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Therapeutic Route of Patients with Cirrhosis in Bangui

Open Journal of Gastroenterology 2020年第4期10卷 88-96页

作者： Serges Magloire Camengo Police Peggy Gué rendo Georges Service Benoî t Elowa Gaé tan Adouaka Eveline Mofini Armelo Thibaut Yangba Kalebanga Nathalie Philomè ne Boua-Akelelo Bernard Bessanguem Joseph Rogevr Molowa Kobendo Department of Hepato-Gastroenterology and Internal Medicine of “Amitié Sino-Centrafraine” University Hospital Center Bangui Central African Republic Department Venerology Dermatology National University Hospital Center Bangui Central African Republic Department of Internal Medicine “Maman Elisabeth Domitien” University Hospital Center Bimbo Central African Republic

Introduction: Cirrhosis is the final stage in the development of any chronic liver disease. The objective of our study was to determine the therapeutic route of patients with cirrhosis. Patients and Methods: This was a one-year cross-sectional study of consenting patients of both sexes with cirrhosis who were hospitalized for the first time. The study took place from October 1, 2013 to September 30, 2014. The diagnosis of cirrhosis was based on clinical, biological and morphological arguments. Results: In total, 1028 patients were hospitalized, including 202 for cirrhosis (19.6%). One hundred and four patients (10.1%) met our inclusion criteria. These were 70 men (67.3%) and 34 women (32.7%). The sex ratio was 2.05. The average age was 43.74 ± 13.74 years. In 68 cases (65.4%), cirrhosis was considered a supernatural disease and in 36 cases (34.6%) was a natural disease. At the first signs, 88 patients (84.6%) had consulted (traditional healer in 34 cases, pastor in 25 cases, marabout in 16 cases and general practitioner in 13 cases). The pastor prayed to 25 patients (24%). The traditional healer made the patients ingest herbal preparations (n = 18), associated or not with scarification (n = 4) and/or enema (n = 28). The marabout recited Quranic verses written on a board, then washed and ingested in 16 cases (15.4%). The general practitioner prescribed treatment to the 13 patients (12.5%). The various treatments received had led to hepatic encephalopathy (21 cases), digestive hemorrhage (15 cases), abdominal pain (3 cases), jaundice (3 cases), increased abdominal bloating (21 cases). The patients had consulted the specialist within an average of 74 ± 15.3 days. The average time to hospital was 21 days ± 13. Conclusion: Cirrhosis is diagnosed at the complication stage due to inappropriate treatment by pastors, marabouts and the general practitioner. The population must be made aware of the early use of health care facilities.

关键词： Therapeutic Route Cirrhosis Bangui

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Prevalence of HBsAg and Antibodies to Hepatitis C Virus among Female Sex Workers in Bangui

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Open Journal of Gastroenterology 2020年第6期10卷 144-150页

作者： Serges Magloire Camengo Police Nathalie Philomène Boua-Akélélo Georges Service Eveline Mofini Benoît Elowa Armelo Thibaut Yangba Kalebanga Bernard Bessanguem Marcel Mbeko Simaléko Peggy Guérendo Henri Diemer Jospeh Roger Molowa Kobendo Department of Hepato-Gastroenterology and Internal Medicine of “Amitié Sino-Centrafraine” University Hospital Center Bangui Central African Republic Department of Internal Medicine “Maman Elisabeth Domitien” University Hospital Center Bimbo Central African Republic National Reference Center for Sexually Transmitted Infections and Antiretroviral Therapy Bangui Central African Republic Department of Public Health Faculty of Health Sciences University of Bangui Bangui Central African Republic Department Venerology Dermatology National University Hospital Center Bangui Central African Republic

Introduction: Hepatitis B virus (HBV) and Hepatitis C Virus (HCV) infection is a public health problem. Sex workers remain a vulnerable group. Objective: To determine the prevalence of HBsAg and hepatitis C virus (HCV) antibody transport among female sex workers (FSW) in Bangui. Patients and Methods: All FSW carriers of HBsAg and/or anti-HCV Antibodies were collected in a 6-month cross-sectional analytical study. The HBsAg research used the Monolisa HBsAg® (BioMérieux®) technique, sandwich ELISA. HCV serology consisted of the search for anti HCV antibodies by monolisa HCV (BioMérieux®), Elisa of the sandwich type. HIV serology used two Elisa tests (Genscreen® and Vironostika®). Data analysis was done using Epi Info 3.5.1 software. The Chi2 test was used for comparison with a signif

关键词： HBsAg Anti HCV Antibodies Female Sex Workers Bangui

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