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Relationship between acute hypercarbia and hyperkalaemia during surgery

World Journal of Clinical Cases 2019年第22期7卷 3711-3717页

作者： Laurence Weinberg Amelia Russell Lois Mackley Charles Dunnachie Joshua Meyerov Chong Tan Michael Li raymond hu Dharshi Karalapillai Department of Anaesthesia Austin HealthMelbourneVictoria 3084Australia Department of Intensive Care Austin HealthMelbourneVictoria 3084Australia Melbourne Medical School University of MelbourneVictoria 3010Australia

BACKGROUND The relationship between hyperkalaemia and metabolic acidosis is well described in the critical care setting;however,the relationship between acute respiratory acidosis and plasma potassium concentration is less well *** a controlled model of increasing levels of hypercarbia,we tested the hypothesis of whether increasing levels of hypercarbia are associated with changes in plasma potassium *** To determine whether increasing levels of hypercarbia are associated with changes in plasma potassium *** We performed a post-hoc study examining changes in serum potassium in 24 patients who received increased levels of hypercarbia during cardiac *** blood gases and plasma concentrations of potassium were measured at baseline,3 min prior to,and then every 3 min for 15 min during the intervention of *** primary endpoint was the absolute change in serum K+at 15 min compared to the baseline K+*** following secondary endpoints were evaluated:(1)The association between CO2 and serum K+concentration;and(2)The correlation between plasma pH and serum K+*** During the intervention,PaCO2 increased from 43.6 mmHg(95%CI:40.1 to 47.1)at pre-intervention to 83.9 mmHg(95%CI:78.0 to 89.8)at 15 min after intervention;P<*** mean(SD)serum potassium increased from 4.16(0.35)mmol/L at baseline to 4.28(0.33)mmol/L at 15 min(effect size 0.09 mol/L;P=0.22).There was no significant correlation between PaCO2 and potassium(Pearson’s coefficient 0.06;95%CI:-0.09 to 0.21)or between pH and potassium(Pearson’s coefficient-0.07;95%CI:-0.22 to 0.09).CONCLUSION Acute hypercarbia and subsequent respiratory acidaemia were not associated with hyperkalaemia in patients undergoing major surgery.

关键词： Anaesthesia Intensive care Biochemistry Surgery

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压实技术的飞跃——宝马研制中的GPS全球定位系统技术

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工程机械与维修 2003年第6期 82-83页

作者： raymond hu 北京市朝阳区霄云路26号鹏润大厦5层B502-503室100016

宝马做为全球压实技术的引导者,在成功地推出了BOM、BTM、BCM等压实质量监测和记录系统与'智多星'(BVC)智能压实系统后,又开始将GPS全球卫星定位系统应用到压实领域.这套系统不仅可以实现远程的施工质量检测,还可以逐渐应用于远程控制,... 详细信息

宝马做为全球压实技术的引导者,在成功地推出了BOM、BTM、BCM等压实质量监测和记录系统与'智多星'(BVC)智能压实系统后,又开始将GPS全球卫星定位系统应用到压实领域.这套系统不仅可以实现远程的施工质量检测,还可以逐渐应用于远程控制,从而实现压路机的无人驾驶.这无疑是压实技术的一个重大突破.

关键词：压路机压实技术 GPS 全球卫星定位系统智能压实系统远程控制无人驾驶

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HYPOPIGMENTATION AND HEALTHY SKIN PROMOTING EFFECT OF A MODIFIED QI BAI SAN

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World Journal of Traditional Chinese Medicine 2016年第2期 81-82页

作者： Elaine Wat Yau Tsz Chan Tiffany Hoi Ka Tso Chun Fai Ng Ching Po Lau Wing Sum Siu Chun Hay Ko Ka Keung Lau raymond hu Clara Bik-San Lau Ping Chung Leung Institute of Chinese Medicine and State Key Laboratory of Phytochemistry and Plant Resources in West China The Chinese University of Hong Kong 5100 Cosmetic Company Ltd.

Introduction:Qi Bai San(QBS,七白散)is a traditional Chinese herbal formula used by ancient ladies for healthy skin and *** it is a popular product in the market,it contains animal drug and toxic herbs which

关键词： MSH HYPOPIGMENTATION AND HEALTHY SKIN PROMOTING EFFECT OF A MODIFIED QI BAI SAN

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Profit Guided or Statistical Error Guided? A Study of Stock Index Forecasting Using Support Vector Regression

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Journal of Systems Science & Complexity 2017年第6期30卷 1425-1442页

作者： hu Zhongyi BAO Yukun CHIONG raymond XIONG Tao School of Information Management Wuhan University School of Management Huazhong University of Science and Technology School of Electrical Engineering and Computing The University of Newcastle College of Economics and Management Huazhong Agricultural University

Stock index forecasting has been one of the most widely investigated topics in the field of financial forecasting. Related studies typically advocate for tuning the parameters of forecasting models by minimizing learning errors measured using statistical metrics such as the mean squared error or mean absolute percentage error. The authors argue that statistical metrics used to guide parameter tuning of forecasting models may not be meaningful, given the fact that the ultimate goal of forecasting is to facilitate investment decisions with expected profits in the future. The authors therefore introduce the Sharpe ratio into the process of model building and take it as the profit metric to guide parameter tuning rather than using the commonly adopted statistical metrics. The authors consider three widely used trading strategies, which include a na¨?ve strategy, a filter strategy and a dual moving average strategy, as investment scenarios. To verify the effectiveness of the proposed profit guided approach, the authors carry out simulation experiments using three global mainstream stock market indices. The results show that profit guided forecasting models are competitive, and in many cases produce significantly better performances than statistical error guided models. This implies thatprofit guided stock index forecasting is a worthwhile alternative over traditional stock index forecasting practices.

关键词： Financial market investment trading strategy parameter optimization stock index forecasting support vector regression

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走出封闭的房间:雷蒙·威廉斯的电影活动与文化观念

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北京电影学院学报 2024年第6期 69-77页

作者：胡亮宇北京语言大学文学院

英国文化研究的先驱雷蒙·威廉斯对电影有着长期的思考和研究,他将电影视为融合文化传统、先锋形式及大众教育功能的新兴媒介,在现代社会中扮演着重要角色。威廉斯对电影的认识,不仅体现了文化研究的问题意识和方法,也折射出其学术思想... 详细信息

英国文化研究的先驱雷蒙·威廉斯对电影有着长期的思考和研究,他将电影视为融合文化传统、先锋形式及大众教育功能的新兴媒介,在现代社会中扮演着重要角色。威廉斯对电影的认识,不仅体现了文化研究的问题意识和方法,也折射出其学术思想和文化观念的演变。本文旨在回顾威廉斯的电影活动,总结其相关论述的核心要点,并尝试以文化研究的思路,考察电影在其理论事业中的地位,思考威廉斯的电影研究对当今学界和社会的启示。

关键词：雷蒙·威廉斯文化研究电影理论情感结构

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Atomic defects,functional groups and properties in MXenes

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Chinese Chemical Letters 2021年第1期32卷 339-344页

作者： Wenjun Cui Zhi-Yi hu raymond RUnocic Gustaaf Van Tendeloo Xiahan Sang State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of TechnologyWuhan 430070China NRC(Nanostructure Research Centre) Wuhan University of TechnologyWuhan 430070China Center for Nanophase Materials Sciences Oak Ridge National LaboratoryOak RidgeTN 37831United States EMAT(Electron Microscopy for Materials Science) University of AntwerpAntwerpB-2020Belgium

MXenes,a new family of functional two-dimensional(2 D) materials,have shown great potential for an extensive variety of applications within the last *** defects and functional groups in MXenes are known to have a tremendous influence on the functional *** this review,we focus on recent progress in the characterization of atomic defects and functional group chemistry in MXenes,and how to control them to directly influence various properties(e.g.,electron transport,Li^(+) adsorption,hydrogen evolution reaction(HER) activity,and magnetism) of 2 D MXenes *** structural transformations such as oxidation and growth induced by atomic defects in MXenes are also *** review thus provides perspectives on property optimization through atomic defect engineering,and bottom-up synthesis methods based on defect-assisted homoepitaxial growth of MXenes.

关键词： MXenes Atomic defects Surface functional groups Electron microscopy Functional properties

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Predicting synthesizable multi-functional edge reconstructions in two-dimensional transition metal dichalcogenides

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npj Computational Materials 2020年第1期6卷 1314-1322页

作者： Guoxiang hu Victor Fung Xiahan Sang raymond R.Unocic P.Ganesh Center for Nanophase Materials Sciences Oak Ridge National LaboratoryOak RidgeTN 37831USA

Two-dimensional(2D)transition metal dichalcogenides(TMDCs)have attracted tremendous interest as functional materials due to their exceptionally diverse and tunable properties,especially in their *** addition to the conventional armchair and zigzag edges common to hexagonal 2D materials,more complex edge reconstructions can be realized through careful control over the synthesis ***,the whole family of synthesizable,reconstructed edges remains poorly ***,we develop a computational approach integrating ensemble-generation,force-relaxation,and electronic-structure calculations to systematically and efficiently discover additional reconstructed edges and screen their functional properties.

关键词： functional dimensional integrating

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MR-seq:measuring a single cell's transcriptome repeatedly by RNA-seq

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Science Bulletin 2017年第6期62卷 391-398页

作者： Lu Yang Zhaochun Ma Chen Cao Yuhao Zhang Xinglong Wu raymond Lee Boqiang hu Lu Wen Hao Ge Yanyi huang Kaiqin Lao Fuchou Tang Biodynamic Optical Imaging Center School of Life Sciences Peking University Beijing 100871 China Thermo Fisher Scientific.South San Francisco CA 94080 USA Peking-Tsinghua Center for Life Sdences Beijing 100084 China Beijing International Center for Mathematical Research (BICMR) Peking University Beijing 100871 China College of Engineering Peking University Beijing 100871 China China Center for Molecular and Translationai Medicine (CMTM) Beijing 100101 China Beijing Advanced Innovation Center for Cenomics (ICG) Peking University Beijing 100871 China

We described a novel single-cell RNA-seq technique called MR-seq （measure a single-cell transcriptome repeatedly）, which permits statistically assessing the technical variation and identifying the differentially expressed genes between just two single ceils by measuring each single cell twice. We demonstrated that MR-seq gave sensitivity and reproducibility similar to the standard single-cell RNA-seq and increased the positive predicate value, Application of MR-seq to early mouse embryos identified hundreds of candidate intra-embryonic heterogeneous genes among mouse 2-, 4- and 8-cell stage embryos. MR-seq should be useful for detecting differentially exnre^ed ~enes ~rnnn~ ~ ~m^ll nHmhpr nf c^ll~

关键词： Single-cell RNA-seqDifferentially expressed geneslntra-embryonic heterogeneity Mouse early preimplantation embryos

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Genome survey uncovers the secrets of sex and lifestyle in caterpillar fungus

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Chinese Science Bulletin 2013年第23期58卷 2846-2854页

作者： hu Xiao ZHANG YongJie XIAO Guohua ZHENG Peng XIA YongLiang ZHANG XingYu ST LEGER raymond J LIU XingZhong WANG ChengShu Key Laboratory of Insect Developmental and Evolutionary Biology Institute of Plant physiology and Ecology Shanghai Institutes for Biological Sciences Chinese Academy of Sciences School of Life Sciences Shanxi University State Key Laboratory of Mycology Institute of Microbiology Chinese Academy of Sciences Department of Entomology University of Maryland College Park

The caterpillar fungus Ophiocordyceps sinensis (best known as Cordyceps sinensis) mummifies ghost moth larvae exclusively in Tibetan Plateau alpine ecosystems. Touted as "Himalayan Viagra", the fungus is highly prized due to its medical benefits and dwindling supplies. Attempts to culture the sexual fruiting-body have failed and the huge market demand has led to severe devastation of local ecosystems and to the fungus heading towards extinction. By genome sequencing, we establish that unlike related insect pathogens O. sinensis contains two compatible mating-type genes in its genome and is self-fertile, i.e. homothallic. However, sexual processes are only initiated under native environmental conditions. O. sinensis resembles biotrophic plant pathogens in having a genome shaped by retrotransposon-driven expansions. The resulting changes in gene content suggest that O. sinensis has a biphasic pathogenic mechanism beginning with stealth pathogenesis in early host instars. O. sinensis is the first psychrophilic fungus sequenced and is adapted to extreme cold with putative antifreeze proteins and mechanisms for increasing lipid accumulation and fatty acid unsaturation. We hypothesize that for the inbreeding O. sinensis the massive proliferation of retrotransposons provides a tradeoff between the advantages of increased genetic variation independent of sexual recombination and deletion of genes dispensable for its specialized pathogenic lifestyle.

关键词：基因组测序生活方式虫草秘密性反转录转座子冬虫夏草致病机制不饱和脂肪酸

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全球的在地——安东宁·雷蒙德的建筑思想演变与在日设计实践

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建筑学报 2024年第5期 93-100页

作者：胡雅婷杨涛袁唐鹏赟湖南大学建筑与规划学院长沙410082 同济大学建筑与城市规划学院上海200092

以美籍捷克裔建筑师安东宁·雷蒙德的作品与思想作为解读对象,梳理了以赖特、奥古斯特·佩雷、勒·柯布西耶为代表的建筑师对其建筑探索过程中的阶段性影响,阐述了雷蒙德作为一个“外来者”如何在建筑设计中逐步巧妙地将日本与西方的建... 详细信息

以美籍捷克裔建筑师安东宁·雷蒙德的作品与思想作为解读对象,梳理了以赖特、奥古斯特·佩雷、勒·柯布西耶为代表的建筑师对其建筑探索过程中的阶段性影响,阐述了雷蒙德作为一个“外来者”如何在建筑设计中逐步巧妙地将日本与西方的建造技术方法、生活方式、精神文化彼此圆融,从而使传统与现代共同服务于最终的建筑目的,并指出其设计思想与实践的当代建筑学价值。

关键词：安东宁·雷蒙德现代建筑日本建筑赖特奥古斯特·佩雷勒·柯布西耶跨文化

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