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Journal of Otology 2024年第1期19卷 5-9页

作者： Cameron B.Fattahi Christopher Zaro Janice J.Chung richard F.lewis Divya A.Chari Department of Otolaryngology-Head and Neck surgery UMASS Memorial Medical CenterUniversity of Massachusetts Chan Medical SchoolWorcesterMAUSA Jenks Vestibular Physiology Laboratory Massachusetts Eye and EarBostonMAUSA Department of Otolaryngology-Head and Neck surgery Massachusetts Eye and EarHarvard Medical SchoolBostonMAUSA Department of Neurology Harvard Medical SchoolBostonMAUSA

Background: Bithermal caloric irrigation, video head impulse test(vHIT), and rotational testing are commonly used to assess peripheral vestibular function, but the relative clinical utility of each test in differentiating patients with peripheral vestibulopathy is ***: To determine whether(1) the combination of two or more vestibular tests enhances diagnostic utility over a single test;(2) abnormal test results on vestibular tests correlate with one ***: Retrospective analysis of data collected from multidisciplinary vestibular clinics at two academic medical centers from 2016 to ***: 150 patients(54.10 ± 15.09 years, 88 females) were included. No individual test was significantly better at predicting the presence of peripheral vestibular damage(p > 0.05). vHIT test results improved significantly when combined with either the caloric test(p = 0.007) or rotary chair test(p = 0.039). Caloric and rotational testing had high sensitivity(74.65% and 76.06%, respectively) and specificity(83.54% and 78.48%, respectively). vHIT demonstrated excellent specificity(89.87%) but poor sensitivity(47.89%). Caloric, vHIT, and rotary chair tests results did not correlate with one another(p > 0.05).Conclusions: Vestibular function tests have comparable diagnostic utility, yet each offers unique advantages. Caloric and rotational testing may be best suited for screening peripheral damage and vHIT may function ideally as a confirmatory test.

关键词： vestibular patients specificity

Bound and Resonating Multiquark Configurations

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Chinese Physics Letters 2024年第8期41卷 8-12页

作者： Jean-Marc richard Institut de Physique des 2 Infinis de Lyon Université Claude Bernard(Lyon 1) CNRS-IN2P34 rue Enrico Fermi69622 VilleurbanneFrance

We review the predictions of quark models for multiquark configurations that are bound or resonant states,and compare different methods for estimating the properties of resonances.

关键词： quark Configuration resonant

RecBERT:semantic recommendation engine with large language model enhanced query segmentation for k-nearest neighbors ranking retrieval

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Intelligent and Converged Networks 2024年第1期5卷 42-52页

作者： richard Wu the Dublin Unified school District and the sF Artificial Intelligence Club DublinCA 94568USA

The increasing amount of user traffic on Internet discussion forums has led to a huge amount of unstructured natural language data in the form of user *** modern recommendation systems rely on manual tagging,relying on administrators to label the features of a class,or story,which a user comment corresponds *** common approach is to use pre-trained word embeddings to compare class descriptions for textual similarity,then use a distance metric such as cosine similarity or Euclidean distance to find top k ***,neither approach is able to fully utilize this user-generated unstructured natural language data,reducing the scope of these recommendation *** paper studies the application of domain adaptation on a transformer for the set of user comments to be indexed,and the use of simple contrastive learning for the sentence transformer fine-tuning process to generate meaningful semantic embeddings for the various user comments that apply to each *** order to match a query containing content from multiple user comments belonging to the same class,the construction of a subquery channel for computing class-level similarity is *** channel uses query segmentation of the aggregate query into subqueries,performing k-nearest neighbors(KNN)search on each individual *** achieves state-of-the-art performance,outperforming other state-of-the-art models in accuracy,precision,recall,and F1 score for classifying comments between four and eight classes,*** outperforms the most precise state-of-the-art model(distilRoBERTa)in precision by 6.97%for matching comments between eight classes.

关键词： sentence transformer simple contrastive learning large language models query segmentation k-nearest neighbors

Near-infrared Emissive 1,2-Dioxetane-based Chemiluminescent Probes

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CHEMICAL REsEARCH IN CHINEsE UNIVERsITIEs 2024年第5期40卷 806-823页

作者： Chen, Yingqi Budianta, richard Ning, Yingying south China Univ Technol Spin X Inst Sch Chem & Chem Engn Sch Biomed Sci & EngnState Key Lab Luminescent Ma Hong Kong 510641 Guangdong Peoples R China

Chemiluminescence, a phenomenon emitting light from chemical reactions rather than photon absorption, has gained significant interest for applications in bioimaging and biosensing due to its high sensitivity and low background interference. Now there is a growing interest in near-infrared (NIR) chemiluminescent probes for improved tissue penetration and reduced autofluorescence. This review summarizes NIR emissive chemiluminescent probes based on 1,2-dioxetane and discusses their chemical structures and applications. structure modification strategies for red-shifting wavelength and enhancing brightness include incorporating electron-withdrawing groups, designing chemiluminophore-fluorophore cassettes, and exploring alternative chemiluminescent scaffolds. This review aims to inspire the exploration of NIR chemiluminescent probes in disease detection and treatment.

关键词： Chemiluminescence Near-infrared Dioxetane Bioimaging Biosensing REsONANCE ENERGY-TRANsFER ELECTRON-EXCHANGE LUMINEsCENCE AGGREGATION-INDUCED EMIssION BICYCLIC DIOXETANEs BEARING IN-VIVO PHOTODYNAMIC THERAPY sINGLET-OXYGEN TRANsFER CAssETTEs BIOLUMINEsCENCE GENERATION

Parameter-Free shifted Laplacian Reconstruction for Multiple Kernel Clustering

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IEEE/CAA Journal of Automatica sinica 2024年第4期11卷 1072-1074页

作者： Xi Wu Zhenwen Ren F.richard Yu the school of National Defence science and Technology Southwest University of Science and TechnologyMianyang 621010China the school of National Defence science and Technology Southwest University of Science and TechnologyMianyang 621010 the Guangxi Key Laboratory of Machine Vision and Intelligent Control Wuzhou UniversityWuzhou 543002 the Guangdong Laboratory of Artificial Intelligence and Digital Economy(sZ) Shenzhen 518060China

Dear Editor,This letter proposes a parameter-free multiple kernel clustering(MKC)method by using shifted Laplacian *** MKC can effectively cluster nonlinear data,but it faces two main challenges:1)As an unsupervised method,it is up against parameter problems which makes the parameters intractable to tune and is unfeasible in real-life applications;2)Only considers the clustering information,but ignores the interference of noise within Laplacian.

关键词： parameter letter Parameter

Liver transplantation as an alternative for the treatment of non-resectable liver colorectal cancer: Advancing the therapeutic algorithm

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Hepatobiliary & Pancreatic Diseases International 2024年第2期23卷 154-159页

作者： Badi Rawashdeh richard Bell Abdul Hakeem Raj Prasad Division of Transplant surgery Department of General SurgeryMedical College of WisconsinMilwaukeeWI53226USA Leeds Teaching Hospital LeedsUK

Colorectal cancer is a leading cause of cancerrelated mortality,with nearly half of the affected patients developing liver *** three decades,liver resection(LR)has been the primary curative strategy,yet its applicability is limited to about 20%of *** transplantation(LT)for unresectable metastases was attempted unsuccessfully in the 1990s,with high rates of perioperative death and *** is now more interest in this strategy due to improvements in systemic therapies and surgical techniques.A significant study conducted by the Oslo group showed that patients receiving liver transplants had a 60%chance of survival after five *** better results have been achieved by using advanced imaging for risk stratification and further refining selection criteria,especially in the Norvegian sECA *** review carefully charts the development and history of LT as a treatment option for colorectal cancer liver *** revolutionary path from the early days of exploratory surgery to the current situation of cautious optimism is traced,highlighting the critical clinical developments and improved patient selection standards that have made LT a potentially curative treatment for such challenging very well selected cases.

关键词： Liver transplantation Colorectal cancer liver metastases Non-resectable liver metastases

New analytical modelling of fractional generalized Kuramoto-sivashinky equation via Atangana-Baleanu operator and J-transform method

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Journal of Ocean Engineering and science 2024年第1期9卷 66-88页

作者： Metonou richard Weidong Zhao shehu Maitama school of Mathematics Shandong UniversityJinanShandongChina

In this paper,we propose a new analytical modelling of the well-known fractional generalized Kuramoto-sivashinky equation(FGKsE)using fractional operator with non-singular kernel and the homotopy anal-ysis transform method via J-transform ***,using fixed-point theorem,we prove the existence and uniqueness of our proposed solution to the fractional Kuramoto-sivashinky *** further val-idate the efficiency of the suggested technique,we proved the convergence analysis of the method and provide the error *** obtained solutions of the FGKsE,describing turbulence processes in the field of ocean engineering are analytically and numerically compared to show the behaviors of many parameters of the present model.

关键词： Homotopy analysis J-transform method J-transform method Fractional generalized Kuramoto-sivashinky equation Fixed-point theorem Numeric-symbolic computation

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混凝土自复位墙结构地震全过程损伤分析

建筑结构学报 2024年第2期45卷 189-204页

作者：鲁懿虬 HENRY richard s 周颖 RODGERs Geoffrey W 杨群顾安琪同济大学土木工程学院上海200092 奥克兰大学土木与环境系新西兰奥克兰1010 坎特伯雷大学土木与自然资源工程系新西兰基督城8140

后张法预应力混凝土自复位墙是一种有效的可恢复功能结构。虽然自复位墙自身在地震中损伤较小,但其与周边构件的变形不协调可使结构损伤严重。为控制结构层面的损伤,设计了1个框架-自复位墙结构,对自复位墙底、梁柱节点、墙梁节点、墙-... 详细信息

后张法预应力混凝土自复位墙是一种有效的可恢复功能结构。虽然自复位墙自身在地震中损伤较小,但其与周边构件的变形不协调可使结构损伤严重。为控制结构层面的损伤,设计了1个框架-自复位墙结构,对自复位墙底、梁柱节点、墙梁节点、墙-基础连接、柱-基础连接以及墙-板连接开展损伤控制设计,并对设计的结构进行足尺振动台试验。结构共经历了39次不同设计工况下不同烈度的地震激励,峰值加速度最大达1.0g,位移角最大达3.3%。对结构在历次地震作用下整体、局部构件和节点的损伤发展进行全过程定量分析,结果表明:自复位墙-开槽梁结构在地震作用下的损伤能够得到有效控制,其中多遇、设防地震作用下结构基本无损伤,罕遇地震作用下墙底损伤仅限角部剥落且面积仅为400 cm2,楼板有开裂且裂缝最大仅为1.2 mm,梁端剥落可忽略;自复位墙-开槽梁结构可使整个结构在不同设计位移角下实现多遇、设防地震不坏,罕遇地震小修甚至不修的抗震性能目标;设计的连接方式解决了结构中构件之间的变形不协调问题,提高了自复位墙结构层面的可修复性。

关键词：自复位墙开槽梁墙板连接振动台试验结构损伤

Amino acid and mineral digestibility,bone ash,and plasma inositol is increased by including microbial phytase in diets for growing pigs

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Journal of Animal science and Biotechnology 2024年第2期15卷 699-712页

作者： Liz Vanessa Lagos Mike richard Bedford Hans Henrik stein Division of Nutritional sciences University of IllinoisUrbanaIL 61801USA AB Vista Marlborough SN84ANUK

Background The effect of microbial phytase on amino acid and energy digestibility is not consistent in pigs,which may be related to the phytase dosage or the adaptation length to the ***,an experiment was conducted to test the hypotheses that increasing dietary phytase after an 18-day adaptation period:1)increases nutrient and energy digestibility;2)increases plasma P,plasma inositol,and bone ash of young pigs;and 3)demonstrates that maximum phytate degradation requires more phytase than maximum P *** Data indicated that increasing inclusion of phytase[0,250,500,1,000,2,000,and 4,000 phytase units(FTU)/kg feed]in corn-soybean meal-based diets increased apparent ileal digestibility(AID)of Trp(quadratic;Ps and Thr(linear;Pse AID of Met(linear;Psing dietary phytase also increased AID and apparent total tract digestibility(ATTD)of Ca and P(quadratic;Psed ATTD of K and Na(linear;Pse did not influence the ATTD of Mg or gross *** of plasma P and bone ash increased(quadratic;Psma inositol also increased(linear;Psing inclusion of *** concentrations of inositol phosphate(IP)6 and IP5(quadratic;Psed inositol concentrations(linear;Pserved in ileal digesta as dietary phytase *** ATTD of P was maximized if at least 1,200 FTU/kg were used,whereas more than 4,000 FTU/kg were needed to maximize inositol *** Increasing dietary levels of phytase after an 18-day adaptation period increased phytate and IP ester degradation and inositol release in the small ***,increasing dietary phytase resulted in improved digestibility of Ca,P,K,Na,and the first 4 limiting amino acids,and in increased concentrations of bone ash and plasma P and *** a corn-soybean meal diet,maximum inositol release requires appr

关键词： Bone ash Inositol Nutrient digestibility Phytase Phytate degradation Pigs