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Exploring the relationship between ambient sulfur dioxide and semen quality parameters:A systematic review and meta-analysis

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Asian pacific Journal of Reproduction 2024年第1期13卷 12-21页

作者： Seyed Sobhan Bahreiny Mojtaba Aghaei Mohammad reza Dabbagh Hamid Ghorbani Moslem Javidan reza mohammadpour fard Student Research Committee Ahvaz Jundishapur University of Medical SciencesAhvazIran Medical Basic Sciences Research Institute Physiology Research CenterDepartment of PhysiologySchool of MedicineAhvaz Jundishapur University of Medical SciencesAhvazIran Department of Biology Faculty of ScienceShahid Chamran University of AhvazAhvazIran Department of Immunology Faculty of MedicineAhvaz Jundishapur University of Medical SciencesAhvazIran

Objective:To investigate the relationship between ambient sulfur dioxide(SO2)exposure and semen quality ***:A systematic literature search was conducted to identify relevant studies investigating the association between SO2 exposure and semen quality *** search encompassed the timeframe from January 2000 to May 2023 and included electronic databases such as Web of Science,Google Scholar,PubMed,Cochrane,and *** effect estimates with 95%confidence intervals(CI)were calculated using percent changes(PC).The meta-analysis included seven studies with 6711 participants and 15087 semen ***:The results revealed a significant negative association between ambient SO2 exposure and certain semen quality *** particular,SO2 exposure was associated with a significant decrease in progressive motility(PC=0.032;95%CI:-0.063 to-0.001;P=0.044)and sperm concentration(PC=-0.020;95%CI:-0.036 to-0.005;P=0.012).However,no statistically significant associations were observed for total sperm count(PC=-0.038;95%CI:-0.079 to 0.003;P=0.070),seminal fluid volume(PC=-0.009;95%CI:-0.048 to-0.030;P=0.662)and sperm motility(PC=-0.17;95%CI:-0.363 to 0.022;P=0.830).In addition,the results of the subgroup analysis revealed specific variables that were associated with the decrease in relevant sperm ***:This systematic review and meta-analysis provides compelling evidence supporting a consistent negative association between exposure to ambient SO2 and semen quality parameters.

关键词： Semen quality Sulfur dioxide Ambient air pollution Meta-analysis

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Targeting miRNA by CRISPR/Cas in cancer:advantages and challenges

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Military Medical Research 2024年第3期11卷 345-373页

作者： Bashdar Mahmud Hussen Mohammed Fatih Rasul Snur Rasool Abdullah Hazha Jamal Hidayat Goran Sedeeq Hama Faraj Fattma Abodi Ali Abbas Salihi Aria Baniahmad Soudeh Ghafouri-fard Milladur Rahman Mark C.Glassy Wojciech Branicki Mohammad Taheri Department of Biomedical Sciences Cihan University-ErbilErbilKurdistan Region 44001Iraq Department of Clinical Analysis College of PharmacyHawler Medical UniversityErbilKurdistan Region 44001Iraq Department of Pharmaceutical Basic Science Faculty of PharmacyTishk International UniversityErbilKurdistan Region 44001Iraq Medical Laboratory Science Lebanese French UniversityErbilKurdistan Region 44001Iraq Department of Biology College of EducationSalahaddin University-ErbilErbilKurdistan Region 44001Iraq Department of Medical Laboratory Science Komar University of Science and TechnologySulaymaniyah 46001Iraq Department of Medical Microbiology College of Health SciencesHawler Medical UniversityErbilKurdistan Region 44001Iraq Department of Biology College of ScienceSalahaddin University-ErbilErbilKurdistan Region 44001Iraq Center of Research and Strategic Studies Lebanese French UniversityErbil 44001Iraq Institute of Human Genetics Jena University Hospital07747 JenaGermany Department of Medical Genetics School of MedicineShahid Beheshti University of Medical SciencesTehran 374-37515Iran Department of Clinical Sciences MalmöSection for SurgeryLund University22100 MalmöSweden Translational Neuro-Oncology Laboratory San Diego(UCSD)Moores Cancer CenterUniversity of CaliforniaSan DiegoCA 94720USA Faculty of Biology Institute of Zoology and Biomedical ResearchJagiellonian University31-007 KrakówPoland Urology and Nephrology Research Center Shahid Beheshti University of Medical SciencesTehran 374-37515Iran

Clustered regulatory interspaced short palindromic repeats(CRISPR)has changed biomedical research and provided entirely new models to analyze every aspect of biomedical sciences during the last *** the study of cancer,the CRISPR/CRISPR-associated protein(Cas)system opens new avenues into issues that were once unknown in our knowledge of the non-coding genome,tumor heterogeneity,and precision ***/Cas-based geneediting technology now allows for the precise and permanent targeting of mutations and provides an opportunity to target small non-coding RNAs such as microRNAs(miRNAs).However,the development of effective and safe cancer gene editing therapy is highly dependent on proper design to be innocuous to normal cells and prevent introducing other *** study aims to highlight the cutting-edge approaches in cancer-gene editing therapy based on the CRISPR/Cas technology to target miRNAs in cancer ***,we highlight the potential challenges in CRISPR/Cas-mediated miRNA gene editing and offer advanced strategies to overcome them.

关键词： CRISPR CRISPR/Cas9 CRISPR/Cas12 Gene editing miRNAs Cancer therapy

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Performance of passive and reactive profiled median barriers in traffic noise reduction

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2011年第1期12卷 78-86页

作者： Mohammad reza MONAZZAM Samaneh Momen Bellah fard Occupational Hygiene Department School of Public HealthTehran University of Medical Sciences Department of Environmental Science Graduate School of the Environment and EnergyScience and Research BranchIslamic Azad University

Median noise barriers, like parallel noise barriers, can be employed to reduce the impact of traffic on roadside communities via the direct propagation path. The performance of different shapes of median barriers was compared using reactive and passive surfaces and a 2D boundary element method (BEM). In the case of reactive surfaces, quadratic residue diffusers (QRDs) and primitive root diffusers (PRDs) were used on the top and stem surfaces of median barriers. To introduce passive barriers, two different absorbent materials including fibrous material and a grass surface with flow resistivity of 20 000 and 2500 kg/(s·m2), respectively, were similarly applied. The effect of thin absorptive barriers was similar at lower frequencies and better at mid and high frequencies to that of their equivalent rigid barriers. More improvement was achieved by covering the top surface of thick barriers with grass rather than with fibrous material. The performance of QRD and PRD barriers where the diffuser was located on the top surface was more frequency dependent than that of barriers coated with fibrous material. A comparison of the average A-weighted insertion loss in the thick barriers showed that the greatest improvement (2.59 dB (A)) was achieved using a barrier of 30-cm thickness covered with grass.

关键词： Absorption Quadratic residue diffuser (QRD) Primitive root diffuser (PRD) Noise barrier

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Stochastic framework for reliability enhancement using optimal feeder reconfiguration

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Journal of Systems Engineering and Electronics 2014年第5期25卷 901-910页

作者： Abdollah Kavousi-fard Taher Niknam Mohammad-reza Akbari-Zadeh Bahram Dehghan Nourabad Mamasani Branch Islamic Azad University Electronic and Electrical Department Shiraz University of Technology

Optimal distribution feeder reconfiguration （DFR） is a valuable and costless approach to increase the load balance, reduce the amount of power losses, and improve the voltage of the buses. In this way, this paper aims to investigate the optimal DFR strategy as a proper tool to improve the reliability of the radial distribution networks. The idea of failure rate reduction is employed to see the effect of feeder current reduction on the reliability of the system more accurately. The objects to be investigated are system average interruption frequency index （SAIFI）, system average interruption duration index （SAIDI）, average energy not supplied （AENS） and total active power losses. The problem is then formulated in a stochastic framework based on the point estimate method （PEM） to handle the uncertainty effects. The feasibility and satisfying performance of the proposed method is examined on a standard IEEE test system.

关键词： reliability enhancement uncertainty distribution systems optimal reconfiguration.

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Characteristics and clinical presentations of pediatric 0retinoblastoma in North-western Iran

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International Journal of Ophthalmology(English edition) 2012年第4期5卷 510-512页

作者： reza Nabie Nazli Taheri Ali Mahdavi fard Rohollah Fadaei Fouladi Department of Ophthalmology Nikookari Eye Hospital Tabriz University of Medical SciencesTabriz Iran Department of Ophthalmology Alavi Eye Hospital Tabriz University of Medical SciencesTabriz Iran Imam reza Hospital Tabriz University of Medical SciencesTabriz Iran

·AIM:To report the characteristics and clinical presentations of retinoblastoma in a series of pediatric patients from Iran. ·METHODS:In this retrospective study, profiles of pediatric patients with retinoblastoma archived in a referral eye hospital in north-west of Iran during 7 years (n =40 patients with 57 eyes) were reviewed. Demographics, as well as the laterality, clinical manifestations and the types of treatment were the major endpoints. The Student’s t test, Mann-Whitney U -test, Chi-square or Fishers’ Exact test was used for analysis where appropriate. ·RESULTS:There were 23 cases (57.7%) with unilateral and 17 cases (42.5%) with bilateral involvement. The male to female ratio was 1 to 1.4 with a mean admitting age of 24.0±11.3 (range:5-62) months. The mean diagnosis delay was (7.4±9.6) months (range:10 days to 13 months). The most common presenting sign was leukocoria (97.5%) followed by proptosis (7.5%), strabismus (7.5%), hyphema (5%), orbital cellulitis (5%) and glaucoma (2.5%). Enucleation was performed in 95.7% of the cases with unilateral involvement and at least one eye of the patients with bilateral disease. A second enucleation was performed in other 3 patients (17.6%) of the latter group. ·CONCLUSION:This is the first study evaluating a series of Iranian children with retinoblastoma.

关键词： retinoblastoma epidemiology clinical presentation

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Seismic geomorphology and stratigraphic trap analyses of the Lower Cretaceous siliciclastic reservoir in the Kopeh Dagh-Amu Darya Basin

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Petroleum Science 2019年第4期16卷 776-793页

作者： Gholamreza Hosseinyar reza Moussavi-Harami Iraj Abdollahie fard Asadollah Mahboubi Rooholah Noemani Rad Department of Geology Faculty of ScienceFerdowsi University of MashhadMashhad 91775-1436Iran Geophysics Department NIOC Exploration DirectorateTehran 19395-6669Iran

Lower Cretaceous Shurijeh–Shatlyk Formations host some of the main reservoirs in the Kopeh Dagh-Amu Darya *** in this area so far has focused on the development of structural traps, but recognition of stratigraphic traps in this area is of increasing importance. Integration of 3D seismic data with borehole data from thirteen wells and five outcrop sections was used to identify potential reservoir intervals and survey the hydrocarbon trap types in the East Kopeh Dagh Foldbelt(NE Iran). Analyses of horizontal slices indicated that the lower Shurijeh was deposited in a braided fluvial ***, three types of channel were identified in the lower Shurijeh Formation: type 1, which is low-sinuosity channels interpreted to be filled with non-reservoir fine-grained facies;type 2, which is a moderately sinuous sand-filled channel with good prospectively;and type 3, which is narrow, high sinuosity channel filled with fine-grained sediments. Results indicate that upper Shurijeh–Shatlyk Formations were deposited in fluvial to delta and shallow marine environments. The identified delta forms the second reservoir zone in the Khangiran Field. Study of the stratigraphic aspects of the Shurijeh succession indicates that both lower and upper Shurijeh reservoirs are stratigraphic reservoir traps that improved during folding.

关键词： 3D seismic Fluvial Stratigraphic trap Cretaceous Kopeh Dagh Amu Darya

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Assessment of land suitability and agricultural production sustainability using a combined approach (Fuzzy-AHP-GIS):A case study of Mazandaran province,Iran

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Information Processing in Agriculture 2020年第3期7卷 384-402页

作者： Sherwin Amini Abbas Rohani Mohammad Hossein Aghkhani Mohammad Hossein Abbaspour-fard Mohammad reza Asgharipour Department of Biosystems Engineering Faculty of AgricultureFerdowsi University of MashhadIran Unit of Agroecology Department of AgronomyFaculty of AgricultureUniversity of ZabolZabolIran

This research was conducted to evaluate the sustainability of rice production using fuzzy logic in Mazandaran province,*** untapped use of modern agricultural technology,such as agricultural machinery,has become a global dilemma,which has forced governments and environmentalists to take a serious stand against the dangers of massive non-standard agricultural practices in the *** types of mechanization,socioeconomic,and economic modeling were used to determine the sustainability and their values were collected through interview method using a 320-item questionnaire from 2016 to *** evaluation was carried out using soil and climate characteristics,so that about 27.4%of the area was in the perfectly suitable range(S1),35.2%in the appropriate range(S2),19.5%in the critical range(S3),and 17.9%in the inappropriate range(N)for rice *** were selected from two regions(R1 and R2)by the GIS on two lower levels and more than one hectare(A1,A2)according to agricultural methods(mechanical and traditional).The results showed that the highest and lowest means of the product were 4314.44 and 3501.95 kg ha1,*** sustainability of production was within the range of“sustainability”and“almost sustainable”in terms of mechanistic and economic factors in the fuzzy range of“moderate sustainability”and also with respect to social factors that are in a better position than mechanistic and economic *** of final sustainability model showed that the average of the lasting sustainability index was in the range of“almost unsustainable”and“moderate sustainability”.

关键词： Sustainable agriculture Fuzzy logics Environmental management Rice GIS AHP

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Accumulation of heavy metal in Platanus orientalis, Robinia pseudoacacia and Fraxinus rotundifolia

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Journal of Forestry Research 2013年第2期24卷 391-395页

作者： Sajjad Hosseinzadeh Monfared Mohammad Matinizadeh Anoushirvan Shirvany Ghavamedin Zahedi Amiri reza Mousavi fard Fariba Rostami Department of Forestry and Forest Economics Faculty of Natural Resources University of Tehran Research Institute of Forests and Rangelands of Iran Expert of parks organization of Karaj municipality

Plants are capable of reducing environmental pollutions through uptaking contaminants in their tissues. In the study site, twenty one-year-old leaves and shoots as well as twenty soil samples were sampled and analyzed by Inductively Coupled Plasma （ICP）. We investigated the uptaking ability of lead （Pb） and cadmium （Cd） by the leaves and shoots of Platanus orientalis, Robinia pseudoacacia and Fraxinus rotundifolia in Karaj city, the western Tehran, Iran. We also evaluated the total metal accumulation capacity by using metal accumulation index （MAI）. Results indicated that there was no significant difference in uptaking contents of Cd and Pb in the leaves among the trees. However accumulation of Cd in shoots of F. rotundifolia and R. pseudoacacia was significantly higher than that of P. orientalis. The accumulation of Pb in shoots of R. pseudoacacia was significantly higher than the other species. The amount of Pb in the soil of the study area was significantly higher than Cd. Concentrations of Cd and Pb in leaves of the three species are in the ranges of 2.4 2.7 mg Kg-1 and 7.1 14.4 mg Kg-1 , respectively. R. pseudoacacia had the highest MAI value for leaves （2.21） and F. rotundifolia had the highest MAI value for shoots （2.4）.

关键词： Platanus orientalis Robinia pseudoacacia Fraxinus rotundifolia heavy metals phytoremediation

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Use of specific acupuncture techniques in lingering nummular eczema:A case report

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Journal of Traditional Chinese Medical Sciences 2021年第2期8卷 166-170页

作者： Junxiang Wang Liangxiao Ma Mohammad reza Afshari fard Ali Mohammadi School of Acupuncture-Moxibustion and Tuina Beijing University of Chinese MedicineBeijing102488China Dey Clinic ShahriyarTehran***Iran Dr Ali Mohammadi Clinic of Acupuncture and Moxibustion RastakhizGohardashtAlborz***Iran

Background:Nummular eczema(NE)is an inflammatory skin disease characterized by pruritic coinshaped lesions and a long-lasting and easy-relapsing course,which severely decreases patients’quality of *** case was designed to observe the effects of specific acupuncture techniques on pruritic NE *** presentation:A 22-year-old female was first diagnosed with pruritic NE three years *** allergies were found in the patch test;while emotional stress would trigger and aggravate the *** application of 0.1%tacrolimus failed to reverse this condition over a long period of ***&outcomes:An individualized acupuncture treatment protocol was *** needling and encircling needling were applied at local eczematous lesions,with routine needling at meridian points,once per week,for 12 treatment *** outcome measures,including the Eczema Area and Severity Index,Visual Analogue Scale score for pruritus,Self-Rating Anxiety Score,and Dermatology Quality Life Index,substantially improved over 6 months from pre-treatment to 3 months ***:Acupuncture might be a promising non-pharmacological treatment method for patients with NE,especially for those with emotional stress.A randomized controlled trial with an adequate sample size and rigorous study design is required to verify the results of the study.

关键词： Nummular eczema Pruritus Anxiety Acupuncture techniques Half needling(Banci) Encircling needling(Weici)

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Undrained monotonic and cyclic behavior of sand-ground rubber mixtures

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Earthquake Engineering and Engineering Vibration 2018年第3期17卷 541-553页

作者： Shariatmadari N Karimpour-fard M Shargh A Department of Civil Engineering Iran University of Science and Technology Geotechnical Engineering Department of Civil EngineeringIran University of Science and Technology

In this study the stress–strain characteristics of sand-ground rubber mixtures are investigated in the sandlike zone,at different confining pressures,using hollow cylinder specimens subjected to torsional monotonic and cyclic *** monotonic loading a mixture of sand-ground rubber with 10% and 25% rubber content show more contraction behaviour than that observed in a pure sand *** transformation point in these mixtures are located on a larger shear *** expected,the shear strength of specimens decreases with increase of ground rubber ***,with increasing of effective confining pressure,the loss in shear strength of the mixture is *** addition,a mixture with 25% ground rubber shows a smaller loss in shear strength compared to a mixture with 10% ground rubber *** cyclic loading mixtures with 10% and 25% ground rubber have similar liquefaction resistance,especially at confining pressures of 110 k Pa and 260 k ***,by using of the mixture with 25% ground rubber,a larger volume of scrap tires could be *** addition of ground rubber to sand would affect the shear strain variation and excess pore water pressure trends,and this effect was further intensified with increasing ground rubber percentage.

关键词： Ground rubber tire crumbs liquefaction resistance hollow cylinder torsional apparatus monotonic and cyclic behaviour

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