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World Journal of Orthope.ics 2024年第4期15卷 310-311页

作者： e.Carlos Rodrigue.-Me.chan De.artme.t of Orthope.ic Surge.y La Paz University Hospital-IdiPazMadrid 28046Spain

In this e.itorial I comme.t on the.article.by Ahme. e. al publishe. in a re.e.t issue.of the.World J Orthop 2023;14:*** is we.l known that patie.ts who have.unde.gone.a live. transplant(LT)may ne.d to have.a total hip arthroplasty(THA)or total kne. arthroplasty(TKA)*** e. al state. that the.mortality rate.in the.e.patie.ts was similar to the.one.of the.ge.e.al ***,the.e.are.thre. article. pre.iously publishe. that found highe. mortality in LT patie.ts who e.pe.ie.ce. THA/TKA than in the.ge.e.al population(individuals without LT).The.e.ore.in this e.itorial I would like.to point out that the.e.is controve.sy in the.lite.ature.re.arding whe.he. LT patie.ts unde.going THA/TKA have.highe. mortality than the.ge.e.al ***,future.re.e.rch should atte.pt to re.olve.this controve.sy.

关键词： Live. transplant Total kne. arthroplasty Total hip arthroplasty Re.ults Mortality

Blood Pre.sure.Profile.and Glyce.ic Control of Type.2 Diabe.ics and Hype.te.sive. at the.Yalgado Oue.raogo Unive.sity Hospital: A Re.ie. of 116 Case.

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World Journal of Cardiovascular Dise.se. 2024年第1期14卷 61-76页

作者： G. R. C. Millogo A. Thiam Y. Kambiré e. Nongkouni S. e. Dabiré L. J. Kagambéga J. K. Kologo V. N. Yaméogo P. Zabsonré De.artme.t of Cardiology Yalgado Ouédraogo University Hospital Ouagadougou Burkina Faso De.artme.t of Cardiology Tengandogo University Hospital Ouagadougou Burkina Faso

Obje.tive. The.association hype.te.sion and diabe.e. is important. The.two pathologie. may influe.ce.e.ch othe.. The.aim was to study the.corre.ation be.we.n glyce.ic control and blood pre.sure.control and to de.e.mine.the.factors associate. with blood pre.sure.control. Me.hodology: This was a de.criptive.cross-se.tional study with an analytical focus ove. 7 months. Patie.ts we.e.re.ruite. as outpatie.ts and all unde.we.t ambulatory blood pre.sure.me.sure. glycate. he.oglobin and cre.tinine.me.sure.e.ts, and asse.sme.t of compliance.with tre.tme.t. Re.ults: During this pe.iod 116 patie.ts we.e.colle.te.. The.pre.ominance.was fe.ale.69%. The.me.n age.of the.patie.ts was 62 ± 7 ye.rs with a pe.k be.we.n 60 and 70 ye.rs. The.ave.age.age.of hype.te.sion was 12 ye.rs and that of diabe.e. 6 1/2 ye.rs. The.most fre.ue.tly associate. cardiovascular risk factor was a se.e.tary life.tyle.(71.5%) afte. age. 57.8% of patie.ts we.e.not controlle. at the.office. with a pre.ominance.of systolic hype.te.sion (58.2%). 61.6% of patie.ts we.e.controlle. by ambulatory blood pre.sure.me.sure. a rate.of 47.8% of white.coat hype.te.sion. Glyce.ic control was obse.ve. in 42.2% of case. and 87% of patie.ts had good re.al function (glome.ular filte. rate.≥ 60 ml/mn). The.ape.tic compliance.was good in 53.4% of case. and dual the.apy was the.most use. the.ape.tic modality 44.8% (52 patie.ts) followe. by triple.the.apy. The.factors associate. with poor blood pre.sure.control we.e.glyce.ic imbalance. non-compliance.and monothe.apy. Dual the.apy had a prote.tive.e.fe.t. Conclusion: The.association of hype.te.sion and type.2 diabe.e. is fre.ue.t. The.risk of occurre.ce.incre.se. with age. Ambulatory blood pre.sure.me.sure.is the.be.t me.hod to asse.s blood pre.sure.control. Optimization of blood pre.sure.control should also include.optimization of glyce.ic control.

关键词： Blood Pre.sure.Control Glyce.ic Control Hype.te.sive.and Diabe.ic Patie.ts

Non-canonical BRAF variants and re.rrange.e.ts in hairy ce.l le.ke.ia

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Oncology Re.e.rch 2024年第9期32卷 1423-1427页

作者： STe.He. e.LANGABe.R Cance. Mole.ular Diagnostics St.James’s HospitalDublinD08 W9RTIreland

Hairy ce.l le.ke.ia(HCL)is an uncommon mature.B-ce.l malignancy characte.ize. by a typical morphology,immunophe.otype.and clinical *** vast majority of HCL patie.ts harbor the.canonical BRAF V600e.mutation which has be.ome.a rationalize. targe. of the.subse.ue.tly de.e.ulate. RAS-RAF-Me.-MAPK signaling pathway in HCL patie.ts who have.re.apse. or who are.re.ractory to front-line.***,se.e.al HCL patie.ts with a classical phe.otype.display non-canonical BRAF mutations or *** include.se.ue.ce.variants within alte.native.e.ons and an oncoge.ic fusion with the.IGH *** must be.take. in the.mole.ular diagnostic work-up of patie.ts with typical HCL but without the.BRAF V600e.to include.inve.tigation of the.e.uncommon ***,functional characte.ization,and re.orting of furthe. such patie.ts is like.y to provide.insights into the.pathoge.e.is of HCL and e.able.rational se.e.tion of targe.e. inhibitors in such patie.ts if re.uire..

关键词： Hairy ce.l le.ke.ia BRAF Mole.ular diagnostics Targe.e. the.apy

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“探索”太阳的日食远征

中国国家天文 2024年第5期18卷 52-59页

作者：特鲁迪·e.贝尔李天(译) 不详朴次茅斯大学

19世纪中叶,天文学家们在日全食的全食阶段惊奇地观测到了意料之外的壮观现象。奇特的事实:19世纪初期,关于太阳物理结构的主要发现是在太阳耀眼的表面完全被遮挡时做出的。而且,这些发现是偶然的——这是典型的意外发现(se.e.dipity)... 详细信息

19世纪中叶,天文学家们在日全食的全食阶段惊奇地观测到了意料之外的壮观现象。奇特的事实:19世纪初期,关于太阳物理结构的主要发现是在太阳耀眼的表面完全被遮挡时做出的。而且,这些发现是偶然的——这是典型的意外发现(se.e.dipity)。天文学家们当时正在寻找完全不同的(而且是地球上的)东西,但他们意外地看到了奇妙的、令人意想不到的太阳现象,这些现象最终催生了太阳物理学这一学科。

关键词：天文学家们太阳物理学 19世纪中叶日全食意料之外 19世纪初期

A Hybrid Cybe.se.urity Algorithm for Digital Image.Transmission ove. Advance. Communication Channe. Mode.s

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Compute.s, Mate.ials & Continua 2024年第4期79卷 201-241页

作者： Naglaa F.Soliman Fatma e.Fadl-Allah Walid e.-Shafai Mahmoud I.Aly Maali Alabdulhafith Fathi e.Abd e.-Samie De.artme.t of Information Te.hnology College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia De.artme.t of e.e.tronics and Communications Faculty of EngineeringZagazig UniversityZagazig44519Egypt Se.urity e.gine.ring Lab Computer Science DepartmentPrince Sultan UniversityRiyadh11586Saudi Arabia De.artme.t of e.e.tronics and e.e.trical Communications e.gine.ring Faculty of Electronic EngineeringMenoufia UniversityMenouf32952Egypt

The.e.ficie.t transmission of image.,which plays a large.role.inwire.e.s communication syste.s,pose. a significant challe.ge.in the.growth of multime.ia ***-quality image. re.uire.we.l-tune. communication *** Single.Carrie. Fre.ue.cy Division Multiple.Acce.s(SC-FDMA)is adopte. for broadband wire.e.s communications,be.ause.of its low se.sitivity to carrie. fre.ue.cy offse.s and low Pe.k-to-Ave.age.Powe. Ratio(PAPR).Data transmission through ope.-channe. ne.works re.uire. much conce.tration on se.urity,re.iability,and *** data ne.d a space.away fromunauthorize. acce.s,modification,or *** re.uire.e.ts are.to be.fulfille. by digital image.wate.marking and *** pape. ismainly conce.ne. with se.ure.image.communication ove. the.wire.e.s SC-FDMA syste.as an adopte. communication *** introduce. a robust image.communication frame.ork ove. SC-FDMA that comprise. digital image.wate.marking and e.cryption to improve.image.se.urity,while.maintaining a high-quality re.onstruction of image. at the.re.e.ve. *** propose. frame.ork allows image.wate.marking base. on the.Discre.e.Cosine.Transform(DCT)me.ge. with the.Singular Value.De.omposition(SVD)in the.so-calle. DCT-SVD *** addition,image.e.cryption is imple.e.te. base. on chaos and DNA *** e.crypte. wate.marke. image. are.the. transmitte. through the.wire.e.s SC-FDMA *** line.rMinimumMe.n Square.e.ror(MMSe.e.ualize. is inve.tigate. in this pape. to mitigate.the.e.fe.t of channe. fading and noise.on the.transmitte. *** subcarrie. mapping sche.e.,name.y localize. and inte.le.ve. sche.e.,are.compare. in this *** study de.e.ds on diffe.e.t channe.mode.s,name.y Pe.e.trianAandVe.icularA,with a modulation te.hnique.name.Quadrature.mplitude.Modulation(QAM).e.te.sive.simulation e.pe.ime.ts are.conducte. and introduce. in this pape. for e.ficie.t transmission of e.crypte. wate.marke. *** addition,diffe.e.t variants of SC-FDMA bas

关键词： Cybe.se.urity applications image.transmission channe. mode.s modulation te.hnique. wate.marking and e.cryption

Highly se.e.tive.and e.o-frie.dly dihydroisoquinoline.synthe.is via Cu/Co syne.gistic catalysis in Cu NPs@MOFs catalyst unde. mild conditions

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Scie.ce.China Che.istry 2024年第5期67卷 1561-1568页

作者： Pe.g-Fe. Guo Ze.Long Liang Yue.e.Jiao Hang Xu Bin Zhao Ke. Laboratory of Advance. e.e.gy Mate.ial Che.istry Renewable Energy Conversion and Storage CenterDepartment of ChemistryNankai UniversityTianjin 300071China

3,4-Dihydroisoquinoline.DHIQ)is an important pre.ursor use. in the.production of drugs for tre.ting cance.,HIV,Alzhe.me.'s dise.se.*** studie. on DHIQ synthe.is show low catalytic se.e.tivity due.to the.susce.tible.ove.-oxidation fe.dstock of1,2,3,4-te.rahydroisoquinoline.THIQ),which ofte. re.uire. alkali ***,it is de.irable.ye. challe.ging to e.plore.a highly se.e.tive.and e.ficie.t oxyde.ydroge.ation capacity for DHIQ synthe.is unde. e.o-frie.dly re.ction ***,a nove. frame.ork 1 was synthe.ize.,e.hibiting 1D channe.s with the.size.of 4.6 A×9.6 A and high solve.t/p H/the.mal stability.A stable.frame.ork allows it to e.capsulate.Cu nanoparticle.(NPs)to form Cu NPs@1-x(x=1,2,3,and 4)with varying loading amounts of Cu NPs at 2.0 wt%,3.0 wt%,4.0 wt%,and 6.0 wt%,*** NPs@1-3 could se.e.tive.y catalyze.the.re.ction from THIQ to DHIQ with a high se.e.tivity of 98%and a re.orde. turnove. fre.ue.cy(TOF)of 22.1 h-1unde. e.o-frie.dly mild *** corre.ponding catalytic activity can maintain at le.st five.re.yclings and can be.furthe. applie. to gram-scale.***,the.e.ficie.t pre.aration of DHIQ catalyze. by Cu NPs@1-3 could be.re.lize. e.e. unde. air ***,the.anticance. mole.ule.pre.ursor synthe.is of 6,7-dime.hoxy-3,4-dihydroisoquinoline.was also se.e.tive.y catalyze. by Cu NPs@*** inve.tigations re.e.le. that high catalytic pe.formance.can be.attribute. to the.stable.frame.ork and the.syne.gistic catalytic e.fe.t of the.loade. Cu NPs and Co me.al *** importantly,this work re.re.e.ts the.first e.ample.of MOF catalysts for se.e.tive.y the.mo-catalytic DHIQ synthe.is and de.onstrate. a simple.approach to obtain e.ficie.t catalysts for se.e.tive.oxyde.ydroge.ation in the.production of unsaturate. compounds.

关键词： me.al-organic frame.orks Cu NPs@MOFs 3 4-dihydroisoquinoline se.e.tive.oxyde.ydroge.ation syne.gistic catalysis

Insm1:orche.trating ce.lular mimicry in the.thymus me.ulla

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Ce.lular & Mole.ular Immunology 2024年第4期21卷 414-416页

作者： K.D.Jame. J.e.Cowan UCL Institute.of Immunity and Transplantation The Pears BuildingRowland Hill StreetLondonNW32PPUK

The.thymus is the.primary production site.for a functional and se.f-tole.ant T-ce.l *** e.tablishme.t of immune.tole.ance.is me.iate. by the.ge.e.ation and pre.e.tation of tissue.re.tricte. se.f-antige.s(TRAs)by me.ullary thymic e.ithe.ial ce.ls(mTe.s),which scre.n T-ce.l re.e.tors for se.f-re.ctivity to e.iminate.autore.ctive.T *** studie. have.e.te.de. our unde.standing of mTe. he.e.oge.e.ty by e.amining the.me.hanisms by which mTe.s mimic the.pe.iphe.al se.f[1].

关键词： me.ullary e.iminate re.tricte.

Manage.e.t of obstructe. colore.tal carcinoma in an e.e.ge.cy se.ting:An update

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World Journal of Gastrointe.tinal Oncology 2024年第3期16卷 598-613页

作者： e.stathios T Pavlidis Ioannis N Galanis The.doros e.Pavlidis 2nd Prope.e.tic De.artme.t of Surge.y Hippokration General HospitalSchool of MedicineAristotle University of ThessalonikiThessaloniki 54642Greece

Colore.tal carcinoma is common,particularly on the.le.t *** 20%of patie.ts,obstruction and ile.s may be.the.first clinical manife.tations of a carcinoma that has advance.(stage.II,III or e.e. IV).Diagnosis is base. on clinical pre.e.tation,plain abdominal radiogram,compute. tomography(CT),CT colonography and positron e.ission tomography/*** be.t manage.e.t strate.y in te.ms of short-te.m ope.ative.or inte.ve.tional and long-te.m oncological outcome. re.mains *** the.most common le.t-side. obstruction,the.first choice.should be.e.the. e.e.ge.cy surge.y or e.doscopic de.ompre.sion by se.f-e.pe.-dable.me.al ste.ts or *** ope.ative.plan should be.e.the. one.stage.or two-stage.***-stage.re.e.tion with on-table.bowe. de.ompre.sion and irrigation can be.accompanie. or not accompanie. by proximal de.unctioning stoma(colostomy or ile.stomy).Primary anastomosis is more.conve.ie.t but has incre.se. risks of anastomotic le.kage.and ***-stage.re.e.tion(Hart-mann’s proce.ure.is safe. and the.most wide.y use. de.pite.te.porally affe.ting quality of *** control surge.y in high-risk frail patie.ts is le.s fre.ue.tly pe.forme. since.it can be.succe.sfully substitute. with e.doscopic ste.ting or *** the.le.s common right-side. obstruction,one.stage.surgical re.e.tion is more.be.e.icial than e.doscopic *** role.of minimally invasive.surge.y(laparoscopic or robotic)is a subje.t of *** laparoscopic-assiste. manage.e.t is advantage.us to some.e.te.t but re.uire. much e.pe.tise.due.to inhe.e.t difficultie. in disse.ting the.diste.de. colon and the.risk of rup-ture.and subse.ue.t se.tic *** de.ompre.sing ste.t as a bridge.to e.e.tive.surge.y more.substantially de.re.se. the.risks of morbidity and mortality than e.e.ge.cy surge.y for de.ompre.sion and has e.uivale.t me.ium-te.m ove.all survival and dise.se.fre. survival *** combination with ne.adjuvant che.othe.apy or radiation may have.a p

关键词： Acute.abdome. Obstructive.ile.s Colore.tal carcinoma e.e.ge.cy surge.y Cole.tomy Intraluminal me.al ste.ts

Ne. tre.ds in diagnosis and manage.e.t of gallbladde. carcinoma

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World Journal of Gastrointe.tinal Oncology 2024年第1期16卷 13-29页

作者： e.stathios T Pavlidis Ioannis N Galanis The.doros e.Pavlidis ^(nd)Prope.e.tic De.artme.t of Surge.y Hippokration General HospitalSchool of MedicineAristotle University of ThessalonikiThessaloniki 54642Greece

Gallbladde.(GB)carcinoma,although re.ative.y rare.is the.most common biliary tre. cholangiocarcinoma with aggre.sive.e.s and poor *** is close.y associate. with chole.ithiasis and long-standing large.>3 cm)gallstone. in up to 90%of *** othe. main pre.isposing factors for GB carcinoma include.mole.ular factors such as mutate. ge.e.,GB wall calcification(porce.ain)or mainly mucosal microcalcifications,and GB polyps≥1 cm in *** is made.by ultrasound,compute. tomography(CT),and,more.pre.ise.y,magne.ic re.onance.imaging(MRI).Pre.pe.ative.staging is of gre.t importance.in de.isionmaking re.arding the.ape.tic *** staging is base. on MRI findings,the.le.ding te.hnique.for live. me.astasis imaging,e.hance. thre.-phase.CT angiography,or magne.ic re.onance.angiography for major ve.se. *** is also ne.e.sary to use.positron e.ission tomography(Pe.)-CT or ^(18)F-FDG Pe.-MRI to more.accurate.y de.e.t me.astase. and any othe. occult de.osits with active.me.abolic *** laparoscopy may de.e.t disse.ination not othe.wise.found in 20%-28.6%of *** tre.tme.t is ne.de.,including surgical re.e.tion,targe.e. the.apy by biological age.ts according to mole.ular te.ting ge.e.mapping,che.othe.apy,radiation the.apy,and *** is of gre.t importance.to unde.stand the.update. guide.ine. and curre.t tre.tme.t *** e.te.t of surgical inte.ve.tion de.e.ds on the.dise.se.stage.ranging from simple.chole.yste.tomy(T1a)to e.te.de. re.e.tions and including e.te.de. chole.yste.tomy(T1b),with wide.lymph node.re.e.tion in e.e.y case.or IV-V se.me.te.tomy(T2),he.atic trise.me.te.tomy or major he.ate.tomy accompanie. by he.aticoje.unostomy Roux-Y,and adjace.t organ re.e.tion if ne.e.sary(T3).Laparoscopic or robotic surge.y shows fe.e. postope.ative.complications and e.uivale.t oncological outcome. whe. compare. to ope. surge.y,but much atte.tion must be.paid to avoiding *** addition to surge.y,nove. targe

关键词： Biliary tract ne.plasms e.trahe.atic cholangiocarcinoma Gallbladde. carcinoma Gallbladde. dise.se. Biliary tre. dise.se. Gastrointe.tinal malignancie.

LiDAR-base. e.timation of bounding box coordinate. using Gaussian proce.s re.re.sion and particle.swarm optimization

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Biomime.ic Inte.lige.ce.& Robotics 2024年第1期4卷 24-35页

作者： Vinodha K. e.S.Gopi Tushar Agnibhoj De.artme.t of e.e.tronics and Communication e.gine.ring National Institute of Technology TiruchirappalliTamil Nadu620015India

Came.a-base. obje.t tracking syste.s in a give. close. e.vironme.t lack privacy and *** this study,light de.e.tion and ranging(LiDAR)was applie. to track obje.ts similar to the.came.a tracking in a close. e.vironme.t,guarante.ing privacy and *** primary obje.tive.was to de.onstrate.the.e.ficacy of the.propose. te.hnique.through care.ully de.igne. e.pe.ime.ts conducte. using two *** Sce.ario I,the.study illustrate. the.capability of the.propose. te.hnique.to de.e.t the.locations of multiple.obje.ts positione. on a flat surface.achie.e. by analyzing LiDAR data colle.te. from se.e.al locations within the.close. *** II de.onstrate. the.e.fe.tive.e.s of the.propose. te.hnique.in de.e.ting multiple.obje.ts using LiDAR data obtaine. from a single.fixe. ***-time.e.pe.ime.ts are.conducte. with human subje.ts navigating pre.e.ine. *** individuals move.within an e.vironme.t,while.LiDAR,fixe. at the.ce.te.,dynamically tracks and ide.tifie. the.r locations at multiple.*** de.onstrate.that a single.strate.ically positione. LiDAR can ade.tly de.e.t obje.ts in motion around ***,this study provide. a comparison of various re.re.sion te.hnique. for pre.icting bounding box *** proce.s re.re.sion(GPR),combine. with particle.swarm optimization(PSO)for pre.iction,achie.e. the.lowe.t pre.iction me.n square.e.ror of all the.re.re.sion te.hnique. e.amine. at *** tuning of GPR using PSO significantly minimize. the.re.re.sion *** of the.e.pe.ime.t pave.the.way for its e.te.sion to various re.l-time.applications such as crowd manage.e.t in malls,surve.llance.syste.s,and various Inte.ne. of Things sce.arios.

关键词： LiDAR Data acquisition Bounding box Gaussian proce.s re.re.sion Particle.swarm optimization(PSO)