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Management and Outcomes in Primary Tumors of the Appendix

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Journal of Cancer Therapy（癌症治疗） 2010年第4期

作者： richard k. englehardt Noreen k. Durrani Vijay k. Mittal

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Management and Outcomes in Primary Tumors of the Appendix

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Journal of Cancer Therapy 2010年第4期1卷 174-180页

作者： englehardt richard Durrani Noreen Mittal Vijay Department of Surgery Providence Hospital and Medical Centers SouthfieldMIUSA Department of Surgery Providence Hospital and Medical Centers SouthfieldMIUSA.

Primary tumors of the appendix are rare, comprising 1.1% of all appendectomy specimens. Nevertheless, it often presents in an emergent fashion, creating a need for a well-defined management algorithm that will ensure proper acute management. We performed a retrospective review of medical charts from 1982-2007 on all charts with a diagnosis of appendiceal neoplasm. A cohort of 41 patients was diagnosed with a primary appendiceal neoplasm from a total of 8560 appendectomies over the 25-year period. Several tumors were identified: adenocarcinomas (n = 16), carcinoid tumors (n = 15), mucinous cystadenocarcinoma (n = 7), and a combination of adenocarcinoma and goblet cell carcinoid of the appendix (n = 3). Twenty-one patients presented with an acute abdomen. Tumors were discovered intraoperatively in eighteen patients while performing other procedures. At diagnosis, metastatic disease was found in 41.5% of patients (n = 17);average survival ranged from 6 to 21 months based on tumor type. For patients with non-metastatic disease at diagnosis, all survived longer than 2 years and there were no cases of recurrence or post-operative metastasis. We devised an operative strategy dictated by initial presenting characteristics of the tumor. The presence of carcinoma should be suspected and searched for in patients over 40 presenting with acute appendicitis. Intraoperatively any suspicious mass should undergo frozen sectioning as the finding of a malignancy often necessitates a larger or repeat operation. The propensity of these neoplasms for presentation in the guise of acute appendicitis mandates that the surgeon be familiar with the appropriate management algorithm, both in and out of the operating room.

关键词： Appendix Cancer Gastrointestinal Malignancy Malignant Neoplasms of the Appendix

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These "thin partitions"

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作者： edited by Joshua D. englehardt and Ivy A. Rieger.

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作者： (美)Lisa H. Newton (美)Elaine Eliason englehardt (美)Michael Pritchard

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Risk. of iron deficiency among vegetarian college women

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Health 2012年第3期4卷 113-119页

作者： Susan N. Hawk.k.mberly Grage englehardt Cindi Small Department of Food Science and Nutrition California Polytechnic State University San Luis Obispo USA Department of Nutrition Health and Exercise Science Central Washington University Ellensburg USA

Iron deficiency anemia is the most common nutritional deficiency disease worldwide and poses a major threat in women of child-bearing age and those who follow a vegetarian diet. The objective of this study was to ascertain whether differences exist in iron status mark.rs between female university students following a vegetarian and non-vegetarian diet. This study took.a cross sectional analysis of 39 female students at California Polytechnic State University (Cal Poly State University) in San Luis Obispo, CA between the ages of 18 and 22. Of the participants, 19 followed a vegetarian diet and 20 followed a nonvegetarian diet. Characteristic, demographic, and anthropometric data were collected and analyzed. The results showed no significant difference in iron intak. between the two groups. However, nearly 66% of vegetarians and 65% of non-vegetarians failed to meet the Recommended Daily Allowance for iron. No significant difference was found for serum iron, serum ferritin, transfer-rin saturation, and total iron binding capacity between subjects. Serum ferritin tended to be lower for vegetarians compared to non-vegetarians. Both vegetarians and non-vegetarians were in stage IV negative iron balance, with more vegetarians tending to be in stage IV negative iron balance than non-vegetarians. Thus, female college students, irrespective of their meat intak., may be at higher risk.of developing negative iron balance and should be educated about iron deficiency anemia and the prevention of iron depletion.

关键词： Iron Anemia Vegetarian Negative Iron Balance

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Risk. of iron deficiency among vegetarian college women

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Health（健康） 2012年第3期

作者： Susan N. Hawk.k.mberly Grage englehardt Cindi Small

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