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Multi-Elemental Chemostratigraphy,Sequence Development,Depositional History,and Environmental Importance of Early Eocene Red Beds(Kuldana Formation)in NW Himalayas,Pakistan

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Journal of Earth Science 2024年第2期35卷 349-375页

作者： Amir Shahzad George Kontakiotis Thierry Adatte Khawaja Shoaib ahmed Muhammad Tayyib riaz Hammad Tariq Janjuhah Evangelia Besiou Institute of Geology University of Azad Jammu and KashmirMuzaffarabad13100Pakistan Department of Historical Geology-Paleontology Faculty of Geology and GeoenvironmentSchool of Earth SciencesNational and Kapodistrian University of AthensPanepistimiopolisZografou15784Greece Institute of Earth Sciences(ISTE) University of LausanneLausanneCH-1015Switzerland Department of Geology Shaheed Benazir Bhutto UniversitySheringalPeshawar18050Pakistan

The Eocene Kuldana Formation(KF)in the Yadgar area of Pakistan,comprises a diverse range of sedimentary facies,including variegated red beds of shales,mudstones,and sandstones,as well as interbedded limestone and *** this study,we conducted an integrated micropaleontological,sedimentological,mineralogical,and geochemical investigation to determine the depositional setting,biochronology,provenance,and paleoclimate of the *** study identified six lithofacies and six microfacies,which indicate a variety of environments ranging from floodplains and channels to the margins and shallow marine *** nannofossil biostratigraphy places the KF in the Early Eocene,more precisely the NP10 zone(Ypresian),and the fossil zone of benthic foraminifera classifies the study section as the Shallow Benthic Zone SBZ-8(Middle Ilerdian 2).In terms of petrography,the KF sandstone was classified as litharenite and feldspathic litharenite,while the QtFL diagram suggests a recycled *** proxies indicate an oxidizing environment,a high-to-low regular sedimentation rate,moderate-to-intense chemical weathering in the source region,and a warm-humid to dry climate during the deposition of ***,the findings suggest that the deposition of KF marks the end of Neo-Tethys due to the Early Eocene Indian–Kohistan collision and that the uplifting of the Himalayas provided the source for the deposition of KF in the foreland *** study provides new insights into the depositional environment,biochronology,provenance,and paleoclimate of KF,and highlights the potential for red beds as reliable indicators of oxygenation levels in proximity to mineral deposits.

关键词： sedimentary microfacies Paleocene–Eocene thermal maximum stratigraphic correlations paleoenvironmental reconstruction nannofossils paleontology

Strategies to enhance cottonseed oil contents and reshape fatty acid profile employing different breeding and genetic engineering approaches

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Journal of Integrative Agriculture 2019年第10期18卷 2205-2218页

作者： Iram Sharif Jehanzeb Farooq Shahid Munir Chohan Sadaf Saleem riaz Ahmad kainth Abid Mahmood Ghulam Sarwar Cotton Research Station Faisalabad 38000Pakistan Ayub Agricultural Research Institute Faisalabad 38000Pakistan

Cottonseed oil is the valuable byproduct extracted after seed cotton processing for lint. It confers a huge contribution to total vegetable oil production and ranked the 2nd to meet global edible oil requirements. Over centuries, breeders mainly focused to improve lint production and fiber quality. Now attention has been given to improve the cottonseed oil percentage, its functional and nutritional properties. However, these efforts are less than other major oilseed crops which left cottonseed oil market behind in term of consumer demand and kept cott on seed oil industry at vuln erable positi on. Con siderable progress has been made to alter the relative percentage of fatty acid composition still intensified efforts have been required to meet the global oilseed demand. The objective of this review is to explore the cotton germplasm variation for seed oil carrying potential, its utilization in suitable breeding programs, seed oil biosynthetic pathways, major genes, and QTLs linked to quantity and quality enhancement of oil and deployment of modern genomic tools, viz., gene silencing and transgenic development to ameliorate its nutritional properties.

关键词： biosynthesis edible oil gene silencing oil quality oleic acid stearic acid

A Hybrid Duo-Deep Learning and Best Features Based Framework for Action Recognition

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Computers, Materials & Continua 2022年第11期73卷 2555-2576页

作者： Muhammad Naeem Akbar Farhan riaz ahmed Bilal Awan Muhammad Attique Khan Usman Tariq Saad Rehman National University of Sciences and Technology(NUST) Islamabad46000Pakistan Department of Computer Science HITEC UniversityTaxilaPakistan College of Computer Engineering and Science Prince Sattam Bin Abdulaziz UniversityAl-Kharaj 11942Saudi Arabia

Human Action Recognition(HAR)is a current research topic in the field of computer vision that is based on an important application known as video *** in computer vision have introduced various intelligent methods based on deep learning and machine learning,but they still face many challenges such as similarity in various actions and redundant *** proposed a framework for accurate human action recognition(HAR)based on deep learning and an improved features optimization algorithm in this *** deep learning feature extraction to feature classification,the proposed framework includes several critical *** training fine-tuned deep learning models–MobileNet-V2 and Darknet53–the original video frames are *** feature extraction,pre-trained deep models are used,which are fused using the canonical correlation *** that,an improved particle swarm optimization(IPSO)-based algorithm is used to select the best *** that,the selected features were used to classify actions using various *** experimental process was performed on six publicly available datasets such as KTH,UT-Interaction,UCF Sports,Hollywood,IXMAS,and UCF YouTube,which attained an accuracy of 98.3%,98.9%,99.8%,99.6%,98.6%,and 100%,*** comparison with existing techniques,it is observed that the proposed framework achieved improved accuracy.

关键词： Action recognition deep learning features fusion features selection recognition

Metabolic alterations in cancer cells and therapeutic implications

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Chinese Journal of Cancer 2011年第8期30卷 508-525页

作者： Naima Hammoudi Kausar Begam riaz ahmed1 Celia Garcia- Prieto Peng Huang Department of Molecular Pathology The University of Texas MD Anderson Cancer Center Houston Texas 77030 USA The University of Texas Graduate School of Biomedical Sciences at Houston Houston Texas 77030 USA The Department of Health Disparities Research The University of Texas MD Anderson Cancer Center. Houston. Texas 77030. USA.

Cancer metabolism has emerged as an important area of research in recent *** of the metabolic differences between cancer and normal cells and the underlying mechanisms will not only advance our understanding of fundamental cancer cell biology but also provide an important basis for the development of new therapeutic strategies and novel compounds to selectively eliminate cancer cells by targeting their unique *** article reviews several important metabolic alterations in cancer cells,with an emphasis on increased aerobic glycolysis (the Warburg effect) and glutamine addiction,and discusses the mechanisms that may contribute to such metabolic *** addition,metabolic alterations in cancer stem cells,mitochondrial metabolism and its influence on drug sensitivity,and potential therapeutic strategies and agents that target cancer metabolism are also discussed.

关键词：新陈代谢肿瘤细胞治疗细胞生物学药物敏感性正常细胞谷氨酰胺代谢变化

Lifestyle behaviours of immigrant and Australian children:Evidence from a nationally representative sample

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Sports Medicine and Health Science 2022年第2期4卷 112-118页

作者： Shahnawaz ahmed riaz Uddin Jenny Ziviani Sjaan Gomersall Asaduzzaman Khan School of Health and Rehabilitation Sciences The University of QueenslandBrisbaneAustralia Institute for Physical Activity and Nutrition(IPAN) Deakin UniversityGeelongAustralia

This study aimed to examine the prevalence of physical activity(PA),screen time(ST),sleep,and fruit and vegetable intake of children with low-and-middle-income countries(LMIC)parents,high-income countries(HIC),and Australian children,and whether these behaviours are associated with their immigrant *** for this study were from wave 7 of the Birth cohort(B cohort)of the Longitudinal Study of Australian *** used generalized estimating equations(GEE)to examine associations between health behaviours and immigrant *** models were adjusted for a number of *** with LMIC parents had lower odds of meeting PA and sleep recommendations and higher odds ratio(OR)of meeting fruit and vegetable intake,and ST recommendations than Australian or HIC *** with LMIC parents had one-third the odds of meeting the PA recommendations(OR 0.39[95%CI 0.22–0.70])than Australian *** significant differences were observed in lifestyle behaviours among children with HIC parents and Australian *** behaviours of children with LMIC parents differed from those of HIC and Australian ***,children with HIC parents and Australian children had comparable lifestyle *** disparities in lifestyle behaviours among immigrant children can inform strategies to bring equity in Australian children's *** study underscores the importance of culturally appropriate targeted interventions to promote PA and sleep of children with LMIC parents.

关键词： Physical activity Screen time Sleep Fruit Vegetable HIC LMIC

Potential medicinal plants involved in inhibiting 3CL^(pro) activity:A practical alternate approach to combating COVID-19

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Journal of Integrative Medicine 2022年第6期20卷 488-496页

作者： Fan Yang Xiao-lan Jiang Akash Tariq Sehrish Sadia Zeeshan ahmed Jordi Sardans Muhammad Aleem riaz Ullah Rainer W.Bussmann The Medical Center of General Practice Sichuan Academy of Medical Science and Sichuan Provincial People’s HospitalChengdu 610041Sichuan ProvinceChina Xinjiang Institute of Ecology and Geography Chinese Academy of SciencesUrumqi 830041Xinjiang Uygur Autonomous RegionChina Department of Biological Sciences University of Veterinary and Animal SciencesRavi CampusPattoki 55300Pakistan Consejo Superior de Investigaciones Científicas Global Ecology UnitCentre for Ecological Research and Forestry Applications-Consejo Superior de Investigaciones Científicas-Universitat Autònoma de BarcelonaBellaterra08193 BarcelonaCataloniaSpain Centre for Ecological Research and Forestry Applications Cerdanyola del Vallès 08193CataloniaSpain Department of Pharmacognosy College of PharmacyKing Saud UniversityRiyadh 11451Saudi Arabia Department of Ethnobotany Institute of Botanyllia State UniversityTbilisi 0105Georgia

At present,a variety of vaccines have been approved,and existing antiviral drugs are being tested to find an effective treatment for coronavirus disease 2019(COVID-19).However,no standardized treatment has yet been approved by the World Health *** virally encoded chymotrypsin-like protease(3CL^(pro))from severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),which facilitates the replication of SARS-CoV in the host cells,is one potential pharmacological target for the development of antiSARS *** search engines,such as Web of Science,Google Scholar,Scopus and PubMed,were used to retrieve data on the traditional uses of medicinal plants and their inhibitory effects against the SARS-CoV 3CL^(pro).Various pure compounds,including polyphenols,terpenoids,chalcones,alkaloids,biflavonoids,flavanones,anthraquinones and glycosides,have shown potent inhibition of SARS-CoV-2 3CL^(pro) activity with 50% inhibitory concentration(IC_(50))values ranging from 2-44μg/***,most of these active compounds,including xanthoangelol E(isolated from Angelica keiskei),dieckol 1(isolated from Ecklonia cava),amentoflavone(isolated from Torreya nucifera),celastrol,pristimerin,tingenone and iguesterin(isolated from Tripterygium regelii),tannic acid(isolated from Camellia sinensis),and theaflavin-3,3’-digallate,3-isotheaflav1in-3 gallate and dihydrotanshinone I(isolated from Salvia miltiorrhiza),had IC_(50)values of less than 15μg/*** mechanistic studies of several active compounds revealed that their mode of inhibition was dose-dependent and competitive,with K_(i)values ranging from 2.4-43.8μmol/*** the significance of plant-based compounds and the many promising results obtained,there is still need to explore the phytochemical and mechanistic potentials of plants and their *** medicinal plants could serve as an effective inexpensive nutraceutical for the general public to help manage COVID-19.

关键词： COVID-19 SARS-CoV-2 Coronavirus 3C proteases Medicinal plants Plant-derived compounds Drug development

Design and Development of Low-cost Wearable Electroencephalograms (EEG) Headset

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Intelligent Automation & Soft Computing 2023年第3期35卷 2821-2835页

作者： riaz Muhammad ahmed Ali M.Abid Anwar Toufique ahmed Soomro Omar AlShorman Adel Alshahrani Mahmoud Masadeh Ghulam Md Ashraf Naif H.Ali Muhammad Irfan Athanasios Alexiou Department of Electrical Engineering Sukkur IBA University65200SukkurPakistan Department of Electronic Engineering Quaid-e-Awam University of EngineeringScience and TechnologyLarkana77150Pakistan Faculty of Engineering and AlShrouk Trading Company Najran UniversityNajran61441Saudi Arabia Department of Medical Rehabilitation Sciences-Physiotherapy Program College of Applied Medical SciencesNajran UniversityNajran61441Saudi Arabia Computer Engineering Department Yarmouk UniversityIrbid21163Jordan Pre-Clinical Research Unit King Fahd Medical Research CenterKing Abdulaziz UniversityJeddah21589Saudi Arabia Department of Medical Laboratory Technology Faculty of Applied Medical SciencesKing Abdulaziz UniversityJeddah21589Saudi Arabia Department of Internal Medicine Medical CollegeNajran UniversityNajran61441Saudi Arabia Electrical Engineering Department College of EngineeringNajran University Saudi ArabiaNajran61441Saudi Arabia Novel Global Community Educational Foundation HebershamNSW 2770AustraliaAFNP Med AustriaWien2770Austria

Electroencephalogram(EEG)is a method of capturing the electrophy-siological signal of the *** EEG headset is a wearable device that records electrophysiological data from the *** paper presents the design and fab-rication of a customized low-cost Electroencephalogram(EEG)headset based on the open-source OpenBCI Ultracortex Mark IV *** electrode placement locations are modiﬁed under a 10–20 standard *** fabricated headset is then compared to commercially available headsets based on the following para-meters:affordability,accessibility,noise,signal quality,and ***,the data is recorded from 20 subjects who used the EEG Headset,and signals were ***,the participants marked the accuracy,set up time,participant comfort,and participant perceived ease of set-up on a scale of 1 to 7(7 being excellent).Thirdly,the self-designed EEG headband is used by 5 participants for slide *** raw EEG signal is decomposed into a series of band sig-nals using discrete wavelet transform(DWT).Lastly,theseﬁndings have been compared to previously reported *** concluded that when used for slide-changing control,our self-designed EEG headband had an accuracy of 82.0 *** also concluded from the results that our headset performed well on the cost-effectiveness scale,had a reduced setup time of 2±0.5 min(the short-est among all being compared),and demonstrated greater ease of use.

关键词： Brain-computer interface EEG consumer-grade accessibility headset

One-pot Synthesis,Characterization and Crystal Structure Determination of Novel 1,4,5-Trisubstituted 1,2,3-Triazole with Two Conformational Isomers:1-Benzyl-5-((4-methoxyphenyl)ethynyl)-4-phenyl-1H-1,2,3-triazole

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Chinese Journal of Structural Chemistry 2016年第1期35卷 55-60页

作者： ahmed Muhammad Naeem YASIN Khawaja Ansar KHAN Bilal Ahmad riaz Muhammad SADIQ-UR-REHMAN LO Kong Mun NASEER Muhammad Moazzam ARSHAD Ifzan IRSHAD Muhammad Department of Chemistry The University of Azad Jammu and Kashmir Department of Chemistry University of Malaya Department of Chemistry Quaid-i-Azam University Department of Chemistry University of Poonch Rawalakot Azad Kashmir

The title compound l-benzyl-5-（（4-methoxyphenyl）ethynyl）-4-phenyl-1H-1,2,3-triazole（C24H19N3O） was designed and synthesized using one-pot strategy and structural characterization was done by single-crystal X-ray diffraction,NMR,IR and *** compound was crystallized out from an ethanolic solution in triclinic system,space group P1 with a =9.9038（9）,b = 10.2928（9）,c = 18.8715（19）A°,α = 103.541（6）,β = 90.507（7）,γ = 97.157（7）°,V =1854.2（3） A°3,Z = 4,crystal size（mm） = 0.25 × 0.1 × 0.1 and R（int） = *** asymmetric unit contains two independent *** crystal structure of the title compound is stabilized by intramolecular interactions of types C-H…N and C-H…***,X-ray analysis reveals obvious C-H…π,π-π stacking interactions between two adjacent aromatic ring planes.

关键词： click chemistry trisubstituted triazole alkyne crystal structure C–H…π interactions

Three new anthraquinone derivatives isolated from Symplocos racemosa and their antibiofilm activity

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Chinese Journal of Natural Medicines 2017年第12期15卷 944-949页

作者： Umar Farooq Sara Khan Sadia Naz Ajmal Khan Afsar Khan Ayaz ahmed Abdur Rauf Syed Majid Bukhari Shujaat Ali Khan Arfa Kamil Nadia riaz Abdur Rahman Khan Department of Chemistry COMSATS Institute of Information Technology Abbottabad-22060 Pakistan Dr. Panjwani Center for Molecular Medicine and Drug Research International Center for Chemical and Biological Sciences University of Karachi- 752 70 Pakistan Department of Geology University of Swabi Anbar-23430 KPK Pakistan Institute of Chemical Sciences University of Peshawar Peshawar 25120 Pakistan Department of Pharmaceutical Chemistry Faculty of Pharmacy Federal Urdu University of Arts Science and Technology Karachi Karachi 75300 Pakistan Department of Environmental Sciences COMSATS Institute of lnformation Technology Abbottabad-22060 Pakistan

Three new alkyl substituted anthraquinone derivatives, trivially named as symploquinones A-C(Compounds 1-3) were isolated from Symplocos racemosa. The structures of these compounds were determined on the basis of extensive spectroscopic analyses(UV, IR, Mass, ~1 H-and ^(13)C-NMR, and two-dimensional(2D) NMR techniques). The resulting data were also compared with the reported literature. These compounds were then subjected to antibacterial or antibiofilm testing. Compounds 1 and 3 exhibited good antibacterial activity in the concentration range of 160-83 μg·m L^(-1) against Streptococcus mutans, methicillin resistant Staphylococcus aureus and Proteus mirabilis. Both compounds were further screened for anti-biofilm activity, which revealed promising activities at sub-MIC concentrations. None of the compounds were found to be active against Klebsiella pneumoniae.

关键词： Symplocos racemosa Substituted anthraquinone Antibiofilm activity