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China Ocean Engineering 2018年第2期32卷 216-225页

作者： YU Guo-qing ren yi-ru ZHANG Tian-tian XIAO Wan-shen JIANG Hong-yong State Key Laboratory of Advanced Design and Manufacturing for Vehicle Body Hunan University College of Mechanical and Vehicle Engineering Hunan University Strategic Development Department China Three Gorges Corporations

A damage assessment methodology based on the Hashin failure theory for glass fiber reinforced polymer(GFRP)composite blade is proposed. The typical failure mechanisms including the fiber tension/compression and matrix tension/compression are considered to describe the damage behaviors. To give the flapwise and edgewise loading along the blade span, the Blade Element Momentum Theory(BEMT) is adopted. In conjunction with the hydrodynamic analysis, the structural analysis of the composite blade is cooperatively performed with the Hashin damage model. The damage characteristics of the composite blade, under normal and extreme operational conditions,are comparatively analyzed. Numerical results demonstrate that the matrix tension damage is the most significant failure mode which occurs in the mid-span of the blade. The blade internal configurations including the box-beam, Ibeam, left-C beam and right-C beam are compared and analyzed. The GFRP and carbon fiber reinforced polymer(CFRP) are considered and combined. Numerical results show that the I-beam is the best structural type. The structural performance of composite tidal turbine blades could be improved by combining the GFRP and CFRP structure considering the damage and cost-effectiveness synthetically.

关键词： composites tidal current turbine blade damage assessment tidal energy Hashin failure theory blade design

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基于拓扑优化的直升机旋翼桨叶剖面设计

工程力学 2014年第5期31卷 244-250页

作者：任毅如向锦武北京航空航天大学航空科学与工程学院北京100191

提出了一种基于拓扑优化的直升机旋翼桨叶剖面设计方法。采用了有限元方法计算直升机旋翼桨叶剖面刚度特性,截面考虑了剪切和翘曲变形,并消除了翘曲位移和刚体位移之间的耦合作用。基于SIMP拓扑优化算法,以旋翼桨叶平均柔度或者剖面刚... 详细信息

提出了一种基于拓扑优化的直升机旋翼桨叶剖面设计方法。采用了有限元方法计算直升机旋翼桨叶剖面刚度特性,截面考虑了剪切和翘曲变形,并消除了翘曲位移和刚体位移之间的耦合作用。基于SIMP拓扑优化算法,以旋翼桨叶平均柔度或者剖面刚度为设计目标,桨叶重量为约束函数,建立了旋翼桨叶拓扑优化模型。提出的敏度求解算法具有较高的计算精度,采用序列线性规划算法对旋翼桨叶剖面进行优化设计。结果表明在展长较小并且承受均布升力载荷情况下,Ⅱ型截面梁的柔度最小,而当展长增大时,工字梁截面具有最小的柔度。此外,旋翼桨叶外载荷等对优化结果也有较大的影响。提出的拓扑优化方法适合于概念设计阶段的直升机旋翼桨叶剖面设计。

关键词：直升机旋翼桨叶拓扑优化翘曲变形序列线性规划

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黑麦特异性PCR反应体系的建立

安徽农业科学 2011年第13期39卷 7582-7584,7946页

作者：任如意牡丹江师范学院生命科学与技术学院黑龙江牡丹江157012

[目的]建立黑麦特异性PCR反应优化体系。[方法]以普通小麦＂中国春＂、S165、黑麦、八倍体小黑麦、六倍体小黑麦为试验材料,研究了模板DNA、引物、dNTPs、Mg2＋浓度、TaqDNA聚合酶用量及退火温度对黑麦特异性PCR反应体系的影响。[结果]... 详细信息

[目的]建立黑麦特异性PCR反应优化体系。[方法]以普通小麦＂中国春＂、S165、黑麦、八倍体小黑麦、六倍体小黑麦为试验材料,研究了模板DNA、引物、dNTPs、Mg2＋浓度、TaqDNA聚合酶用量及退火温度对黑麦特异性PCR反应体系的影响。[结果]采用改良的CTAB DNA微量提取法可以得到高质量的基因组DNA,满足PCR反应模板的要求,黑麦特异PCR扩增反应体系为：在25μl反应体系中,10×缓冲液,1.5 mmol/LMgCl2,200μmol/LdNTP,40 ng引物,40~60 ng模板DNA,1 UTaq酶。[结论]建立了适宜的黑麦特异PCR扩增反应体系,为小麦背景下黑麦外源种质的检测奠定了基础。

关键词：黑麦 PCR反应体系优化

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医学论文英语写作的文体特点

实用儿科临床杂志 2009年第17期24卷 1383-1384页

作者：任如意新乡医学院外语系河南新乡453003

随着现代医疗科技的飞速发展,医疗卫生领域国际间的学术交流与合作日益加强,掌握必要的医学论文英语写作知识,对提高医疗专业人士的专业能力十分重要。医学英语具有其独特的文体特征,现拟从英语文体学角度出发,探讨医学论文英语写作的... 详细信息

随着现代医疗科技的飞速发展,医疗卫生领域国际间的学术交流与合作日益加强,掌握必要的医学论文英语写作知识,对提高医疗专业人士的专业能力十分重要。医学英语具有其独特的文体特征,现拟从英语文体学角度出发,探讨医学论文英语写作的文体特点,具体体现在常用的词汇、句法等方面。掌握这些必要的医学英语论文写作技巧和知识对儿科临床工作者具有理论指导和实践意义。

关键词：医学英语文体特点词汇句法

Inhibitory gamma-aminobutyric acidergic neurons in the anterior cingulate cortex participate in the comorbidity of pain and emotion

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Neural Regeneration Research 2025年第10期20卷 2838-2854页

作者： Lu Guan Mengting Qiu Na Li Zhengxiang Zhou ru Ye Liyan Zhong Yashuang Xu Junhui ren yi Liang Xiaomei Shao Jianqiao Fang Junfan Fang Junying Du Department of Neurobiology and Acupuncture Research Third School of Clinical MedicineZhejiang Chinese Medical UniversityHangzhouZhejiang ProvinceChina Key Laboratory for Research of Acupuncture Treatment and Transformation of Emotional Diseases Third School of Clinical MedicineZhejiang Chinese Medical UniversityHangzhouZhejiang ProvinceChina Fuchun Community Health Service Center of Fuyang District HangzhouZhejiang ProvinceChina

Pain is often comorbid with emotional disorders such as anxiety and *** of the anterior cingulate cortex has been implicated in pain and pain-related negative emotions that arise from impairments in inhibitory gamma-aminobutyric acid *** review primarily aims to outline the main circuitry(including the input and output connectivity)of the anterior cingulate cortex and classification and functions of different gamma-aminobutyric acidergic neurons;it also describes the neurotransmitters/neuromodulators affecting these neurons,their intercommunication with other neurons,and their importance in mental comorbidities associated with chronic pain *** understanding on their role in pain-related mental comorbidities may facilitate the development of more effective treatments for these ***,the mechanisms that regulate gamma-aminobutyric acidergic systems remain *** is also unclear as to whether the mechanisms are presynaptic or *** exploration of the complexities of this system may reveal new pathways for research and drug development.

关键词： anterior cingulate cortex anxiety chronic pain circuit communication comorbidity depression gamma-aminobutyric acidergic neurons parvalbumin neurons synaptic transmission

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基于遗传算法的潮流能水轮机翼型优化设计

湖南大学学报（自然科学版） 2015年第10期42卷 59-64页

作者：任毅如张田田曾令斌湖南大学机械与运载工程学院湖南长沙410082 中国长江三峡集团公司北京100036 广州船舶及海洋工程设计研究院广东广州510250

为了获得满足潮流能水轮机设计要求的专用翼型,基于遗传算法建立了水轮机翼型优化设计模型,该模型综合考虑了升力系数、阻力系数、升阻比和压力系数等因素,采用XFOIL评估翼型的水动力性能,对几种典型设计要求情况下的水轮机翼型进行了... 详细信息

为了获得满足潮流能水轮机设计要求的专用翼型,基于遗传算法建立了水轮机翼型优化设计模型,该模型综合考虑了升力系数、阻力系数、升阻比和压力系数等因素,采用XFOIL评估翼型的水动力性能,对几种典型设计要求情况下的水轮机翼型进行了优化设计.数值结果表明,该模型能够根据不同的设计要求获得相对应的水轮机翼型,不仅可以改善翼型的水动力系数,还能够避免翼型空化现象的产生.在最小化压力系数情况下,最大厚度位置更靠近翼型后缘,而最大化升力系数情况下则更靠近翼型前缘.为了达到指定的设计目标,需要考虑多个攻角下的升力系数或压力系数.

关键词：潮流能水轮机翼型水动性能空化

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孤舟〔组诗〕

中国诗歌 2017年第1期 59-64页

作者：任如意云南师范大学哲政学院

Exosomes:the next-generation therapeutic platform for ischemic stroke

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Neural Regeneration Research 2025年第5期20卷 1221-1235页

作者： Wenjing yin Hongyin Ma Yang Qu Jiaxin ren yingying Sun Zhen-Ni Guo yi Yang Stroke Center Department of NeurologyFirst Hospital of Jilin UniversityChangchunJilin ProvinceChina Neuroscience Research Center Department of NeurologyFirst Hospital of Jilin UniversityChangchunJilin ProvinceChina

Current therapeutic strategies for ischemic stroke fall short of the desired objective of neurological functional ***,there is an urgent need to develop new methods for the treatment of this *** are natural cell-derived vesicles that mediate signal transduction between cells under physiological and pathological *** have low immunogenicity,good stability,high delivery efficiency,and the ability to cross the blood–brain *** physiological properties of exosomes have the potential to lead to new breakthroughs in the treatment of ischemic *** rapid development of nanotechnology has advanced the application of engineered exosomes,which can effectively improve targeting ability,enhance therapeutic efficacy,and minimize the dosages *** in technology have also driven clinical translational research on *** this review,we describe the therapeutic effects of exosomes and their positive roles in current treatment strategies for ischemic stroke,including their antiinflammation,anti-apoptosis,autophagy-regulation,angiogenesis,neurogenesis,and glial scar formation reduction ***,it is worth noting that,despite their significant therapeutic potential,there remains a dearth of standardized characterization methods and efficient isolation techniques capable of producing highly purified *** optimization strategies should prioritize the exploration of suitable isolation techniques and the establishment of unified workflows to effectively harness exosomes for diagnostic or therapeutic applications in ischemic ***,our review aims to summarize our understanding of exosome-based treatment prospects in ischemic stroke and foster innovative ideas for the development of exosome-based therapies.

关键词： blood–brain barrier electroacupuncture engineering exercise exosomes ischemic stroke mesenchymal stem cells microglia neuroprotection stents

Establishment and Optimization of Rye-specific PCR Reaction System

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Agricultural Science & Technology 2011年第2期12卷 201-204页

作者：任如意牡丹江师范学院生命科学与技术学院黑龙江牡丹江157012

[Objective] The aim was to establish the optimal rye-specific PCR reaction system for rye.[Method] The ordinary wheat ＂Chinese Spring＂,S165,rye,octoploid triticale and hexaploid triticale were used as materials to carry out study on the effect of the amount of template DNA,primers,dNTPs,Mg2＋ concentrations,Taq DNA polymerase and annealing temperature on the rye-specific PCR reaction system of rye.[Result] The genomic DNA extracted by modified CTAB DNA extraction method showed high quality,which was satisfied for the PCR reaction *** rye-specific PCR reaction system was 25 μl,including 10 × buffer solution,1.5 mmol/L MgCl2,200 μmol/L dNTP,40 ng primers,40-60 ng DNA template and 1 U Taq DNA polymerase.[Conclusion] The optimal rye-specific PCR reaction system was established,which provided basis for the identification of exogenous germplasm of rye in wheat background.

关键词： Rye PCR reaction system Optimization

典型民机机身段水上冲击数值模拟方法及其耐撞性研究

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工程力学 2016年第5期33卷 241-248页

作者：任毅如向锦武郑建强罗漳平湖南大学机械与运载工程学院工程力学系湖南长沙410082 北京航空航天大学航空科学与工程学院北京100191 中国商用飞机有限公司北京民用飞机技术研究中心北京102211

为了改善民机在紧急迫降情况下的安全性能,对典型机身段水上冲击数值模拟方法及其冲击特性进行了研究。通过合理的简化建立了机身段有限元模型,对有限元方法(FEM)、任意拉格朗日/欧拉方法(ALE)和光滑粒子方法(SPH)水体模型进行了研究,... 详细信息

为了改善民机在紧急迫降情况下的安全性能,对典型机身段水上冲击数值模拟方法及其冲击特性进行了研究。通过合理的简化建立了机身段有限元模型,对有限元方法(FEM)、任意拉格朗日/欧拉方法(ALE)和光滑粒子方法(SPH)水体模型进行了研究,探讨了水体材料模型对机身段结构动态响应特性的影响。在7 m/s垂向冲击速度下,对比分析了水面和刚性地面情况下的机身段结构的耐撞性能。结果表明ALE方法具有最佳计算精度和计算效率。由于忽略了偏应力,采用空材料得到的机身结构响应与弹性流体和弹塑性水体材料有明显不同。在水上冲击过程中,由于水体耗散了大量冲击动能,因此机身加强框变形较小。机身底部蒙皮结构承受较大的均布载荷,因此蒙皮吸能结构吸收了较多的冲击动能,是最重要的吸能结构之一。相对于刚性地面,水面冲击情况下机身具有更小的加速度过载。在紧急迫降情况下,选择湖泊或者江河等水域作为迫降地点可以减小乘员承受加速度过载。

关键词：飞行器耐撞性有限元任意拉格朗日欧拉算法光滑粒子法