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Exploring the Current Practices,Costs and Benefits of FAIR Implementation in Pharmaceutical Research and Development:A Qualitative Interview Study

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Data Intelligence 2021年第4期3卷 507-527页

作者： Ebtisam Alharbi rigina skeva Nick Juty Caroline Jay Carole Goble School of Computer Science University of ManchesterManchesterManchester M139PLUK College of Computer and Information Systems Umm Al-Qura UniversityMeccaMakkah 21421Saudi Arabia

The findable,accessible,interoperable,reusable(FAIR)principles for scientific data management and stewardship aim to facilitate data reuse at scale by both humans and *** and development(R&D)in the pharmaceutical industry is becoming increasingly data driven,but managing its data assets according to FAIR principles remains costly and *** date,little scientific evidence exists about how FAIR is currently implemented in practice,what its associated costs and benefits are,and how decisions are made about the retrospective FAIRification of data sets in pharmaceutical R&*** paper reports the results of semi-structured interviews with 14 pharmaceutical professionals who participate in various stages of drug R&D in seven pharmaceutical *** thematic analysis identified three primary themes of the benefits and costs of FAIRification,and the elements that influence the decision-making process for FAIRifying legacy data *** collectively acknowledged the potential contribution of FAIRification to data reusability in diverse research domains and the subsequent potential for *** costs,however,were still considered a barrier by participants,with the need for considerable expenditure in terms of resources,and cultural *** decisions were made about FAIRification was influenced by legal and ethical considerations,management commitment,and data *** findings have significant implications for those in the pharmaceutical R&D industry who are engaged in driving FAIR implementation,and for external parties who seek to better understand existing practices and challenges.

关键词： FAIR FAIRification Retrospective FAIRification Pharmaceutical R&D Cost-benefit Decision-making process

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