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Quantifying the sources of heterogeneity of fertility preferences in China

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China Population and Development Studies 2022年第2期6卷 127-140页

作者： Rui Lu Gert Stulp Anne H.gauthier Department of Sociology University of GroningenGroningenThe Netherlands Netherlands Interdisciplinary Demographic Institute(NIDI-KNAW) The HagueThe Netherlands

There are no unanimous estimates on fertility preferences in China;they vary considerably across *** this cross-study heterogeneity of reported preferred family size will contribute to the debates on the uncertainty of fertility in *** paper quantified how much heterogeneity in aggregate-level fertility preferences can be explained by taking into account the demographic characteristics of the sample,its geographical location,and the measurement of fertility *** retrieved 124 estimates of average preferred family size from 94 publications(from the year 2001 and onwards)in the China National Knowledge Infrastructure database(CNKI)and used mixed-effect meta-regression model to investigate *** found that the average preferred number of children in China since 2001 ranged from 0.91 to 2.88,with an average of 1.70(SD=0.26).Demographic differences accounted for 23%,human geographic regionalization for 21%,and the measurement of fertility preferences for 13%of the between-study *** characteristics(demographic and regional differences)and the measurement of fertility preferences together accounted for 46%of the variation in average preferred *** averaged preferred family size varies by differ-ent characteristics and *** study also points out whether particular groups have higher or lower *** helps researchers to put estimates from fertility preferences from single studies in ***,this study can help resolve why researchers have such different outlooks on the future fertility of China.

关键词： Fertility preferences China Heterogeneity Meta-analysis

Boundary Feedback Stabilization of a Hybrid System

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Boundary Feedback Stabilization of a Hybrid System

Overall Survival and Health Care Costs of Medicare Patients with Previously Treated Chronic Lymphocytic Leukemia

第十九届中国控制会议

作者： Boumediène CHENTOUF gauthier SALLET INRIA CONGE ＆ URA CNRS 399（MMAS） ISGMP Bat．AUniversité de Metz Ile de Saulcy 57045 MetzFrance INRIA CONGE ＆ URA CNRS 399（MMAS） ISGMP Bat．AUniversité de Metz Ile de Saulcy 57045 MetzFrance

＜正＞The paper deals with boundary feedback stabilization of an elastic beam which is clamped at one end and linked to a rigid body by the other end. The system is governed by the Euler-Bernoulli beam equation coupled with the Newton-Euler rigid body equation at the boundary. To stabilize the system we consider the boundary moment control and the boundary force control applied on the rigid body. We propose different stabilizing feedback laws and prove exponential stabilization in some cases. Analysis of the asymptotic eigenvalues of the closed-loop systems is carried out together with various numerical simulations. A set of physical parameters is made explicit such that the closed-loop system has non trivial trajectories with some classical feedback law and hence has no asymptotic stability.

关键词： Hybrid system exponential stabilization compact perturbation asymptotic analysis of the spectrum.

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Journal of Cancer Therapy 2018年第7期9卷 576-587页

作者： Carolina Reyes Genevieve gauthier Sherry Shi Annie Guerin Genentech Inc. South San Francisco CA USA Analysis Group Inc. Montreal Canada

Background: Bendamustine-based regimens are often used in the management of patients with chronic lymphocytic leukemia (CLL) but few studies have analyzed the comorbidity- and/or adverse event (CAE)-related healthcare costs in patients receiving these regimens in a real-world setting. Aims: To describe all-cause and CAE-related healthcare costs in relapse/refractory (R/R) elderly patients with CLL treated with bendamustine-based regimens in a real-world setting. Methods: Adult patients with R/R CLL who received bendamustine-based regimens on/after January 2010 were selected from the Medicare Limited Data Set (LDS) 5% Standard Analytic Files. Selected patients were classified into cohorts based on the two most prevalent bendamustine-based regimens observed (index treatment): 1) bendamustine + rituximab (BR cohort) and 2) bendamustine monotherapy (B-mono cohort). For each cohort, all-cause and CAE-related healthcare costs, while on treatment, were reported per-patient-per-month (PPPM). Overall survival (OS) rates following initiation of the index treatment were described using age- and gender-adjusted Kaplan-Meier curves. Results: A total of 275 patients were included in the BR cohort and 100 patients in the B-mono cohort. Most patients were male and the mean age was approximately 75 years old. During treatment, total all-cause healthcare costs were $14,520 PPPM for the BR cohort and $13,125 PPPM for the B-mono cohort—outpatient costs (mainly driven by CLL-drug costs) represented 86.1% of the total all-cause healthcare costs for the BR cohort and 69.8% for the B-mono cohort. CAE costs accounted for 58.3% of the total all-cause healthcare costs for the BR cohort and 66.9% for the B-mono cohort. Median OS was 35 months in the BR cohort and 21 months in the B-mono cohort. Conclusion: In this population of elderly patients with R/R CLL treated with bendamustine-based regimens, CAEs were common and translated into important medical costs. Median OS was also relatively shor

关键词： Chronic Lymphocytic Leukemia Relapse/Refractory Bendamustine Economic Burden Overall Survival Adverse Events

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基于琥珀酸衍生物为单体的聚酯的合成与表征

高分子材料科学与工程 2019年第11期35卷 17-22页

作者：程正载周佳丽刘盼盼谢聪王云胡海曾胜丁玲 Mario gauthier 武汉科技大学化学与化工学院精细有机化工与有机材料研究所湖北武汉430081 煤转化与新型炭材料湖北省重点实验室湖北武汉430081 湖北科技学院湖北省非动力核技术协同创新中心湖北咸宁437100

以1,4-环己二酮-2,5-二甲酸二甲酯(DMSS)为起始原料,采用两步法成功制备了2,5-二甲氧基对苯二甲酸二甲酯(DMDMT)。分别以DMDMT和不同碳链的脂肪二醇为单体,在三氧化二锑的催化作用下,采用熔融共聚酯交换法合成了4种由脂肪族二元醇-芳香... 详细信息

以1,4-环己二酮-2,5-二甲酸二甲酯(DMSS)为起始原料,采用两步法成功制备了2,5-二甲氧基对苯二甲酸二甲酯(DMDMT)。分别以DMDMT和不同碳链的脂肪二醇为单体,在三氧化二锑的催化作用下,采用熔融共聚酯交换法合成了4种由脂肪族二元醇-芳香族二元酸构成的聚酯。经过溶解、沉淀、离心等分离手段,得到目标聚酯a^d。通过红外光谱、核磁共振氢谱、凝胶渗透色谱、差示扫描量热分析和热重分析对其进行表征和分析。聚酯a^d的PDI在1.95~2.70之间,数均相对分子质量(Mn)在10000~15200之间。研究了聚合物中分子主链柔顺性对聚合物的热性能的影响,其中,聚酯a的熔点(Tm)较高,达到90℃,其初始分解温度(T5%)高达363℃;随着脂肪族碳链的碳数增加,所合成的聚酯a^d的熔点和初始分解温度(T5%)下降,这为新型脂肪族-芳香族聚酯的分子设计与合成提供了有益的参考。

关键词： 2,5-二甲氧基对苯二甲酸二甲酯脂肪族-芳香族聚酯热性能熔融共聚酯交换法

History of the Pollution in Tomsk Region (Siberia, Russia) According to the Study of High-Moor Peat Formations

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International Journal of Geosciences 2011年第4期2卷 493-501页

作者： Antonina Mezhibor Sergey Arbuzov Leonid Rikhvanov Francois gauthier-Lafaye 不详

A method that could be used to detect the change of the environment was used to determine the input of trace elements from the atmospheric fallouts into the biosphere near Tomsk city (West Siberia, Russia) during the last century. In this study we used high-moor peat formations because of the wide-spread occurrence of bogs in this region. Investigations of the raised peat bogs in areas with different degree of anthropogenic impact showed that the distribution of trace elements in the upper parts of peat deposits depends on the location of bogs towards industrial sources. The highest concentrations of Ca, Fe, Cr, Co, Sc, Hf and rare earth elements were found in the upper part of the bog located near the city Tomsk. Distribution of trace elements in the vertical profiles of raised peat deposits near cities Tomsk and Seversk reflects the industrial specialization of these cities and the dynamic of the atmosphere pollution. Studies of radioactive elements (137Cs, 238Pu, 239Pu) have indicated their inputs from global fallouts.

关键词： Atmosphere Pollution High-Moor Peat Trace Elements in Peat

Design of a Silicon Overlay Glass Waveguide Sensor

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Optics and Photonics Journal 2011年第4期1卷 151-154页

作者： Kristian E. Medri Robert C. gauthier 不详

A glass based slab waveguide, coated with a thin patterned high dielectric overlay, is configured into a refractive index sensor. The asymmetric nature of the waveguide configuration is exploited by keeping the mode in the slab waveguide while enhancing the field level in the overlay-superstrate. The sensor's response is examined using the FDTD simulation technique. A sensitivity of up to one part in 105 in the index of refraction discrimination is determined. The nature of the sensor ensures optical fibre compatibility, requires sub-μL sample volumes and provides a high resolution.

关键词： Refractive Index Sensor Slab Waveguide Patterned High Dielectric Overlay FDTD Integrated Optics

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烟气中重金属浓度的在线测量

化工学报 2006年第9期57卷 2185-2188页

作者：刘晶郑楚光陆继东 S.Abanades D.gauthier G.Flamant 华中科技大学煤燃烧国家重点实验室 CNRS-PROMES BP5 Odeillo66125 Font-RomeuFrance

An inductively coupled plasma atomic emission spectrometer （ICP-AES） was developed to continuously measure the heavy metals concentrations in flue gas in order to track the metal release *** system is devoted to the thermal treatment of metal-spiked mineral matrix, coal and municipal solid wastes in fluidized bed （850℃）.This method was used to study the kinetics of heavy metals *** optimum values of the gas flows from the 1200 W power generator were 0.1 L·min -1 for the sample gas and 0.2 L·min -1 for *** the thermal treatment of coal and municipal solid waste,Cd and Pb were released readily,while Zn was released at a lower level than Cd and *** formation of stable compounds such as ZnO·Al2O3 and CdO·Al2O3 from the reaction of heavy metals with fly ash particles could decrease heavy metals *** all cases, the experimental setup was successfully used to monitor the heavy metal release process during coal and solid waste thermal treatment.

关键词：在线测量重金属烟气流化床

Nitric Oxide in Plants： Production and Cross-talk with Ca^2＋ Signaling

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Molecular Plant 2008年第2期1卷 218-228页

作者： Angelique Besson-Bard Cecile Courtois Adrien gauthier Jennifer Dahan Grazyna Dobrowolska Sylvain Jeandroz Alain Pugin David Wendehenne Unite Mixte de Recherche INRA 1088/CNRS 5184/Universite de Bourgogne Plante-Microbe-Environnement 17 rue Sully BP 86510 21065 Dijon cedex France Institute of Biochemistry and Biophysics Polish Academy of Sciences 02-106 Warsaw Poland Unite Mixte de Recherche UHP INRA 1136 Interactions Arbres/Micro-Organismes Universite Henry Poincare Nancy I BP 239 54506 Vandoeuvre cedex France

Nitric oxide （NO） is a diatomic gas that performs crucial functions in a wide array of physiological processes in animals. The past several years have revealed much about its roles in plants. It is well established that NO is synthesized from nitrite by nitrate reductase （NR） and via chemical pathways. There is increasing evidence for the occurrence of an alternative pathway in which NO production is catalysed from L-arginine by a so far non-identified enzyme. Contradictory results have been reported regarding the respective involvement of these enzymes in specific physiological conditions. Although much remains to be proved, we assume that these inconsistencies can be accounted for by the limited specificity of the pharmacological agents used to suppress NO synthesis but also by the reduced content of L-arginine as well as the inactivity of nitrate-permeable anion channels in nitrate reductase- and/or nitrate/nitrite-deficient plants. Another unre- solved issue concerns the molecular mechanisms underlying NO effects in plants. Here, we provide evidence that the second messenger Ca^2＋, as well as protein kinases including MAPK and SnRK2, are very plausible mediators of the NO signals. These findings open new perspectives about NO-based signaling in plants.

关键词：蛋白激酶类钙精氨酸血气分析一氧化氮胰岛素植物铍动物

e-LITE:A Concurrent Engineering Method Dedicated to E-learning Training Development for the Enhancement of Research Project Results

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计算机教育 2012年第10期 12-17页

作者： AKIF J-Ch DANG T-N DUCQ Y gauthier P CNAM Pays of Loire Bordeaux University IMS Laboratory

Scientific research projects aim to produce new knowledge generally in domains of high *** of these projects have goals of improving the performance of *** this case,the issues of the capitalization and transfer of scientific knowledge and its rapid transformation into professional skills are directly ***,there is no method to derive e-learning teaching material from project ***,this paper presents the e-LITE Method and its application to the ISTA3 project to support the process of developing a e-learning *** application has allowed us to highlight the contributions of the method that promotes better knowledge sharing between partners of a research project and the development and transfer of research results to the professional ***,after the presentation of the method,an application to the ISTA3 project will be presented.

关键词： Concurrent engineering methodology Vocational training system e-learning Interoperability professional skill