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Approach to Paroxysmal Atrial Fibrillation Type Arrhythmia in a Cardiology Service:A Case Report

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Modern Research in Inflammation 2020年第2期9卷 9-17页

作者： Miriam Viviane Baron Luis Manuel Ley Dominguez Carolina Paz Mohamad Isa Gabriela Di Lorenzo Garcia Scherer Michele Paula dos Santos Vitoria Pereira Itaquy Talia Guimaraes dos Santos Julia Braga da Silveira Paulo Ricardo Martins Amanda Correa dos Santos Marcus Vinicius de mello Pinto Janine Koepp Daiana Klein Weber Carissimi Joice Nedel Ott Carolina Goncalves Pinheiro Nathalia Ken Pereira Iketani Gabriela Feltez Bartira Ercília Pinheiro da Costa Postgraduate Program in Medicine and Health Sciences of the Pontifical Catholic University of Rio Grande do Sul(PUC/RS) Porto AlegreBrazil Improvement of Higher Education Personnel Brazil(CAPES)Distrito FederalBrazil School of Medicine of the Pontifical Catholic University of Rio Grande do Sul(PUC/RS) Porto AlegreBrazil School of Health and Life Sciences of the Pontifical Catholic University of Rio Grande do Sul(PUC/RS) Porto AlegreBrazil Celulare Institute PetrópolisBrazil Undergraduate Nursing Course of the University of Santa Cruz do Sul(UNISC) Santa Cruz do SulBrazil Postgraduate Program in Health Sciences of the Faculty of Medicine of ABC(FMABC) Sao PauloBrazil Undergraduate Physiotherapy Course of the Vale do Salgado Faculty(FVS) CearáBrazil Physiotherapy of the Hospital Beneficiente Portuguesa of Belém ParáBrazil Rehabilitation Sciences of the Federal University of Health Sciences of Porto Alegre Porto AlegreBrazil Postgraduate Program in Medicine and Health Sciences School of Medicine of the Pontifical Catholic University of Rio Grande do Sul(PUC/RS)Porto AlegreBrazil

Atrial fibrillation is a cardiac arrhythmia of high prevalence in the population, especially in the elderly. Its main electrical characteristics are the interval between two successive irregular R waves, absence of P waves and presence of f waves between QRS complexes. The most common symptoms of atrial fibrillation are irregular palpitations associated with dyspnea, dizziness, feeling tired, fatigue and general malaise, but not all patients have any symptoms. The present report presents the history of an elderly patient who arrived at the hospital’s emergency department with irregular heart rhythm and palpitations. The patient’s symptoms, associated with the electrocardiogram results, indicated paroxysmal atrial fibrillation. Electrical cardioversion was performed, and after, cardiac ablation via the femoral vein at the hospital’s cardiology service. There were no complications during the procedure. As a routine imaging exam after ablation, control esophagogastroduodenoscopy was requested to verify that there was no formation of atrio-esophageal fistula developed by the invasive ablation procedure and electrocardiogram, which showed normal sinus rhythm. The patient remained in the cardiac intensive care unit for observation for 24 hours. After the electrical cardioversion and catheter ablation procedures, the patient improved his clinical picture of atrial fibrillation and was discharged after 24 hours of hospitalization. He received treatment to perform at home, to reduce acid reflux into the esophagus and to prevent thrombosis. He did not present pulmonary thromboembolism after hospital discharge. It is believed, therefore, that this form of treatment and management of paroxysmal atrial fibrillation is effective for the solution of the proposed problem and can also serve as a reference for other professionals within the cardiology service.

关键词： Atrial Fibrillation Electrical Cardioversion Catheter Ablation Hypertension Obstructive Sleep Apnea Syndrome

Activation of PAR1 increases cardiac action potential duration through stimulation of the late Na current.

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Activation of PAR1 increases cardiac action potential durati...

Electrochemical and Photoelectrochemical decoloration of Amaranth Dye Azo Using Composited Dimensional Stable Anodes

第十五届国际药理学大会

作者： S. Sablayrollesl R. Letienne C. Pinet A. Coulombe M. perez B.Le Grand Centre de Recherche Pierre Fabre Castres Centre de Recherche Pierre Fabre Castres INSERM U-621 CHU Pitié Salpétrière Paris France INSERM U-621 CHU Pitié Salpétrière Paris France Centre de Recherche Pierre Fabre Castres Centre de Recherche Pierre Fabre Castres

＜正＞ Thrombin constitue the main activator of the protease activated receptor PAR1, however, to date only few informations are available on the pathophysiological relevance of PAR1 in the heart. The main goal of the present study was to investigate the affect of PAR1 activation on the action potential duration of guinea-pig papillary. Firstly, an immunochemistry study using monoclonal mouse antibody to thrombin demonstrate the presence of PAR1 with a great density on the endocardium. Using the patch-clamp technique on freshly isolated cardiomyocytes, we demonstrate activation of PAR1 with thrombin 32UI/ml increase the amplitude of the late sodium current （2.2±0.5pA/pF）. In addition, the action potential duration were significantly increase APD50 in a concentration dependent manner both by thrombin 32UI/ml （max van 14.80% ） and by SFLLR 100μM （max van 13, 09% ）. In each case, these PAR1 activations were fully block by TTX 1μM confirming the involvement of the late sodium current in the action potential prolongation. Similarly, the PAR1 induced an increase of APD50 was concentration de-pendently block by two PAR1 antagonist compounds, SCH 203099 and ER 112787.

关键词： PAR1 APD Late Sodium Current.

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Journal of Environmental Protection 2013年第1期4卷 136-143页

作者： Moisés I. Salazar-Gastélum Edgar A. Reynoso-Soto Shui W. Lin Sergio perez-Sicairos Rosa M. Félix-Navarro Ingeniería en Nanotecnología Centro de Graduados e Investigación en Química del Instituto Tecnológico de Tijuana Tijuana México

In this paper we report the results of our experimental work conducted to decoloration of a well-known highly toxic Amaranth dye by electrochemical and photoelectrochemical methods. Throughout this investigation were used two different Dimensional Stable Anode (DSA) electrodes, namely, IrO2-Ru2O-SnO2-TiO2/Ti and Ru2O-SnO2-TiO2/Ti. The experimental results show that IrO2-Ru2O-SnO2-TiO2/Ti electrode has higher performance on amaranth decoloration than Ru2O-SnO2-TiO2/Ti electrode, but with the disadvantage of higher energy consumption. For higher degradation of Amaranth dye with both DSA electrodes, the process was carried out via photoelectrochemical method. Our experimental results clearly shown the decrease in absorbance of all UV-Vis peaks due to the mineralization of the azo dye;also, it was noteworthy photoelectrochemical process consumes less energy under the same experimental conditions than electrochemical process. The IrO2-Ru2O-SnO2-TiO2/Ti electrode reaches a higher degradation degree of Amaranth solutions than Ru2O-SnO2-TiO2/Ti electrode using a photoelectrochemical technique.

关键词： Photoelectrochemical decoloration DSA Azo Amaranth Dye

development of Active Films with Collagen Fiber and Polyvinyl Alcohol Mixture and Incorporation of Oregano and Rosemary Essential Oils in Their Matrix

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Advanced Stage Stuck Gland Adenocarcinoma:Case Report

Food and Nutrition Sciences（食品与营养科学） 2023年第7期

作者： Suslin Raatz Thiel Mari Silvia Rodrigues de Oliveira Vinícius Badia Stephanie Reis Ribeiro Roger Wagner Tatiana Emanuelli Rosa Cristina Prestes Renius mello

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Modern Research in Inflammation 2020年第1期9卷 1-7页

作者： Miriam Viviane Baron Michele Paula dos Santos Gabriela Di Lorenzo Garcia Scherer Luis Manuel Ley Dominguez Vitoria Pereira Itaquy Natalia Cardoso Nascimento Fernanda Nerys Tais Michele Werle Carolina Paz Mohamad Isa Carina Marangoni Mariana Martins Dantas Santos Marcus Vinicius de mello Pinto Janine Koepp Daiana Klein Weber Carissimi Joice Nedel Ott Carolina Goncalves Pinheiro Nathália Ken Pereira Iketani Bartira Ercília Pinheiro da Costa Postgraduate Program in Medicine and Health Sciences of the Pontifical Catholic University of Rio Grande do Sul(PUC/RS) Porto AlegreBrazil Improvement of Higher Education Personnel Brazil(CAPES)Distrito FederalBrazil School of Medicine of the Pontifical Catholic University of Rio Grande do Sul(PUC/RS) Porto AlegreBrazil School of Health and Life Sciences of the Pontifical Catholic University of Rio Grande do Sul(PUC/RS) Porto AlegreBrazil Celulare Institute PetrópolisRio de JaneiroBrazil Undergraduate Nursing Course of the University of Santa Cruz do Sul(UNISC) Santa Cruz do SulBrazil Postgraduate Program in Health Sciences of the Faculty of Medicine of ABC(FMABC) Sao PauloBrazil Undergraduate Physiotherapy Course of the Vale do Salgado Faculty(FVS) CearáBrazil Physiotherapy of the Hospital Beneficiente Portuguesa of Belém ParáBrazil

Parotid gland adenocarcinoma is commonly a tumor of low malignancy and low incidence worldwide. The reported case shows the rapid progression of this tumor in an elderly patient and infrequent effects, such as a presentation of facial edema not commonly described in the medical literature. Patient was admitted to hospital in November 2019 with secretion and partial hearing loss in the right ear and infiltrative and stone lesion with initial skin ulceration in the right cervical region. After 42 days, he returned and was admitted to the intensive care unit with significant swelling of the face, hardened and hyperemic neck, difficulty in speech and inability to open the eye. He presented changes in the mobility of the speech and hearing organs, reduced laryngeal mobility, vocal changes, speech with altered articulation and severe oropharyngeal dysphagia with risk of bronchoaspiration. The patient was diagnosed in September 2019 with a parotid tumor (salivary gland adenocarcinoma T4). The medical team requested computed tomography, computed tomography angiography of the chest and cervical vessels and computed tomography of the neck, in addition to evaluation by the head and neck surgery service and general surgery. After analyzing the results, the medical team suggested a hypothesis of tumor invasion that could result in obstruction of local lymphatic drainage, something unusual in the evolution of this type of tumor. In addition, it was not possible to adhere to radiotherapy treatment due to the extent of the lesion and there was also no confirmation of metastases. The reported case shows us that parotid gland adenocarcinoma, when diagnosed in an advanced stage, can limit the approach to treatment. It was chosen in agreement with the family to proceed with palliative care without invasive measures. Palliative care may be the best option for cases like this, bringing some comfort to the patient and his family.

关键词： Parotid Neoplasms Cancer of the Parotid Palliative Care Critical Care

Botulinum Toxin A, Effect on Tensile Strength of Skin Wounds;Animal Study

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Journal of Biosciences and Medicines 2020年第2期8卷 17-24页

作者： Carlos A. Gonzalez-Alvarado Juan Garzon-Muvdi Roxanna perez-Garmendia Victoria Ramirez Luz Graciela Cervantes Adriana Rodriguez-Gomez Rodrigo Davila-Diaz Cuahutemoc Marquez-Espriella Plastic and Reconstructive Surgery Division Hospital Central Sur de alta Especialidad de Petroleos Mexicanos Mexico City Mexico Experimental Surgery department Instituto Nacional de Ciencias Medicas y Nutrición Salvador Zubiran Mexico City Mexico Pharmacology department Instituto Nacional de Cardiologia Ignacio Chavez Mexico City Mexico Pathology department Hospital Angeles del Pedregal Mexico City Mexico

Wound healing and cicatrization is a process that involves several phases. The main goal of a surgeon and specially the plastic surgeon is to achieve the best cosmetic results and avoid complications. Several tools are available to achieve the best result. One of the tools recently studied is the use of Botulinum toxin. The use of Botulinum toxin has showed to be a useful aid by improving macroscopic cosmetic changes, as histopathologic ones. The increase of the tensile strength is also one of the positive changes that come with the use of botulinum toxin.

关键词： Botulinum Toxin Wound Tensile Strength

degradation and detoxification of Banana Postharvest Treatment Water Using Advanced Oxidation Techniques

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Green and Sustainable Chemistry 2011年第3期1卷 39-46页

作者： Dunia E.Santiago Elisenda Pulido Melian Cristina Fernandez Rodriguez Jose A.Ortega Mendez Sebastian O.perez-Baez Jose M.Dona-Rodriguez Grupo de Photocatalisis y Espectroscopia Aplicada al Medioambiente-FEAM(Unidad Asociada al Instituto de Ciencia de Materiales de Sevilla C.S.I.C.)CIDIA-Depto.de QuimicaEdificio del Parque Cientifico TecnologicoUniversidad De Las Palmas De Gran CanariaLas PalmasSpain

The elimination and detoxification of water contaminated with the principal commercial fungi-cides—thia- bendazole (Textar 60 T) and imazalil sulphate (Fruitgard IS 7.5)—used in the postharvest treatment of bananas was successfully achieved through the use of advanced oxidation processes (AOPs). The techniques tested were heterogeneous photocatalysis with TiO2 and TiO2-activated carbon (TiO2-CA) and Fenton and photo-Fenton processes. The evolution of fungicide concentration during degradation was studied together with mineralization and toxicity levels. When treated with any of the methods under study, the water meets the conditions stipulated by the legislation currently in force for its reuse in irrigation. However, this study proposes that the Fenton process is the best option for treatment of this type of water due to the efficiency of its reactions and its low economic cost.

关键词： Thiabendazole Imazalil Sulphate Photocatalysis Fenton Photo-Fenton Banana Postharvest

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Health 2020年第10期12卷 1360-1370页

作者： Lucas Lima de Carvalho Lucas Rodrigues Claro Amanda dos Santos Cabral Marcela Pereira da Silva mello Bruna Liane Passos Lucas Marcelly Valadares Souza Simone Fonseca Lucas Alexandre Oliveira Tellles Ravini Fernandez dos Santos Vieira dos Santos Marcia Augusta Pereira dos Santos Claudia Lima Campos Alzuguir Maria Cristina Dias da Silva Antonio Eduardo Vieira dos Santos Maria Antonieta Rubio Tyrrell Eduardo Alexander Júlio César Fonseca Lucas Anna Nery School of Nursing Federal University of Rio de Janeiro Rio de Janeiro Brazil Celso Lisboa University Center Rio de Janeiro Brazil State Secretariat of Education of Rio de Janeiro Rio de Janeiro Brazil department of Medicine in Primary Health Care Faculty of Medicine Federal University of Rio de Janeiro Rio de Janeiro Brazil department of Maternal and Child Nursing Faculty of Nursing State University of Rio de Janeiro Rio de Janeiro Brazil department of Maternal-Child Nursing Faculty of Nursing Fernandez Figueira Institute of the Oswaldo Cruz Foundation State University of Rio de Janeiro Rio de Janeiro Brazil

This documentary research aimed to describe the results of an epidemiological survey that sought to determine the prevalence of Infections Related to Health Care (IRHC) in newborns admitted to a Neonatal Intensive Care Unit (NICU) at the city of Rio de Janeiro. For methodology, the existing data in the original research database were used as the primary source. The method used was the case study in a quantitative approach. The data have been statistically arranged by odds ratio, which measured the possibility of IRHC development at the 102 newborns, by exposition at the risk factors. Results: IRHC prevalence with pneumonias, sepsis, navel’s infection and ocular infections predominance rises. Prematures are 4.10 more susceptible. Twelve hours after amniotic rupture there are 1.77 more chances of infections. Babies with more than 10 days of hospitalization are 4.70 more susceptible than those with 10 days. The registers examined were incipient at the IRHC’s characterization, beginning and duration, which make the IRHC’s diagnostic/notification difficult.

关键词： Neonatal Nursing Cross Infection Data Interpretation Statistical

A Structure and Antioxidant Activity Study of Paracetamol and Salicylic Acid

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Pharmacology & Pharmacy 2014年第13期5卷 1185-1191页

作者： Rosivaldo SBorges Taina G.Barros Glaecia A.N.Pereira Joao Batista Jr Raimundo F.G.P.Beleza Filho Andrex A.S.Veiga Moises Hamoy Vanessa J.mello Alberico B.Fda Silva Carlos A.L.Barros Nucleo de Estudos e Selecao de Moleculas Bioativas Instituto de Ciencias da SaudeUniversidade Federal do ParaBelemBrazil Laboratorio de Farmacologia e Toxicologia de Produtos Naturais Instituto de Ciencias da SaudeUniversidade Federal do ParaBelemBrazil Instituto de Quimica de Sao Carlos Universidade de Sao PauloSao CarlosBrazil

The paracetamol has more antioxidant properties than the salicylic acid on the several oxidative stress-forced models and one possible mechanism is due to electron or hydrogen transfer by the evaluated hydroxyl radicals. The antioxidant mechanism for the compounds studied here was performed by molecular modeling using quantum chemical calculations at the B3LYP level of theory. Our results show that the paracetamol has more antioxidant properties than the salicylic acid in experimental and theoretical studies. The theoretical mechanism show that the hydrogen transfer is more favorable than the electron transfer. From the study it was concluded that the electron abstraction for paracetamol is more favored than salicylic acid.

关键词： Paracetamol Salicylic Acid Phenol derivatives NSAIDs Antioxidant