, we still lack information about some basic aspects of this fundamental regulatory mechanism. In this review, we present what we know （or what we think we know） and what we do not know about seven auxin-regulated processes. We discuss the role of auxin transport in gravitropism in primary and lateral roots, phototropism, shoot branching, leaf expansion, and venation. We also discuss the auxin reflux/fountain model at the root tip, flavonoid modulation of auxin transport processes, and outstanding aspects of post-translational regulation of auxin transporters. This discussion is not meant to be exhaustive, but highlights areas in which generally held assumptions require more substantive validation.

关键词： Auxin transport ABCB AUX1 PIN phototropism gravitropism fountain model shoot branching leaf expansion venation flavonoids.

Guest editorial-special issue on ground control in mining in 2018

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International Journal of Mining Science and Technology 2019年第1期29卷 1-2页

作者： Michael M.murphy Ted Klemetti Heather Lawson Brijes Mishra Kyle Perry Pittsburgh Mining Research Division NIOSH Spokane Mining Research Division NIOSH Mining Engineering West Virginia University Mining&Nuclear Engineering Missouri S&T

Ground control is the science of studying and controlling the behavior of rock strata in response to mining operations. Ground control-related research has seen significant advancements over the last 37 years, and these accomplishments are well documented in the proceedings of the annual International Conference on Ground Control in Mining (ICGCM)(1)The ICGCM is a forum to promote closer communication among researchers, consultants。

关键词： NIOSH Guest editorial-special issue on ground control in mining in 2018

Trial by fire:Testing the paleolongitude of Pangea of competing reference frames with the African LLSVP

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Geoscience Frontiers 2020年第4期11卷 1253-1256页

作者： Ross N.Mitchell Lei Wu J.Brendan murphy Zheng-Xiang Li State Key Laboratory of Lithospheric Evolution Institute of Geology and GeophysicsChinese Academy of SciencesBeijingChina Earth Dynamics Research Group The Institute for Geoscience Research(TIGeR)School of Earth and Planetary SciencesCurtin UniversityGPO Box U1987PerthWAAustralia Department of Earth Sciences St.Francis Xavier UniversityAntigonishNova ScotiaCanada

Paleogeography can be reconstructed using various crust-or mantle-based reference frames that make fundamentally different *** various reconstruction models differ significantly in continental paleolongitude,but it has been difficult to assess which models are more *** suggest here a "LLSVP test",where an assumed correlation between present-day large low velocity shear-wave provinces and the paleogeography of supercontinent Pangea at breakup ca.200 million years ago can be used to assess the relative accuracy of published *** correlations between continental paleolongitude and the African LLSVP are achieved with mantle-based reference frames(moving hotspots and true polar wander),whereas shallower crustbased reference frames are shown to be *** relative success of mantle-based frames,and thus the importance of the depth of reference frame,supports the notion that mantle convection is largely vertical compared to the horizontal plate motion of tectonics.

关键词： Palaeogeography Plate tectonics LLSVPs Reference frames