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美国住房抵押贷款危机不断蔓延

工程经济 2007年第8期23卷 10-11页

作者： Gregory Zuckerman James R．Hagerty David gauthier-Villars

美国信贷市场危机愈演愈烈，从法国巴黎银行（BNP Paribas）到美国最大的住房抵押贷款商，越来越多的公司相继陷入这一泥潭；各国央行因此罕见地干预了货币市场，道琼斯工业股票平均价格指数周四收盘更是因此创下今年以来的第二大跌幅。

关键词：住房抵押贷款美国法国巴黎银行市场危机货币市场价格指数道琼斯信贷

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第一类超导体的动态电阻

低温与超导 1982年第2期 72-74+79页

作者： N.gauthier P.Rochon 景桂兰大连光明化工所

本文提出了处于居间态的 S;（第Ⅰ类超导体）动态电阻特性线性扰动理论的计算方法。我们采用广泛伦敦模型,对长直导线情况提出了该方法的求解,并介绍此方法获得的若干结果。

关键词：居间态超导态临界电流导线动态电阻函数电阻特性瞬时电压方程趋肤深度动态阻抗线性扰动伦敦表达式

Compliance with First-Line AntiRetroViral Treatment (ART) for HIV Infection in the Era of Dolutegravir in Kinshasa, Democratic Republic of the Congo

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World Journal of AIDS 2023年第1期13卷 11-17页

作者： Berry Ikolango Bongenya Marie-Thérèse Ayanne Safi Sombo Guy Makila Mabe Bumoko Benoit Obel Kabengele Mariano Manzo Lusakibanza gauthier Kahunu Mesia Erick Ntambwe Kamangu Faculty of Medicine Bel Campus Technological University Kinshasa Democratic Republic of the Congo “HIV/AIDS Focus” Research Group Kinshasa Democratic Republic of the Congo Department of Neurology Faculty of Medicine University of Kinshasa Kinshasa Democratic Republic of the Congo Department of Internal Medicine University Clinic Faculty of Medicine University of Kinshasa Democratic Republic of the Congo Clinical Pharmacology Service Department of Pharmacovigilance Faculty of Pharmaceutical Sciences University of Kinshasa Kinshasa Democratic Republic of the Congo Service of Molecular Biochemistry Department of Basic Sciences Faculty of Medicine University of Kinshasa Kinshasa Democratic Republic of the Congo

Context: Two years after the transition to Dolutegravir (DTG), at the national level, data on compliance with the execution of this transition and the rational use of the new molecule are not available. Objective: The objective of this study was to determine compliance with first-line ART prescriptions among People Living with HIV starting AntiRetroViral treatment in Kinshasa during the Dolutegravir era. Methods: This study is a descriptive cross-sectional study to determine compliance with first-line ART prescriptions among people living with HIV during the Dolutegravir era in Kinshasa. Sixteen Outpatients Treatment Centers (OTCs) were included in the study for their expertise in the care of PLHIV, their technical collection platform and their accessibility. The parameters of interest were: age, sex, outpatient treatment centers, and medical prescription. Results: One hundred and nineteen (119) patients were included in this work in accordance with the inclusion criteria;67 (56.3%) are female, giving a sex ratio of 1.29 in favor of women. The average age of the patients included is 39.87 ± 12.36 years with extremities of 18 to 69 years. The most represented age group is that of 36 to 45 years with 37 patients (31.9%). One hundred and nineteen (119) patients were received from 16 centers in Kinshasa, according to 6 OTC for the district of Funa, 4 OTC for Tshangu and 3 OTC respectively for Lukunga and Mont-Amba. All the centers respect the new recommendations of the National Program;all patients (100%) are on the Tenofovir (TDF) + Lamivudine (3TC) + Dolutegravir (DTG) combination. Conclusion: Compliance with the prescription of DTG as a first-line ARV in the DRC is effective in the city province of Kinshasa.

关键词： ART Profile Dolutegravir Kinshasa

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可降解含氮聚酯的合成与性能

化工新型材料 2022年第4期50卷 283-286页

作者：熊景程正载陈俊 Wandji Djouonkep Lesly Dasilva Seigu William Mawuko 孙欣贾如艳袁贝贝 Mario gauthier 武汉科技大学化学与化工学院精细有机化工与有机材料研究所武汉430081 煤转化与新型炭材料湖北省重点实验室武汉430081

以N-(羧甲基)甘氨酸和对苯二酚二(2-羟乙基)醚为主要原料,三氧化二锑为催化剂,采用熔融聚合法,合成聚[N-(羧甲基)甘氨酸-对苯二酚二(2-羟乙基)醚]酯(P1)。采用FT-IR、1H-NMR对聚酯P1结构进行了表征;采用GPC、DSC、TGA测试其分子量和热性... 详细信息

以N-(羧甲基)甘氨酸和对苯二酚二(2-羟乙基)醚为主要原料,三氧化二锑为催化剂,采用熔融聚合法,合成聚[N-(羧甲基)甘氨酸-对苯二酚二(2-羟乙基)醚]酯(P1)。采用FT-IR、1H-NMR对聚酯P1结构进行了表征;采用GPC、DSC、TGA测试其分子量和热性能;并采用自然掩埋法,对其在土壤中的降解性能进行了研究。GPC测试结果表明,该聚酯具有较高的分子量,Mn为41500g/mol。TG结果显示,该聚酯有良好的热稳定性,起始热分解温度高于333℃。在自然土壤环境下,聚酯P1经过两年的降解,分子量下降20%,降解性能好,具有良好发展前景。

关键词：含氮聚酯N-(羧甲基)甘氨酸可降解熔融聚合

Chronic hepatitis B liver disease in patients living in the Amazon region: S gene mutations and genotypes characterization

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World Journal of Cardiovascular Diseases 2013年第8期3卷 506-511页

作者： Deusilene Vieira Marie gauthier Larissa Deadame de Figueiredo Nicolete Alcione Oliveira dos Santos Carina Picelli Eduardo Honda Glaucia Paranhos-Baccala Guy Vernet Juan Miguel Villalobos Salcedo Research Center for Tropical Medicine CEPEM/Tropical Pathology Research InstituteFiocruz RondoniaRio de JaneiroBrazil Emerging Pathogens Laboratory Fondation MerieuxIFR 128 BioSciences GerlandLyonFrance

The Amazon region is considered to be a high endemic area for Hepatitis B Virus (HBV) infections, Rondônia state having the highest prevalence. The aim of this study was to identify molecular genotypes and mutations in the S gene region of HBV viral genomes from 20 patients using a DNA microarray. Results: Serological tests showed that 88% of patients were HBeAg negative, 82% had anti-HBe antibodies and 33% were co-infected with Hepatitis Delta Virus. Sixteen percent of the patients were considered cirrhotic, and 11% have been transfused. The microarray technique identified the genotypes A (4 patients), D (7 patients) and F (7 patients) in 18 samples. Mutations were detected in all 3 genotypes and, overall, A159G, which has been associated with a reduced antigenicity of the virus, was detected most frequently. In genotype A, G119E was the most frequently detected mutation followed by mutations A159G, F134Y, W172C, Y161F and T143S. A159G was detected in all genotype D and F samples followed by mutations T143S, Y161F, N131T, T114S and G119E in genotype D and mutations T143S, Y161F, N131T, T114S and G119E in genotype F. Conclusion: The analysis of mutations repartition among genotypes suggests that some of them are preferentially or exclusively associated with genotype A, D or F. This type of tool is adapted for clinical and therapy monitoring of patient as well as for molecular epidemiology research on HBV.

关键词： Hepatitis B Virus Mutant Detection DNA Microarray Amazon Region

术中门静脉测压对胆道闭锁患儿Kasai术后的预后评估

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临床外科杂志 2006年第5期14卷 294-296页

作者：朱坚韩天权张圣道 Frédéric gauthier 上海交通大学医学院附属瑞金医院普外科 200025 法国巴黎大学附属医学中心(CHU)Bicêtre医院儿外科

目的采用术中门静脉压力测定对胆道闭锁患儿Kasai术后的预后评估。方法1990年1月至1996年12月,法国巴黎Bic毢tre医院儿外科共对127例胆道闭锁患儿行Kasai手术或其变异术式,其中113例术中脐静脉插管行门静脉压力测定,术后平均随访9年。... 详细信息

目的采用术中门静脉压力测定对胆道闭锁患儿Kasai术后的预后评估。方法1990年1月至1996年12月,法国巴黎Bic毢tre医院儿外科共对127例胆道闭锁患儿行Kasai手术或其变异术式,其中113例术中脐静脉插管行门静脉压力测定,术后平均随访9年。分别计算患儿带自体肝生存率和带自体肝且无门静脉高压生存率,进行比较;依据患儿手术时的年龄,胆道闭锁的类型,手术方式,有无polysplenia综合征以及术时门静脉压力对生存率进行评估。结果术中门脉压力正常患儿带自体肝5年和10年生存率较门静脉压力升高组显著延长。门静脉压力升高组5年带自体肝且无门静脉高压表现的生存率显著低于门静脉压力正常组。胆道闭锁的类型和门静脉压力改变较其他指标更显著反映对Kasai术后预后影响。结论术前门静脉压力改变对Kasai术后的预后有显著性指导意义,并且优于其他指标。

关键词：胆道闭锁 Kasai手术门脉压力预后

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追责银行客户数据泄露

财经 2010年第15期 92-92页

作者： David gauthier-Villars Deborah Ball

前汇丰控股员工拷贝了数千份汇丰瑞士私人银行客户文件。法国当局目前正在利用此数据追查逃税者，并将其交给其他国家。此事震动了银行界。

关键词：银行客户客户数据银行界私人控股逃税

对妊娠母猪精准饲喂的一个决策支持系统评估(下)

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猪业科学 2021年第2期38卷 20-23页

作者：何颖(译) Charlotte Gaillard Nathalie Quiniou Raphael gauthier Laetitia Cloutier Jean-Yves Dourmad 辽宁禾丰牧业股份有限公司辽宁鞍山114100 不详

前报道的使用精准饲喂模式(PF),将2种不同赖氨酸水平的日粮(高赖氨酸-H,低赖氨酸-L)进行不同比例混合后饲喂生长育肥猪,相对于基于单一配方的日粮(C)的传统饲喂模式(CF),可以减少蛋白摄入和N排放。使用基于猪场数据的模拟方法,文章旨在... 详细信息

前报道的使用精准饲喂模式(PF),将2种不同赖氨酸水平的日粮(高赖氨酸-H,低赖氨酸-L)进行不同比例混合后饲喂生长育肥猪,相对于基于单一配方的日粮(C)的传统饲喂模式(CF),可以减少蛋白摄入和N排放。使用基于猪场数据的模拟方法,文章旨在描述和评估精准饲喂妊娠母猪的一个决策支持系统,该系统允许给每头母猪每天供应一个定制日粮。有两个数据组,猪场A中有2511头妊娠母猪,猪场B中有2528头妊娠母猪,在电子设备上通过构建Python模型,在授精时输入母猪特征并在产仔时输入具体目标。该模型主要基于InraPorc,计算每头母猪整个妊娠期的营养需要,并模拟了PF相对于CF的影响。模拟日粮L、H和C分别含有标准回肠可消化赖氨酸(SID Lys)3.0 g/kg、6.5 g/kg和4.8 g/kg,标准总肠道可消化磷(STTD-P)2.0 g/kg、3.3 g/kg和2.5 g/kg。采用混合模型分析猪场、胎次、妊娠周对SID Lys和STTD-P计算需要的影响程度以及三者的互作效应。在妊娠期后三分之一阶段,SID Lys和STTD-P计算需要量显著增加(P<0.01),且初产母猪的需要高于经产母猪,但是妊娠14周后的STTD-P需要例外。猪场B的SID AA和矿物元素计算需要量低于猪场A(SID AA分别为2.93 g/kg和3.08 g/kg,STTD-P分别是1.30 g/kg和1.35 g/kg,P<0.01)。通过PF模式进行的饲喂方案,猪场A和猪场B平均饲喂L日粮占总日粮的86%和92%。相比于CF,猪场A和猪场B通过PF模式的平均日粮SID Lys计算含量要低27%和32%,而平均日粮磷计算含量要低13%和16%。对于SID Lys缺乏或过量的母猪模拟比例可通过PF来减少。相比于CF,PF模式使每头母猪在妊娠期的模拟饲料损耗减少3.6%,并同时减少氮和磷的摄入(分别减少11.0%和13.8%)和排出(分别减少16.7%和15.4%)。综上所述,这些模拟计算表明:妊娠母猪精准饲喂,呈现出满足氨基酸需要的同时,减少饲料损耗以及氮、磷的摄入和排泄。

关键词：氨基酸环境妊娠母猪矿物元素营养精准饲喂

Contraception among Women Aged 35 and over at the University Hospital Center of Brazzaville

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Open Journal of Obstetrics and Gynecology 2024年第11期14卷 1716-1725页

作者： Mpia Nuelly Samantha Bialay Potokoué gauthier Régis Jostin Buambo Jean Timothée Ekani Max Lévy Emery Eouani Jules César Mokoko Clautaire Itoua Léon HervéIloki Department of Gynecology and Obstetrics UHC of Brazzaville Brazzaville Republic of the Congo Department of Gynecology and Obstetrics Loandjili General Hospital Pointe Noire Republic of the Congo

Objective: To study contraception among women aged 35 and over at the University Hospital of Brazzaville. Population and Methods: This was a retrospective descriptive study, conducted from April 1st 2017 to January 31st 2022 in the Obstetrics and Gynecology Department of the University Hospital of Brazzaville, including women aged 35 years and over who had received a contraceptive method. The study variables were sociodemographic, reproductive, clinical and contraceptive method related. Results: Two hundred and thirty customers were collected during the study period, i.e., 10.8% of the patients who received contraception. They were 38.4 ± 3 years old on average, had secondary education (46.1%), were of low socioeconomic status (54.3%), lived with a partner (98.7%) and came from an urban area (97.4%). They were multigravida (85.2%), and multiparous (63.9%) with an average of 4 living children. The indications were of two types: convenience (26.2%) and medical (73.8%). The most commonly used contraceptives were implants (72.2%) and injectable progestin (20.5%). Conclusion: The indication for contraception for women over 35 years of age at the University Hospital Center of Brazzaville is more medical, with the use of long-acting contraceptives.

关键词： Contraception Women Aged 35 and over Brazzaville