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Self-Efficacy of the Learners:On the Road to English Language Learning

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Sociology Study 2021年第1期11卷 37-43页

作者： Roxanne reyes-Lorilla Bataan Peninsula State University BataanPhilippines

Poor student achievement is often attributed to a lack of motivation and *** with learning disabilities are very often unmotivated because school is one failure after another to *** are having a hard time assessing what could be the aid for language *** study used the descriptive-survey research *** is arranged to gather information about the present existing *** participants of this study consisted of 40 grade nine students from Mariveles National High School-Sisiman II *** questionnaire was divided into five parts—(A)Self Efficacy,(B)Intrinsic Motivation,(C)English Learning Value,(D)Performance Goal,and(E)Achievement *** on this study’s findings,some relevant and useful motivational learning implications are recommended for enhancement and improvement of the students’*** language improvement programs and activities are also discussed in accordance with the students’language difficulties as communicated in the open-ended questions to increase their motivation in English language learning.

关键词： motivation English language language learning academic achievement

For a Micro-Politics Analysis of Engineering Education

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Journal of Philosophy Study 2014年第8期4卷 574-589页

作者： Jose Aravena-reyes Federal University of Juiz de Fora

The idea that studies about education for engineers should be complemented with micro-politics analysis which is presented in this article. For such, we present a framework to conceptualizing micropolitics and some elements that show how the micro- and macro-politics are overlapped in any political fact. From this premise, the micro-politics is used to lift some elements of analysis of a particular case of engineering educational process in Brazil, where several dominant behaviors are characterized as violent or repressive behaviors that do not favor the development of technical inventivity, one of fundamental characteristics of the profession. What is argued here is that these behaviors are part of the range of a dominant subjectivity that has as its goal the maintenance of professional subjectivity not to develop in students a critical subjectivity, which must be produced under teaching techniques and pedagogical approaches. To consolidate the micro-politics analysis perspective are cited several statements used in Brazilian engineering education process, which diverts attention from the real reasons for failures in the engineers＂ education. Finally, a report of physics violence inside a Brazilian public institution is cited to illustrate how the coercive institutional power operates in the production of students＇ subjectivity.

关键词： micro-politics engineering education subjectivity production

A Transactive Energy Model for Smart Metering Systems Using Blockchain

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CSEE Journal of Power and Energy Systems 2021年第5期7卷 943-953页

作者： Juan C.Olivares-Rojas Enrique reyes-Archundia Jose A.Gutierrez-Gnecchi Ismael Molina-Moreno Jaime Cerda-Jacobo Arturo Mendez-Patino National Technological Institute of Mexico/Technological Institute of Morelia-Division of Graduate Studies and Research MoreliaMichoacan 58120Mexico. School of Electrical Engineering Michoacan University of San Nicolas de HidalgoMorelia 58030.Mexico

The lowering cost of electricity generation technologies by renewable means has caused the role of end-users to change from being a simple consumer to a producer of their *** new role has been called a prosumer and has contributed to modifying electricity markets,by allowing prosumers to merchandize the energy surplus to electricity companies and other *** fundamental key to any economic transaction is trust between the ***,new technologies,such as blockchain,are transforming transaction security,and allowing decentralization of the smart power *** study presents the development of a transactional model of electrical energy using the infrastructure of smart metering and blockchain systems to allow the commercialization of electrical energy by *** results show that for the Mexican electricity market,they can he good alternatives hy reducing subsidies and being more profitable than current rates.

关键词： Data visualization fault diagnosis IoT network photovoltaic system wireless remote monitoring

Management of chronic hepatitis B during pregnancy

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Gastroenterology Report 2018年第4期6卷 257-262,I0001页

作者： Aysha Aslam Karen Joanie Campoverde reyes Vijayram Reddy Malladi Rizwan Ishtiaq Daryl T.Y.Lau Liver Center Division of Gastroenterology and HepatologyDepartment of MedicineBeth Israel Deaconess Medical CenterBostonMassachusettsUSA Neuroendocrine Unit Department of MedicineMassachusetts General HospitalBostonMassachusettsUSA

Chronic hepatitis B is globally prevalent and is a major cause of cirrhosis and hepatocellular *** immunoprophylaxis against hepatitis B in pregnancy,perinatal transmission still occurs in at least 10%of the children born to a mother with high level of *** regarding hepatitis B therapy during pregnancy must take into account the benefits and safety for both the mother and the unborn *** this review,we summarize the current treatment options for chronic hepatitis B with a focus on management during pregnancy and the evidence-based strategies to prevent vertical transmission of hepatitis B virus(HBV).

关键词： Chronic hepatitis B pregnancy nucleoside analogue hepatitis B therapy

Hepatoprotective properties of oleanolic and ursolic acids in anti-tubercular drug-induced liver damage

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Asian Pacific Journal of Tropical Medicine 2016年第7期9卷 625-632页

作者： Gabriel A.Gutiérrez-Rebolledo Georgina A.Siordia-reyes Mariana Meckes-Fischer Adelina Jiménez-Arellanes Unidad de Investigación Médica en Farmacología (UIMF) UMAE Hospital de EspecialidadesCentro Médico Nacional-Siglo XXI (CMN-SXXI)Instituto Mexicano del Seguro Social (IMSS) Servicio de Patología UMAE Hospital de PediatríaCMN-SXXIIMSS Centro de Diagnóstico en Metabolismo Energético y Medicina Mitocondrial A.C.

Objective:To estimate to what extent the mixture of ursolic acid and oleanolic acid,in addition to the antitubercular standard regime,affects the hepatotoxicity ***:Liver injury was induced in male BALB/c mice by administering,per os and daily for 11 weeks,a combination of anti-Tubercular(anti-TB) agents Rifampicin(10 mg/kg),Isoniazid(10 mg/kg),and Pyrazinamide(30 mg/kg).The ursolic acid and oleanolic acid mixture at doses of 100 or 200 μg/mouse/day was subcutaneously injected throughout the entire study period(11 weeks).Biochemical and hematological analysis was supplemented by liver histological ***:Animals treated with the mixture of triterpenic acids exhibited significantly decreased aspartate transaminase and alanine aminotransferase levels and amelioration of the histopathological alterations produced by the anti-TB ***:The triterpene mixture is able to prevent the steatosis induced by the anti-TB drugs.

关键词： Ursolic acid Oleanolic acid Hepatoprotector effect Antitubercular drugs Triterpenes

Effect of Helicobacter pylori on gastric epithelial cells

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World Journal of Gastroenterology 2014年第36期20卷 12767-12780页

作者： Shatha Alzahrani Taslima T Lina Jazmin Gonzalez Irina V Pinchuk Ellen J Beswick Victor E reyes Department of Microbiology and Immunology University of Texas Medical Branch Galveston TX 77555 United States MSIII School of Medicine University of Texas Medical Branch Galveston TX 77555 United States Department of Internal Medicine University of Texas Medical Branch Galveston TX 77555 United States Departments of Molecular Genetics and Microbiology University of New Mexico Health Sciences Center Albuquerque NM 87131 United States Departments of Pediatricsand and Microbiology and Immunology University of Texas Medical Branch Galves-ton TX 77555 United States

The gastrointestinal epithelium has cells with features that make them a powerful line of defense in innate mucosal immunity. Features that allow gastrointestinal epithelial cells to contribute in innate defense include cell barrier integrity, cell turnover, autophagy, and innate immune responses. Helicobacter pylori (H. pylori) is a spiral shape gram negative bacterium that selectively colonizes the gastric epithelium of more than half of the world’s population. The infection invariably becomes persistent due to highly specialized mechanisms that facilitate H. pylori’s avoidance of this initial line of host defense as well as adaptive immune mechanisms. The host response is thus unsuccessful in clearing the infection and as a result becomes established as a persistent infection promoting chronic inflammation. In some individuals the associated inflammation contributes to ulcerogenesis or neoplasia. H. pylori has an array of different strategies to interact intimately with epithelial cells and manipulate their cellular processes and functions. Among the multiple aspects that H. pylori affects in gastric epithelial cells are their distribution of epithelial junctions, DNA damage, apoptosis, proliferation, stimulation of cytokine production, and cell transformation. Some of these processes are initiated as a result of the activation of signaling mechanisms activated on binding of H. pylori to cell surface receptors or via soluble virulence factors that gain access to the epithelium. The multiple responses by the epithelium to the infection contribute to pathogenesis associated with H. pylori.

关键词： Helicobacter pylori Apoptosis Gastric epithelial cells Proinflammatory cytokines Chronic inflammation Gastric diseases Gastric cancer

Immune evasion strategies used by Helicobacter pylori

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World Journal of Gastroenterology 2014年第36期20卷 12753-12766页

作者： Taslima T Lina Shatha Alzahrani Jazmin Gonzalez Irina V Pinchuk Ellen J Beswick Victor E reyes Department of Microbiology and Immunology University of Texas Medical Branch Galveston TX 77555 United States MS-III School of Medicine University of Texas Medical Branch Galveston TX 77555 United States Department of Internal Medicine University of Texas Medical Branch Galveston TX 77555 United States Departments of Molecular Genetics and Microbiology University of New Mexico Health Sciences Center Albuquerque NM 87131 United States Departments of Pediatrics and Microbiology and Immunology University of Texas Medical Branch Galveston TX 77555 United Statest

Helicobacter pylori(H. pylori) is perhaps the most ubiquitous and successful human pathogen, since it colonizes the stomach of more than half of humankind. Infection with this bacterium is commonly acquired during childhood. Once infected, people carry the bacteria for decades or even for life, if not treated. Persistent infection with this pathogen causes gastritis, peptic ulcer disease and is also strongly associated with the development of gastric cancer. Despite induction of innate and adaptive immune responses in the infected individual, the host is unable to clear the bacteria. One widely accepted hallmark of H. pylori is that it successfully and stealthily evades host defense mechanisms. Though the gastric mucosa is well protected against infection, H. pylori is able to reside under the mucus, attach to gastric epithelial cells and cause persistent infection by evading immune responses mediated by host. In this review, we discuss how H. pylori avoids innate and acquired immune response elements, uses gastric epithelial cells as mediators to manipulate host T cell responses and uses virulence factors to avoid adaptive immune responses by T cells to establish a persistent infection. We also discuss in this review how the genetic diversity of this pathogen helps for its survival.

关键词： Helicobacter pylori Immune response Pattern recognition receptors Phagocytes T cells Antigen presenting cells Gastric epithelial cells Vacuolating cytotoxin T4SS

Hepatitis C virus clearance and less liver damage in patients with high cholesterol, low-density lipoprotein cholesterol and APOE ε4 allele

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World Journal of Gastroenterology 2019年第38期25卷 5826-5837页

作者： Karina Gonzalez-Aldaco Sonia Roman Rafael Torres-Valadez Claudia Ojeda-Granados Luis A Torres-reyes Arturo Panduro Department of Molecular Biology in Medicine Civil Hospital of Guadalajara "Fray Antonio Alcalde" and Health Sciences Center University of Guadalajara

BACKGROUND Cholesterol is related to improvements in the rate of sustained virological response and a robust immune response against the hepatitis C virus(HCV).APOE gene polymorphisms regulate cholesterol levels modifying the course of the HCV *** relationship between cholesterol,APOE alleles,and the outcome of HCV infection has not been evaluated in the admixed population of *** To investigate the role of APOE-ε2,-ε3,and-ε4 alleles and the metabolic profile in the outcome of HCV *** A total of 299 treatment-na?ve HCV patients were included in this retrospective *** were stratified in chronic hepatitis C(CHC)(n=206)and spontaneous clearance(SC)(n=93).A clinical record was *** tests were assessed by dry chemistry *** genotypes were determined using a Real-Time polymerase chain reaction *** Total cholesterol,low-density lipoprotein cholesterol(LDL-c),triglycerides,and hypercholesterolemia were higher in SC than CHC patients as well as the frequency of the APOEε4 allele(12.4%vs 7.3%).SC patients were overweight(54.8%).Theε4 allele was associated with SC(OR=0.55,95%CI:0.31-0.98,P=0.042)and mild fibrosis(F1-F2)in CHC patients(OR 0.091,95%CI 0.01-0.75,P=0.020).LDL-c≥101.5 mg/dL(OR=0.20,95%CI:0.10-0.41,P<0.001)and BMI≥26.6 kg/m2(OR=0.37,95%CI:0.18-0.76,P<0.001)were associated with SC status;while ALT≥50.5 IU/L was negatively associated(OR=5.67,95%CI:2.69-11.97,P<0.001).CONCLUSION In SC patients,the APOEε4 allele and LDL-c conferred a protective effect in the course of the HCV infection in the context of excess body weight.

关键词： Liver damage Body mass index Spontaneous hepatitis C virus clearance Low-density lipoprotein Cholesterol

Hypothalamic-pituitary-adrenal axis function during perinatal depression

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Neuroscience Bulletin 2015年第3期31卷 338-350页

作者： Phillipe Leff Gelman Mónica Flores-Ramos Margarita López-Martínez Carlos Cruz Fuentes Juan Pablo reyes Grajeda National Institute of Perinatology Mexico City National Council of Sciences and Technology (CONACy T) Mexico City National Institute of Psychiatry Mexico City National Institute of Genomic Medicine Mexico City

Abnormal function of the hypothalamic-pituitary-adrenal （HPA） axis is an important pathological finding in pregnant women exhibiting major depressive disorder. They show high levels of cortisol pro- inflammatory cytokines, hypothalamic-pituitary peptide hormones and catecholamines, along with low dehydroepiandrosterone levels in plasma. During pregnancy, the TH2 balance together with the immune system and placental factors play crucial roles in the development of the fetal allograft to full term. These factors, when altered, may generate a persistent dysfunction of the HPA axis that may lead to an overt transfer of cortisol and toxicity to the fetus at the expense of reduced activity of placental 1113-hydroxysteroid dehydrogenase type 2. Epigenetic modifications also may contribute to the dysregulation of the HPA axis. Affective disorders in pregnant women should be taken seriously, and therapies focused on preventing the deleterious effects of stressors should be implemented to promote the welfare of both mother and baby.

关键词： brain depression neuroendocrine pregnancy stress glucocorticoids